Integrin αv in the mechanical response of osteoblast lineage cells

Biochemical and Biophysical Research Communications

Volumn 447, Issue 2, 2014, Pages 352-357

  Kaneko, Keiko ^a   Ito, Masako ^b   Naoe, Yoshinori ^a   Lacy Hulbert, Adam ^c   Ikeda, Kyoji ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b NAGASAKI UNIVERSITY HOSPITAL   (Japan)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Integrin v; Mechanotransduction; Osteoblast; p130Cas; YAP TAZ

Indexed keywords

CD51 ANTIGEN; SHORT HAIRPIN RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL LINEAGE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MECHANICAL STIMULATION; MECHANORECEPTOR; MECHANOTRANSDUCTION; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SHEAR STRESS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSMISSION ELECTRON MICROSCOPY;

INTEGRIN ΑV; MECHANOTRANSDUCTION; OSTEOBLAST; P130CAS; YAP/TAZ;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINEAGE; CELLS, CULTURED; INTEGRIN ALPHAV; MAP KINASE KINASE 4; MECHANOTRANSDUCTION, CELLULAR; MICE; OSTEOBLASTS; PHOSPHOPROTEINS; SHEAR STRENGTH; SRC-FAMILY KINASES; STRESS, MECHANICAL; TRANSCRIPTION FACTORS;

EID: 84899936827     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.04.006     Document Type: Article

References (31)

1. M. Zaidi Skeletal remodeling in health and disease Nat. Med. 13 2007 791 801
2. L.F. Bonewald, and M.L. Johnson Osteocytes, mechanosensing and Wnt signaling Bone 42 2008 606 615
3. S. Tatsumi, K. Ishii, N. Amizuka, M. Li, T. Kobayashi, K. Kohno, M. Ito, S. Takeshita, and K. Ikeda Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction Cell Metab. 5 2007 464 475
4. L.F. Bonewald The amazing osteocyte J. Bone Miner. Res. 26 2011 229 238
5. J. Klein-Nulend, A.D. Bakker, R.G. Bacabac, A. Vatsa, and S. Weinbaum Mechanosensation and transduction in osteocytes Bone 54 2013 182 190
6. R.O. Hynes Integrins: bidirectional, allosteric signaling machines Cell 110 2002 673 687
7. A. Katsumi, A.W. Orr, E. Tzima, and M.A. Schwartz Integrins in mechanotransduction J. Biol. Chem. 279 2004 12001 12004
8. S. Weinbaum, Y. Duan, M.M. Thi, and L. You An integrative review of mechanotransduction in endothelial, epithelial (renal) and dendritic cells (osteocytes) Cell Mol. Bioeng. 4 2011 510 537
9. L.I. Plotkin, I. Mathov, J.I. Aguirre, A.M. Parfitt, S.C. Manolagas, and T. Bellido Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs Am. J. Physiol. Cell Physiol. 289 2005 C633 C643
10. A. Miyauchi, M. Gotoh, H. Kamioka, K. Notoya, H. Sekiya, Y. Takagi, Y. Yoshimoto, H. Ishikawa, K. Chihara, T. Takano-Yamamoto, T. Fujita, and Y. Mikuni-Takagaki AlphaVbeta3 integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes J. Bone Miner. Metab. 24 2006 498 504
11. A. Lacy-Hulbert, A.M. Smith, H. Tissire, M. Barry, D. Crowley, R.T. Bronson, J.T. Roes, J.S. Savill, and R.O. Hynes Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins Proc. Natl. Acad. Sci. USA 104 2007 15823 15828
12. Y. Sawada, M. Tamada, B.J. Dubin-Thaler, O. Cherniavskaya, R. Sakai, S. Tanaka, and M.P. Sheetz Force sensing by mechanical extension of the Src family kinase substrate p130Cas Cell 127 2006 1015 1026
13. J.H. McCarty, A. Lacy-Hulbert, A. Charest, R.T. Bronson, D. Crowley, D. Housman, J. Savill, J. Roes, and R.O. Hynes Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death Development 132 2005 165 176
14. S.J. Rodda, and A.P. McMahon Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors Development 133 2006 3231 3244
15. P. Soriano, C. Montgomery, R. Geske, and A. Bradley Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice Cell 64 1991 693 702
16. A.G. Robling, P.J. Niziolek, L.A. Baldridge, K.W. Condon, M.R. Allen, I. Alam, S.M. Mantila, J. Gluhak-Heinrich, T.M. Bellido, S.E. Harris, and C.H. Turner Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin J. Biol. Chem. 283 2008 5866 5875
17. T. Ogata Egr-1 mRNA induction by medium flow involves mRNA stabilization and is enhanced by the p38 inhibitor SB203580 in osteoblast-like cells Acta Physiol. (Oxf.) 194 2008 177 188
18. H. Ogawa, E. Kozhemyakina, H.H. Hung, A.J. Grodzinsky, and A.B. Lassar Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways Genes Dev. 28 2014 127 139
19. T. Fumoto, S. Takeshita, M. Ito, and K. Ikeda Physiological functions of osteoblast lineage and T cell-derived RANKL in bone homeostasis J. Bone Miner. Res. 29 2014 830 842
20. M. Hughes-Fulford Signal transduction and mechanical stress Sci. STKE 2004
21. M. Tamada, M.P. Sheetz, and Y. Sawada Activation of a signaling cascade by cytoskeleton stretch Dev. Cell 7 2004 709 718
22. S. Dupont, L. Morsut, M. Aragona, E. Enzo, S. Giulitti, M. Cordenonsi, F. Zanconato, J. Le Digabel, M. Forcato, S. Bicciato, N. Elvassore, and S. Piccolo Role of YAP/TAZ in mechanotransduction Nature 474 2011 179 183
23. H. Rangaswami, R. Schwappacher, N. Marathe, S. Zhuang, D.E. Casteel, B. Haas, Y. Chen, A. Pfeifer, H. Kato, S. Shattil, G.R. Boss, and R.B. Pilz Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts Sci. Signal 3 2010 (ra91)
24. C. Lin, X. Jiang, Z. Dai, X. Guo, T. Weng, J. Wang, Y. Li, G. Feng, X. Gao, and L. He Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling J. Bone Miner. Res. 24 2009 1651 1661
25. L.M. McNamara, R.J. Majeska, S. Weinbaum, V. Friedrich, and M.B. Schaffler Attachment of osteocyte cell processes to the bone matrix Anat. Rec. (Hoboken) 292 2009 355 363
26. G. Halder, and R.L. Johnson Hippo signaling: growth control and beyond Development 138 2011 9 22
27. B. Zhao, X. Ye, J. Yu, L. Li, W. Li, S. Li, J. Yu, J.D. Lin, C.Y. Wang, A.M. Chinnaiyan, Z.C. Lai, and K.L. Guan TEAD mediates YAP-dependent gene induction and growth control Genes Dev. 22 2008 1962 1971
28. S.K. Zaidi, A.J. Sullivan, R. Medina, Y. Ito, A.J. van Wijnen, J.L. Stein, J.B. Lian, and G.S. Stein Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription EMBO J. 23 2004 790 799
29. J.H. Hong, E.S. Hwang, M.T. McManus, A. Amsterdam, Y. Tian, R. Kalmukova, E. Mueller, T. Benjamin, B.M. Spiegelman, P.A. Sharp, N. Hopkins, and M.B. Yaffe TAZ, a transcriptional modulator of mesenchymal stem cell differentiation Science 309 2005 1074 1078
30. Y. Tang, R.G. Rowe, E.L. Botvinick, A. Kurup, A.J. Putnam, M. Seiki, V.M. Weaver, E.T. Keller, S. Goldstein, J. Dai, D. Begun, T. Saunders, and S.J. Weiss MT1-MMP-dependent control of skeletal stem cell commitment via a beta1-Integrin/YAP/TAZ signaling axis Dev. Cell 25 2013 402 416
31. F. Calvo, N. Ege, A. Grande-Garcia, S. Hooper, R.P. Jenkins, S.I. Chaudhry, K. Harrington, P. Williamson, E. Moeendarbary, G. Charras, and E. Sahai Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts Nat. Cell Biol. 15 2013 637 646