메뉴 건너뛰기




Volumn 9, Issue 1, 2014, Pages

Roles of PPARγ/NF-κB signaling pathway in the pathogenesis of intrahepatic cholestasis of pregnancy

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 84900465324     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087343     Document Type: Article
Times cited : (51)

References (77)
  • 3
    • 67651146698 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy
    • Geenes V, Williamson C (2009) Intrahepatic cholestasis of pregnancy. World J Gastroenterol15: 2049-2066.
    • (2009) World J Gastroenterol , vol.15 , pp. 2049-2066
    • Geenes, V.1    Williamson, C.2
  • 4
    • 84857709011 scopus 로고    scopus 로고
    • Fetal outcomes in pregnancies complicated by intrahepatic cholestasis of pregnancy in a Northern California cohort
    • Rook M, Vargas J, Caughey A, Bacchetti P, Rosenthal P, et al. (2012) Fetal outcomes in pregnancies complicated by intrahepatic cholestasis of pregnancy in a Northern California cohort. PLoS One 7: e28343.
    • (2012) PLoS One , vol.7
    • Rook, M.1    Vargas, J.2    Caughey, A.3    Bacchetti, P.4    Rosenthal, P.5
  • 5
    • 84878628235 scopus 로고    scopus 로고
    • Primary bile acids as potential biomarkers for the clinical grading of intrahepatic cholestasis of pregnancy
    • Chen J, Deng W, Wang J, Shao Y, Ou M, et al.(2013) Primary bile acids as potential biomarkers for the clinical grading of intrahepatic cholestasis of pregnancy. Int J Gynaecol Obstet 122:5-8.
    • (2013) Int J Gynaecol Obstet , vol.122 , pp. 5-8
    • Chen, J.1    Deng, W.2    Wang, J.3    Shao, Y.4    Ou, M.5
  • 7
    • 84861426857 scopus 로고    scopus 로고
    • Pay more attention to standardizing the diagnosis and treatment of intrahepatic cholestasis of pregnancy
    • Liu XH, He J (2011) Pay more attention to standardizing the diagnosis and treatment of intrahepatic cholestasis of pregnancy. Zhonghua Fu Chan Ke Za Zhi 46: 321-323.
    • (2011) Zhonghua Fu Chan Ke Za Zhi , vol.46 , pp. 321-323
    • Liu, X.H.1    He, J.2
  • 9
    • 39649093658 scopus 로고    scopus 로고
    • Sex hormones and bile acids in intrahepatic cholestasis of pregnancy
    • Reyes H (2008) Sex hormones and bile acids in intrahepatic cholestasis of pregnancy. Hepatology47: 376-379.
    • (2008) Hepatology , vol.47 , pp. 376-379
    • Reyes, H.1
  • 10
    • 84900432600 scopus 로고    scopus 로고
    • A Clinical Approach to Intrahepatic Cholestasis of Pregnancy
    • Diken Z, Usta IM, Nassar AH (2013) A Clinical Approach to Intrahepatic Cholestasis of Pregnancy. Am J Perinatol.
    • (2013) Am J Perinatol
    • Diken, Z.1    Usta, I.M.2    Nassar, A.H.3
  • 11
    • 77951224144 scopus 로고    scopus 로고
    • Immunologic abnormality of intrahepatic cholestasis of pregnancy
    • Yayi H, Danqing W, Shuyun L, Jicheng L (2010) Immunologic abnormality of intrahepatic cholestasis of pregnancy. Am J Reprod Immunol 63: 267-273.
    • (2010) Am J Reprod Immunol , vol.63 , pp. 267-273
    • Yayi, H.1    Danqing, W.2    Shuyun, L.3    Jicheng, L.4
  • 12
    • 84876288879 scopus 로고    scopus 로고
    • Expression of corticotrophin-releasing hormone and its receptor in patients with intrahepatic cholestasis of pregnancy
    • Zhou F, He MM, Liu ZF, Zhang L, Gao BX, et al. (2013) Expression of corticotrophin-releasing hormone and its receptor in patients with intrahepatic cholestasis of pregnancy. Placenta 34: 401-406.
    • (2013) Placenta , vol.34 , pp. 401-406
    • Zhou, F.1    He, M.M.2    Liu, Z.F.3    Zhang, L.4    Gao, B.X.5
  • 13
    • 77950627780 scopus 로고    scopus 로고
    • Altered gene profile of placenta from women with intrahepatic cholestasis of pregnancy
    • Wei J, Wang H, Yang X, Dong M, Wang Z (2010) Altered gene profile of placenta from women with intrahepatic cholestasis of pregnancy. Arch Gynecol Obstet 281: 801-810.
    • (2010) Arch Gynecol Obstet , vol.281 , pp. 801-810
    • Wei, J.1    Wang, H.2    Yang, X.3    Dong, M.4    Wang, Z.5
  • 14
    • 34249691640 scopus 로고    scopus 로고
    • Cell-mediated immunity imbalance in patients with intrahepatic cholestasis of pregnancy
    • Ling B, Yao F, Zhou Y, Chen Z, Shen G, et al. (2007) Cell-mediated immunity imbalance in patients with intrahepatic cholestasis of pregnancy. Cell Mol Immunol 4: 71-75.
    • (2007) Cell Mol Immunol , vol.4 , pp. 71-75
    • Ling, B.1    Yao, F.2    Zhou, Y.3    Chen, Z.4    Shen, G.5
  • 15
    • 78651062585 scopus 로고    scopus 로고
    • Longitudinal modulation of immune system cytokine profile during pregnancy
    • Denney JM, Nelson EL, Wadhwa PD, Waters TP, Mathew L, et al. (2011) Longitudinal modulation of immune system cytokine profile during pregnancy. Cytokine 53: 170-177.
    • (2011) Cytokine , vol.53 , pp. 170-177
    • Denney, J.M.1    Nelson, E.L.2    Wadhwa, P.D.3    Waters, T.P.4    Mathew, L.5
  • 16
    • 0036008785 scopus 로고    scopus 로고
    • Th1- anmd Th2-like cytokine production by first trimester decidual large granular lymphocytes is influenced by HLA-G and HLA-E
    • Rieger L, Hofmeister V, Probe C, Dietl J, Weiss EH, et al. (2002) Th1- and Th2- like cytokine production by first trimester decidual large granular lymphocytes is influenced by HLA-G and HLA-E. Mol Hum Reprod 8: 255-261. (Pubitemid 34196352)
    • (2002) Molecular Human Reproduction , vol.8 , Issue.3 , pp. 255-261
    • Rieger, L.1    Hofmeister, V.2    Probe, C.3    Dietl, J.4    Weiss, E.H.5    Steck, T.6    Kammerer, U.7
  • 17
    • 0027207375 scopus 로고
    • Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a T(H)2 phenomenon?
    • DOI 10.1016/0167-5699(93)90235-D
    • Wegmann TG, Lin H, Guilbert L, Mosmann TR (1993) Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today 14: 353-356. (Pubitemid 23198169)
    • (1993) Immunology Today , vol.14 , Issue.7 , pp. 353-356
    • Wegmann, T.G.1    Lin, H.2    Guilbert, L.3    Mosmann, T.R.4
  • 18
    • 0032227759 scopus 로고    scopus 로고
    • The changes of serum estrogen, progesterone and the function of immune system in intrahepatic cholestasis of pregnancy
    • Shi Q, Liu S, Xiong Q (1998) The changes of serum estrogen, progesterone and the function of immune system in intrahepatic cholestasis of pregnancy. Zhonghua Fu Chan Ke Za Zhi 33: 292-294.
    • (1998) Zhonghua Fu Chan Ke Za Zhi , vol.33 , pp. 292-294
    • Shi, Q.1    Liu, S.2    Xiong, Q.3
  • 19
    • 1642334209 scopus 로고    scopus 로고
    • Pregnancy-Specific Down-Regulation of NF-kappaB Expression in T Cells in Humans Is Essential for the Maintenance of the Cytokine Profile Required for Pregnancy Success
    • McCracken SA, Gallery E, Morris JM (2004) Pregnancy-specific down-regulation of NF-kappa B expression in T cells in humans is essential for the maintenance of the cytokine profile required for pregnancy success. J Immunol 172: 4583-4591. (Pubitemid 38375276)
    • (2004) Journal of Immunology , vol.172 , Issue.7 , pp. 4583-4591
    • McCracken, S.A.1    Gallery, E.2    Morris, J.M.3
  • 20
    • 79955019811 scopus 로고    scopus 로고
    • Regulated suppression of NF-κB throughout pregnancy maintains a favourable cytokine environment necessary for pregnancy success
    • Hadfield KA, McCracken SA, Ashton AW, Nguyen TG, Morris JM (2011) Regulated suppression of NF-κB throughout pregnancy maintains a favourable cytokine environment necessary for pregnancy success. J Reprod Immunol 89: 1-9.
    • (2011) J Reprod Immunol , vol.89 , pp. 1-9
    • Hadfield, K.A.1    McCracken, S.A.2    Ashton, A.W.3    Nguyen, T.G.4    Morris, J.M.5
  • 21
    • 33645947963 scopus 로고    scopus 로고
    • The pleiotropic function of PPAR gamma in the placenta
    • Schaiff WT, Barak Y, Sadovsky Y (2001) The pleiotropic function of PPAR gamma in the placenta. Mol Cell Endocrinol 249: 10-15.
    • (2001) Mol Cell Endocrinol , vol.249 , pp. 10-15
    • Schaiff, W.T.1    Barak, Y.2    Sadovsky, Y.3
  • 22
    • 33845576118 scopus 로고    scopus 로고
    • PPARs and the Placenta
    • DOI 10.1016/j.placenta.2006.04.009, PII S0143400406001202
    • Fournier T, Tsatsaris V, Handschuh K, Evain-Brion D (2007) PPARs and the placenta. Placenta 28: 65-76. (Pubitemid 44929358)
    • (2007) Placenta , vol.28 , Issue.2-3 , pp. 65-76
    • Fournier, T.1    Tsatsaris, V.2    Handschuh, K.3    Evain-Brion, D.4
  • 23
    • 84876524352 scopus 로고    scopus 로고
    • The Role of PPARs in Placental Immunology: A Systematic Review of the Literature
    • Hutter S, Knabl J, Andergassen U, Jeschke U (2013) The Role of PPARs in Placental Immunology: A Systematic Review of the Literature. PPAR Res 2013: 970276.
    • (2013) PPAR Res , vol.2013 , pp. 970276
    • Hutter, S.1    Knabl, J.2    Andergassen, U.3    Jeschke, U.4
  • 24
    • 76149092815 scopus 로고    scopus 로고
    • Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome
    • Belfort R, Berria R, Cornell J, Cusi K (2010) Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome. J Clin Endocrinol Metab 95: 829-836.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 829-836
    • Belfort, R.1    Berria, R.2    Cornell, J.3    Cusi, K.4
  • 25
    • 33644652183 scopus 로고    scopus 로고
    • Sorting out the roles of PPARalpha in energy metabolism and vascular homeostasis
    • DOI 10.1172/JCI27989
    • Lefebvre P, Chinetti G, Fruchart JC, Staels B (2006) Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J Clin Invest 116: 571-580. (Pubitemid 43326861)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 571-580
    • Lefebvre, P.1    Chinetti, G.2    Fruchart, J.-C.3    Staels, B.4
  • 26
    • 47249085629 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha activation regulates lipid metabolism in the feto-placental unit from diabetic rats
    • DOI 10.1530/REP-08-0028
    • Martínez N, Capobianco E, White V, Pustovrh MC, Higa R, et al. (2008) Peroxisome proliferator-activated receptor alpha activation regulates lipid metabolism in the feto-placental unit from diabetic rats. Reproduction 136: 95-103. (Pubitemid 351984723)
    • (2008) Reproduction , vol.136 , Issue.1 , pp. 95-103
    • Martinez, N.1    Capobianco, E.2    White, V.3    Pustovrh, M.C.4    Higa, R.5    Jawerbaum, A.6
  • 28
    • 0032484123 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging
    • DOI 10.1074/jbc.273.49.32833
    • Poynter ME, Daynes RA (1998) Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem 273: 32833-32841. (Pubitemid 28557672)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.49 , pp. 32833-32841
    • Poynter, M.E.1    Daynes, R.A.2
  • 29
    • 32944473282 scopus 로고    scopus 로고
    • Nuclear receptors in lipid metabolism: Targeting the heart of dyslipidemia
    • DOI 10.1146/annurev.med.57.121304.131428
    • Beaven SW, Tontonoz P (2006) Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia. Annu Rev Med 57: 313-329. (Pubitemid 43261994)
    • (2006) Annual Review of Medicine , vol.57 , pp. 313-329
    • Beaven, S.W.1    Tontonoz, P.2
  • 30
    • 4644269605 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptors in inflammation control
    • DOI 10.1155/S1110724304308065, PII S1110724304308065
    • Youssef J, Badr M (2004) Role of Peroxisome Proliferator-Activated Receptors in Inflammation Control. J Biomed Biotechnol 2004: 156-166. (Pubitemid 39287736)
    • (2004) Journal of Biomedicine and Biotechnology , vol.2004 , Issue.3 , pp. 156-166
    • Youssef, J.1    Badr, M.2
  • 31
    • 84876577003 scopus 로고    scopus 로고
    • Nuclear control of the inflammatory response in mammals by peroxisome proliferator-activated receptors
    • Mandard S, Patsouris D (2013) Nuclear control of the inflammatory response in mammals by peroxisome proliferator-activated receptors. PPAR Res 2013: 613864.
    • (2013) PPAR Res , vol.2013 , pp. 613864
    • Mandard, S.1    Patsouris, D.2
  • 32
    • 0036774446 scopus 로고    scopus 로고
    • 2 and troglitazone
    • DOI 10.1210/jc.2002-020613
    • Lappas M, Permezel M, Georgiou HM, Rice GE (2002) Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone. J Clin Endocrinol Metab 87: 4667-4672. (Pubitemid 35247059)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.10 , pp. 4667-4672
    • Lappas, M.1    Permezel, M.2    Georgiou, H.M.3    Rice, G.E.4
  • 36
    • 39649120375 scopus 로고    scopus 로고
    • Inhibition of adhesive interaction between multiple myeloma and bone marrow stromal cells by PPARgamma cross talk with NF-kappaB and C/EBP
    • DOI 10.1182/blood-2006-07-038026
    • Wang LH, Yang XY, Zhang X, Farrar WL (2007) Inhibition of adhesive interaction between multiple myeloma and bone marrow stromal cells by PPARgamma cross talk with NF-kappaB and C/EBP. Blood 110: 4373-4384. (Pubitemid 351377804)
    • (2007) Blood , vol.110 , Issue.13 , pp. 4373-4384
    • Li, H.W.1    Xiao, Y.Y.2    Zhang, X.3    Farrar, W.L.4
  • 38
    • 0003911029 scopus 로고    scopus 로고
    • The cytokine factsbook
    • 2nd ed. San Diego, CA: Academic Pressp
    • Fitzgerald K (2001) The cytokine factsbook, 2nd ed. The factsbook series. San Diego, CA: Academic Pressp: 515.
    • (2001) The Factsbook Series , pp. 515
    • Fitzgerald, K.1
  • 39
    • 33745470336 scopus 로고    scopus 로고
    • The Placenta Cytokine Network and Inflammatory Signals
    • DOI 10.1016/j.placenta.2005.08.009, PII S014340040500233X
    • Hauguel-de Mouzon S, Guerre-Millo M (2006) The placenta cytokine network and inflammatory signals. Placenta 27: 794-798. (Pubitemid 43947814)
    • (2006) Placenta , vol.27 , Issue.8 , pp. 794-798
    • Hauguel-De, M.S.1    Guerre-Millo, M.2
  • 40
    • 28744441914 scopus 로고    scopus 로고
    • Influence of transforming growth factor-beta2 on production of tumor necrosis factor-alpha and interferon-gamma from placenta of intrahepatic cholestasis of pregnancy
    • Ai Y, Liu SY (2004) Influence of transforming growth factor-beta2 on production of tumor necrosis factor-alpha and interferon-gamma from placenta of intrahepatic cholestasis of pregnancy. Zhonghua Fu Chan Ke Za Zhi 39: 322-325.
    • (2004) Zhonghua Fu Chan Ke Za Zhi , vol.39 , pp. 322-325
    • Ai, Y.1    Liu, S.Y.2
  • 41
    • 34447118714 scopus 로고    scopus 로고
    • The human placenta in gestational diabetes mellitus. The insulin and cytokine network
    • Desoye G, Hauguel-de Mouzon S (2011) The human placenta in gestational diabetes mellitus. The insulin and cytokine network. Diabetes Care 30: S120- S126.
    • (2011) Diabetes Care , vol.30
    • Desoye, G.1    Hauguel-de Mouzon, S.2
  • 43
    • 84863753420 scopus 로고    scopus 로고
    • Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterolsensitive activation of NF-κB
    • Aye IL, Waddell BJ, Mark PJ, Keelan JA (2012) Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterolsensitive activation of NF-κB. Mol Hum Reprod 8: 341-353.
    • (2012) Mol Hum Reprod , vol.8 , pp. 341-353
    • Aye, I.L.1    Waddell, B.J.2    Mark, P.J.3    Keelan, J.A.4
  • 45
    • 4043111379 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates
    • DOI 10.1002/hep.20336
    • Glantz A, Marschall HU, Mattsson LA (2004) Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates. Hepatology 40: 467-474. (Pubitemid 39062865)
    • (2004) Hepatology , vol.40 , Issue.2 , pp. 467-474
    • Glantz, A.1    Marschall, H.-U.2    Mattsson, L.-A.3
  • 46
    • 84859503904 scopus 로고    scopus 로고
    • A placental phenotype for intrahepatic cholestasis of pregnancy
    • Geenes VL, Lim YH, Bowman N, Tailor H, Dixon PH, et al. (2011) A placental phenotype for intrahepatic cholestasis of pregnancy. Placenta 32: 1026-1032.
    • (2011) Placenta , vol.32 , pp. 1026-1032
    • Geenes, V.L.1    Lim, Y.H.2    Bowman, N.3    Tailor, H.4    Dixon, P.H.5
  • 47
    • 84855906480 scopus 로고    scopus 로고
    • Investigation of systemic inflammatory response in first trimester pregnancy failure
    • Calleja-Agius J, Jauniaux E, Pizzey AR, Muttukrishna S (2012) Investigation of systemic inflammatory response in first trimester pregnancy failure. Hum Reprod 27: 349-357.
    • (2012) Hum Reprod , vol.27 , pp. 349-357
    • Calleja-Agius, J.1    Jauniaux, E.2    Pizzey, A.R.3    Muttukrishna, S.4
  • 48
    • 0026437754 scopus 로고
    • Immune signalling at the maternal-fetal interface and trophoblast differentiation
    • Wegmann TG, Guilbert LJ (1992) Immune signalling at the maternal-fetal interface and trophoblast differentiation. Dev Comp Immunol 16: 425-430.
    • (1992) Dev Comp Immunol , vol.16 , pp. 425-430
    • Wegmann, T.G.1    Guilbert, L.J.2
  • 49
    • 84862270948 scopus 로고    scopus 로고
    • Changes in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-D(12,14)-prostaglandin J2
    • Sykes L, MacIntyre DA, Yap XJ, Ponnampalam S, Teoh TG, et al. (2012) Changes in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-D(12,14)-prostaglandin J2. Mediators Inflamm 2012: 416739.
    • (2012) Mediators Inflamm , vol.2012 , pp. 416739
    • Sykes, L.1    MacIntyre, D.A.2    Yap, X.J.3    Ponnampalam, S.4    Teoh, T.G.5
  • 50
    • 0029905581 scopus 로고    scopus 로고
    • Regulation by anti-inflammatory cytokines (IL-4, IL-10, IL-13, TGFbeta) of interleukin-8 production by LPS- and/or TNFalpha-activated human polymorphonuclear cells
    • Marie C, Pitton C, Fitting C, Cavaillon JM (1996) Regulation by anti-inflammatory cytokines (IL-4, IL-10, IL-13, TGFbeta) of interleukin-8 production by LPS- and/or TNFalpha-activated human polymorphonuclear cells. Mediators Inflamm 5: 334-340. (Pubitemid 26395399)
    • (1996) Mediators of Inflammation , vol.5 , Issue.5 , pp. 334-340
    • Marie, C.1    Pitton, C.2    Fitting, C.3    Cavaillon, J.-M.4
  • 51
    • 0034571173 scopus 로고    scopus 로고
    • The molecular basis of T helper 1 and T helper 2 cell differentiation
    • O'Garra A, Arai N (2000) The molecular basis of T helper 1 and T helper 2 cell differentiation. Trends Cell Biol 10: 542-550.
    • (2000) Trends Cell Biol , vol.10 , pp. 542-550
    • O'Garra, A.1    Arai, N.2
  • 53
    • 80054883778 scopus 로고    scopus 로고
    • Beneficial effects of THSG on acetic acid-induced experimental colitis: Involvement of upregulation of PPAR-c and inhibition of the Nf-Kb inflammatory pathway
    • Zeng C, Xiao JH, Chang MJ, Wang JL (2011) Beneficial effects of THSG on acetic acid-induced experimental colitis: involvement of upregulation of PPAR-c and inhibition of the Nf-Kb inflammatory pathway. Molecules 16: 8552-8568.
    • (2011) Molecules , vol.16 , pp. 8552-8568
    • Zeng, C.1    Xiao, J.H.2    Chang, M.J.3    Wang, J.L.4
  • 54
    • 79959409441 scopus 로고    scopus 로고
    • Placental TNF-a signaling in illness-induced complications of pregnancy
    • Carpentier PA, Dingman AL, Palmer TD (2011) Placental TNF-a signaling in illness-induced complications of pregnancy. Am J Pathol 178: 2802-2810.
    • (2011) Am J Pathol , vol.178 , pp. 2802-2810
    • Carpentier, P.A.1    Dingman, A.L.2    Palmer, T.D.3
  • 55
    • 84900401219 scopus 로고    scopus 로고
    • Lithocholic acid-induced placental tumor necrosis factor-α upregulation and syncytiotrophoblast cell apoptosis in intrahepatic cholestasis of pregnancy
    • Du Q, Zhang Y, Pan Y, Duan T (2013) Lithocholic acid-induced placental tumor necrosis factor-α upregulation and syncytiotrophoblast cell apoptosis in intrahepatic cholestasis of pregnancy. Hepatol Res.
    • (2013) Hepatol Res
    • Du, Q.1    Zhang, Y.2    Pan, Y.3    Duan, T.4
  • 57
    • 84875225552 scopus 로고    scopus 로고
    • Homeobox genes and down-stream transcription factor PPARγ in normal and pathological human placental development
    • Murthi P, Kalionis B, Cocquebert M, Rajaraman G, Chui A, et al. (2013) Homeobox genes and down-stream transcription factor PPARγ in normal and pathological human placental development. Placenta 34: 299-309.
    • (2013) Placenta , vol.34 , pp. 299-309
    • Murthi, P.1    Kalionis, B.2    Cocquebert, M.3    Rajaraman, G.4    Chui, A.5
  • 58
    • 34547456428 scopus 로고    scopus 로고
    • Role of placentally produced inflammatory and regulatory cytokines in pregnancy and the etiology of preeclampsia
    • DOI 10.1007/s00281-007-0071-6, Immunopathology of Pregnancy and Conception
    • Rusterholz C, Hahn S, Holzgreve W (2007) Role of placentally produced inflammatory and regulatory cytokines in pregnancy and the etiology of preeclampsia. Semin Immunopathol 29: 151-162. (Pubitemid 47596394)
    • (2007) Seminars in Immunopathology , vol.29 , Issue.2 , pp. 151-162
    • Rusterholz, C.1    Hahn, S.2    Holzgreve, W.3
  • 60
    • 36949008788 scopus 로고    scopus 로고
    • PPAR Signaling in Placental Development and Function
    • Barak Y, Sadovsky Y, Shalom-Barak T (2008) PPAR Signaling in Placental Development and Function. PPAR Res 2008: 142082.
    • (2008) PPAR Res , vol.2008 , pp. 142082
    • Barak, Y.1    Sadovsky, Y.2    Shalom-Barak, T.3
  • 61
    • 38649116900 scopus 로고    scopus 로고
    • Placental implications of peroxisome proliferator-activated receptors in gestation and parturition
    • Borel V, Gallot D, Marceau G, Sapin V, Blanchon L (2008) Placental implications of peroxisome proliferator-activated receptors in gestation and parturition. PPAR Res 2008: 1-9.
    • (2008) PPAR Res , vol.2008 , pp. 1-9
    • Borel, V.1    Gallot, D.2    Marceau, G.3    Sapin, V.4    Blanchon, L.5
  • 63
    • 84867900878 scopus 로고    scopus 로고
    • Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network
    • Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, et al. (2012) Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol 372: 143-155.
    • (2012) Dev Biol , vol.372 , pp. 143-155
    • Shalom-Barak, T.1    Zhang, X.2    Chu, T.3    Timothy Schaiff, W.4    Reddy, J.K.5
  • 64
    • 77954244708 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPARgamma): Is the genomic activity the only answer?
    • Luconi M, Cantini G, Serio M (2010) Peroxisome proliferator-activated receptor gamma (PPARgamma): is the genomic activity the only answer? Steroids 75: 585-594.
    • (2010) Steroids , vol.75 , pp. 585-594
    • Luconi, M.1    Cantini, G.2    Serio, M.3
  • 65
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
    • Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W (2012) From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 45: 120-159.
    • (2012) Prog Lipid Res , vol.45 , pp. 120-159
    • Feige, J.N.1    Gelman, L.2    Michalik, L.3    Desvergne, B.4    Wahli, W.5
  • 66
    • 0033763065 scopus 로고    scopus 로고
    • Placental peroxisome proliferator-activated receptor-gamma is up-regulated by pregnancy serum
    • Waite LL, Person EC, Zhou Y, Lim KH, Scanlan TS, et al. (2000) Placental peroxisome proliferator-activated receptor-gamma is up-regulated by pregnancy serum. J Clin Endocrinol Metab 85: 3808-3814.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3808-3814
    • Waite, L.L.1    Person, E.C.2    Zhou, Y.3    Lim, K.H.4    Scanlan, T.S.5
  • 67
    • 0036144763 scopus 로고    scopus 로고
    • Regulatory functions of ubiquitination in the immune system
    • Ben-Neriah Y (2002) Regulatory functions of ubiquitination in the immune system. Nat Immunol 3: 20-26.
    • (2002) Nat Immunol , vol.3 , pp. 20-26
    • Ben-Neriah, Y.1
  • 68
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S, Karin M (2002) Missing pieces in the NF-kappaB puzzle. Cell 109: S81-S96.
    • (2002) Cell , vol.109
    • Ghosh, S.1    Karin, M.2
  • 69
    • 84900417053 scopus 로고    scopus 로고
    • Expression of NF-kappaB and COX-2 in placenta tissues of patients with intrahepatic cholestasis of pregnancy and its significance
    • Liu ZJ, Yao Q, Liu SY (2008) Expression of NF-kappaB and COX-2 in placenta tissues of patients with intrahepatic cholestasis of pregnancy and its significance. Zhonghua Fu Chan Ke Za Zhi 43: 292-294.
    • (2008) Zhonghua Fu Chan Ke Za Zhi , vol.43 , pp. 292-294
    • Liu, Z.J.1    Yao, Q.2    Liu, S.Y.3
  • 70
    • 0035992911 scopus 로고    scopus 로고
    • Nuclear factor Kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro
    • Lappas M, Permezel M, Georgiou HM, Rice GE (2002) Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro. Biol Reprod 67: 668-673. (Pubitemid 34803959)
    • (2002) Biology of Reproduction , vol.67 , Issue.2 , pp. 668-673
    • Lappas, M.1    Permezel, M.2    Georgiou, H.M.3    Rice, G.E.4
  • 71
    • 0038697896 scopus 로고    scopus 로고
    • N-Acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in Vitro
    • DOI 10.1210/jc.2002-021677
    • Lappas M, Permezel M, Rice GE (2003) N-Acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. J Clin Endocrinol Metab 88: 1723-1729. (Pubitemid 36623395)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.4 , pp. 1723-1729
    • Lappas, M.1    Permezel, M.2    Rice, G.E.3
  • 72
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • DOI 10.1038/34178
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK (1998) The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391: 79-82. (Pubitemid 28079218)
    • (1998) Nature , vol.391 , Issue.6662 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 73
    • 33646524699 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptors and inflammation
    • Moraes LA, Piqueras L, Bishop-Bailey D (2006) Peroxisome proliferatoractivated receptors and inflammation. Pharmacol Ther 110: 371-85.
    • (2006) Pharmacol Ther , vol.110 , pp. 371-385
    • Moraes, L.A.1    Piqueras, L.2    Bishop-Bailey, D.3
  • 76
    • 84873279850 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype
    • Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, Tahir M, Oduwole O, et al. (2013) Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype. Hepatology 57: 716-726.
    • (2013) Hepatology , vol.57 , pp. 716-726
    • Abu-Hayyeh, S.1    Papacleovoulou, G.2    Lövgren-Sandblom, A.3    Tahir, M.4    Oduwole, O.5
  • 77
    • 84868128717 scopus 로고    scopus 로고
    • Stereological assessment of placental morphology in intrahepatic cholestasis of pregnancy
    • Wikström Shemer E, Thorsell M, Östlund E, Blomgren B, Marschall HU (2012) Stereological assessment of placental morphology in intrahepatic cholestasis of pregnancy. Placenta 33: 914-918.
    • (2012) Placenta , vol.33 , pp. 914-918
    • Wikström Shemer, E.1    Thorsell, M.2    Östlund, E.3    Blomgren, B.4    Marschall, H.U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.