Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery

Journal of Cerebral Blood Flow and Metabolism

Volumn 34, Issue 5, 2014, Pages 897-905

  Manzanero, Silvia ^a   Erion, Joanna R ^b   Santro, Tomislav ^a   Steyn, Frederik J ^a   Chen, Chen ^a   Arumugam, Thiruma V ^a,c   Stranahan, Alexis M ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

caloric restriction; hippocampus; intermittent fasting; neurogenesis; stroke; subventricular zone

Indexed keywords

LEPTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL CELL; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN PERFUSION; CALORIC RESTRICTION; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DIET RESTRICTION; FOOD INTAKE; HIPPOCAMPUS; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REPERFUSION INJURY; SUBVENTRICULAR ZONE;

ANIMALS; CELL DEATH; CELL PROLIFERATION; FASTING; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; LEPTIN; MALE; MICE; MICE, INBRED C57BL; NEUROGENESIS; NEURONS; WEIGHT LOSS;

EID: 84899956587     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.36     Document Type: Article

References (20)

1. Stranahan AM, Mattson MP. Recruiting adaptive cellular stress responses for successful brain ageing. Nat Rev Neurosci 2012; 13: 209-216.
2. Lichtenwalner RJ, Parent JM. Adult neurogenesis and the ischemic forebrain. J Cereb Blood Flow Metab 2006; 26: 1-20.
3. Murphy TH, Corbett D. Plasticity during stroke recovery: from synapse to behaviour. Nat Rev Neurosci 2009; 10: 861-872.
4. Niv F, Keiner S, Krishna, Witte OW, Lie DC, Redecker C. Aberrant neurogenesis after stroke: a retroviral cell labeling study. Stroke 2012; 43: 2468-2475.
5. Stranahan AM, Khalil D, Gould E. Social isolation delays the positive effects of running on adult neurogenesis. Nat Neurosci 2006; 9: 526-533.
6. Lee J, Duan W, Mattson MP. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem 2002; 82: 1367-1375.
7. Aimone JB, Wiles J, Gage FH. Computational influence of adult neurogenesis on memory encoding. Neuron 2009; 61: 187-202.
8. Wang Z, Andrade N, Torp M, Wattananit S, Arvidsson A, Kokaia Z et al. Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis. J Cereb Blood Flow Metab 2012; 32: 387-398.
9. Arumugam TV, Phillips TM, Cheng A, Morrell CH, Mattson MP, Wan R. Age and energy intake interact to modify cell stress pathways and stroke outcome. Ann Neurol 2010; 67: 41-52.
10. Garza JC, Guo M, Zhang W, Lu XY. Leptin increases adult hippocampal neurogenesis in vivo and in vitro. J Biol Chem 2008; 283: 18238-18247.
11. Jin K, Minami M, Lan JQ, Mao XO, Batteur S, Simon RP et al. Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci USA 2001; 98: 4710-4715.
12. Cameron HA, McKay RD. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 2001; 435: 406-417.
13. Stranahan AM, Arumugam TV, Cutler RG, Lee K, Egan JM, Mattson MP. Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nat Neurosci 2008; 11: 309-317.
14. Stranahan AM, Jiam NT, Spiegel AM, Gallagher M. Aging reduces total neuron number in the dorsal component of the rodent prefrontal cortex. J Comp Neurol 2012; 520: 1318-1326.
15. Anson RM, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A et al. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc Natl Acad Sci USA 2003; 100: 6216-6220.
16. Zhang F, Wang S, Signore AP, Chen J. Neuroprotective effects of leptin against ischemic injury induced by oxygen-glucose deprivation and transient cerebral ischemia. Stroke 2007; 38: 2329-2336.
17. Zhang J, Deng Z, Liao J, Song C, Liang C, Xue H et al. Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the pi3k/akt pathway. J Cereb Blood Flow Metab 2013; 33: 567-574.
18. Vannucci SJ, Willing LB, Goto S, Alkayed NJ, Brucklacher RM, Wood TL et al. Experimental stroke in the female diabetic, db/db, mouse. J Cereb Blood Flow Metab 2001; 21: 52-60.
19. Zhang RL, Zhang ZG, Zhang L, Chopp M. Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia. Neuroscience 2001; 105: 33-41.
20. Lee J, Duan W, Long JM, Ingram DK, Mattson MP. Dietary restriction increases the number of newly generated neural cells, and induces bdnf expression, in the dentate gyrus of rats. J Mol Neurosci 2000; 15: 99-108.