Cytokine inhibition and time-related influence of inflammatory stimuli on the hyperalgesia induced by the nucleus pulposus

European Spine Journal

Volumn 21, Issue 3, 2012, Pages 537-545

  De Souza Grava, André Luiz ^a   Ferrari, Luiz Fernando ^a   Defino, Helton L A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Dorsal root ganglion; Hyperalgesia; Lumbar disc herniation; Radicular pain

Indexed keywords

ANTIBODY; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; INTERLEUKIN 10; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACK; CHRONIC PAIN; CONTROLLED STUDY; EELECTRONIC VON FREY; HYPERALGESIA; INFLAMMATORY HYPERALGESIA; INTERVERTEBRAL DISK HERNIA; LUMBAR SPINE; MALE; MECHANICAL HYPERALGESIA; MECHANICAL STIMULATION; NONHUMAN; NUCLEUS PULPOSUS; PAIN THRESHOLD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; SPINAL GANGLION; THERMAL HYPERALGESIA; THERMAL STIMULATION;

ANIMALS; ANTIBODIES; CHEMOKINE CXCL1; CYTOKINES; HYPERALGESIA; INFLAMMATION MEDIATORS; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERVERTEBRAL DISC; MALE; RATS; RATS, WISTAR; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862836025     PISSN: 09406719     EISSN: 14320932     Source Type: Journal    
DOI: 10.1007/s00586-011-2027-8     Document Type: Article

References (39)

1. Kawakami M, Tamaki T, Matsumoto T, Kuribayashi K, Take-naka T, Shinozaki M (2000) Role of leukocytes in radicular pain secondary to herniated nucleus pulposus. Clin Orthop Relat Res 376:268-277 (Pubitemid 30445704)
2. Olmarker K, Nordborg C, Larsson K, Rydevik B (1996) Ultra-structural changes in spinal nerve roots induced by autologous nucleus pulposus. Spine (Phila Pa 1976) 21:411-414 (Pubitemid 26067847)
3. Byrod G, Rydevik B, Nordborg C, Olmarker K (1998) Early effects of nucleus pulposus application on spinal nerve root morphology and function. Eur Spine J 7:445-449 (Pubitemid 29009740)
4. Kayama S, Konno S, Olmarker K, Yabuki S, Kikuchi S (1996) Incision of the anulus fibrosus induces nerve root morphologic, vascular, and functional changes. An experimental study. Spine 21:2539-2543 (Pubitemid 26419089)
5. Olmarker K, Rydevik B, Nordborg C (1993) Autologous nucleus pulposus induces neurophysiologic and histologic changes in porcine cauda equina nerve roots. Spine 18:1425-1432 (Pubitemid 23270905)
6. Yabuki S, Kikuchi S, Olmarker K, Myers RR (1998) Acute effects of nucleus pulposus on blood flow and endoneurial fluid pressure in rat dorsal root ganglia. Spine 23:2517-2523 (Pubitemid 29003525)
7. Olmarker K, Brisby H, Yabuki S, Nordborg C, Rydevik B (1997) The effects of normal, frozen, and hyaluronidase-digested nucleus pulposus on nerve root structure and function. Spine (Phila Pa 1976) 22:471-475
8. Kang JD, Georgescu HI, McIntyre-Larkin L, Stefanovic-Racic M, Donaldson WF III, Evans CH (1996) Herniated lumbar intervertebral discs spontaneously produce matrix metallopro-teinases, nitric oxide, interleukin-6, and prostaglandin E2. Spine (Phila Pa 1976) 21:271-277 (Pubitemid 26056478)
9. Kayama S, Olmarker K, Larsson K, Sjogren-Jansson E, Lindahl A, Rydevik B (1998) Cultured, autologous nucleus pulposus cells induce functional changes in spinal nerve roots. Spine (Phila Pa 1976) 23:2155-2158 (Pubitemid 28485167)
10. Brisby H, Byrod G, Olmarker K, Miller VM, Aoki Y, Rydevik B (2000) Nitric oxide as a mediator of nucleus pulposus-induced effects on spinal nerve roots. J Orthop Res 18:815-820
11. Nachemson A (1969) Intradiscal measurements of pH in patients with lumbar rhizopathies. Acta Orthop Scand 40:23-42
12. Naylor A (1962) The biophysical and biochemical aspects of intervertebral disc herniation and degeneration. Ann Roy Coll Surg Engl 31:91-114
13. Pennington JB, McCarron RF, Laros GS (1988)IdentificationofIgG in the canine intervertebral disc. Spine (Phila Pa 1976) 13:909-912
14. Saal JS, Franson RC, Dobrow R, Saal JA, White AH, Gold-thwaite N (1990) High levels ofinflammatory phospholipase A2 activity in lumbar disc herniations. Spine (Phila Pa 1976) 15:674-678 (Pubitemid 20264755)
15. Schaible HG, Schmidt RF (1996) Neurophysiology of chronic inflammatory pain: electrophysiological recordings from spinal cord neurons in rats with prolonged acute and chronic unilateral inflammation at the ankle. Prog Brain Res 110:167-176 (Pubitemid 27048986)
16. Willis WD, Westlund KN (1997) Neuroanatomy of the pain system and of the pathways that modulate pain. J Clin Neuro-physiol 14:2-31 (Pubitemid 27220502)
17. Takahashi H, Suguro T, Okazima Y, Motegi M, Okada Y, Kakiuchi T (1996) Inflammatory cytokines in the herniated disc of the lumbar spine. Spine (Phila Pa 1976) 21:218-224 (Pubitemid 26041220)
18. Igarashi T, Kikuchi S, Shubayev V, Myers RR (2000) 2000 Volvo Award winner in basic science studies: exogenous tumor necrosis factor-alpha mimics nucleus pulposus-induced neuro-pathology. Molecular, histologic, and behavioral comparisons in rats. Spine (Phila Pa 1976) 25:2975-2980
19. Olmarker K, Nutu M, Storkson R (2003) Changes in spontaneous behavior in rats exposed to experimental disc herniation are blocked by selective TNF-alpha inhibition. Spine 28:1635-1641 (Pubitemid 36961069)
20. Rand N, Reichert F, Floman Y, Rotshenker S (1997) Murine nucleus pulposus-derived cells secrete interleukins-1-beta, -6, and -10 and granulocyte-macrophage colony-stimulating factor in cell culture. Spine (Phila Pa 1976) 22:2598-2601
21. Peng B, Wu W, Li Z, Guo J, Wang X (2007) Chemical radiculitis. Pain 127:11-16 (Pubitemid 44959427)
22. Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ (2001) Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410:471-475 (Pubitemid 32240046)
23. Vivancos GG, Verri WA Jr, Cunha TM, Schivo IR, Parada CA, Cunha FQ, Ferreira SH (2004) An electronic pressure-meter nociception paw test for rats. Braz J Med Biol Res 37:391-399 (Pubitemid 38444530)
24. Hargreaves K, Dubner R, Brown F, Flores C, Joris J (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88
25. Safieh-Garabedian B, Poole S, Allchorne A, Winter J, Woolf CJ (1995) Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br J Pharmacol 115:1265-1275
26. Murata Y, Onda A, Rydevik B, Takahashi K, Olmarker K (2004) Distribution and appearance of tumor necrosis factor-alpha in dorsal root ganglion exposure to experimental disc herniation in rats. Spine 29(20):2235-2241 (Pubitemid 40362217)
27. Rand N, Reichert F, Floman Y, Rotsshenker S (1997) Murine nucleus pulposus-derived cells secrete interleukins-1-(beta),-6 and -10 and granulocyte-macrophage colony-stimulating factor in cell culture. Spine 22(22):2598-2601
28. Sinclair SM, Shamji MF, Jing L, Richardson WJ, Brown CR, Fitch RD, Setton LA (2011) Attenuation of inflammatory events in human intervertebral disc cells with a tumor necrosis factor antagonist. Spine 36(13):1190-1196
29. Bruck W, Bruck Y, Maruschak B, Friede RL (1995) Mechanisms of macrophage recruitment in Wallerian degeneration. Acta Neuropathol 89:363-367
30. Olsson Y, Sjostrand J (1969) Origin of macrophages in Wallerian degeneration of peripheral nerves demonstrated autoradiograph-ically. Exp Neurol 23:102-112
31. Burke JG, Watson RW, McCormack D, Dowling FE, Walsh MG, Fitzpatrick JM (2002) Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators. J Bone Joint Surg Br 84:196-201 (Pubitemid 34257682)
32. Omarker K, Myers RR (1998) Pathogenesis of sciatic pain: role of herniated nucleus pulposus and deformation of spinal nerve root and dorsal root ganglion. Pain 78:99-105 (Pubitemid 28517947)
33. Weiler C, Nerlich AG, Bachmeier BE, Boos N (2005) Expression and distribution of tumor necrosis factor alpha in human lumbar intervertebral discs: a study in surgical specimen and autopsy controls. Spine (Phila Pa 1976) 30:44-53 (Pubitemid 40209276)
34. Hayashi Y, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Su-zuki M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Fukui Y, Wakai K, Kuniyoshi K, Ishikawa T, Arai G, Miyagi M, Ka-moda H, Aoki Y, Takahashi K (2009) Direct single injection of p38 mitogen-activated protein kinase inhibitor does not affect calcitonin gene-related peptide expression in dorsal root ganglion neurons innervating punctured discs in rats. Spine (Phila Pa 1976) 34:2843-2847
35. Studer RK, Aboka AM, Gilbertson LG, Georgescu H, Sowa G, Vo N, Kang JD (2007) p38 MAPK inhibition in nucleus pulposus cells: a potential target for treating intervertebral disc degenera-tion. Spine (Phila Pa 1976) 32:2827-2833 (Pubitemid 351339352)
36. Julius D, Basbaum AI (2001) Molecular mechanisms of noci-ception. Nature 413:203-210
37. Woolf CJ, Ma Q (2007) Nociceptors-noxious stimulus detectors. Neuron 55:353-364 (Pubitemid 47126273)
38. Gibson JN, Waddell G (2007) Surgical interventions for lumbar disc prolapse. Cochrane Database Syst Rev CD001350
39. Fritzell P, Stromquist, Jönsson B, Hägg O (2011) Prediction of outcome after surgery for lumbar disc herniation in Sweden. Analysis of data from Swespie-The National Register. Annals of 38th ISSLS annual meeting. Gothenburg, Sweden, p 50