Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength

American Journal of Physiology - Endocrinology and Metabolism

Volumn 306, Issue 8, 2014, Pages

  Brisson, Becky K ^a   Spinazzola, Janelle ^a   Park, Soo Hyun ^a   Barton, Elisabeth R ^a  

^a UNIVERSITY OF PENNSYLVANIA SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

Adeno associated viral vectors; E peptides; Hypertrophy; IGF I; Skeletal muscle

Indexed keywords

METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDE E; POLYPEPTIDE; PROTEIN KINASE B; RNA ISOFORM; SOMATOMEDIN C; VALINE; VIRUS VECTOR;

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; EVOLUTIONARY HOMOLOGY; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; MUSCLE HYPERTROPHY; MUSCLE MASS; MUSCLE STRENGTH; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SATELLITE CELL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; VIRUS EXPRESSION;

ADENO-ASSOCIATED VIRAL VECTORS; E-PEPTIDES; HYPERTROPHY; IGF-I; SKELETAL MUSCLE;

3T3 CELLS; ANIMALS; DEPENDOVIRUS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, INBRED C57BL; MUSCLE STRENGTH; MUSCLE, SKELETAL; ORGAN SIZE; PEPTIDE FRAGMENTS;

EID: 84900535212     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00008.2014     Document Type: Article

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