Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 7, 2014, Pages

  Boardman, N T ^a   Aronsen, J M ^b,c   Louch, W E ^b,c   Sjaastad, I ^b,c   Willoch, F ^c   Christensen, G ^b,c   Sejersted, O ^b,c   Aasum, E ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Contractile efficiency; Mechanical efficiency; Mechanoenergetics; Myocardial oxygen consumption; Pressure volume area

Indexed keywords

FLUORODEOXYGLUCOSE F 18; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2; STERIPET; TAMOXIFEN; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; ENERGY COST; ENERGY EXPENDITURE; ENERGY TRANSFER; ENZYME ACTIVITY; EX VIVO STUDY; EXCITATION CONTRACTION COUPLING; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; MICROCATHETER; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PET SCANNER; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; WORK CAPACITY;

CONTRACTILE EFFICIENCY; MECHANICAL EFFICIENCY; MECHANOENERGETICS; MYOCARDIAL OXYGEN CONSUMPTION; PRESSURE-VOLUME AREA;

ANIMALS; ENERGY METABOLISM; EXCITATION CONTRACTION COUPLING; FATTY ACIDS; GENOTYPE; GLUCOSE; MICE; MICE, KNOCKOUT; MODELS, CARDIOVASCULAR; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; OXYGEN CONSUMPTION; PHENOTYPE; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TIME FACTORS; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 84900531884     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00741.2013     Document Type: Article

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