Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout

Journal of Physiology

Volumn 588, Issue 3, 2010, Pages 465-478

  Louch, William E ^a,b   Hougen, Karina ^a,b   Mørk, Halvor K ^a,b   Swift, Fredrik ^a,b   Aronsen, Jan M ^a,b   Sjaastad, Ivar ^a,b   Reims, Henrik M ^a   Roald, Borghild ^a   Andersson, Kristin B ^a,b   Christensen, Geir ^a,b   Sejersted, Ole M ^a,b  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM; CALCIUM CHANNEL L TYPE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM; ADENOSINE TRIPHOSPHATASE; CALCIUM ION; SODIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CELL ISOLATION; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; DIASTOLIC DYSFUNCTION; DISEASE COURSE; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME RELEASE; GENE DELETION; GENE DISRUPTION; HEART CONTRACTION; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; KNOCKOUT GENE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; ADULT; CATION EXCHANGE; CELL SURVIVAL; END STAGE HEART FAILURE; GENE LOSS; MUSCLE FIBER CONTRACTION; PROTEIN FUNCTION; SODIUM CELL LEVEL; SYSTOLIC DYSFUNCTION;

ANIMALS; CALCIUM; CALCIUM-TRANSPORTING ATPASES; DIASTOLE; DISEASE MODELS, ANIMAL; HEART FAILURE; MICE; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SEVERITY OF ILLNESS INDEX; SODIUM; SODIUM-CALCIUM EXCHANGER;

EID: 75649125297     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2009.183517     Document Type: Article

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