A novel bottom-up process to produce nanoparticles containing protein and peptide for suspension in hydrofluoroalkane propellants

International Journal of Pharmaceutics

Volumn 413, Issue 1-2, 2011, Pages 167-173

  Tan, Yinhe ^a   Yang, Zhiwen ^a,b   Peng, Xinsheng ^a,c   Xin, Feng ^a   Xu, Yuehong ^a   Feng, Min ^a   Zhao, Chunshun ^a   Hu, Haiyan ^a   Wu, Chuanbin ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GANNAN MEDICAL UNIVERSITY   (China)

^c GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Freeze drying; Hydrofluoroalkane; Nanoparticle; Pressurized metered dose inhaler; Protein and peptide; Tert butyl alcohol water co solvent

Indexed keywords

ALCOHOL; DIPALMITOYLPHOSPHATIDYLCHOLINE; FLUORINATED HYDROCARBON; LACTOSE; LYSOZYME; NANOPARTICLE; PHOSPHATIDYLCHOLINE; PROPELLANT; WATER;

ARTICLE; CENTRIFUGATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; FREEZE DRYING; LYOPHILISATE; METERED DOSE INHALER; NANOFABRICATION; NONHUMAN; PRIORITY JOURNAL; SUSPENSION; WATER CONTENT;

ADMINISTRATION, INHALATION; AEROSOL PROPELLANTS; ANTI-INFECTIVE AGENTS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; FREEZE DRYING; HYDROCARBONS, FLUORINATED; LACTOSE; LECITHINS; METERED DOSE INHALERS; MURAMIDASE; NANOPARTICLES; PARTICLE SIZE; PEPTIDES; PROTEINS; TERT-BUTYL ALCOHOL; WATER;

EID: 79958011283     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.069     Document Type: Article

References (29)

1. N. Anton, J.P. Benoit, and P. Saulnier Design and production of nanoparticles formulated from nano-emulsion templates - a review J. Control. Release 128 2008 185 199
2. Z. Antosova, M. Mackova, V. Kral, and T. Macek Therapeutic application of peptides and proteins: parenteral forever? Trends Biotechnol. 27 2009 628 635
3. M.M. Bailey, and C.J. Berkland Nanoparticle formulations in pulmonary drug delivery Med. Res. Rev. 29 2008 196 212
4. U. Bilati, E. Allemann, and E. Doelker Development of a nanoprecipitation method intended for the entrapment of hydrophilic drugs into nanoparticles Eur. J. Pharm. Sci. 24 2005 67 75 (Pubitemid 40051288)
5. R.O. Cook, R.K. Pannu, and I.W. Kellaway Novel sustained release microspheres for pulmonary drug delivery J. Control. Release 104 2005 79 90 (Pubitemid 40615237)
6. H. De Waard, W.L. Hinrichs, and H.W. Frijlink A novel bottom-up process to produce drug nanocrystals: controlled crystallization during freeze-drying J. Control. Release 128 2008 179 183
7. S.G. Dixit, A.R. Mahadeshwar, and S.K. Haram Some aspects of the role of surfactants in the formation of nanoparticles Colloids Surf. A: Physicochem. Eng. Aspects 133 1998 69 75 (Pubitemid 28157141)
8. FDA Guidance for Industry: Metered Dose Inhaler (MDI) and Dry Powder Inhaler (DPI) Drug Products - Chemistry, Manufacturing, and Controls Documentation 1998 US Department of Health and Human Services Rockville, IN
9. K. Kasraian, and P.P. DeLuca The effect of tertiary butyl alcohol on the resistance of the dry product layer during primary drying Pharm. Res. 12 1995 491 495
10. K. Kasraian, and P.P. DeLuca Thermal analysis of the tertiary butyl alcohol-water system and its implications on freeze-drying Pharm. Res. 12 1995 484 490
11. J.i. Lai, K.V.P.M. Shafi, A. Ulman, K. Loos, Y. Lee, T. Vogt, W.-L. Lee, N.P. Ong, and C. Estourns Controlling the size of magnetic nanoparticles using pluronic block copolymer surfactants J. Phys. Chem. B 109 2005 15 18 (Pubitemid 40120936)
12. H.Y. Li, and P.C. Seville Novel pMDI formulations for pulmonary delivery of proteins Int. J. Pharm. 385 2010 73 78
13. 2 nanoparticles with surfactants J. Photochem. Photobiol. A: Chem. 187 2007 363 369
14. Y.H. Liao, M.B. Brown, S.A. Jones, T. Nazir, and G.P. Martin The effects of polyvinyl alcohol on the in vitro stability and delivery of spray-dried protein particles from surfactant-free HFA 134a-based pressurised metered dose inhalers Int. J. Pharm. 304 2005 29 39 (Pubitemid 41427647)
15. Z. Liu, Z. Hu, J. Liang, S. Li, Y. Yang, S. Peng, and Y. Qian Size-controlled synthesis and growth mechanism of monodisperse tellurium nanorods by a surfactant-assisted method Langmuir 20 2004 214 218
16. B.K. Nyambura, I.W. Kellaway, and K.M.G. Taylor Insulin nanoparticles: stability and aerosolization from pressurized metered dose inhalers Int. J. Pharm. 375 2009 114 122
17. B.K. Nyambura, I.W. Kellaway, and K.M.G. Taylor The processing of nanoparticles containing protein for suspension in hydrofluoroalkane propellants Int. J. Pharm. 372 2009 140 146
18. M.P. Pileni The role of soft colloidal templates in controlling the size and shape of inorganic nanocrystals Nat. Mater. 2 2003 145 150
19. T. Purvis, M.E. Mattucci, M.T. Crisp, K.P. Johnston, and R.O. Williams 3rd Rapidly dissolving repaglinide powders produced by the ultra-rapid freezing process AAPS Pharmscitech 8 2007 E58
20. F. Qian, N. Ni, J.W. Chen, S. Desikan, V. Naringrekar, M.A. Hussain, N.P. Barbour, and R.L. Smith Formation of zinc-peptide spherical microparticles during lyophilization from tert-butyl alcohol/water co-solvent system Pharm. Res. 25 2008 2799 2806
21. E.A. Quinn, R.T. Forbes, A.C. Williams, M.J. Oliver, L. McKenzie, and T.S. Purewal Protein conformational stability in the hydrofluoroalkane propellants tetrafluoroethane and heptafluoropropane analysed by Fourier transform Raman spectroscopy Int. J. Pharm. 186 1999 31 41 (Pubitemid 29397520)
22. B.E. Rabinow Nanosuspensions in drug delivery Nat. Rev. Drug Discov. 3 2004 785 796 (Pubitemid 39242830)
23. S.a. Shoyele, and A. Slowey Prospects of formulating proteins/peptides as aerosols for pulmonary drug delivery Int. J. Pharm. 314 2006 1 8 (Pubitemid 44389384)
24. D.L. Teagarden, and D.S. Baker Practical aspects of lyophilization using non-aqueous co-solvent systems Eur. J. Pharm. Sci. 15 2002 115 133 (Pubitemid 34155373)
25. C. Terzano Pressurized metered dose inhalers and add-on devices Pulm. Pharmacol. Ther. 14 2001 351 366 (Pubitemid 32977018)
26. N. Tsapis, D. Bennett, B. Jackson, D.A. Weitz, and D.A. Edwards Trojan particles: large porous carriers of nanoparticles for drug delivery Proc. Natl. Acad. Sci. U.S.A. 99 2002 12001 12005
27. T. Wang, N. Wang, Y. Zhang, W. Shen, X. Gao, and T. Li Solvent injection-lyophilization of tert-butyl alcohol/water cosolvent systems for the preparation of drug-loaded solid lipid nanoparticles Colloids Surf. B: Biointerfaces 79 2010 254 261
28. R.O. Williams, and J. Liu Formulation of a protein with propellant HFA 134a for aerosol delivery Eur. J. Pharm. Sci. 7 1999 137 144 (Pubitemid 29056236)
29. Y. Zhang, Y. Deng, X. Wang, J. Xu, and Z. Li Conformational and bioactivity analysis of insulin: freeze-drying TBA/water co-solvent system in the presence of surfactant and sugar Int. J. Pharm. 371 2009 71 81