Expression of IGF-1 isoforms after exercise-induced muscle damage in humans: Characterization of the MGF E peptide actions in vitro

In Vivo

Volumn 23, Issue 4, 2009, Pages 567-576

  Philippou, A ^a   Papageorgiou, E ^a   Bogdanis, G ^b   Halapas, A ^a   Sourla, A ^c   Maridaki, M ^b   Pissimissis, N ^a   Koutsilieris, M ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c Endo/OncoResearch Medical Laboratories   (Greece)

Author keywords

Eccentric exercise; MGF signalling; Myoblast proliferation; Skeletal muscle regeneration

Indexed keywords

CREATINE KINASE; MESSENGER RNA; PROTEIN KINASE B; RECEPTOR ANTIBODY; SOMATOMEDIN C; SOMATOMEDIN C DERIVATIVE; SOMATOMEDIN C EA; SOMATOMEDIN C EB; SOMATOMEDIN C EC; SOMATOMEDIN C RECEPTOR; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; ECCENTRIC MUSCLE CONTRACTION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IN VITRO STUDY; ISOKINETIC EXERCISE; MALE; MOUSE; MUSCLE BIOPSY; MUSCLE EXERCISE; MUSCLE REGENERATION; MUSCLE STRESS; MYOBLAST; NONHUMAN; NORMAL HUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RNA TRANSLATION; SIGNAL TRANSDUCTION;

EID: 67650945282     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Proske U and Morgan DL: Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. J Physiol 537: 333-345, 2001. (Pubitemid 33130492)
2. Jones DA, Newham DJ, Round JM and Tolfree SE: Experimental human muscle damage: morphological changes in relation to other indices of damage. J Physiol 375: 435-448, 1986.
3. Charge SB and Rudnicki MA: Cellular and molecular regulation of muscle regeneration. Physiol Rev 84: 209-238, 2004. (Pubitemid 38049880)
4. Adams GR: Invited Review: Autocrine/paracrine IGF-I and skeletal muscle adaptation. J Appl Physiol 93: 1159-1167, 2002.
5. Philippou A, Maridaki M, Halapas A and Koutsilieris M: The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology. In Vivo 21: 45-54, 2007. (Pubitemid 46359198)
6. Philippou A, Maridaki M and Koutsilieris M: The role of urokinase-type plasminogen activator (uPA) and transforming growth factor beta 1 (TGFβ1) in muscle regeneration. In Vivo 22: 735-750, 2008.
7. Philippou A, Bogdanis GC, Nevill AM and Maridaki M: Changes in the angle-force curve of human elbow flexors following eccentric and isometric exercise. Eur J Appl Physiol 93: 237-244, 2004. (Pubitemid 39489832)
8. Bickel CS, Slade J, Mahoney E, Haddad F, Dudley GA and Adams GR: Time course of molecular responses of human skeletal muscle to acute bouts of resistance exercise. J Appl Physiol 98: 482-488, 2005.
9. Kim JS, Cross JM and Bamman MM: Impact of resistance loading on myostatin expression and cell cycle regulation in young and older men and women. Am J Physiol Endocrinol Metab 288: E1110-1119, 2005.
10. Hameed M, Orrell RW, Cobbold M, Goldspink G and Harridge SD: Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise. J Physiol 547: 247-254, 2003. (Pubitemid 36285178)
11. Philippou A, Stavropoulou A, Sourla A, Pissimissis N, Halapas A, Maridaki M and Koutsilieris M: Characterization of a rabbit antihuman mechano growth factor (MGF) polyclonal antibody against the last 24 amino acids of the E domain. In Vivo 22: 27-35, 2008.
12. Koutsilieris M, Rabbani SA, Bennett HP and Goltzman D: Characteristics of prostate-derived growth factors for cells of the osteoblast phenotype. J Clin Invest 80: 941-946, 1987. (Pubitemid 18075626)
13. Yang SY and Goldspink G: Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation. FEBS Lett 522: 156-160, 2002.
14. Papageorgiou E, Pitulis N, Manoussakis M, Lembessis P and Koutsilieris M: Rosiglitazone attenuates insulin-like growth factor 1 receptor survival signaling in PC-3 cells. Mol Med 14: 403-411, 2008.
15. Gilmour RS: The implications of insulin-like growth factor mRNA heterogeneity. J Endocrinol 140: 1-3, 1994. (Pubitemid 2047005)
16. Shavlakadze T, Winn N, Rosenthal N and Grounds MD: Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle. Growth Horm IGF Res 15: 4-18, 2005. (Pubitemid 40220850)
17. Siegfried JM, Kasprzyk PG, Treston AM, Mulshine JL, Quinn KA and Cuttitta F: A mitogenic peptide amide encoded within the E peptide domain of the insulin-like growth factor IB prohormone. Proc Natl Acad Sci USA 89: 8107-8111, 1992.
18. Kuo YH and Chen TT: Novel activities of pro-IGF-I E peptides: regulation of morphological differentiation and anchorage-independent growth in human neuroblastoma cells. Exp Cell Res 280: 75-89, 2002.
19. Ates K, Yang SY, Orrell RW, Sinanan AC, Simons P, Solomon A, Beech S, Goldspink G and Lewis MP: The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle. FEBS Lett 581: 2727-2732, 2007. (Pubitemid 46829121)
20. Mills P, Dominique JC, Lafreniere JF, Bouchentouf M and Tremblay JP: A synthetic mechano growth factor E Peptide enhances myogenic precursor cell transplantation success. Am J Transplant 7: 2247-2259, 2007. (Pubitemid 47347850)
21. Florini JR, Ewton DZ and Coolican SA: Growth hormone and the insulin-like growth factor system in myogenesis. Endocr Rev 17: 481-517, 1996. (Pubitemid 26346639)
22. Coolican SA, Samuel DS, Ewton DZ, McWade FJ and Florini JR: The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J Biol Chem 272: 6653-6662, 1997.
23. Philippou A, Halapas A, Maridaki M and Koutsilieris M: Type I insulin-like growth factor receptor signaling in skeletal muscle regeneration and hypertrophy. J Musculoskelet Neuronal Interact 7: 208-218, 2007. (Pubitemid 350238147)
24. Florini JR and Ewton DZ: Highly specific inhibition of IGF-I-stimulated differentiation by an antisense oligodeoxyribonucleotide to myogenin mRNA. No effects on other actions of IGF-T. J Biol Chem 265: 13435-13437, 1990. (Pubitemid 20252185)
25. Tureckova J, Wilson EM, Cappalonga JL and Rotwein P: Insulin-like growth factor-mediated muscle differentiation: collaboration between phosphatidylinositol 3-kinase-Akt-signaling pathways and myogenin. J Biol Chem 276: 39264-39270, 2001. (Pubitemid 37371301)
26. Rommel C, Bodine SC, Clarke BA, Rossman R, Nunez L, Stitt TN, Yancopoulos GD and Glass DJ: Mediation of IGF-I-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol 3: 1009-1013, 2001.
27. Lai KM, Gonzalez M, Poueymirou WT, Kline WO, Na E, Zlotchenko E, Stitt TN, Economides AN, Yancopoulos GD and Glass DJ: Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy. Mol Cell Biol 24: 9295-9304, 2004.
28. Musaro A and Rosenthal N: The role of local insulin-like growth factor-1 isoforms in the pathophysiology of skeletal muscle. Curr Genom 3: 149-162, 2002. (Pubitemid 34568180)
29. Rosenthal SM and Cheng ZQ: Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts. Proc Natl Acad Sci USA 92: 10307-10311, 1995.
30. Hill M, Wernig A and Goldspink G: Muscle satellite (stem) cell activation during local tissue injury and repair. J Anat 203: 89-99, 2003. (Pubitemid 36889245)
31. Hill M and Goldspink G: Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage. J Physiol 549: 409-418, 2003. (Pubitemid 36701754)
32. Imanaka M, Iida K, Murawaki A, Nishizawa H, Fukuoka H, Takeno R, Takahashi Y, Okimura Y, Kaji H and Chihara K: Growth hormone stimulates mechano growth factor expression and activates myoblast transformation in C2C12 cells. Kobe J Med Sci 54: E46-54, 2008. (Pubitemid 351883934)
33. Cheema U, Brown R, Mudera V, Yang SY, McGrouther G and Goldspink G: Mechanical signals and IGF-I gene splicing in vitro in relation to development of skeletal muscle. J Cell Physiol 202: 67-75, 2005. (Pubitemid 39603363)
34. Adams GR, Haddad F and Baldwin KM: Time course of changes in markers of myogenesis in overloaded rat skeletal muscles. J Appl Physiol 87: 1705-1712, 1999.
35. Koutsilieris M; Pathophysiology of uterine leiomyomas. Biochem Cell Biol 70: 273-278, 1992.
36. Koutsilieris M, Sourla A, Pelletier G and Doillon CJ: Three-dimensional type I collagen gel system for the study of osteoblastic metastases produced by metastatic prostate cancer. J Bone Miner Res 9: 1823-1832, 1994.
37. Sourla A, Doillon C and Koutsilieris M: Three-dimensional type I collagen gel system containing MG-63 osteoblasts-like cells as a model for studying local bone reaction caused by metastatic cancer cells. Anticancer Res 16: 2773-2780, 1996. (Pubitemid 26388251)
38. Koutsilieris M, Mitsiades C and Sourla A: Insulin-like growth factor I and urokinase-type plasminogen activator bioregulation system as a survival mechanism of prostate cancer cells in osteoblastic metastases: development of anti-survival factor therapy for hormone-refractory prostate cancer. Mol Med 6: 251-267, 2000.
39. Engert JC, Berglund EB and Rosenthal N: Proliferation precedes differentiation in IGF-I-stimulated myogenesis. J Cell Biol 135: 431-440, 1996.
40. Samuel DS, Ewton DZ, Coolican SA, Petley TD, McWade FJ and Florini JR: Raf-1 activation stimulates proliferation and inhibits IGF-stimulated differentiation in L6A1 myoblasts. Horm Metab Res 31: 55-64, 1999.
41. Rommel C, Clarke BA, Zimmermann S, Nuñez L, Rossman R, Reid K, Moelling K, Yancopoulos GD and Glass DJ: Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science 286: 1738-1741, 1999. (Pubitemid 129515881)
42. McKay BR ORC, Phillips SM, Tarnopolsky MA and Parise G: Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle lengthening contractions in humans. J Physiol 586: 5549-5560, 2008.
43. Leger B, Cartoni R, Praz M, Lamon S, Dériaz O, Crettenand A, Gobelet C, Rohmer P, Konzelmann M, Luthi F and Russell AP: Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy. J Physiol 576: 923-933, 2006. (Pubitemid 44637894)
44. Haddad F and Adams GR: Selected contribution: acute cellular and molecular responses to resistance exercise. J Appl Physiol 93: 394-403, 2002. (Pubitemid 34686237)
45. Hameed M, Lange KH, Andersen JL, Schjerling P, Kjaer M, Harridge SD and Goldspink G: The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men. J Physiol 555: 231-240, 2004. (Pubitemid 38313073)
46. Bamman MM, Shipp JR, Jiang J, Gower BA, Hunter GR, Goodman A, McLafferty CL Jr and Urban RJ: Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. Am J Physiol Endocrinol Metab 280: E383-390, 2001. (Pubitemid 32466133)