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Volumn 369, Issue 1645, 2014, Pages

Human genetics of tuberculosis: A long and winding road

Author keywords

Complex genetic predisposition; Genetic variant; Latent tuberculosis infection; Mendelian predisposition; Primary tuberculosis; Pulmonary tuberculosis

Indexed keywords

AGE; BACTERIAL DISEASE; GENETIC VARIATION; IMMUNITY; PATHOGEN; POPULATION GENETICS; TUBERCULOSIS;

EID: 84900330164     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2013.0428     Document Type: Review
Times cited : (153)

References (127)
  • 1
    • 84893257773 scopus 로고    scopus 로고
    • WHO, Geneva, Switzerland: World Health Organization
    • WHO. 2013 Global tuberculosis report. Geneva, Switzerland: World Health Organization.
    • (2013) Global tuberculosis report
  • 2
    • 1842561506 scopus 로고    scopus 로고
    • Tuberculosis: A problem with persistence
    • (doi:10.1038/nrmicro749)
    • Stewart GR, Robertson BD, Young DB. 2003 Tuberculosis: a problem with persistence. Nat. Rev. Microbiol. 1, 97-105. (doi:10.1038/nrmicro749)
    • (2003) Nat. Rev. Microbiol. , vol.1 , pp. 97-105
    • Stewart, G.R.1    Robertson, B.D.2    Young, D.B.3
  • 4
    • 34250025942 scopus 로고    scopus 로고
    • Clinical manifestations of tuberculosis in children
    • (doi:10.1016/j.prrv.2007.04.008)
    • Cruz AT, Starke JR. 2007 Clinical manifestations of tuberculosis in children. Paediatr. Respir. Rev. 8, 107-117. (doi:10.1016/j.prrv.2007.04.008)
    • (2007) Paediatr. Respir. Rev. , vol.8 , pp. 107-117
    • Cruz, A.T.1    Starke, J.R.2
  • 6
    • 84864357703 scopus 로고    scopus 로고
    • The immunological life cycle of tuberculosis
    • (doi:10.1038/nri3259)
    • Ernst JD. 2012 The immunological life cycle of tuberculosis. Nat. Rev. Immunol. 12, 581-591. (doi:10.1038/nri3259)
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 581-591
    • Ernst, J.D.1
  • 8
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: The human model
    • (doi:10.1146/ annurev.immunol.20.081501.125851)
    • Casanova JL, Abel L. 2002 Genetic dissection of immunity to mycobacteria: the human model. Annu. Rev. Immunol. 20, 581-620. (doi:10.1146/ annurev.immunol.20.081501.125851)
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 581-620
    • Casanova, J.L.1    Abel, L.2
  • 11
    • 0001345951 scopus 로고
    • Twin studies on the significance of genetic factors in tuberculosis
    • Kallmann FJ, Reisner D. 1943 Twin studies on the significance of genetic factors in tuberculosis. Am. Rev. Tuberc. 47, 549-574.
    • (1943) Am. Rev. Tuberc. , vol.47 , pp. 549-574
    • Kallmann, F.J.1    Reisner, D.2
  • 12
    • 0030894776 scopus 로고    scopus 로고
    • The origin and erratic global spread of tuberculosis. How the past explains the present and is the key to the future
    • (doi:10.1016/S0272-5231(05) 70356-7)
    • Stead WW. 1997 The origin and erratic global spread of tuberculosis. How the past explains the present and is the key to the future. Clin. Chest Med. 18, 65-77. (doi:10.1016/S0272-5231(05) 70356-7)
    • (1997) Clin. Chest Med. , vol.18 , pp. 65-77
    • Stead, W.W.1
  • 13
    • 0027065581 scopus 로고
    • Genetics and resistance to tuberculosis. Could resistance be enhanced by genetic engineering?
    • (doi:10.7326/0003-4819-116-11-937)
    • Stead WW. 1992 Genetics and resistance to tuberculosis. Could resistance be enhanced by genetic engineering? Ann. Intern. Med. 116, 937-941. (doi:10.7326/0003-4819-116-11-937)
    • (1992) Ann. Intern. Med. , vol.116 , pp. 937-941
    • Stead, W.W.1
  • 14
    • 0025017582 scopus 로고
    • Racial differences in susceptibility to infection by Mycobacterium tuberculosis
    • (doi:10.1056/ NEJM199002153220702)
    • Stead WW, Senner JW, Reddick WT, Lofgren JP. 1990 Racial differences in susceptibility to infection by Mycobacterium tuberculosis. N. Engl. J. Med. 322, 422-427. (doi:10.1056/ NEJM199002153220702)
    • (1990) N. Engl. J. Med. , vol.322 , pp. 422-427
    • Stead, W.W.1    Senner, J.W.2    Reddick, W.T.3    Lofgren, J.P.4
  • 15
    • 30344444285 scopus 로고    scopus 로고
    • Mouse models for the genetic study of tuberculosis susceptibility
    • (doi:10. 1093/bfgp/4.3.277)
    • Di Pietrantonio T, Schurr E. 2005 Mouse models for the genetic study of tuberculosis susceptibility. Brief Funct. Genomics Proteomics 4, 277-292. (doi:10. 1093/bfgp/4.3.277)
    • (2005) Brief Funct. Genomics Proteomics , vol.4 , pp. 277-292
    • Di Pietrantonio, T.1    Schurr, E.2
  • 16
    • 38449083851 scopus 로고    scopus 로고
    • Host genetics of mycobacterial diseases in mice and men: Forward genetic studies of BCG-osis and tuberculosis
    • (doi:10.1146/annurev.genom.8.080706.092315)
    • Fortin A, Abel L, Casanova JL, Gros P. 2007 Host genetics of mycobacterial diseases in mice and men: forward genetic studies of BCG-osis and tuberculosis. Annu. Rev. Genomics Hum. Genet. 8, 163-192. (doi:10.1146/annurev.genom.8.080706.092315)
    • (2007) Annu. Rev. Genomics Hum. Genet. , vol.8 , pp. 163-192
    • Fortin, A.1    Abel, L.2    Casanova, J.L.3    Gros, P.4
  • 17
    • 0027262167 scopus 로고
    • Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg
    • (doi:10.1016/0092-8674(93) 90135-D)
    • Vidal SM, Malo D, Vogan K, Skamene E, Gros P. 1993 Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg. Cell 73, 469-485. (doi:10.1016/0092-8674(93) 90135-D)
    • (1993) Cell , vol.73 , pp. 469-485
    • Vidal, S.M.1    Malo, D.2    Vogan, K.3    Skamene, E.4    Gros, P.5
  • 18
    • 67650932256 scopus 로고    scopus 로고
    • Cell-mediated immune responses in tuberculosis
    • (doi:10.1146/annurev.immunol.021908.132703)
    • Cooper AM. 2009 Cell-mediated immune responses in tuberculosis. Annu. Rev. Immunol. 27, 393-422. (doi:10.1146/annurev.immunol.021908.132703)
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 393-422
    • Cooper, A.M.1
  • 19
    • 2542480887 scopus 로고    scopus 로고
    • Immunity to tuberculosis
    • (doi:10.1146/ annurev.immunol.22.012703.104635)
    • North RJ, Jung YJ. 2004 Immunity to tuberculosis. Annu. Rev. Immunol. 22, 599-623. (doi:10.1146/ annurev.immunol.22.012703.104635)
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 599-623
    • North, R.J.1    Jung, Y.J.2
  • 20
    • 68149171688 scopus 로고    scopus 로고
    • T cells in mycobacterial infection and disease
    • (doi:10.1016/j.coi.2009.06.004)
    • Cooper AM. 2009 T cells in mycobacterial infection and disease. Curr. Opin. Immunol. 21, 378-384. (doi:10.1016/j.coi.2009.06.004)
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 378-384
    • Cooper, A.M.1
  • 21
    • 84864447925 scopus 로고    scopus 로고
    • Antiretroviral therapy for prevention of tuberculosis in adults with HIV: A systematic review and meta-analysis
    • (doi:10.1371/journal.pmed.1001270)
    • Suthar AB et al. 2012 Antiretroviral therapy for prevention of tuberculosis in adults with HIV: a systematic review and meta-analysis. PLoS Med. 9, e1001270. (doi:10.1371/journal.pmed.1001270)
    • (2012) PLoS Med. , vol.9
    • Suthar, A.B.1
  • 23
    • 29144484290 scopus 로고    scopus 로고
    • Tuberculosis in children and adults: Two distinct genetic diseases
    • (doi:10.1084/jem.20052302)
    • Alcais A, Fieschi C, Abel L, Casanova JL. 2005 Tuberculosis in children and adults: two distinct genetic diseases. J. Exp. Med. 202, 1617-1621. (doi:10.1084/jem.20052302)
    • (2005) J. Exp. Med. , vol.202 , pp. 1617-1621
    • Alcais, A.1    Fieschi, C.2    Abel, L.3    Casanova, J.L.4
  • 24
    • 79954588322 scopus 로고    scopus 로고
    • IL-12Rbeta1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey
    • (doi:10.1371/journal.pone.0018524)
    • Boisson-Dupuis S et al. 2011 IL-12Rbeta1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey. PLoS ONE 6, e18524. (doi:10.1371/journal.pone.0018524)
    • (2011) PLoS ONE , vol.6
    • Boisson-Dupuis, S.1
  • 25
    • 0018557887 scopus 로고
    • Tuberculin skin testing. The state of the art
    • (doi:10.1378/ chest.76.6.764)
    • Reichman LB. 1979 Tuberculin skin testing. The state of the art. Chest 76, 764-770. (doi:10.1378/ chest.76.6.764)
    • (1979) Chest , vol.76 , pp. 764-770
    • Reichman, L.B.1
  • 26
    • 33749447565 scopus 로고    scopus 로고
    • An update on the diagnosis of tuberculosis infection
    • (doi:10.1164/rccm.200509-1516PP)
    • Richeldi L. 2006 An update on the diagnosis of tuberculosis infection. Am. J. Respir. Crit. Care Med. 174, 736-742. (doi:10.1164/rccm.200509-1516PP)
    • (2006) Am. J. Respir. Crit. Care Med. , vol.174 , pp. 736-742
    • Richeldi, L.1
  • 27
    • 77951831599 scopus 로고    scopus 로고
    • Tuberculin skin test and in vitro assays provide complementary measures of antimycobacterial immunity in children and adolescents
    • (doi:10.1378/ chest.09-1852)
    • Gallant CJ et al. 2010 Tuberculin skin test and in vitro assays provide complementary measures of antimycobacterial immunity in children and adolescents. Chest 137, 1071-1077. (doi:10.1378/ chest.09-1852)
    • (2010) Chest , vol.137 , pp. 1071-1077
    • Gallant, C.J.1
  • 28
  • 30
    • 0034999250 scopus 로고    scopus 로고
    • Genetic regulation of acquired immune responses to antigens of Mycobacterium tuberculosis: A study of twins in West Africa
    • (doi:10.1128/IAI.69.6.3989-3994.2001)
    • Jepson A, Fowler A, Banya W, Singh M, Bennett S, Whittle H, Hill AV. 2001 Genetic regulation of acquired immune responses to antigens of Mycobacterium tuberculosis: a study of twins in West Africa. Infect. Immun. 69, 3989-3994. (doi:10.1128/IAI.69.6.3989-3994.2001)
    • (2001) Infect. Immun. , vol.69 , pp. 3989-3994
    • Jepson, A.1    Fowler, A.2    Banya, W.3    Singh, M.4    Bennett, S.5    Whittle, H.6    Hill, A.V.7
  • 32
    • 71949094124 scopus 로고    scopus 로고
    • High heritability of antimycobacterial immunity in an area of hyperendemicity for tuberculosis disease
    • (doi:10.1086/648611)
    • Cobat A et al. 2010 High heritability of antimycobacterial immunity in an area of hyperendemicity for tuberculosis disease. J. Infect Dis. 201, 15-19. (doi:10.1086/648611)
    • (2010) J. Infect Dis. , vol.201 , pp. 15-19
    • Cobat, A.1
  • 33
    • 84858136544 scopus 로고    scopus 로고
    • Tuberculin skin test reactivity is dependent on host genetic background in Colombian tuberculosis household contacts
    • (doi:10. 1093/cid/cir972)
    • Cobat A, Barrera LF, Henao H, Arbelaez P, Abel L, Garcia LF, Schurr E, Alcais A. 2012 Tuberculin skin test reactivity is dependent on host genetic background in Colombian tuberculosis household contacts. Clin. Infect. Dis. 54, 968-971. (doi:10. 1093/cid/cir972)
    • (2012) Clin. Infect. Dis. , vol.54 , pp. 968-971
    • Cobat, A.1    Barrera, L.F.2    Henao, H.3    Arbelaez, P.4    Abel, L.5    Garcia, L.F.6    Schurr, E.7    Alcais, A.8
  • 35
    • 84880617250 scopus 로고    scopus 로고
    • Genetic and shared environmental influences on interferon-gamma production in response to Mycobacterium tuberculosis antigens in a Ugandan population
    • (doi:10.4269/ajtmh.12-0670)
    • Tao L, Zalwango S, Chervenak K, Thiel B, Malone LL, Qiu F, Mayanja-Kizza H, Boom WH, Stein CM. 2013 Genetic and shared environmental influences on interferon-gamma production in response to Mycobacterium tuberculosis antigens in a Ugandan population. Am. J. Trop. Med. Hyg. 89, 169-173. (doi:10.4269/ajtmh.12-0670)
    • (2013) Am. J. Trop. Med. Hyg. , vol.89 , pp. 169-173
    • Tao, L.1    Zalwango, S.2    Chervenak, K.3    Thiel, B.4    Malone, L.L.5    Qiu, F.6    Mayanja-Kizza, H.7    Boom, W.H.8    Stein, C.M.9
  • 36
    • 65549083803 scopus 로고    scopus 로고
    • IL10 haplotype associated with tuberculin skin test response but not with pulmonary TB
    • (doi:10.1371/ journal.pone.0005420)
    • Thye T et al. 2009 IL10 haplotype associated with tuberculin skin test response but not with pulmonary TB. PLoS ONE 4, e5420. (doi:10.1371/ journal.pone.0005420)
    • (2009) PLoS ONE , vol.4
    • Thye, T.1
  • 37
    • 75149120083 scopus 로고    scopus 로고
    • Cytokine genes are associated with tuberculin skin test response in a native Brazilian population
    • Edinb, (doi:10.1016/j. tube.2009.11.002)
    • Zembrzuski VM, Basta PC, Callegari-Jacques SM, Santos RV, Coimbra CE, Salzano FM, Hutz MH. 2010 Cytokine genes are associated with tuberculin skin test response in a native Brazilian population. Tuberculosis (Edinb) 90, 44-49. (doi:10.1016/j. tube.2009.11.002)
    • (2010) Tuberculosis , vol.90 , pp. 44-49
    • Zembrzuski, V.M.1    Basta, P.C.2    Callegari-Jacques, S.M.3    Santos, R.V.4    Coimbra, C.E.5    Salzano, F.M.6    Hutz, M.H.7
  • 38
    • 58149354501 scopus 로고    scopus 로고
    • Genome scan of M. tuberculosis infection and disease in Ugandans
    • (doi:10.1371/journal.pone.0004094)
    • Stein CM et al. 2008 Genome scan of M. tuberculosis infection and disease in Ugandans. PLoS ONE 3, e4094. (doi:10.1371/journal.pone.0004094)
    • (2008) PLoS ONE , vol.3
    • Stein, C.M.1
  • 39
    • 73349135673 scopus 로고    scopus 로고
    • Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis
    • (doi:10. 1084/jem.20090892)
    • Cobat A et al. 2009 Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis. J. Exp. Med. 206, 2583-2591. (doi:10. 1084/jem.20090892)
    • (2009) J. Exp. Med. , vol.206 , pp. 2583-2591
    • Cobat, A.1
  • 40
    • 84884378812 scopus 로고    scopus 로고
    • Identification of a major locus, TNF1, that controls BCG-triggered tumor necrosis factor production by leukocytes in an area hyperendemic for tuberculosis
    • (doi:10.1093/cid/cit438)
    • Cobat A et al. 2013 Identification of a major locus, TNF1, that controls BCG-triggered tumor necrosis factor production by leukocytes in an area hyperendemic for tuberculosis. Clin. Infect. Dis. 57, 963-970. (doi:10.1093/cid/cit438)
    • (2013) Clin. Infect. Dis. , vol.57 , pp. 963-970
    • Cobat, A.1
  • 41
    • 29144459487 scopus 로고
    • Diagnose und epidemiologie des lungentuberculose des kindes
    • Ranke KE. 1910 Diagnose und epidemiologie des lungentuberculose des kindes. Arch. Kinderheilkd 54, 279-306.
    • (1910) Arch. Kinderheilkd , vol.54 , pp. 279-306
    • Ranke, K.E.1
  • 42
    • 36849092820 scopus 로고    scopus 로고
    • Tuberculosis
    • (doi:10.1016/S0140-6736(07) 61262-8)
    • Maartens G, Wilkinson RJ. 2007 Tuberculosis. Lancet 370, 2030-2043. (doi:10.1016/S0140-6736(07) 61262-8)
    • (2007) Lancet , vol.370 , pp. 2030-2043
    • Maartens, G.1    Wilkinson, R.J.2
  • 43
    • 79955103273 scopus 로고    scopus 로고
    • WHO, Geneva, Switzerland: WHO/HTM/TB/2011
    • WHO. 2011 Global tuberculosis control. Geneva, Switzerland: WHO/HTM/TB/2011.
    • (2011) Global tuberculosis control
  • 45
    • 34250875069 scopus 로고    scopus 로고
    • BCG-osis and tuberculosis in a child with chronic granulomatous disease
    • (doi:10.1016/ j.jaci.2007.04.034)
    • Bustamante J et al. 2007 BCG-osis and tuberculosis in a child with chronic granulomatous disease. J. Allergy Clin. Immunol. 120, 32-38. (doi:10.1016/ j.jaci.2007.04.034)
    • (2007) J. Allergy Clin. Immunol. , vol.120 , pp. 32-38
    • Bustamante, J.1
  • 46
    • 0031914824 scopus 로고    scopus 로고
    • The role of phagocytic respiratory burst in host defense against Mycobacterium tuberculosis
    • (doi:10.1086/517036)
    • Lau YL, Chan GC, Ha SY, Hui YF, Yuen KY. 1998 The role of phagocytic respiratory burst in host defense against Mycobacterium tuberculosis. Clin. Infect. Dis. 26, 226-227. (doi:10.1086/517036)
    • (1998) Clin. Infect. Dis. , vol.26 , pp. 226-227
    • Lau, Y.L.1    Chan, G.C.2    Ha, S.Y.3    Hui, Y.F.4    Yuen, K.Y.5
  • 47
    • 44949109341 scopus 로고    scopus 로고
    • Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease: A review of 17 patients living in a region endemic for tuberculosis
    • (doi:10.1097/INF. 0b013e31815b494c)
    • Lee PP et al. 2008 Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease: a review of 17 patients living in a region endemic for tuberculosis. Pediatr. Infect Dis. J 27, 224-230. (doi:10.1097/INF. 0b013e31815b494c)
    • (2008) Pediatr. Infect Dis. J , vol.27 , pp. 224-230
    • Lee, P.P.1
  • 48
    • 37849008955 scopus 로고    scopus 로고
    • Clinical features, long-term follow-up and outcome of a large cohort of patients with Chronic Granulomatous Disease: An Italian multicenter study
    • (doi:10.1016/j.clim.2007.09.008)
    • Martire B et al. 2008 Clinical features, long-term follow-up and outcome of a large cohort of patients with Chronic Granulomatous Disease: an Italian multicenter study. Clin. Immunol. 126, 155-164. (doi:10.1016/j.clim.2007.09.008)
    • (2008) Clin. Immunol. , vol.126 , pp. 155-164
    • Martire, B.1
  • 49
    • 3042675144 scopus 로고    scopus 로고
    • Chronic granulomatous disease: A clinical survey of 41 patients from the Iranian primary immunodeficiency registry
    • (doi:10.1159/ 000078774)
    • Movahedi M et al. 2004 Chronic granulomatous disease: a clinical survey of 41 patients from the Iranian primary immunodeficiency registry. Int. Arch. Allergy Immunol. 134, 253-259. (doi:10.1159/ 000078774)
    • (2004) Int. Arch. Allergy Immunol. , vol.134 , pp. 253-259
    • Movahedi, M.1
  • 51
    • 57149144518 scopus 로고    scopus 로고
    • The genetic heterogeneity of Mendelian susceptibility to mycobacterial diseases
    • quiz 1052-1043, (doi:10.1016/j. jaci.2008.10.037)
    • Al-Muhsen S, Casanova JL. 2008 The genetic heterogeneity of Mendelian susceptibility to mycobacterial diseases. J. Allergy Clin. Immunol. 122, 1043-1051; quiz 1052-1043. (doi:10.1016/j. jaci.2008.10.037)
    • (2008) J. Allergy Clin. Immunol. , vol.122 , pp. 1043-1051
    • Al-Muhsen, S.1    Casanova, J.L.2
  • 52
    • 84866748115 scopus 로고    scopus 로고
    • Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency
    • (doi:10.1126/science.1224026)
    • Bogunovic D et al. 2012 Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency. Science 337, 1684-1688. (doi:10.1126/science.1224026)
    • (2012) Science , vol.337 , pp. 1684-1688
    • Bogunovic, D.1
  • 53
    • 79951647077 scopus 로고    scopus 로고
    • Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease
    • (doi:10.1038/ni.1992)
    • Bustamante J et al. 2011 Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nat. Immunol. 12, 213-221. (doi:10.1038/ni.1992)
    • (2011) Nat. Immunol. , vol.12 , pp. 213-221
    • Bustamante, J.1
  • 54
    • 33749600724 scopus 로고    scopus 로고
    • Inborn errors of IL-12/ 23-and IFN-gamma-mediated immunity: Molecular, cellular, and clinical features
    • (doi:10.1016/j.smim.2006. 07.010)
    • Filipe-Santos O et al. 2006 Inborn errors of IL-12/ 23-and IFN-gamma-mediated immunity: molecular, cellular, and clinical features. Semin. Immunol. 18, 347-361. (doi:10.1016/j.smim.2006. 07.010)
    • (2006) Semin. Immunol. , vol.18 , pp. 347-361
    • Filipe-Santos, O.1
  • 55
    • 79960219807 scopus 로고    scopus 로고
    • IRF8 mutations and human dendritic-cell immunodeficiency
    • (doi:10.1056/NEJMoa1100066)
    • Hambleton S et al. 2011 IRF8 mutations and human dendritic-cell immunodeficiency. N. Engl. J. Med. 365, 127-138. (doi:10.1056/NEJMoa1100066)
    • (2011) N. Engl. J. Med. , vol.365 , pp. 127-138
    • Hambleton, S.1
  • 56
    • 84884310169 scopus 로고    scopus 로고
    • The genetic theory of infectious diseases: A brief history and selected illustrations
    • (doi:10.1146/annurev-genom-091212-153448)
    • Casanova JL, Abel L. 2013 The genetic theory of infectious diseases: a brief history and selected illustrations. Annu. Rev. Genomics Hum. Genet. 14, 215-243. (doi:10.1146/annurev-genom-091212-153448)
    • (2013) Annu. Rev. Genomics Hum. Genet. , vol.14 , pp. 215-243
    • Casanova, J.L.1    Abel, L.2
  • 57
    • 4344648175 scopus 로고    scopus 로고
    • Clinical features of dominant and recessive interferon gamma receptor 1 deficiencies
    • (doi:10.1016/S0140-6736(04) 17552-1)
    • Dorman SE et al. 2004 Clinical features of dominant and recessive interferon gamma receptor 1 deficiencies. Lancet 364, 2113-2121. (doi:10.1016/S0140-6736(04) 17552-1)
    • (2004) Lancet , vol.364 , pp. 2113-2121
    • Dorman, S.E.1
  • 58
    • 0036498619 scopus 로고    scopus 로고
    • Genetic basis of patients with bacille Calmette-Guerin osteomyelitis in Japan: Identification of dominant partial interferon-gamma receptor 1 deficiency as a predominant type
    • (doi:10.1086/339011)
    • Sasaki Y, Nomura A, Kusuhara K, Takada H, Ahmed S, Obinata K, Hamada K, Okimoto Y, Hara T. 2002 Genetic basis of patients with bacille Calmette-Guerin osteomyelitis in Japan: identification of dominant partial interferon-gamma receptor 1 deficiency as a predominant type. J. Infect Dis. 185, 706-709. (doi:10.1086/339011)
    • (2002) J. Infect Dis. , vol.185 , pp. 706-709
    • Sasaki, Y.1    Nomura, A.2    Kusuhara, K.3    Takada, H.4    Ahmed, S.5    Obinata, K.6    Hamada, K.7    Okimoto, Y.8    Hara, T.9
  • 59
    • 0036158322 scopus 로고    scopus 로고
    • Inherited interleukin-12 deficiency: IL12B genotype and clinical phenotype of 13 patients from six kindreds
    • (doi:10.1086/338625)
    • Picard C et al. 2002 Inherited interleukin-12 deficiency: IL12B genotype and clinical phenotype of 13 patients from six kindreds. Am. J. Hum. Genet. 70, 336-348. (doi:10.1086/338625)
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 336-348
    • Picard, C.1
  • 60
    • 0031468410 scopus 로고    scopus 로고
    • Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis
    • (doi:10.1172/JCI119810)
    • Jouanguy E et al. 1997 Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis. J. Clin. Invest. 100, 2658-2664. (doi:10.1172/JCI119810)
    • (1997) J. Clin. Invest. , vol.100 , pp. 2658-2664
    • Jouanguy, E.1
  • 61
    • 78649351360 scopus 로고    scopus 로고
    • Revisiting human IL-12Rbeta1 deficiency: A survey of 141 patients from 30 countries
    • (doi:10.1097/MD.0b013e3181fdd832)
    • de Beaucoudrey L et al. 2010 Revisiting human IL-12Rbeta1 deficiency: a survey of 141 patients from 30 countries. Medicine (Baltimore) 89, 381-402. (doi:10.1097/MD.0b013e3181fdd832)
    • (2010) Medicine Baltimore , vol.89 , pp. 381-402
    • de Beaucoudrey, L.1
  • 62
    • 0035879825 scopus 로고    scopus 로고
    • Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis
    • (doi:10.1086/321999)
    • Altare F et al. 2001 Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis. J. Infect Dis. 184, 231-236. (doi:10.1086/321999)
    • (2001) J. Infect Dis. , vol.184 , pp. 231-236
    • Altare, F.1
  • 63
    • 0038195718 scopus 로고    scopus 로고
    • Clinical tuberculosis in 2 of 3 siblings with interleukin-12 receptor beta1 deficiency
    • (doi:10. 1086/375587)
    • Caragol I et al. 2003 Clinical tuberculosis in 2 of 3 siblings with interleukin-12 receptor beta1 deficiency. Clin. Infect. Dis. 37, 302-306. (doi:10. 1086/375587)
    • (2003) Clin. Infect. Dis. , vol.37 , pp. 302-306
    • Caragol, I.1
  • 65
    • 84880969980 scopus 로고    scopus 로고
    • A handheld point-of-care genomic diagnostic system
    • (doi:10.1371/journal.pone. 0070266)
    • Myers FB, Henrikson RH, Bone J, Lee LP. 2013 A handheld point-of-care genomic diagnostic system. PLoS ONE 8, e70266. (doi:10.1371/journal.pone. 0070266)
    • (2013) PLoS ONE , vol.8
    • Myers, F.B.1    Henrikson, R.H.2    Bone, J.3    Lee, L.P.4
  • 66
    • 84860538806 scopus 로고    scopus 로고
    • Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): A prospective, randomised, proof-of-concept trial
    • (doi:10.1016/S0140-6736(12)60161-5)
    • Roberts JD et al. 2012 Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial. Lancet 379, 1705-1711. (doi:10.1016/S0140-6736(12)60161-5)
    • (2012) Lancet , vol.379 , pp. 1705-1711
    • Roberts, J.D.1
  • 68
    • 0034255547 scopus 로고    scopus 로고
    • Lifetime risks, incubation period, and serial interval of tuberculosis
    • (doi:10.1093/aje/ 152.3.247)
    • Vynnycky E, Fine PE. 2000 Lifetime risks, incubation period, and serial interval of tuberculosis. Am. J. Epidemiol. 152, 247-263. (doi:10.1093/aje/ 152.3.247)
    • (2000) Am. J. Epidemiol. , vol.152 , pp. 247-263
    • Vynnycky, E.1    Fine, P.E.2
  • 69
    • 0142074318 scopus 로고    scopus 로고
    • Stability of DNA patterns and evidence of Mycobacterium tuberculosis reactivation occurring decades after the initial infection
    • (doi:10. 1086/378240)
    • Lillebaek T, Dirksen A, Vynnycky E, Baess I, Thomsen VO, Andersen AB. 2003 Stability of DNA patterns and evidence of Mycobacterium tuberculosis reactivation occurring decades after the initial infection. J. Infect Dis. 188, 1032-1039. (doi:10. 1086/378240)
    • (2003) J. Infect Dis. , vol.188 , pp. 1032-1039
    • Lillebaek, T.1    Dirksen, A.2    Vynnycky, E.3    Baess, I.4    Thomsen, V.O.5    Andersen, A.B.6
  • 70
    • 77957020774 scopus 로고    scopus 로고
    • Life-threatening infectious diseases of childhood: Single-gene inborn errors of immunity?
    • (doi:10.1111/j.1749-6632.2010.05834.x)
    • Alcais A, Quintana-Murci L, Thaler DS, Schurr E, Abel L, Casanova JL. 2010 Life-threatening infectious diseases of childhood: single-gene inborn errors of immunity? Ann. N Y Acad. Sci. 1214, 18-33. (doi:10.1111/j.1749-6632.2010.05834.x)
    • (2010) Ann. N Y Acad. Sci. , vol.1214 , pp. 18-33
    • Alcais, A.1    Quintana-Murci, L.2    Thaler, D.S.3    Schurr, E.4    Abel, L.5    Casanova, J.L.6
  • 71
    • 84884995578 scopus 로고    scopus 로고
    • Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans
    • (doi:10.1038/ng.2744)
    • Comas I et al. 2013 Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Nat. Genet. 45, 1176-1182. (doi:10.1038/ng.2744)
    • (2013) Nat. Genet. , vol.45 , pp. 1176-1182
    • Comas, I.1
  • 72
    • 84856688022 scopus 로고    scopus 로고
    • Host-pathogen coevolution in human tuberculosis
    • (doi:10.1098/rstb.2011.0316)
    • Gagneux S. 2012 Host-pathogen coevolution in human tuberculosis. Phil. Trans. R. Soc. B 367, 850-859. (doi:10.1098/rstb.2011.0316)
    • (2012) Phil. Trans. R. Soc. B , vol.367 , pp. 850-859
    • Gagneux, S.1
  • 73
    • 84867619205 scopus 로고    scopus 로고
    • Innate immune gene polymorphisms in tuberculosis
    • (doi:10.1128/IAI.00443-12)
    • Azad AK, Sadee W, Schlesinger LS. 2012 Innate immune gene polymorphisms in tuberculosis. Infect. Immun. 80, 3343-3359. (doi:10.1128/IAI.00443-12)
    • (2012) Infect. Immun. , vol.80 , pp. 3343-3359
    • Azad, A.K.1    Sadee, W.2    Schlesinger, L.S.3
  • 74
    • 74549167799 scopus 로고    scopus 로고
    • Past, present and future directions in human genetic susceptibility to tuberculosis
    • (doi:10.1111/j.1574-695X.2009.00600.x)
    • Moller M, de Wit E, Hoal EG. 2010 Past, present and future directions in human genetic susceptibility to tuberculosis. FEMS Immunol. Med. Microbiol. 58, 3-26. (doi:10.1111/j.1574-695X.2009.00600.x)
    • (2010) FEMS Immunol. Med. Microbiol. , vol.58 , pp. 3-26
    • Moller, M.1    de Wit, E.2    Hoal, E.G.3
  • 75
    • 0032485353 scopus 로고    scopus 로고
    • Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans
    • (doi:10. 1056/NEJM199803053381002)
    • Bellamy R, Ruwende C, Corrah T, McAdam KP, Whittle HC, Hill AV. 1998 Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl. J. Med. 338, 640-644. (doi:10. 1056/NEJM199803053381002)
    • (1998) N Engl. J. Med. , vol.338 , pp. 640-644
    • Bellamy, R.1    Ruwende, C.2    Corrah, T.3    McAdam, K.P.4    Whittle, H.C.5    Hill, A.V.6
  • 76
    • 33144477335 scopus 로고    scopus 로고
    • SLC11A1 (formerly NRAMP1) gene polymorphisms and tuberculosis susceptibility: A meta-analysis
    • Li HT, Zhang TT, Zhou YQ, Huang QH, Huang J. 2006 SLC11A1 (formerly NRAMP1) gene polymorphisms and tuberculosis susceptibility: a meta-analysis. Int. J. Tuberc. Lung Dis. 10, 3-12.
    • (2006) Int. J. Tuberc. Lung Dis. , vol.10 , pp. 3-12
    • Li, H.T.1    Zhang, T.T.2    Zhou, Y.Q.3    Huang, Q.H.4    Huang, J.5
  • 78
    • 24744458161 scopus 로고    scopus 로고
    • Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease
    • (doi:10. 1073/pnas.0503368102)
    • Malik S et al. 2005 Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease. Proc. Natl Acad. Sci. USA 102, 12 183-12 188. (doi:10. 1073/pnas.0503368102)
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 12183-12188
    • Malik, S.1
  • 79
    • 34047143696 scopus 로고    scopus 로고
    • Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy
    • (doi:10.1038/ng2000)
    • Alcais A et al. 2007 Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy. Nat. Genet. 39, 517-522. (doi:10.1038/ng2000)
    • (2007) Nat. Genet. , vol.39 , pp. 517-522
    • Alcais, A.1
  • 80
    • 79954600411 scopus 로고    scopus 로고
    • Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India
    • (doi:10. 1093/infdis/jir024)
    • Alter A et al. 2011 Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India. J. Infect Dis. 203, 1274-1281. (doi:10. 1093/infdis/jir024)
    • (2011) J. Infect Dis. , vol.203 , pp. 1274-1281
    • Alter, A.1
  • 81
    • 33745862748 scopus 로고    scopus 로고
    • An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults
    • (doi:10.1084/jem.20060269)
    • Baghdadi JE et al. 2006 An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults. J. Exp. Med. 203, 1679-1684. (doi:10.1084/jem.20060269)
    • (2006) J. Exp. Med. , vol.203 , pp. 1679-1684
    • Baghdadi, J.E.1
  • 82
    • 84876413165 scopus 로고    scopus 로고
    • Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region
    • (doi:10.1016/j.ajhg. 2013.01.013)
    • Grant AV et al. 2013 Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region. Am. J. Hum. Genet. 92, 407-414. (doi:10.1016/j.ajhg. 2013.01.013)
    • (2013) Am. J. Hum. Genet. , vol.92 , pp. 407-414
    • Grant, A.V.1
  • 83
    • 84859157059 scopus 로고    scopus 로고
    • The many roles of TOX in the immune system
    • (doi:10.1016/j.coi.2011.12. 001)
    • Aliahmad P, Seksenyan A, Kaye J. 2012 The many roles of TOX in the immune system. Curr. Opin. Immunol. 24, 173-177. (doi:10.1016/j.coi.2011.12. 001)
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 173-177
    • Aliahmad, P.1    Seksenyan, A.2    Kaye, J.3
  • 84
    • 82755189243 scopus 로고    scopus 로고
    • TOX is required for development of the CD4 T cell lineage gene program
    • (doi:10.4049/jimmunol.1101474)
    • Aliahmad P, Kadavallore A, de la Torre B, Kappes D, Kaye J. 2011 TOX is required for development of the CD4 T cell lineage gene program. J. Immunol. 187, 5931-5940. (doi:10.4049/jimmunol.1101474)
    • (2011) J. Immunol. , vol.187 , pp. 5931-5940
    • Aliahmad, P.1    Kadavallore, A.2    de la Torre, B.3    Kappes, D.4    Kaye, J.5
  • 85
    • 38749094821 scopus 로고    scopus 로고
    • Development of all CD4 T lineages requires nuclear factor TOX
    • (doi:10.1084/jem.20071944)
    • Aliahmad P, Kaye J. 2008 Development of all CD4 T lineages requires nuclear factor TOX. J. Exp. Med. 205, 245-256. (doi:10.1084/jem.20071944)
    • (2008) J. Exp. Med. , vol.205 , pp. 245-256
    • Aliahmad, P.1    Kaye, J.2
  • 86
    • 77956635151 scopus 로고    scopus 로고
    • Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2
    • (doi:10.1038/ng.639)
    • Thye T et al. 2010 Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nat. Genet. 42, 739-741. (doi:10.1038/ng.639)
    • (2010) Nat. Genet. , vol.42 , pp. 739-741
    • Thye, T.1
  • 87
    • 84857647593 scopus 로고    scopus 로고
    • Common variants at 11p13 are associated with susceptibility to tuberculosis
    • (doi:10.1038/ng.1080)
    • Thye T et al. 2012 Common variants at 11p13 are associated with susceptibility to tuberculosis. Nat. Genet. 44, 257-259. (doi:10.1038/ng.1080)
    • (2012) Nat. Genet. , vol.44 , pp. 257-259
    • Thye, T.1
  • 88
    • 84892473992 scopus 로고    scopus 로고
    • Genome-wide association study of ancestry-specific TB risk in the South African coloured population
    • (doi:10.1093/hmg/ ddt462)
    • Chimusa ER, Zaitlen N, Daya M, Moller M, van Helden PD, Mulder NJ, Price AL, Hoal EG. 2013 Genome-wide association study of ancestry-specific TB risk in the South African coloured population. Hum. Mol. Genet. 23, 796-809. (doi:10.1093/hmg/ ddt462)
    • (2013) Hum. Mol. Genet , vol.23 , pp. 796-809
    • Chimusa, E.R.1    Zaitlen, N.2    Daya, M.3    Moller, M.4    van Helden, P.D.5    Mulder, N.J.6    Price, A.L.7    Hoal, E.G.8
  • 89
    • 84862880135 scopus 로고    scopus 로고
    • Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis
    • (doi:10.1038/jhg.2012.35)
    • Mahasirimongkol S et al. 2012 Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis. J. Hum. Genet. 57, 363-367. (doi:10.1038/jhg.2012.35)
    • (2012) J. Hum. Genet. , vol.57 , pp. 363-367
    • Mahasirimongkol, S.1
  • 90
    • 77649119986 scopus 로고    scopus 로고
    • TB: Screening for responses to a vile visitor
    • (doi:10.1016/j.cell.2010.02.030)
    • Behr M, Schurr E, Gros P. 2010 TB: screening for responses to a vile visitor. Cell 140, 615-618. (doi:10.1016/j.cell.2010.02.030)
    • (2010) Cell , vol.140 , pp. 615-618
    • Behr, M.1    Schurr, E.2    Gros, P.3
  • 91
    • 77649128120 scopus 로고    scopus 로고
    • The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans
    • (doi:10.1016/j. cell.2010.02.013)
    • Tobin DM et al. 2010 The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 140, 717-730. (doi:10.1016/j. cell.2010.02.013)
    • (2010) Cell , vol.140 , pp. 717-730
    • Tobin, D.M.1
  • 92
    • 0033859730 scopus 로고    scopus 로고
    • Genetic predisposition to clinical tuberculosis: Bridging the gap between simple and complex inheritance
    • (doi:10.1086/303033)
    • Abel L, Casanova JL. 2000 Genetic predisposition to clinical tuberculosis: bridging the gap between simple and complex inheritance. Am. J. Hum. Genet. 67, 274-277. (doi:10.1086/303033)
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 274-277
    • Abel, L.1    Casanova, J.L.2
  • 93
    • 77956331627 scopus 로고    scopus 로고
    • Integrating common and rare genetic variation in diverse human populations
    • (doi:10.1038/nature09298)
    • Altshuler DM et al. 2010 Integrating common and rare genetic variation in diverse human populations. Nature 467, 52-58. (doi:10.1038/nature09298)
    • (2010) Nature , vol.467 , pp. 52-58
    • Altshuler, D.M.1
  • 94
    • 77952574849 scopus 로고    scopus 로고
    • Uncovering the roles of rare variants in common disease through wholegenome sequencing
    • (doi:10.1038/nrg2779)
    • Cirulli ET, Goldstein DB. 2010 Uncovering the roles of rare variants in common disease through wholegenome sequencing. Nat. Rev. Genet. 11, 415-425. (doi:10.1038/nrg2779)
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 415-425
    • Cirulli, E.T.1    Goldstein, D.B.2
  • 95
    • 9244245196 scopus 로고    scopus 로고
    • Bacillus Calmette Guerin triggers the IL-12/IFN-gamma axis by an IRAK-4-and NEMO-dependent, non-cognate interaction between monocytes, NK, and T lymphocytes
    • (doi:10.1002/eji. 200425221)
    • Feinberg J et al. 2004 Bacillus Calmette Guerin triggers the IL-12/IFN-gamma axis by an IRAK-4-and NEMO-dependent, non-cognate interaction between monocytes, NK, and T lymphocytes. Eur. J. Immunol. 34, 3276-3284. (doi:10.1002/eji. 200425221)
    • (2004) Eur. J. Immunol. , vol.34 , pp. 3276-3284
    • Feinberg, J.1
  • 97
    • 41149169282 scopus 로고    scopus 로고
    • ALOX5 variants associated with susceptibility to human pulmonary tuberculosis
    • (doi:10.1093/ hmg/ddm378)
    • Herb F et al. 2008 ALOX5 variants associated with susceptibility to human pulmonary tuberculosis. Hum. Mol. Genet. 17, 1052-1060. (doi:10.1093/ hmg/ddm378)
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 1052-1060
    • Herb, F.1
  • 98
    • 70349672696 scopus 로고    scopus 로고
    • Autophagy gene variant IRGM-261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains
    • (doi:10.1371/journal.ppat.1000577)
    • Intemann CD et al. 2009 Autophagy gene variant IRGM-261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains. PLoS Pathog. 5, e1000577. (doi:10.1371/journal.ppat.1000577)
    • (2009) PLoS Pathog. , vol.5
    • Intemann, C.D.1
  • 99
    • 50949090423 scopus 로고    scopus 로고
    • The clinical consequences of strain diversity in Mycobacterium tuberculosis
    • (doi:10.1016/j.trstmh.2008.03.025)
    • Nicol MP, Wilkinson RJ. 2008 The clinical consequences of strain diversity in Mycobacterium tuberculosis. Trans. R. Soc. Trop. Med. Hyg. 102, 955-965. (doi:10.1016/j.trstmh.2008.03.025)
    • (2008) Trans. R. Soc. Trop. Med. Hyg. , vol.102 , pp. 955-965
    • Nicol, M.P.1    Wilkinson, R.J.2
  • 100
    • 84860316430 scopus 로고    scopus 로고
    • Cell type-specific eQTLs in the human immune system
    • (doi:10.1038/ng.2258)
    • Gregersen PK. 2012 Cell type-specific eQTLs in the human immune system. Nat. Genet. 44, 478-480. (doi:10.1038/ng.2258)
    • (2012) Nat. Genet. , vol.44 , pp. 478-480
    • Gregersen, P.K.1
  • 101
    • 77950460661 scopus 로고    scopus 로고
    • Understanding mechanisms underlying human gene expression variation with RNA sequencing
    • (doi:10. 1038/nature08872)
    • Pickrell JK et al. 2010 Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature 464, 768-772. (doi:10. 1038/nature08872)
    • (2010) Nature , vol.464 , pp. 768-772
    • Pickrell, J.K.1
  • 102
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • (doi:10. 1038/nature09247)
    • Berry MP et al. 2010 An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466, 973-977. (doi:10. 1038/nature09247)
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1
  • 103
    • 84872978097 scopus 로고    scopus 로고
    • Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response
    • (doi:10.1093/infdis/jis499)
    • Cliff JM et al. 2013 Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response. J. Infect Dis. 207, 18-29. (doi:10.1093/infdis/jis499)
    • (2013) J. Infect Dis. , vol.207 , pp. 18-29
    • Cliff, J.M.1
  • 105
    • 84866686896 scopus 로고    scopus 로고
    • Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis
    • (doi:10.1371/journal.pone.0045839)
    • Ottenhoff TH et al. 2012 Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis. PLoS ONE 7, e45839. (doi:10.1371/journal.pone.0045839)
    • (2012) PLoS ONE , vol.7
    • Ottenhoff, T.H.1
  • 106
    • 84881104975 scopus 로고    scopus 로고
    • Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers
    • (doi:10.1371/ journal.pone.0070630)
    • Bloom CI et al. 2013 Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers. PLoS ONE 8, e70630. (doi:10.1371/ journal.pone.0070630)
    • (2013) PLoS ONE , vol.8
    • Bloom, C.I.1
  • 107
    • 84898018651 scopus 로고    scopus 로고
    • Systems approaches to studying the immune response in tuberculosis
    • (doi:10.1016/j.coi.2013.08.003)
    • Berry MP, Blankley S, Graham CM, Bloom CI, O'Garra A. 2013 Systems approaches to studying the immune response in tuberculosis. Curr. Opin. Immunol. 25, 579-587. (doi:10.1016/j.coi.2013.08.003)
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 579-587
    • Berry, M.P.1    Blankley, S.2    Graham, C.M.3    Bloom, C.I.4    O'Garra, A.5
  • 108
    • 84856387609 scopus 로고    scopus 로고
    • Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection
    • (doi:10.1073/pnas. 1115761109)
    • Barreiro LB, Tailleux L, Pai AA, Gicquel B, Marioni JC, Gilad Y. 2012 Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc. Natl Acad. Sci. USA 109, 1204-1209. (doi:10.1073/pnas. 1115761109)
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 1204-1209
    • Barreiro, L.B.1    Tailleux, L.2    Pai, A.A.3    Gicquel, B.4    Marioni, J.C.5    Gilad, Y.6
  • 109
    • 84866406017 scopus 로고    scopus 로고
    • DNA methylation: A promising landscape for immune system-related diseases
    • (doi:10.1016/j.tig.2012. 06.005)
    • Suarez-Alvarez B, Rodriguez RM, Fraga MF, Lopez-Larrea C. 2012 DNA methylation: a promising landscape for immune system-related diseases. Trends Genet. 28, 506-514. (doi:10.1016/j.tig.2012. 06.005)
    • (2012) Trends Genet. , vol.28 , pp. 506-514
    • Suarez-Alvarez, B.1    Rodriguez, R.M.2    Fraga, M.F.3    Lopez-Larrea, C.4
  • 110
    • 84856498057 scopus 로고    scopus 로고
    • DNA methylome analysis using short bisulfite sequencing data
    • (doi:10.1038/nmeth.1828)
    • Krueger F, Kreck B, Franke A, Andrews SR. 2012 DNA methylome analysis using short bisulfite sequencing data. Nat. Methods 9, 145-151. (doi:10.1038/nmeth.1828)
    • (2012) Nat. Methods , vol.9 , pp. 145-151
    • Krueger, F.1    Kreck, B.2    Franke, A.3    Andrews, S.R.4
  • 111
    • 77249137168 scopus 로고    scopus 로고
    • Principles and challenges of genomewide DNA methylation analysis
    • (doi:10.1038/nrg2732)
    • Laird PW. 2010 Principles and challenges of genomewide DNA methylation analysis. Nat. Rev. Genet. 11, 191-203. (doi:10.1038/nrg2732)
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 191-203
    • Laird, P.W.1
  • 112
    • 84860581386 scopus 로고    scopus 로고
    • Can the battle against tuberculosis gain from epigenetic research?
    • (doi:10.1016/j.tim.2012.03.002)
    • Esterhuyse MM, Linhart HG, Kaufmann SH. 2012 Can the battle against tuberculosis gain from epigenetic research? Trends Microbiol. 20, 220-226. (doi:10.1016/j.tim.2012.03.002)
    • (2012) Trends Microbiol. , vol.20 , pp. 220-226
    • Esterhuyse, M.M.1    Linhart, H.G.2    Kaufmann, S.H.3
  • 113
    • 84876685184 scopus 로고    scopus 로고
    • Epigenetic methylations and their connections with metabolism
    • (doi:10.1007/s00018-013-1293-5)
    • Chiacchiera F, Piunti A, Pasini D. 2013 Epigenetic methylations and their connections with metabolism. Cell Mol. Life Sci. 70, 1495-1508. (doi:10.1007/s00018-013-1293-5)
    • (2013) Cell Mol. Life Sci. , vol.70 , pp. 1495-1508
    • Chiacchiera, F.1    Piunti, A.2    Pasini, D.3
  • 114
    • 84875755814 scopus 로고    scopus 로고
    • Influence of metabolism on epigenetics and disease
    • (doi:10.1016/j.cell.2013.03.004)
    • Kaelin Jr WG, McKnight SL. 2013 Influence of metabolism on epigenetics and disease. Cell 153, 56-69. (doi:10.1016/j.cell.2013.03.004)
    • (2013) Cell , vol.153 , pp. 56-69
    • Kaelin Jr., W.G.1    McKnight, S.L.2
  • 115
    • 77953808473 scopus 로고    scopus 로고
    • Next-generation genomics: An integrative approach
    • (doi:10.1038/nrg2795)
    • Hawkins RD, Hon GC, Ren B. 2010 Next-generation genomics: an integrative approach. Nat. Rev. Genet. 11, 476-486. (doi:10.1038/nrg2795)
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 476-486
    • Hawkins, R.D.1    Hon, G.C.2    Ren, B.3
  • 116
    • 84872839742 scopus 로고    scopus 로고
    • Genomic modulators of the immune response
    • (doi:10.1016/j.tig.2012.10.006)
    • Knight JC. 2013 Genomic modulators of the immune response. Trends Genet. 29, 74-83. (doi:10.1016/j.tig.2012.10.006)
    • (2013) Trends Genet. , vol.29 , pp. 74-83
    • Knight, J.C.1
  • 117
    • 77952316129 scopus 로고    scopus 로고
    • Experimental models used to study human tuberculosis
    • (doi:10.1016/S0065-2164(10)71003-0)
    • O'Toole R. 2010 Experimental models used to study human tuberculosis. Adv. Appl. Microbiol. 71, 75-89. (doi:10.1016/S0065-2164(10)71003-0)
    • (2010) Adv. Appl. Microbiol. , vol.71 , pp. 75-89
    • O'Toole, R.1
  • 118
    • 33646143975 scopus 로고    scopus 로고
    • Lessons from experimental Mycobacterium tuberculosis infections
    • (doi:10.1016/j.micinf.2005.10.033)
    • Flynn JL. 2006 Lessons from experimental Mycobacterium tuberculosis infections. Microbes Infect. 8, 1179-1188. (doi:10.1016/j.micinf.2005.10.033)
    • (2006) Microbes Infect. , vol.8 , pp. 1179-1188
    • Flynn, J.L.1
  • 119
    • 70249142207 scopus 로고    scopus 로고
    • Trends in tuberculosis incidence and their determinants in 134 countries
    • (doi:10.2471/BLT.08. 058453)
    • Dye C, Lonnroth K, Jaramillo E, Williams BG, Raviglione M. 2009 Trends in tuberculosis incidence and their determinants in 134 countries. Bull World Health Organ. 87, 683-691. (doi:10.2471/BLT.08. 058453)
    • (2009) Bull World Health Organ. , vol.87 , pp. 683-691
    • Dye, C.1    Lonnroth, K.2    Jaramillo, E.3    Williams, B.G.4    Raviglione, M.5
  • 121
    • 79953899871 scopus 로고    scopus 로고
    • Developing a tuberculosis transmission model that accounts for changes in population health
    • (doi:10.1177/0272989X10369001)
    • Oxlade O, Schwartzman K, Benedetti A, Pai M, Heymann J, Menzies D. 2011 Developing a tuberculosis transmission model that accounts for changes in population health. Med. Decis. Making 31, 53-68. (doi:10.1177/0272989X10369001)
    • (2011) Med. Decis. Making , vol.31 , pp. 53-68
    • Oxlade, O.1    Schwartzman, K.2    Benedetti, A.3    Pai, M.4    Heymann, J.5    Menzies, D.6
  • 123
    • 79959486818 scopus 로고    scopus 로고
    • Immunogenicity of the tuberculosis vaccine MVA85A is reduced by coadministration with EPI vaccines in a randomized controlled trial in Gambian infants
    • (doi:10.1126/scitranslmed.3002461)
    • Ota MO et al. 2011 Immunogenicity of the tuberculosis vaccine MVA85A is reduced by coadministration with EPI vaccines in a randomized controlled trial in Gambian infants. Sci. Transl. Med. 3, 88ra56. (doi:10.1126/scitranslmed.3002461)
    • (2011) Sci. Transl. Med. , vol.3
    • Ota, M.O.1
  • 124
    • 84875382846 scopus 로고    scopus 로고
    • Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: A randomised, placebo-controlled phase 2b trial
    • (doi:10.1016/S0140-6736(13)60177-4)
    • Tameris MD et al. 2013 Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial. Lancet 381, 1021-1028. (doi:10.1016/S0140-6736(13)60177-4)
    • (2013) Lancet , vol.381 , pp. 1021-1028
    • Tameris, M.D.1
  • 125
    • 0032942535 scopus 로고    scopus 로고
    • Genetically susceptible mice remain proportionally more susceptible to tuberculosis after vaccination
    • (doi:10.1046/j.1365-2567.1999.00663.x)
    • Medina E, North RJ. 1999 Genetically susceptible mice remain proportionally more susceptible to tuberculosis after vaccination. Immunology 96, 16-21. (doi:10.1046/j.1365-2567.1999.00663.x)
    • (1999) Immunology , vol.96 , pp. 16-21
    • Medina, E.1    North, R.J.2
  • 126
    • 20444401506 scopus 로고    scopus 로고
    • Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis
    • (doi:10.1164/rccm.200409-1200OC)
    • Verver S et al. 2005 Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis. Am. J. Respir. Crit. Care Med. 171, 1430-1435. (doi:10.1164/rccm.200409-1200OC)
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , pp. 1430-1435
    • Verver, S.1


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