Crimean-Congo hemorrhagic fever virus-encoded ovarian tumor protease activity is dispensable for virus RNA polymerase function

Journal of Virology

Volumn 84, Issue 1, 2010, Pages 216-226

  Bergeron, Éric ^a   Albariño, César G ^a   Khristova, Marina L ^b   Nichol, Stuart T ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROLIPOAMIDE DEHYDROGENASE; M PROTEIN; PROTEINASE; RIBAVIRIN; RNA POLYMERASE; VIRUS RNA; VITRONECTIN;

ARTICLE; BIOLOGICAL WARFARE; ENZYME ACTIVITY; NAIRO VIRUS; NUCLEOTIDE SEQUENCE; OVARY TUMOR; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PUBLIC HEALTH; RNA ANALYSIS; RNA REPLICATION; UNTRANSLATED REGION; VIRUS GENOME;

DNA-DIRECTED RNA POLYMERASES; FEMALE; GENOME, VIRAL; HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO; HUMANS; OVARIAN NEOPLASMS; PEPTIDE HYDROLASES; PROTEIN STRUCTURE, TERTIARY; RIBAVIRIN; RNA, VIRAL; VIRUS REPLICATION;

BUNYAVIRIDAE; CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS; DHORI VIRUS; NAIROVIRUS;

EID: 72849149738     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01859-09     Document Type: Article

References (45)

1. Albariño, C. G., É. Bergeron, B. R. Erickson, M. L. Khristova, P. E. Rollin, and S. T. Nichol. 2009. Efficient reverse genetics generation of infectious Junin viruses differing in glycoprotein processing. J. Virol. 83:5606-5614.
2. Altamura, L. A., A. Bertolotti-Ciarlet, J. Teigler, J. Paragas, C. S. Schmaljohn, and R. W. Doms. 2007. Identification of a novel C-terminal cleavage of Crimean-Congo hemorrhagic fever virus PreGN that leads to generation of an NSM protein. J. Virol. 81:6632-6642.
3. Andersson, I., M. Simon, A. Lundkvist, M. Nilsson, A. Holmstrom, F. Elgh, and A. Mirazimi. 2004. Role of actin filaments in targeting of Crimean Congo hemorrhagic fever virus nucleocapsid protein to perinuclear regions of mammalian cells. J. Med. Virol. 72:83-93.
4. Barr, J. N., and G. W. Wertz. 2005. Role of the conserved nucleotide mismatch within 3′- and 5′-terminal regions of Bunyamwera virus in signaling transcription. J. Virol. 79:3586-3594.
5. Biswas, S. K., and D. P. Nayak. 1994. Mutational analysis of the conserved motifs of influenza A virus polymerase basic protein 1. J. Virol. 68:1819-1826. (Pubitemid 24984068)
6. Blakqori, G., and F. Weber. 2005. Efficient cDNA-based rescue of La Crosse bunyaviruses expressing or lacking the nonstructural protein NSs. J. Virol. 79:10420-10428. (Pubitemid 41098582)
7. Deyde, V. M., M. L. Khristova, P. E. Rollin, T. G. Ksiazek, and S. T. Nichol. 2006. Crimean-Congo hemorrhagic fever virus genomics and global diversity. J. Virol. 80:8834-8842. (Pubitemid 44384893)
8. Dunn, E. F., D. C. Pritlove, H. Jin, and R. M. Elliott. 1995. Transcription of a recombinant bunyavirus RNA template by transiently expressed bunyavirus proteins. Virology 211:133-143.
9. Ebihara, H., A. Groseth, G. Neumann, Y. Kawaoka, and H. Feldmann. 2005. The role of reverse genetics systems in studying viral hemorrhagic fevers. Thromb. Haemost. 94:240-253.
10. Ergonul, O. 2006. Crimean-Congo haemorrhagic fever. Lancet Infect. Dis. 6:203-214.
11. Ergonul, O. 2008. Treatment of Crimean-Congo hemorrhagic fever. Antiviral Res. 78:125-131.
12. Fisher-Hoch, S. P., J. A. Khan, S. Rehman, S. Mirza, M. Khurshid, and J. B. McCormick. 1995. Crimean Congo-haemorrhagic fever treated with oral ribavirin. Lancet 346:472-475.
13. Flick, K., J. W. Hooper, C. S. Schmaljohn, R. F. Pettersson, H. Feldmann, and R. Flick. 2003. Rescue of Hantaan virus minigenomes. Virology 306: 219-224.
14. Flick, K., A. Katz, A. Overby, H. Feldmann, R. F. Pettersson, and R. Flick. 2004. Functional analysis of the noncoding regions of the Uukuniemi virus (Bunyaviridae) RNA segments. J. Virol. 78:11726-11738.
15. Flick, R., K. Flick, H. Feldmann, and F. Elgh. 2003. Reverse genetics for Crimean-Congo hemorrhagic fever virus. J. Virol. 77:5997-6006. (Pubitemid 36538990)
16. Flick, R., and R. F. Pettersson. 2001. Reverse genetics system for Uukuniemi virus (Bunyaviridae): RNA polymerase I-catalyzed expression of chimeric viral RNAs. J. Virol. 75:1643-1655.
17. Frías-Stäheli, N., N. V. Giannakopoulos, M. Kikkert, S. L. Taylor, A. Bridgen, J. Paragas, J. A. Richt, R. R. Rowland, C. S. Schmaljohn, D. J. Lenschow, E. J. Snijder, A. Garcia-Sastre, and H. W. Virgin IV. 2007. Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses. Cell Host Microbe 2:404-416. (Pubitemid 350225347)
18. Gerrard, S. R., B. H. Bird, C. G. Albarino, and S. T. Nichol. 2007. The NSm proteins of Rift Valley fever virus are dispensable for maturation, replication and infection. Virology 359:459-465.
19. Habjan, M., N. Penski, M. Spiegel, and F. Weber. 2008. T7 RNA polymerase- dependent and -independent systems for cDNA-based rescue of Rift Valley fever virus. J. Gen. Virol. 89:2157-2166.
20. Hass, M., U. Golnitz, S. Muller, B. Becker-Ziaja, and S. Gunther. 2004. Replicon system for Lassa virus. J. Virol. 78:13793-13803.
21. Honig, J. E., J. C. Osborne, and S. T. Nichol. 2004. Crimean-Congo hemorrhagic fever virus genome L RNA segment and encoded protein. Virology 321:29-35. (Pubitemid 38368100)
22. Hoogstraal, H. 1979. The epidemiology of tick-borne Crimean-Congo hemorrhagic fever in Asia, Europe, and Africa. J. Med. Entomol. 15:307-417.
23. Ikegami, T., S. Won, C. J. Peters, and S. Makino. 2006. Rescue of infectious Rift Valley fever virus entirely from cDNA, analysis of virus lacking the NSs gene, and expression of a foreign gene. J. Virol. 80:2933-2940. (Pubitemid 43346388)
24. Jin, H., and R. M. Elliott. 1992. Mutagenesis of the L protein encoded by Bunyamwera virus and production of monospecific antibodies. J. Gen. Virol. 73:2235-2244.
25. Kattenhorn, L. M., G. A. Korbel, B. M. Kessler, E. Spooner, and H. L. Ploegh. 2005. A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae. Mol. Cell 19:547-557.
26. Kentsis, A., I. Topisirovic, B. Culjkovic, L. Shao, and K. L. Borden. 2004. Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap. Proc. Natl. Acad. Sci. U. S. A. 101:18105-18110.
27. Kinsella, E., S. G. Martin, A. Grolla, M. Czub, H. Feldmann, and R. Flick. 2004. Sequence determination of the Crimean-Congo hemorrhagic fever virus L segment. Virology 321:23-28. (Pubitemid 38368099)
28. Kohl, A., E. F. Dunn, A. C. Lowen, and R. M. Elliott. 2004. Complementarity, sequence and structural elements within the 3′ and 5′ non-coding regions of the Bunyamwera orthobunyavirus S segment determine promoter strength. J. Gen. Virol. 85:3269-3278.
29. Kohl, A., A. C. Lowen, V. H. Leonard, and R. M. Elliott. 2006. Genetic elements regulating packaging of the Bunyamwera orthobunyavirus genome. J. Gen. Virol. 87:177-187.
30. Lopez, N., R. Muller, C. Prehaud, and M. Bouloy. 1995. The L protein of Rift Valley fever virus can rescue viral ribonucleoproteins and transcribe synthetic genome-like RNA molecules. J. Virol. 69:3972-3979.
31. Love, K. R., A. Catic, C. Schlieker, and H. L. Ploegh. 2007. Mechanisms, biology and inhibitors of deubiquitinating enzymes. Nat. Chem. Biol. 3:697-705.
32. Lowen, A. C., C. Noonan, A. McLees, and R. M. Elliott. 2004. Efficient bunyavirus rescue from cloned cDNA. Virology 330:493-500.
33. Marriott, A. C., A. A. el-Ghorr, and P. A. Nuttall. 1992. Dugbe Nairovirus M RNA: nucleotide sequence and coding strategy. Virology 190:606-615.
34. Marriott, A. C., and P. A. Nuttall. 1996. Large RNA segment of Dugbe nairovirus encodes the putative RNA polymerase. J. Gen. Virol. 77:1775-1780.
35. Miyazaki, J., S. Takaki, K. Araki, F. Tashiro, A. Tominaga, K. Takatsu, and K. Yamamura. 1989. Expression vector system based on the chicken beta-actin promoter directs efficient production of interleukin-5. Gene 79:269-277. (Pubitemid 19183206)
36. Neumann, G., and Y. Kawaoka. 2004. Reverse genetics systems for the generation of segmented negative-sense RNA viruses entirely from cloned cDNA. Curr. Top. Microbiol. Immunol. 283:43-60.
37. Ogawa, Y., K. Sugiura, K. Kato, Y. Tohya, and H. Akashi. 2007. Rescue of Akabane virus (family Bunyaviridae) entirely from cloned cDNAs by using RNA polymerase I. J. Gen. Virol. 88:3385-3390.
38. Paragas, J., C. A. Whitehouse, T. P. Endy, and M. Bray. 2004. A simple assay for determining antiviral activity against Crimean-Congo hemorrhagic fever virus. Antiviral Res. 62:21-25. (Pubitemid 38340744)
39. Parker, W. B. 2005. Metabolism and antiviral activity of ribavirin. Virus Res. 107:165-171.
40. Pekosz, A., B. He, and R. A. Lamb. 1999. Reverse genetics of negativestrand RNA viruses: closing the circle. Proc. Natl. Acad. Sci. U. S. A. 96:8804-8806.
41. Sanchez, A. J., M. J. Vincent, and S. T. Nichol. 2002. Characterization of the glycoproteins of Crimean-Congo hemorrhagic fever virus. J. Virol. 76:7263-7275.
42. Tignor, G. H., and C. A. Hanham. 1993. Ribavirin efficacy in an in vivo model of Crimean-Congo hemorrhagic fever virus (CCHF) infection. Antiviral Res. 22:309-325. (Pubitemid 23340819)
43. Watts, D. M., M. A. Ussery, D. Nash, and C. J. Peters. 1989. Inhibition of Crimean-Congo hemorrhagic fever viral infectivity yields in vitro by ribavirin. Am. J. Trop. Med. Hyg. 41:581-585.
44. Zhang, Y., X. H. Li, H. Jiang, C. X. Huang, P. Z. Wang, D. L. Mou, L. Sun, Z. Xu, X. Wei, and X. F. Bai. 2008. Expression of L protein of Hantaan virus 84FLi strain and its application for recovery of minigenomes. APMIS 116: 1089-1096.
45. Ziebuhr, J., E. J. Snijder, and A. E. Gorbalenya. 2000. Virus-encoded proteinases and proteolytic processing in the Nidovirales. J. Gen. Virol. 81:853-879.