βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase rac-mediated formation of membrane protrusion and cell motility

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13638-13650

  Ma, Xiaojie ^a   Espana Serrano, Laura ^a   Kim, Wan Ju ^a   Purayil, Hamsa Thayele ^a   Nie, Zhongzhen ^a   Daaka, Yehia ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION;

ACTIN POLYMERIZATION; DEPHOSPHORYLATIONS; DOMINANT NEGATIVE; G PROTEIN COUPLED RECEPTORS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MORPHOLOGICAL CHANGES; PROTEIN EXPRESSION LEVELS; SMALL INTERFERING RNA;

PROTEINS;

BETA ARRESTIN 1; COFILIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; RAC PROTEIN;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RASGRF2 GENE; SIGNAL TRANSDUCTION; UPREGULATION;

ACTIN; ARRESTIN; CELL MIGRATION; G PROTEIN-COUPLED RECEPTORS (GPCR); GUANINE NUCLEOTIDE EXCHANGE FACTOR (GEF); PROTRUSION; RAC;

ANIMALS; ARRESTINS; CELL MEMBRANE STRUCTURES; CELL MOVEMENT; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; MICE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS;

EID: 84900462067     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.511360     Document Type: Article

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