Role of the lower and upper intestine in the production and absorption of gut microbiota-derived PUFA metabolites

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Druart, Céline ^a   Neyrinck, Audrey M ^a   Vlaeminck, Bruno ^b   Fievez, Veerle ^b   Cani, Patrice D ^a   Delzenne, Nathalie M ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LINSEED OIL; LIPOPROTEIN LIPASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; SUNFLOWER OIL; TYLOXAPOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL METABOLISM; CECUM; COLON; CONTROLLED STUDY; FATTY ACID ANALYSIS; GAS CHROMATOGRAPHY; HORMONAL REGULATION; HYDROLYSIS; ILEUM; INTESTINE ABSORPTION; INTESTINE FLORA; JEJUNUM; LIPID STORAGE; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; SAPONIFICATION; TISSUE DISTRIBUTION;

ANALYSIS OF VARIANCE; ANIMALS; BACTERIA; FATTY ACIDS, NONESTERIFIED; FATTY ACIDS, UNSATURATED; INTESTINES; LINOLEIC ACIDS, CONJUGATED; LINSEED OIL; MALE; MICE; MICE, INBRED C57BL; MICROBIOTA; PLANT OILS; TRIGLYCERIDES;

EID: 84900304172     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087560     Document Type: Article

References (48)

1. Tremaroli V, Backhed F (2012) Functional interactions between the gut microbiota and host metabolism. Nature 489: 242-249.
2. Cani PD, Osto M, Geurts L, Everard A (2012) Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity. Gut Microbes 3: 279-288.
3. Cani PD, Delzenne NM (2011) The gut microbiome as therapeutic target. Pharmacol Ther 130: 202-212.
4. Maynard CL, Elson CO, Hatton RD, Weaver CT (2012) Reciprocal interactions of the intestinal microbiota and immune system. Nature 489: 231-241.
5. Nicholson JK, Holmes E, Kinross J, Burcelin R, Gibson G, et al. (2012) Host-gut microbiota metabolic interactions. Science 336: 1262-1267.
6. Chilliard Y, Glasser F, Ferlay A, Bernard L, Rouel J, et al. (2007) Diet, rumen biohydrogenation and nutritional quality of cow and goat milk fat. Eur J Lipid Sci Technol 109: 828-855. (Pubitemid 47313000)
7. Devillard E, McIntosh FM, Duncan SH, Wallace RJ (2007) Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid. J Bacteriol 189: 2566-2570. (Pubitemid 46411372)
8. Gorissen L, Raes K, Weckx S, Dannenberger D, Leroy F, et al. (2010) Production of conjugated linoleic acid and conjugated linolenic acid isomers by Bifidobacterium species. Appl Microbiol Biotechnol 87: 2257-2266.
9. O'Shea EF, Cotter PD, Stanton C, Ross RP, Hill C (2012) Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: bacteriocins and conjugated linoleic acid. Int J Food Microbiol 152: 189-205.
10. Coakley M, Ross RP, Nordgren M, Fitzgerald G, Devery R, et al. (2003) Conjugated linoleic acid biosynthesis by human-derived Bifidobacterium species. J Appl Microbiol 94: 138-145. (Pubitemid 36051315)
11. Or-Rashid MM, Alzahal O, McBride BW (2011) Comparative studies on the metabolism of linoleic acid by rumen bacteria, protozoa, and their mixture in vitro. Appl Microbiol Biotechnol 89: 387-395.
12. Wahle KW, Heys SD, Rotondo D (2004) Conjugated linoleic acids: are they beneficial or detrimental to health? Prog Lipid Res 43: 553-587. (Pubitemid 39441346)
13. Reynolds CM, Roche HM (2010) Conjugated linoleic acid and inflammatory cell signalling. Prostaglandins Leukot Essent Fatty Acids 82: 199-204.
14. Kelley NS, Hubbard NE, Erickson KL (2007) Conjugated linoleic acid isomers and cancer. J Nutr 137: 2599-2607. (Pubitemid 350255285)
15. Coakley M, Banni S, Johnson MC, Mills S, Devery R, et al. (2009) Inhibitory effect of conjugated alpha-linolenic acid from bifidobacteria of intestinal origin on SW480 cancer cells. Lipids 44: 249-256.
16. Miranda J, Lasa A, Fernandez-Quintela A, Garcia-Marzo C, Ayo J, et al. (2011) cis-9,trans-11,cis-15 and cis-9,trans-13,cis-15 CLNA mixture activates PPAR-alpha in HEK293 and reduces triacylglycerols in 3T3-L1 cells. Lipids 46: 1005-1012.
17. Evans M, Brown J, McIntosh M (2002) Isomer-specific effects of conjugated linoleic acid (CLA) on adiposity and lipid metabolism. J Nutr Biochem 13: 508.
18. Churruca I, Fernandez-Quintela A, Portillo MP (2009) Conjugated linoleic acid isomers: differences in metabolism and biological effects. Biofactors 35: 105-111.
19. Tricon S, Burdge GC, Williams CM, Calder PC, Yaqoob P (2005) The effects of conjugated linoleic acid on human health-related outcomes. Proc Nutr Soc 64: 171-182. (Pubitemid 40813539)
20. Tricon S, Yaqoob P (2006) Conjugated linoleic acid and human health: a critical evaluation of the evidence. Curr Opin Clin Nutr Metab Care 9: 105-110. (Pubitemid 44090032)
21. Field CJ, Blewett HH, Proctor S, Vine D (2009) Human health benefits of vaccenic acid. Appl Physiol Nutr Metab 34: 979-991.
22. Park Y, Storkson JM, Albright KJ, Liu W, Pariza MW (2005) Biological activities of conjugated fatty acids: conjugated eicosadienoic (conj. 20:2delta(c11,t13/t12,c14)), eicosatrienoic (conj. 20:3delta(c8,t12,c14)), and heneicosadienoic (conj. 21:2delta(c12,t14/c13,t15)) acids and other metabolites of conjugated linoleic acid. Biochim Biophys Acta 1687: 120-129. (Pubitemid 40228992)
23. Druart C, Neyrinck AM, Dewulf EM, De Backer FC, Possemiers S, et al. (2013) Implication of fermentable carbohydrates targeting the gut microbiota on conjugated linoleic acid production in high-fat-fed mice. Br J Nutr: 1-14.
24. Sartor RB (2008) Microbial influences in inflammatory bowel diseases. Gastroenterology 134: 577-594.
25. O'Hara AM, Shanahan F (2006) The gut flora as a forgotten organ. EMBO Rep 7: 688-693. (Pubitemid 43986264)
26. Cotter PD (2011) Small intestine and microbiota. Curr Opin Gastroenterol 27: 99-105.
27. Niot I, Poirier H, Tran TT, Besnard P (2009) Intestinal absorption of long-chain fatty acids: evidence and uncertainties. Prog Lipid Res 48: 101-115.
28. Borensztajn J, Rone MS, Kotlar TJ (1976) The inhibition in vivo of lipoprotein lipase (clearing-factor lipase) activity by triton WR-1339. Biochem J 156: 539-543.
29. Kramer JK, Hernandez M, Cruz-Hernandez C, Kraft J, Dugan ME (2008) Combining results of two GC separations partly achieves determination of all cis and trans 16:1, 18:1, 18:2 and 18:3 except CLA isomers of milk fat as demonstrated using Ag-ion SPE fractionation. Lipids 43: 259-273.
30. Stefanov I, Baeten V, Abbas O, Colman E, Vlaeminck B, et al. (2010) Analysis of Milk Odd- and Branched-Chain Fatty Acids Using Fourier Transform (FT)-Raman Spectroscopy. J Agric Food Chem.
31. Precht D, Molkentin J, McGuire MA, McGuire MK, Jensen RG (2001) Overestimates of oleic and linoleic acid contents in materials containing trans fatty acids and analyzed with short packed gas chromatographic columns. Lipids 36: 213-216. (Pubitemid 32216928)
32. Destaillats F, Golay PA, Joffre F, de Wispelaere M, Hug B, et al. (2007) Comparison of available analytical methods to measure trans-octadecenoic acid isomeric profile and content by gas-liquid chromatography in milk fat. J Chromatogr A 1145: 222-228. (Pubitemid 46335800)
33. Dubois V, Breton S, Linder M, Fanni J, Parmentier M (2007) Fatty acid profiles of 80 vegetable oils with regard to their nutritional potential. Eur J Lipid Sci Technol 109: 710-732. (Pubitemid 47191330)
34. Neyrinck AM, Possemiers S, Druart C, Van de Wiele T, De Backer F, et al. (2011) Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides/Prevotella in diet-induced obese mice. PLoS One 6: e20944.
35. de Wit N, Derrien M, Bosch-Vermeulen H, Oosterink E, Keshtkar S, et al. (2012) Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine. Am J Physiol Gastrointest Liver Physiol 303: G589-599.
36. Huang EY, Leone VA, Devkota S, Wang Y, Brady MJ, et al. (2013) Composition of dietary fat source shapes gut microbiota architecture and alters host inflammatory mediators in mouse adipose tissue. JPEN J Parenter Enteral Nutr 37: 746-754.
37. Mujico JR, Baccan GC, Gheorghe A, Diaz LE, Marcos A (2013) Changes in gut microbiota due to supplemented fatty acids in diet-induced obese mice. Br J Nutr: 1-10.
38. Zoetendal EG, Raes J, van den Bogert B, Arumugam M, Booijink CC, et al. (2012) The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates. ISME J 6: 1415-1426.
39. Hayashi H, Takahashi R, Nishi T, Sakamoto M, Benno Y (2005) Molecular analysis of jejunal, ileal, caecal and recto-sigmoidal human colonic microbiota using 16S rRNA gene libraries and terminal restriction fragment length polymorphism. J Med Microbiol 54: 1093-1101. (Pubitemid 41566781)
40. Lerch S, Shingfield KJ, Ferlay A, Vanhatalo A, Chilliard Y (2012) Rapeseed or linseed in grass-based diets: effects on conjugated linoleic and conjugated linolenic acid isomers in milk fat from Holstein cows over 2 consecutive lactations. J Dairy Sci 95: 7269-7287.
41. Wang M, Ahrne S, Jeppsson B, Molin G (2005) Comparison of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S rRNA genes. FEMS Microbiol Ecol 54: 219-231. (Pubitemid 41317922)
42. Szentkuti L, Lorenz K (1995) The thickness of the mucus layer in different segments of the rat intestine. Histochem J 27: 466-472.
43. Vinolo MA, Hirabara SM, Curi R (2012) G-protein-coupled receptors as fat sensors. Curr Opin Clin Nutr Metab Care 15: 112-116.
44. Schmidt J, Liebscher K, Merten N, Grundmann M, Mielenz M, et al. (2011) Conjugated linoleic acids mediate insulin release through islet G protein-coupled receptor FFA1/GPR40. J Biol Chem 286: 11890-11894.
45. Edfalk S, Steneberg P, Edlund H (2008) Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes 57: 2280-2287.
46. Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, et al. (2005) Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11: 90-94. (Pubitemid 40215843)
47. Bassaganya-Riera J, Viladomiu M, Pedragosa M, De Simone C, Carbo A, et al. (2012) Probiotic bacteria produce conjugated linoleic acid locally in the gut that targets macrophage PPAR gamma to suppress colitis. PLoS One 7: e31238.
48. Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, et al. (2008) Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57: 1470-1481.