Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overload

Cardiovascular Research

Volumn 59, Issue 2, 2003, Pages 380-389

  Müller, Oliver J ^a   Lange, Mathias ^b   Rattunde, Henning ^b   Lorenzen, Hans Peter ^b   Müller, Matthias ^b   Frey, Norbert ^a   Bittner, Cordula ^b   Simonides, Warner ^c   Katus, Hugo A ^a   Franz, Wolfgang M ^d  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Ca pump; Contractile function; Gene therapy; Heart failure; SR (function)

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM; COMPLEMENTARY DNA; ISOPRENALINE;

ABDOMINAL AORTA; ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIASTOLE; FORCE; GENE EXPRESSION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HEART PAPILLARY MUSCLE; HEART RIGHT VENTRICLE; HEART VENTRICLE PRESSURE; HEART WORK; ISOLATED HEART; MEASUREMENT; MORTALITY; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PARAMETER; PRIORITY JOURNAL; PROVOCATION TEST; RAT; SARCOPLASMIC RETICULUM; SYSTOLE; TIME; TRANSGENIC ANIMAL; WILD TYPE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CALCIUM; CALCIUM-TRANSPORTING ATPASES; GENE THERAPY; GENETIC ENGINEERING; HEART FAILURE, CONGESTIVE; HOMEOSTASIS; MYOCARDIAL CONTRACTION; MYOCARDIUM; PERFUSION; RATS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES;

EID: 10744224342     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(03)00429-2     Document Type: Article

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