Formulation and evaluation of novel reverse microemulsions containing salmon calcitonin in hydrofluoroalkane propellants

International Journal of Pharmaceutics

Volumn 466, Issue 1-2, 2014, Pages 390-399

  Shan, Ziyun ^a   Tan, Yinhe ^a   Qin, Lingzhen ^a   Li, Ge ^b   Pan, Xin ^a   Wang, Zhouhua ^a   Yu, Xiu ^a   Wang, Qinruo ^c   Wu, Chuanbin ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Guangzhou Crystal Technology Co Ltd   (China)

^c GUANGDONG UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Aerosolization; Fine particle fraction; Hypocalcemia activity; Pressurized metered dose inhaler; Reverse microemulsion; Salmon calcitonin

Indexed keywords

ALCOHOL; CALCIUM; NORFLURANE; POLOXAMER; PROPELLANT; SALCATONIN; SURFACTANT; AEROSOL; CALCITONIN; EMULSION; FLUORINATED HYDROCARBON;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM BLOOD LEVEL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HUMAN; HUMAN CELL; HYPOCALCEMIA; MALE; METERED DOSE INHALER; MICROEMULSION; MTT ASSAY; NONHUMAN; PARTICLE SIZE; PRESSURIZED METERED DOSE INHALER; PRIORITY JOURNAL; RAT; WATER CONTENT; ANIMAL; BLOOD; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; EMULSION; MEDICINAL CHEMISTRY; TUMOR CELL LINE; WISTAR RAT;

AEROSOL PROPELLANTS; AEROSOLS; ANIMALS; CALCITONIN; CALCIUM; CELL LINE, TUMOR; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; EMULSIONS; ETHANOL; HUMANS; HYDROCARBONS, FLUORINATED; MALE; POLOXAMER; RATS, WISTAR; SURFACE-ACTIVE AGENTS;

EID: 84899988524     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.03.032     Document Type: Article

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