Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the PI 3 K/Akt pathway

Journal of Cerebral Blood Flow and Metabolism

Volumn 33, Issue 4, 2013, Pages 567-574

  Zhang, Jinying ^a   Deng, Zihui ^a   Liao, Jie ^a   Song, Cuihong ^a   Liang, Chen ^a   Xue, Hui ^a   Wang, Luhuan ^a   Zhang, Kai ^a   Yan, Guangtao ^a  

^a Department of Surgery   (China)

Author keywords

Akt pathway; cerebral ischemia; energy metabolism; leptin; neuroprotection; PI3K; reperfusion; stroke

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATE; LACTATE DEHYDROGENASE; LACTIC ACID; LEPTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PYRUVATE CARBOXYLASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENERGY METABOLISM; GLUCOSE TRANSPORT; HISTOPATHOLOGY; MOUSE; NERVE CELL CULTURE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN EDEMA; BRAIN INFARCTION; CHROMONES; ENERGY METABOLISM; ENZYME INHIBITORS; L-LACTATE DEHYDROGENASE; LACTIC ACID; LEPTIN; MALE; MICE; MORPHOLINES; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PYRUVIC ACID; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 84876407451     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2012.202     Document Type: Article

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