Dose-and time-dependent epigenetic changes in the livers of fisher 344 rats exposed to furan

Toxicological Sciences

Volumn 139, Issue 2, 2014, Pages 371-380

  de Conti, Aline ^a   Kobets, Tetyana ^a   Escudero Lourdes, Claudia ^a,b   Montgomery, Beverly ^a   Tryndyak, Volodymyr ^a   Beland, Frederick Alan ^a   Doerge, Daniel R ^a   Pogribny, Igor Petrovych ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

Author keywords

Epigenetic changes; Furan; Liver; Rat

Indexed keywords

FURAN; HISTONE ACETYLTRANSFERASE; HISTONE H3; HISTONE H4; HISTONE METHYLTRANSFERASE; LYSINE; LYSINE 20; LYSINE 56; LYSINE 9; UNCLASSIFIED DRUG; FURAN DERIVATIVE; HISTONE LYSINE METHYLTRANSFERASE; POLLUTANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CHROMATIN; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; GENE; GENE EXPRESSION; HISTONE ACETYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; LIVER; LIVER TOXICITY; LONG TERM EXPOSURE; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; FISCHER 344 RAT; GENETIC EPIGENESIS; GENETICS; METABOLISM; POLLUTANT; TIME; TOXICITY;

ANIMALS; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EPIGENESIS, GENETIC; FURANS; HISTONE-LYSINE N-METHYLTRANSFERASE; LIVER; MALE; RATS, INBRED F344; TIME FACTORS;

EID: 84899944265     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu044     Document Type: Article

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