Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis

Journal of Human Genetics

Volumn 57, Issue 6, 2012, Pages 363-367

  Mahasirimongkol, Surakameth ^a,b   Yanai, Hideki ^b,c   Mushiroda, Taisei ^d   Promphittayarat, Watoo ^a,d   Wattanapokayakit, Sukanya ^a   Phromjai, Jurairat ^d   Yuliwulandari, Rika ^b   Wichukchinda, Nuanjun ^a   Yowang, Amara ^a,d   Yamada, Norio ^e   Kantipong, Patcharee ^a   Takahashi, Atsushi ^d   Kubo, Michiaki ^d   Sawanpanyalert, Pathom ^a   Kamatani, Naoyuki ^d   Nakamura, Yusuke ^f   Tokunaga, Katsushi ^b  

^a MINISTRY OF PUBLIC HEALTH   (Thailand)

^b UNIVERSITY OF TOKYO   (Japan)

^c Japan Anti Tuberculosis Association   (Japan)

^d RIKEN   (Japan)

^e RESEARCH INSTITUTE OF TUBERCULOSIS   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Asians; genome wide association analyses; GWAS; Japan; Thailand; tuberculosis

Indexed keywords

ADULT; AGED; ASIAN; CONTROLLED STUDY; EFFECT SIZE; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; THAILAND; TUBERCULOSIS;

AGE FACTORS; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; JAPAN; META-ANALYSIS AS TOPIC; POLYMORPHISM, SINGLE NUCLEOTIDE; QUALITY CONTROL; THAILAND; TUBERCULOSIS;

THAIS;

EID: 84862880135     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2012.35     Document Type: Review

References (27)

1. Mira, M. T., Alcais, A., Van Thuc, N., Thai, V. H., Huong, N. T., Ba, N. N. et al. Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population. Nat. Genet. 33, 412-415 (2003). (Pubitemid 36278860)
2. Mira, M. T., Alcais, A., Nguyen, V. T., Moraes, M. O., Di Flumeri, C., Vu, H. T. et al. Susceptibility to leprosy is associated with PARK2 and PACRG. Nature 427, 636-640 (2004). (Pubitemid 38248483)
3. Alcais, A., Alter, A., Antoni, G., Orlova, M., Nguyen, V. T., Singh, M. et al. Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy. Nat. Genet. 39, 517-522 (2007). (Pubitemid 46514779)
4. Zhang, F. R., Huang, W., Chen, S. M., Sun, L. D., Liu, H., Li, Y. et al. Genome-wide association study of leprosy. N Engl J Med 361, 2609-2618 (2009).
5. Jallow, M., Teo, Y. Y., Small, K. S., Rockett, K. A., Deloukas, P., Clark, T. G. et al. Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat. Genet. 41, 657-665 (2009).
6. Davila, S., Wright, V. J., Khor, C. C., Sim, K. S., Binder, A., Breunis, W. B. et al. Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. Nat. Genet. 42, 772-776 (2010).
7. Thye, T., Vannberg, F. O., Wong, S. H., Owusu-Dabo, E., Osei, I., Gyapong, J. et al. Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nat. Genet. 42, 739-741 (2010).
8. Sutherland, I., Svandova, E. Radhakrishna, S. The development of clinical tuberculosis following infection with tubercle bacilli. 1. A theoretical model for the development of clinical tuberculosis following infection, linking from data on the risk of tuberculous infection and the incidence of clinical tuberculosis in the Netherlands. Tu b e r c l e 63, 255-268 (1982).
9. Alcais, A., Fieschi, C., Abel, L. Casanova, J. L. Tuberculosis in children and adults: two distinct genetic diseases. J Exp Med 202, 1617-1621 (2005). (Pubitemid 41815866)
10. Mahasirimongkol, S., Yanai, H., Nishida, N., Ridruechai, C., Matsushita, I., Ohashi, J. et al. Genome-wide SNP-based linkage analysis of tuberculosis in Thais. Genes Immun 10, 77-83 (2009).
11. Bellamy, R., Beyers, N., McAdam, K. P., Ruwende, C., Gie, R., Samaai, P. et al. Genetic susceptibility to tuberculosis in Africans: a genome-wide scan. Proc. Natl Acad. Sci. USA 97, 8005-8009 (2000). (Pubitemid 30460763)
12. Cooke, G. S., Campbell, S. J., Bennett, S., Lienhardt, C., McAdam, K. P., Sirugo, G. et al. Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis. Am. J. Respir. Crit. Care Med. 178, 203-207 (2008). (Pubitemid 351957779)
13. Mahasirimongkol, S., Chantratita, W., Promso, S., Pasomsab, E., Jinawath, N., Jongjaroenprasert, W. et al. Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais. J. Hum. Genet. 51, 896-904 (2006). (Pubitemid 44465700)
14. Hirakawa, M., Tanaka, T., Hashimoto, Y., Kuroda, M., Takagi, T., Nakamura, Y. JSNP: a database of common gene variations in the Japanese population. Nucl. Acids Res. 30, 158-162 (2002). (Pubitemid 34679529)
15. Ohnishi, Y., Tanaka, T., Ozaki, K., Yamada, R., Suzuki, H. Nakamura, Y. A high-throughput SNP typing system for genome-wide association studies. J. Hum. Genet. 46, 471-477 (2001). (Pubitemid 32744120)
16. Nuinoon, M., Makarasara, W., Mushiroda, T., Setianingsih, I., Wahidiyat, P. A., Sripichai, O. et al. A genome-wide association identified the common genetic variants influence disease severity in beta(0)-thalassemia/hemoglobin E. Hum. Genet. 127, 303-314 (2010).
17. Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J. et al. Finding the missing heritability of complex diseases. Nature 461, 747-753 (2009).
18. Rienthong, D., Ajawatanawong, P., Rienthong, S., Smithtikarn, S., Akarasewi, P., Chaiprasert, A. et al. Restriction fragment length polymorphism study of nationwide samples of Mycobacterium tuberculosis in Thailand, 1997-1998. Int. J. Tuberc. Lung Dis. 9, 576-581 (2005). (Pubitemid 40646846)
19. Research Institute of Tuberculosis J. Tuberculosis Annual Report 2008-Series 1. Summary of TB notification statistics in 2008. Kekkaku 84, 693-696 (2009).
20. Siriarayapon, P., Yanai, H., Glynn, J. R., Yanpaisarn, S. Uthaivoravit, W. The evolving epidemiology of HIV infection and tuberculosis in northern Thailand. J. Acquir. Immune Defic. Syndr. 31, 80-89 (2002).
21. Liu, C., Batliwalla, F., Li, W., Lee, A., Roubenoff, R., Beckman, E. et al. Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Mol. Med. 14, 575-581 (2008).
22. Berry, M. P., Graham, C. M., McNab, F. W., Xu, Z., Bloch, S. A., Oni, T. et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466, 973-977 (2010).
23. Ritz, N. Curtis, N. Mapping the global use of different BCG vaccine strains. Tuberculosis (Edinb) 89, 248-251 (2009).
24. Yamamoto, S. Yamamoto, T. Historical review of BCG vaccine in Japan. Jpn. J. Infect. Dis. 60, 331-336 (2007). (Pubitemid 350177135)
25. Gagneux, S., DeRiemer, K., Van, T., Kato-Maeda, M., de Jong, B. C., Narayanan, S. et al. Variable host-pathogen compatibility in Mycobacterium tuberculosis. Proc. Natl Acad. Sci. USA 103, 2869-2873 (2006).
26. Caws, M., Thwaites, G., Dunstan, S., Hawn, T. R., Lan, N. T., Thuong, N. T. et al. The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog. 4, e1000034 (2008).
27. Ledingham, J., Wilkinson, C. Deighton, C. British Thoracic Society (BTS) recommendations for assessing risk and managing tuberculosis in patients due to start anti-TNF-{alpha} treatments. Rheumatology (Oxford) 44, 1205-1206 (2005). (Pubitemid 41487949)