Amino acid concentrations in critically Ill children following cardiac surgery

Pediatric Critical Care Medicine

Volumn 15, Issue 4, 2014, Pages 314-328

  Gielen, Marijke ^a   Vanhorebeek, Ilse ^a   Wouters, Pieter J ^a   Mesotten, Dieter ^a   Wernerman, Jan ^b,c   Van Den Berghe, Greet ^a   Rooyackers, Olav ^b,c  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Amino acids; Critical illness; Glucose control; Insulin; Mortality; Pediatrics

Indexed keywords

ALANINE; AMINO ACID; ARGININE; ASPARAGINE; ASPARTIC ACID; CYSTEINE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HISTIDINE; INSULIN; ISOLEUCINE; LEUCINE; LYSINE; METHIONINE; PHENYLALANINE; PROLINE; SERINE; TAURINE; THREONINE; TRYPTOPHAN; TYROSINE; VALINE; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL;

AMINO ACID BLOOD LEVEL; AMINO ACID DEFICIENCY; ARTICLE; BLOOD GLUCOSE MONITORING; COMPARATIVE STUDY; CONTROLLED STUDY; CRITICALLY ILL PATIENT; FEMALE; GLUCOSE BLOOD LEVEL; HEART SURGERY; HUMAN; INFANT; INSULIN INFUSION; INSULIN TREATMENT; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; NEWBORN; NUTRITION; NUTRITIONAL SUPPORT; PEDIATRIC SURGERY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL; SURVIVOR; TIME; AGE; BLOOD; CRITICAL ILLNESS; DRUG EFFECTS; METABOLISM; MORTALITY; NUTRITIONAL STATUS; PARENTERAL NUTRITION; POSTOPERATIVE PERIOD; SURVIVAL RATE;

AGE FACTORS; AMINO ACIDS; BLOOD GLUCOSE; CARDIAC SURGICAL PROCEDURES; CRITICAL ILLNESS; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INFANT; INFANT, NEWBORN; INSULIN; MALE; NUTRITIONAL STATUS; PARENTERAL NUTRITION; POSTOPERATIVE PERIOD; SURVIVAL RATE; TIME FACTORS;

EID: 84900543682     PISSN: 15297535     EISSN: 19473893     Source Type: Journal    
DOI: 10.1097/PCC.0000000000000075     Document Type: Article

References (43)

1. Singer P, Berger MM, Van den Berghe G, et al: ESPEN Guidelines on parenteral nutrition: Intensive care. Clin Nutr 2009; 28:387-400
2. Martindale RG, McClave SA, Vanek VW, et al; American College of Critical Care Medicine; A.S.P.E.N. Board of Directors: Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition: Executive summary. Crit Care Med 2009; 37:1757-1761
3. Heyland DK, Dhaliwal R, Drover JW, et al; Canadian Critical Care Clinical Practice Guidelines Committee: Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN J Parenter Enteral Nutr 2003; 27:355-373 (Pubitemid 37022781)
4. Verbruggen S, Sy J, Arrivillaga A, et al: Parenteral amino acid intakes in critically ill children: A matter of convenience. JPEN J Parenter Enteral Nutr 2010; 34:329-340
5. Yarandi SS, Zhao VM, Hebbar G, et al: Amino acid composition in parenteral nutrition: What is the evidence? Curr Opin Clin Nutr Metab Care 2011; 14:75-82
6. Guadagni M, Biolo G: Effects of inflammation and/or inactivity on the need for dietary protein. Curr Opin Clin Nutr Metab Care 2009; 12:617-622
7. Mehta NM, Compher C; A.S.P.E.N. Board of Directors: A.S.P.E.N. Clinical Guidelines: Nutrition support of the critically ill child. JPEN J Parenter Enteral Nutr 2009; 33:260-276
8. Klaude M, Mori M, Tjäder I, et al: Protein metabolism and gene expression in skeletal muscle of ICU patients with sepsis. Clin Sci 2012; 122:133-142
9. Rennie MJ, Bohé J, Wolfe RR: Latency, duration and dose response relationships of amino acid effects on human muscle protein synthesis. J Nutr 2002; 132:3225S-3227S
10. Roth E: Immune and cell modulation by amino acids. Clin Nutr 2007; 26:535-544
11. Garlick PJ: Assessment of the safety of glutamine and other amino acids. J Nutr 2001; 131:2556S-2561S
12. Briassoulis G, Tsorva A, Zavras N, et al: Influence of an aggressive early enteral nutrition protocol on nitrogen balance in critically ill children. J Nutr Biochem 2002; 13:560
13. van Waardenburg DA, de Betue CT, Luiking YC, et al: Plasma arginine and citrulline concentrations in critically ill children: Strong relation with inflammation. Am J Clin Nutr 2007; 86:1438-1444 (Pubitemid 350126249)
14. van Waardenburg DA, de Betue CT, Goudoever JB, et al: Critically ill infants benefit from early administration of protein and energy-enriched formula: A randomized controlled trial. Clin Nutr 2009; 28:249-255
15. Zappitelli M, Juarez M, Castillo L, et al: Continuous renal replacement therapy amino acid, trace metal and folate clearance in critically ill children. Intensive Care Med 2009; 35:698-706
16. Vlasselaers D, Milants I, Desmet L, et al: Intensive insulin therapy for patients in paediatric intensive care: A prospective, randomised controlled study. Lancet 2009; 373:547-556
17. Mesotten D, Gielen M, Sterken C, et al: Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: A randomized controlled trial. JAMA 2012; 308:1641-1650
18. Shann F, Henning R, Shekerdemian L (Eds): Paediatric Intensive Care Guidelines. Third Edition. Victoria, Collective, 2008
19. Gore DC, Chinkes DL, Hart DW, et al: Hyperglycemia exacerbates muscle protein catabolism in burn-injured patients. Crit Care Med 2002; 30:2438-2442 (Pubitemid 35351860)
20. Cynober LA: Plasma amino acid levels with a note on membrane transport: Characteristics, regulation, and metabolic significance. Nutrition 2002; 18:761-766
21. Langouche L, Vander Perre S, Wouters PJ, et al: Effect of intensive insulin therapy on insulin sensitivity in the critically ill. J Clin Endocrinol Metab 2007; 92:3890-3897 (Pubitemid 47607638)
22. Hammarqvist F, Angsten G, Meurling S, et al: Age-related changes of muscle and plasma amino acids in healthy children. Amino Acids 2010; 39:359-366
23. Brown TC, Connelly JF, Dunlop ME, et al: Fasting plasma glucose in children. Aust Paediatr J 1980; 16:28-29 (Pubitemid 10107810)
24. Vesali RF, Klaude M, Rooyackers OE, et al: Longitudinal pattern of glutamine/glutamate balance across the leg in long-stay intensive care unit patients. Clin Nutr 2002; 21:505-514 (Pubitemid 35446850)
25. Powell-Tuck J: Nutritional interventions in critical illness. Proc Nutr Soc 2007; 66:16-24
26. Vanhorebeek I, Van den Berghe G: Hormonal and metabolic strategies to attenuate catabolism in critically ill patients. Curr Opin Pharmacol 2004; 4:621-628 (Pubitemid 40267878)
27. Premji SS, Fenton TR, Sauve RS: Higher versus lower protein intake in formula-fed low birth weight infants. Cochrane Database Syst Rev 2006; CD003959
28. Pierro A, Eaton S: Metabolism and nutrition in the surgical neonate. Semin Pediatr Surg 2008; 17:276-284
29. Brunton JA, Ball RO, Pencharz PB: Current total parenteral nutrition solutions for the neonate are inadequate. Curr Opin Clin Nutr Metab Care 2000; 3:299-304 (Pubitemid 30469065)
30. Kamata S, Imura K, Kawahara H, et al: Early postoperative change of plasma levels of amino acids in neonates with perforative peritonitis and its prognostic significance. J Pediatr Surg 1995; 30: 559-562
31. Vanhorebeek I, Gunst J, Derde S, et al: Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab 2011; 96:E633-E645
32. Derde S, Vanhorebeek I, Güiza F, et al: Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology 2012; 153:2267-2276
33. Eskelinen EL, Saftig P: Autophagy: A lysosomal degradation pathway with a central role in health and disease. Biochim Biophys Acta 2009; 1793:664-673
34. Komatsu M, Ichimura Y: Selective autophagy regulates various cellular functions. Genes Cells 2010; 15:923-933
35. Glick D, Barth S, Macleod KF: Autophagy: Cellular and molecular mechanisms. J Pathol 2010; 221:3-12
36. Meijer AJ: Amino acid regulation of autophagosome formation. Methods Mol Biol 2008; 445:89-109
37. Derde S, Vanhorebeek I, Ververs EJ, et al: Increasing intravenous glucose load in the presence of normoglycemia: Effect on outcome and metabolism in critically ill rabbits. Crit Care Med 2010; 38:602-611
38. Biolo G, De Cicco M, Lorenzon S, et al: Treating hyperglycemia improves skeletal muscle protein metabolism in cancer patients after major surgery. Crit Care Med 2008; 36:1768-1775
39. Gore DC, Wolf SE, Sanford AP, et al: Extremity hyperinsulinemia stimulates muscle protein synthesis in severely injured patients. Am J Physiol Endocrinol Metab 2004; 286:E529-E534 (Pubitemid 38374949)
40. Agus MS, Steil GM, Wypij D, et al; SPECS Study Investigators: Tight glycemic control versus standard care after pediatric cardiac surgery. N Engl J Med 2012; 367:1208-1219
41. Alsweiler JM, Harding JE, Bloomfield FH: Tight glycemic control with insulin in hyperglycemic preterm babies: A randomized controlled trial. Pediatrics 2012; 129:639-647
42. Lepage N, McDonald N, Dallaire L, et al: Age-specific distribution of plasma amino acid concentrations in a healthy pediatric population. Clin Chem 1997; 43:2397-2402 (Pubitemid 28022978)
43. Casaer MP, Mesotten D, Hermans G, et al: Early versus late parenteral nutrition in critically ill adults. N Engl J Med 2011; 365:506-517