Aberrant neurogenesis after stroke: A retroviral cell labeling study

Stroke

Volumn 43, Issue 9, 2012, Pages 2468-2475

  Niv, Fanny ^a   Keiner, Silke ^a   Krishna K, ^a   Witte, Otto W ^a   Lie, Dieter Chichung ^b,c   Redecker, Christoph ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

adult neurogenesis; dentate gyrus; photothrombosis; plasticity; retroviral vectors

Indexed keywords

GREEN FLUORESCENT PROTEIN; RETROVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; CELL LABELING; CELL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; GRANULE CELL; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PHOTOTHROMBOSIS; PRIORITY JOURNAL; RAT; STROKE; THROMBOSIS; VOLUMETRY;

ANIMALS; BRAIN ISCHEMIA; CYTOPLASMIC GRANULES; DENDRITES; DENDRITIC SPINES; DENTATE GYRUS; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; INFARCTION, MIDDLE CEREBRAL ARTERY; INTRACRANIAL THROMBOSIS; LUMINESCENT PROTEINS; MALE; NEUROGENESIS; NEURONAL PLASTICITY; NEURONS; RATS; RATS, WISTAR; RETROVIRIDAE; STROKE;

EID: 84865601530     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.660977     Document Type: Article

References (26)

1. Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell. 2008;132:645-660.
2. van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH. Functional neurogenesis in the adult hippocampus. Nature. 2002;415: 1030-1034.
3. Laplagne DA, Espósito MS, Piatti VC, Morgenstern NA, Zhao C, van Praag H, et al. Functional convergence of neurons generated in the developing and adult hippocampus. PloS Biol. 2006;4:2349-2360.
4. Liu J, Solway K, Messing RO, Sharp FR. Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils. J Neurosci. 1998;18:7768-7778.
5. Kernie SG, Parent JM. Forebrain neurogenesis after focal ischemic and traumatic brain injury. Neurol Biol Dis. 2010;37:267-274.
6. Arvidsson A, Kokaia Z, Lindvall O. N-methyl-D-aspartate receptor-mediated increase of neurogenesis in adult rat dentate gyrus following stroke. Eur J Neurosci. 2001;14:10-18.
7. Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS, Low-enstein DH. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci. 1997;17:3727-3738.
8. Jessberger S, Nakashima K, Clemenson GD Jr, Mejia E, Mathews E, Ure K, et al. Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. J Neurosci. 2007;27:5967-5975.
9. Walter C, Murphy BL, Pun RY, Spieles-Engemann AL, Danzer SC. Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells. J Neurosci. 2007;27: 7541-7552.
10. Jessberger S, Zhao C, Toni N, Clemenson GD Jr, Li Y Gage FH. Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling. J Neurosci. 2007;27:9400-9407.
11. Kron MM, Zhang H, Parent JM. The developmental stage of dentate granule cells dictates their contribution to seizure-induced plasticity. J Neurosci. 2010;30:2051-2059.
12. Ribak CE, Tran PH, Spigelman I, Okazaki MM, Nadler JV. Status epilepticus-induced hilar basal dendrites on rodent granule cells contribute to recurrent excitatory circuitry. J Comp Neurol. 2000;428: 240-253.
13. Thind KK, Ribak CE, Buckmaster PS. Synaptic input to dentate granule cell basal dendrites in a rat model of temporal lobe epilepsy. J Comp Neurol. 2008;509:190-202.
14. Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, Saxe M, et al. GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. J Neurosci. 2009;29:7966-7977.
15. Tashiro A, Zhao C, Gage FH. Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo. Nat Protocols. 2006;1:3049-3055.
16. Kluska MM, Witte OW, Bolz J, Redecker C. Neurogenesis in the adult dentate gyrus after cortical infarcts: effects of infarct location, NMDA receptor blockade and anti-inflammatory treatment. Neuroscience. 2005; 135:723-735.
17. Toni N, Teng EM, Bushong EA, Aimone JB, Zhao C, Consiglio A, et al. Synapse formation on neurons born in the adult hippocampus. Nat Neurosci. 2007;10:727-734.
18. Paxinos G, Watson C. The Rats in the Stereotaxic Coordinates. New York, NY: Academic Press; 1986.
19. Zhao C, Teng EM, Summers RG Jr, Ming GL, Gage FH. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J Neurosci. 2006;26:3-11.
20. Toni N, Sultan S. Synapse formation on adult-born hippocampal neurons. Eur J Neurosci. 2011;33:1062-1068.
21. Ge S, Goh EL, Sailor KA, Kitabatake Y, Ming GL, Song H. GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature. 2006;439:589-593.
22. Shapiro LA, Ribak CE, Jessberger S. Structural changes for adult-born dentate granule cells after status epilepticus. Epilepsia. 2008;49(suppl 5): 13-18.
23. Jakubs K, Nanobashvili A, Bonde S, Ekdahl CT, Kokaia Z, Kokaia M, et al. Environment matters: synaptic properties of neurons born in the epileptic adult brain develep to reduce excitability. Neuron. 2006;52: 1047-1059.
24. Wood JC, Jackson JS, Jakubs K, Chapman KZ, Ekdahl CT, et al. Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment. Exp Neurol. 2011;229:484-493.
25. Wurm F, Keiner S, Kunze A, Witte OW, Redecker C. Effects of skilled forelimb training on hippocampal neurogenesis and spatial learning after focal cortical infarcts in the adult rat brain. Stroke. 2007;38:2833-2840.
26. Zhao C, Wang J, Zhao S, Nie Y. Constraint-induced movement therapy enhanced neurogenesis and behavioral recovery after stroke in adult rats. Tohoku J Exp Med. 2009;218:301-308.