Contribution of chemokine CCL2/CCR2 signaling in the dorsal root ganglion and spinal cord to the maintenance of neuropathic pain in a rat model of lumbar disc herniation

Journal of Pain

Volumn 15, Issue 5, 2014, Pages 516-526

  Zhu, Xiang ^a   Cao, Su ^a   Zhu, Ming Di ^a   Liu, Jin Qian ^a   Chen, Jun Jie ^a   Gao, Yong Jing ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

astrocytes; chemokine C C motif ligand 2 (CCL2); chemokine C C motif receptor 2 (CCR2); Chemokines; lumber disc herniation; neuronal glial interaction

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR2 ANTAGONIST; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RS 504393; UNCLASSIFIED DRUG; ANALGESIC AGENT; BENZOXAZINE DERIVATIVE; CCL2 PROTEIN, RAT; CCR2 PROTEIN, RAT; SPIRO COMPOUND;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; HYPERSENSITIVITY; IMPLANTATION; LUMBAR DISK HERNIA; MACROPHAGE; MALE; MECHANICAL ALLODYNIA; NERVE CELL; NEUROPATHIC PAIN; NONHUMAN; NUCLEUS PULPOSUS; PROTEIN EXPRESSION; RAT; SPINAL CORD; SPINAL GANGLION; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; DRUG EFFECTS; HEAT; HYPERALGESIA; INTERVERTEBRAL DISK HERNIA; LUMBAR VERTEBRA; METABOLISM; NEURALGIA; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TOUCH;

ANALGESICS; ANIMALS; ASTROCYTES; BENZOXAZINES; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; HOT TEMPERATURE; HYPERALGESIA; INTERVERTEBRAL DISC DISPLACEMENT; LUMBAR VERTEBRAE; MACROPHAGES; MALE; NEURALGIA; NEURONS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CCR2; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPINAL CORD; SPIRO COMPOUNDS; TOUCH;

EID: 84899974730     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2014.01.492     Document Type: Article

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