SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites

Cancer Prevention Research

Volumn 7, Issue 5, 2014, Pages 505-515

  Hemachandra, L P Madhubhani P ^a   Patel, Hitisha ^a   Chandrasena, R Esala P ^a   Choi, Jaewoo ^a   Piyankarage, Sujeewa C ^a   Wang, Shuai ^a   Wang, Yijin ^a   Thayer, Emily N ^a   Scism, Robert A ^a   Michalsen, Bradley T ^a   Xiong, Rui ^a   Siklos, Marton I ^a   Bolton, Judy L ^a   Thatcher, Gregory R J ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFIMOXIFENE; ARZOXIFENE; BAZEDOXIFENE; BETA GLUCURONIDASE; RALOXIFENE; REACTIVE OXYGEN METABOLITE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SULFOTRANSFERASE; DESMETHYLARZOXIFENE; ESTRADIOL; INDOLE DERIVATIVE; OXIDIZING AGENT; PIPERIDINE DERIVATIVE; TAMOXIFEN; THIOPHENE DERIVATIVE;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; BREAST EPITHELIUM; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; CELL CULTURE; CELL PROTECTION; CELL TRANSFORMATION; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG INACTIVATION; MAMMARY GLAND; MCF 7 CELL LINE; METABOLISM; PATHOLOGY; UPREGULATION;

CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYTOPROTECTION; ESTRADIOL; HUMANS; INACTIVATION, METABOLIC; INDOLES; MAMMARY GLANDS, HUMAN; MCF-7 CELLS; OXIDANTS; OXIDATIVE STRESS; PIPERIDINES; RALOXIFENE; REACTIVE OXYGEN SPECIES; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TAMOXIFEN; THIOPHENES; UP-REGULATION;

EID: 84900801000     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-13-0296     Document Type: Article

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