-
1
-
-
84860324470
-
Roles for microRNAs in conferring robustness to biological processes
-
Ebert MS, Sharp PA (2012) Roles for microRNAs in conferring robustness to biological processes. Cell 149(3):515-524.
-
(2012)
Cell
, vol.149
, Issue.3
, pp. 515-524
-
-
Ebert, M.S.1
Sharp, P.A.2
-
2
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP (2009) MicroRNAs: Target recognition and regulatory functions. Cell 136(2): 215-233.
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 215-233
-
-
Bartel, D.P.1
-
3
-
-
78650306521
-
Small RNA sorting: Matchmaking for Argonautes
-
Czech B, Hannon GJ (2011) Small RNA sorting: Matchmaking for Argonautes. Nat Rev Genet 12(1):19-31.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.1
, pp. 19-31
-
-
Czech, B.1
Hannon, G.J.2
-
4
-
-
58449134534
-
Small silencing RNAs: An expanding universe
-
Ghildiyal M, Zamore PD (2009) Small silencing RNAs: An expanding universe. Nat Rev Genet 10(2):94-108.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.2
, pp. 94-108
-
-
Ghildiyal, M.1
Zamore, P.D.2
-
5
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han J, et al. (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125(5):887-901.
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 887-901
-
-
Han, J.1
-
6
-
-
9144225636
-
The Microprocessor complex mediates the genesis of mi-croRNAs
-
Gregory RI, et al. (2004) The Microprocessor complex mediates the genesis of mi-croRNAs. Nature 432(7014):235-240.
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 235-240
-
-
Gregory, R.I.1
-
7
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ (2004) Processing of primary microRNAs by the Microprocessor complex. Nature 432(7014):231-235.
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
8
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Güttinger S, Calado A, Dahlberg JE, Kutay U (2004) Nuclear export of microRNA precursors. Science 303(5654):95-98.
-
(2004)
Science
, vol.303
, Issue.5654
, pp. 95-98
-
-
Lund, E.1
Güttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
9
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17(24):3011-3016.
-
(2003)
Genes Dev
, vol.17
, Issue.24
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
10
-
-
77955492563
-
Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases
-
Karginov FV, et al. (2010) Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases. Mol Cell 38(6):781-788.
-
(2010)
Mol Cell
, vol.38
, Issue.6
, pp. 781-788
-
-
Karginov, F.V.1
-
11
-
-
28444495985
-
Identification of novel argonaute-associated proteins
-
Meister G, et al. (2005) Identification of novel argonaute-associated proteins. Curr Biol 15(23):2149-2155.
-
(2005)
Curr Biol
, vol.15
, Issue.23
, pp. 2149-2155
-
-
Meister, G.1
-
12
-
-
77955475953
-
Expanding the microRNA targeting code: Functional sites with centered pairing
-
Shin C, et al. (2010) Expanding the microRNA targeting code: Functional sites with centered pairing. Mol Cell 38(6):789-802.
-
(2010)
Mol Cell
, vol.38
, Issue.6
, pp. 789-802
-
-
Shin, C.1
-
13
-
-
28544435974
-
Disruption of GW bodies impairs mammalian RNA interference
-
Jakymiw A, et al. (2005) Disruption of GW bodies impairs mammalian RNA interference. Nat Cell Biol 7(12):1267-1274.
-
(2005)
Nat Cell Biol
, vol.7
, Issue.12
, pp. 1267-1274
-
-
Jakymiw, A.1
-
14
-
-
28544431919
-
A role for the P-body component GW182 in microRNA function
-
Liu J, et al. (2005) A role for the P-body component GW182 in microRNA function. Nat Cell Biol 7(12):1261-1266.
-
(2005)
Nat Cell Biol
, vol.7
, Issue.12
, pp. 1261-1266
-
-
Liu, J.1
-
15
-
-
33746055678
-
MRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
-
Behm-Ansmant I, et al. (2006) mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev 20(14): 1885-1898.
-
(2006)
Genes Dev
, vol.20
, Issue.14
, pp. 1885-1898
-
-
Behm-Ansmant, I.1
-
16
-
-
0035905766
-
Role for a bidentate ribo-nuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ (2001) Role for a bidentate ribo-nuclease in the initiation step of RNA interference. Nature 409(6818):363-366.
-
(2001)
Nature
, vol.409
, Issue.6818
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
17
-
-
34249282938
-
MicroRNA silencing through RISC recruitment of eIF6
-
Chendrimada TP, et al. (2007) MicroRNA silencing through RISC recruitment of eIF6. Nature 447(7146):823-828.
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 823-828
-
-
Chendrimada, T.P.1
-
18
-
-
27144550559
-
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
-
Haase AD, et al. (2005) TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep 6(10):961-967.
-
(2005)
EMBO Rep
, vol.6
, Issue.10
, pp. 961-967
-
-
Haase, A.D.1
-
19
-
-
57049148002
-
Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs
-
Landthaler M, et al. (2008) Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs. RNA 14(12):2580-2596.
-
(2008)
RNA
, vol.14
, Issue.12
, pp. 2580-2596
-
-
Landthaler, M.1
-
20
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, et al. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425(6956):415-419.
-
(2003)
Nature
, vol.425
, Issue.6956
, pp. 415-419
-
-
Lee, Y.1
-
21
-
-
80755126865
-
Mapping a dynamic innate immunity protein interaction network regulating type i interferon production
-
Li S, Wang L, Berman M, Kong YY, Dorf ME (2011) Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity 35(3):426-440.
-
(2011)
Immunity
, vol.35
, Issue.3
, pp. 426-440
-
-
Li, S.1
Wang, L.2
Berman, M.3
Kong, Y.Y.4
Dorf, M.E.5
-
22
-
-
1642374097
-
Specificity of microRNA target selection in translational repression
-
Doench JG, Sharp PA (2004) Specificity of microRNA target selection in translational repression. Genes Dev 18(5):504-511.
-
(2004)
Genes Dev
, vol.18
, Issue.5
, pp. 504-511
-
-
Doench, J.G.1
Sharp, P.A.2
-
23
-
-
35748932681
-
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells
-
Höck J, et al. (2007) Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep 8(11):1052-1060.
-
(2007)
EMBO Rep
, vol.8
, Issue.11
, pp. 1052-1060
-
-
Höck, J.1
-
24
-
-
0036223709
-
A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles
-
Eystathioy T, et al. (2002) A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Mol Biol Cell 13(4):1338-1351.
-
(2002)
Mol Biol Cell
, vol.13
, Issue.4
, pp. 1338-1351
-
-
Eystathioy, T.1
-
25
-
-
69949117622
-
Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
-
Gibbings DJ, Ciaudo C, Erhardt M, Voinnet O (2009) Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat Cell Biol 11(9):1143-1149.
-
(2009)
Nat Cell Biol
, vol.11
, Issue.9
, pp. 1143-1149
-
-
Gibbings, D.J.1
Ciaudo, C.2
Erhardt, M.3
Voinnet, O.4
-
26
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB (2003) Prediction of mammalian microRNA targets. Cell 115(7):787-798.
-
(2003)
Cell
, vol.115
, Issue.7
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
27
-
-
58149352800
-
An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation
-
Talotta F, et al. (2009) An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation. Oncogene 28(1):73-84.
-
(2009)
Oncogene
, vol.28
, Issue.1
, pp. 73-84
-
-
Talotta, F.1
-
28
-
-
41649096450
-
Identification of let-7-regulated oncofetal genes
-
Boyerinas B, et al. (2008) Identification of let-7-regulated oncofetal genes. Cancer Res 68(8):2587-2591.
-
(2008)
Cancer Res
, vol.68
, Issue.8
, pp. 2587-2591
-
-
Boyerinas, B.1
-
29
-
-
84869237206
-
Dicer-dependent and-independent Argonaute2 protein interaction networks in mammalian cells
-
Frohn A, et al. (2012) Dicer-dependent and-independent Argonaute2 protein interaction networks in mammalian cells. Mol Cell Proteomics 11(11):1442-1456.
-
(2012)
Mol Cell Proteomics
, vol.11
, Issue.11
, pp. 1442-1456
-
-
Frohn, A.1
-
30
-
-
84860323000
-
Reduced expression of ribosomal proteins relieves microRNA-mediated repression
-
Janas MM, et al. (2012) Reduced expression of ribosomal proteins relieves microRNA-mediated repression. Mol Cell 46(2):171-186.
-
(2012)
Mol Cell
, vol.46
, Issue.2
, pp. 171-186
-
-
Janas, M.M.1
-
31
-
-
77951712353
-
HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells
-
Johnston M, Geoffroy MC, Sobala A, Hay R, Hutvagner G (2010) HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells. Mol Biol Cell 21(9):1462-1469.
-
(2010)
Mol Biol Cell
, vol.21
, Issue.9
, pp. 1462-1469
-
-
Johnston, M.1
Geoffroy, M.C.2
Sobala, A.3
Hay, R.4
Hutvagner, G.5
-
32
-
-
67651000077
-
The GW182 protein family in animal cells: New insights into domains required for miRNA-mediated gene silencing
-
Eulalio A, Tritschler F, Izaurralde E (2009) The GW182 protein family in animal cells: New insights into domains required for miRNA-mediated gene silencing. RNA 15(8): 1433-1442.
-
(2009)
RNA
, vol.15
, Issue.8
, pp. 1433-1442
-
-
Eulalio, A.1
Tritschler, F.2
Izaurralde, E.3
-
33
-
-
67649373353
-
Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway
-
Miyoshi K, Okada TN, Siomi H, Siomi MC (2009) Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway. RNA 15(7):1282-1291.
-
(2009)
RNA
, vol.15
, Issue.7
, pp. 1282-1291
-
-
Miyoshi, K.1
Okada, T.N.2
Siomi, H.3
Siomi, M.C.4
-
34
-
-
33745894330
-
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54
-
Chu CY, Rana TM (2006) Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol 4(7):e210.
-
(2006)
PLoS Biol
, vol.4
, Issue.7
-
-
Chu, C.Y.1
Rana, T.M.2
-
35
-
-
65249083468
-
Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression
-
Zipprich JT, Bhattacharyya S, Mathys H, Filipowicz W (2009) Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression. RNA 15(5):781-793.
-
(2009)
RNA
, vol.15
, Issue.5
, pp. 781-793
-
-
Zipprich, J.T.1
Bhattacharyya, S.2
Mathys, H.3
Filipowicz, W.4
-
36
-
-
79959397958
-
Genome-wide association studies of cerebral white matter lesion burden: The CHARGE consortium
-
Fornage M, et al. (2011) Genome-wide association studies of cerebral white matter lesion burden: The CHARGE consortium. Ann Neurol 69(6):928-939.
-
(2011)
Ann Neurol
, vol.69
, Issue.6
, pp. 928-939
-
-
Fornage, M.1
-
37
-
-
84867579225
-
Genetics of age-related white matter lesions from linkage to genome wide association studies
-
Freudenberger P, Schmidt R, Schmidt H (2012) Genetics of age-related white matter lesions from linkage to genome wide association studies. J Neurol Sci 322(1-2):82-86.
-
(2012)
J Neurol Sci
, vol.322
, Issue.1-2
, pp. 82-86
-
-
Freudenberger, P.1
Schmidt, R.2
Schmidt, H.3
-
38
-
-
33748752530
-
The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB
-
Albor A, et al. (2006) The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB. J Biol Chem 281(35):25850-25866.
-
(2006)
J Biol Chem
, vol.281
, Issue.35
, pp. 25850-25866
-
-
Albor, A.1
-
39
-
-
61349191567
-
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors
-
Schwamborn JC, Berezikov E, Knoblich JA (2009) The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell 136(5):913-925.
-
(2009)
Cell
, vol.136
, Issue.5
, pp. 913-925
-
-
Schwamborn, J.C.1
Berezikov, E.2
Knoblich, J.A.3
-
40
-
-
61349169058
-
Nhl-2 Modulates microRNA activity in Caenorhabditis elegans
-
Hammell CM, Lubin I, Boag PR, Blackwell TK, Ambros V (2009) nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell 136(5):926-938.
-
(2009)
Cell
, vol.136
, Issue.5
, pp. 926-938
-
-
Hammell, C.M.1
Lubin, I.2
Boag, P.R.3
Blackwell, T.K.4
Ambros, V.5
-
41
-
-
73349108109
-
The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2
-
Rybak A, et al. (2009) The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2. Nat Cell Biol 11(12):1411-1420.
-
(2009)
Nat Cell Biol
, vol.11
, Issue.12
, pp. 1411-1420
-
-
Rybak, A.1
-
42
-
-
84863329878
-
Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation
-
Chang HM, et al. (2012) Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nat Commun 3:923.
-
(2012)
Nat Commun
, vol.3
, pp. 923
-
-
Chang, H.M.1
-
43
-
-
84859873386
-
The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling
-
Chen J, Lai F, Niswander L (2012) The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev 26(8):803-815.
-
(2012)
Genes Dev
, vol.26
, Issue.8
, pp. 803-815
-
-
Chen, J.1
Lai, F.2
Niswander, L.3
-
44
-
-
84871745666
-
The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function
-
Loedige I, Gaidatzis D, Sack R, Meister G, Filipowicz W (2013) The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function. Nucleic Acids Res 41(1):518-532.
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.1
, pp. 518-532
-
-
Loedige, I.1
Gaidatzis, D.2
Sack, R.3
Meister, G.4
Filipowicz, W.5
-
45
-
-
46749129531
-
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage
-
Neumüller RA, et al. (2008) Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature 454(7201):241-245.
-
(2008)
Nature
, vol.454
, Issue.7201
, pp. 241-245
-
-
Neumüller, R.A.1
|