메뉴 건너뛰기




Volumn 186, Issue 2, 2014, Pages 308-317

The structure of AAVrh32.33, a novel gene delivery vector

Author keywords

AAVrh32.33; Adeno associated virus; Gene therapy; Parvovirus; Virus capsid structure; X ray crystallography

Indexed keywords

VIRUS PROTEIN;

EID: 84899928403     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2014.03.020     Document Type: Article
Times cited : (31)

References (62)
  • 1
    • 84859440283 scopus 로고    scopus 로고
    • The AAV vector toolkit: poised at the clinical crossroads
    • Asokan A., Schaffer D.V., Samulski R.J. The AAV vector toolkit: poised at the clinical crossroads. Mol. Ther. 2012, 20:699-708.
    • (2012) Mol. Ther. , vol.20 , pp. 699-708
    • Asokan, A.1    Schaffer, D.V.2    Samulski, R.J.3
  • 2
    • 77954976233 scopus 로고    scopus 로고
    • Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors
    • Boutin S., Monteilhet V., Veron P., Leborgne C., Benveniste O., Montus M.F., Masurier C. Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors. Hum. Gene Ther. 2010, 21:704-712.
    • (2010) Hum. Gene Ther. , vol.21 , pp. 704-712
    • Boutin, S.1    Monteilhet, V.2    Veron, P.3    Leborgne, C.4    Benveniste, O.5    Montus, M.F.6    Masurier, C.7
  • 4
    • 0017800252 scopus 로고
    • Characterization of adenovirus-associated virus-induced polypeptides in KB cells
    • Buller R.M., Rose J.A. Characterization of adenovirus-associated virus-induced polypeptides in KB cells. J. Virol. 1978, 25:331-338.
    • (1978) J. Virol. , vol.25 , pp. 331-338
    • Buller, R.M.1    Rose, J.A.2
  • 5
    • 58849086758 scopus 로고    scopus 로고
    • Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses
    • Calcedo R., Vandenberghe L.H., Gao G., Lin J., Wilson J.M. Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses. J. Infect. Dis. 2009, 199:381-390.
    • (2009) J. Infect. Dis. , vol.199 , pp. 381-390
    • Calcedo, R.1    Vandenberghe, L.H.2    Gao, G.3    Lin, J.4    Wilson, J.M.5
  • 6
    • 85145134354 scopus 로고    scopus 로고
    • Atomic structure of viral particles
    • Hodder Arnold, London, J.R. Kerr, S.F. Cotmore, M.E. Bloom, R.M. Linden, C.R. Parrish (Eds.)
    • Chapman M.S., Agbandje-Mckenna M. Atomic structure of viral particles. Parvoviruses 2006, 107-123. Hodder Arnold, London. J.R. Kerr, S.F. Cotmore, M.E. Bloom, R.M. Linden, C.R. Parrish (Eds.).
    • (2006) Parvoviruses , pp. 107-123
    • Chapman, M.S.1    Agbandje-Mckenna, M.2
  • 9
    • 13244281317 scopus 로고    scopus 로고
    • Coot: model-building tools for molecular graphics
    • Emsley P., Cowtan K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D 2004, 60:2126-2132.
    • (2004) Acta Crystallogr. D , vol.60 , pp. 2126-2132
    • Emsley, P.1    Cowtan, K.2
  • 15
    • 33646719922 scopus 로고    scopus 로고
    • Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly
    • Grieger J.C., Snowdy S., Samulski R.J. Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly. J. Virol. 2006, 80:5199-5210.
    • (2006) J. Virol. , vol.80 , pp. 5199-5210
    • Grieger, J.C.1    Snowdy, S.2    Samulski, R.J.3
  • 19
    • 0346147026 scopus 로고    scopus 로고
    • Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies
    • Huttner N.A., Girod A., Perabo L., Edbauer D., Kleinschmidt J.A., Buning H., Hallek M. Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies. Gene Ther. 2003, 10:2139-2147.
    • (2003) Gene Ther. , vol.10 , pp. 2139-2147
    • Huttner, N.A.1    Girod, A.2    Perabo, L.3    Edbauer, D.4    Kleinschmidt, J.A.5    Buning, H.6    Hallek, M.7
  • 20
    • 0015193563 scopus 로고
    • Structural proteins of adenovirus-associated virus type 3
    • Johnson F.B., Ozer H.L., Hoggan M.D. Structural proteins of adenovirus-associated virus type 3. J. Virol. 1971, 8:860-863.
    • (1971) J. Virol. , vol.8 , pp. 860-863
    • Johnson, F.B.1    Ozer, H.L.2    Hoggan, M.D.3
  • 22
    • 13444307044 scopus 로고    scopus 로고
    • Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
    • Krissinel E., Henrick K. Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr. D 2004, 60:2256-2268.
    • (2004) Acta Crystallogr. D , vol.60 , pp. 2256-2268
    • Krissinel, E.1    Henrick, K.2
  • 23
    • 0030339738 scopus 로고    scopus 로고
    • AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR
    • Laskowski R.A., Rullmannn J.A., MacArthur M.W., Kaptein R., Thornton J.M. AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR. J. Biomol. NMR 1996, 8:477-486.
    • (1996) J. Biomol. NMR , vol.8 , pp. 477-486
    • Laskowski, R.A.1    Rullmannn, J.A.2    MacArthur, M.W.3    Kaptein, R.4    Thornton, J.M.5
  • 24
    • 77953285729 scopus 로고    scopus 로고
    • The structure of adeno-associated virus serotype 3B (AAV-3B): insights into receptor binding and immune evasion
    • Lerch T.F., Xie Q., Chapman M.S. The structure of adeno-associated virus serotype 3B (AAV-3B): insights into receptor binding and immune evasion. Virology 2010, 403:26-36.
    • (2010) Virology , vol.403 , pp. 26-36
    • Lerch, T.F.1    Xie, Q.2    Chapman, M.S.3
  • 27
    • 72849118242 scopus 로고    scopus 로고
    • A new genetic vaccine platform based on an adeno-associated virus isolated from a rhesus macaque
    • Lin J., Calcedo R., Vandenberghe L.H., Bell P., Somanathan S., Wilson J.M. A new genetic vaccine platform based on an adeno-associated virus isolated from a rhesus macaque. J. Virol. 2009, 83:12738-12750.
    • (2009) J. Virol. , vol.83 , pp. 12738-12750
    • Lin, J.1    Calcedo, R.2    Vandenberghe, L.H.3    Bell, P.4    Somanathan, S.5    Wilson, J.M.6
  • 28
    • 30344450073 scopus 로고    scopus 로고
    • Mutations on the external surfaces of adeno-associated virus type 2 capsids that affect transduction and neutralization
    • Lochrie M.A., Tatsuno G.P., Christie B., McDonnell J.W., Zhou S., Surosky R., Pierce G.F., Colosi P. Mutations on the external surfaces of adeno-associated virus type 2 capsids that affect transduction and neutralization. J. Virol. 2006, 80:821-834.
    • (2006) J. Virol. , vol.80 , pp. 821-834
    • Lochrie, M.A.1    Tatsuno, G.P.2    Christie, B.3    McDonnell, J.W.4    Zhou, S.5    Surosky, R.6    Pierce, G.F.7    Colosi, P.8
  • 30
    • 32344438754 scopus 로고    scopus 로고
    • Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
    • Maheshri N., Koerber J.T., Kaspar B.K., Schaffer D.V. Directed evolution of adeno-associated virus yields enhanced gene delivery vectors. Nat. Biotechnol. 2006, 24:198-204.
    • (2006) Nat. Biotechnol. , vol.24 , pp. 198-204
    • Maheshri, N.1    Koerber, J.T.2    Kaspar, B.K.3    Schaffer, D.V.4
  • 31
    • 73249136916 scopus 로고    scopus 로고
    • Identification of the murine AAVrh32.33 capsid-specific CD8+ T cell epitopes
    • Mays L.E., Wilson J.M. Identification of the murine AAVrh32.33 capsid-specific CD8+ T cell epitopes. J. Gene Med. 2009, 11:1095-1102.
    • (2009) J. Gene Med. , vol.11 , pp. 1095-1102
    • Mays, L.E.1    Wilson, J.M.2
  • 32
    • 70350101102 scopus 로고    scopus 로고
    • Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins
    • Mays L.E., Vandenberghe L.H., Xiao R., Bell P., Nam H.J., Agbandje-McKenna M., Wilson J.M. Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins. J. Immunol. 2009, 182:6051-6060.
    • (2009) J. Immunol. , vol.182 , pp. 6051-6060
    • Mays, L.E.1    Vandenberghe, L.H.2    Xiao, R.3    Bell, P.4    Nam, H.J.5    Agbandje-McKenna, M.6    Wilson, J.M.7
  • 33
    • 84883273969 scopus 로고    scopus 로고
    • Mapping the structural determinants responsible for enhanced T cell activation to the immunogenic adeno-associated virus capsid from isolate rhesus 32.33
    • Mays L.E., Wang L., Tenney R., Bell P., Nam H.J., Lin J., Gurda B., Van Vliet K., Mikals K., Agbandje-McKenna M., Wilson J.M. Mapping the structural determinants responsible for enhanced T cell activation to the immunogenic adeno-associated virus capsid from isolate rhesus 32.33. J. Virol. 2013, 87:9473-9485.
    • (2013) J. Virol. , vol.87 , pp. 9473-9485
    • Mays, L.E.1    Wang, L.2    Tenney, R.3    Bell, P.4    Nam, H.J.5    Lin, J.6    Gurda, B.7    Van Vliet, K.8    Mikals, K.9    Agbandje-McKenna, M.10    Wilson, J.M.11
  • 34
    • 84862329652 scopus 로고    scopus 로고
    • Structure of adeno-associated virus-2 in complex with neutralizing monoclonal antibody A20
    • McCraw D.M., O'Donnell J.K., Taylor K.A., Stagg S.M., Chapman M.S. Structure of adeno-associated virus-2 in complex with neutralizing monoclonal antibody A20. Virology 2012, 431:40-49.
    • (2012) Virology , vol.431 , pp. 40-49
    • McCraw, D.M.1    O'Donnell, J.K.2    Taylor, K.A.3    Stagg, S.M.4    Chapman, M.S.5
  • 36
    • 79954622209 scopus 로고    scopus 로고
    • Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
    • Mingozzi F., High K.A. Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges. Nat. Rev. Genet. 2011, 12:341-355.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 341-355
    • Mingozzi, F.1    High, K.A.2
  • 37
    • 79959932534 scopus 로고    scopus 로고
    • Immune responses to AAV in clinical trials
    • Mingozzi F., High K.A. Immune responses to AAV in clinical trials. Curr. Gene Ther. 2011, 11:321-330.
    • (2011) Curr. Gene Ther. , vol.11 , pp. 321-330
    • Mingozzi, F.1    High, K.A.2
  • 38
    • 0033920298 scopus 로고    scopus 로고
    • Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure
    • Moskalenko M., Chen L., van Roey M., Donahue B.A., Snyder R.O., McArthur J.G., Patel S.D. Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure. J. Virol. 2000, 74:1761-1766.
    • (2000) J. Virol. , vol.74 , pp. 1761-1766
    • Moskalenko, M.1    Chen, L.2    van Roey, M.3    Donahue, B.A.4    Snyder, R.O.5    McArthur, J.G.6    Patel, S.D.7
  • 40
    • 80655142508 scopus 로고    scopus 로고
    • Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking
    • Nam H.J., Gurda B.L., McKenna R., Potter M., Byrne B., Salganik M., Muzyczka N., Agbandje-McKenna M. Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J. Virol. 2011, 85:11791-11799.
    • (2011) J. Virol. , vol.85 , pp. 11791-11799
    • Nam, H.J.1    Gurda, B.L.2    McKenna, R.3    Potter, M.4    Byrne, B.5    Salganik, M.6    Muzyczka, N.7    Agbandje-McKenna, M.8
  • 42
    • 0035788101 scopus 로고    scopus 로고
    • Implementation of molecular replacement in AMoRe
    • Navaza J. Implementation of molecular replacement in AMoRe. Acta Crystallogr. D 2001, 57:1367-1372.
    • (2001) Acta Crystallogr. D , vol.57 , pp. 1367-1372
    • Navaza, J.1
  • 44
    • 60949103263 scopus 로고    scopus 로고
    • Adeno-associated virus-2 and its primary cellular receptor - Cryo-EM structure of a heparin complex
    • O'Donnell J., Taylor K.A., Chapman M.S. Adeno-associated virus-2 and its primary cellular receptor - Cryo-EM structure of a heparin complex. Virology 2009, 385:434-443.
    • (2009) Virology , vol.385 , pp. 434-443
    • O'Donnell, J.1    Taylor, K.A.2    Chapman, M.S.3
  • 47
    • 32844470411 scopus 로고    scopus 로고
    • Combinatorial engineering of a gene therapy vector: directed evolution of adeno-associated virus
    • Perabo L., Endell J., King S., Lux K., Goldnau D., Hallek M., Buning H. Combinatorial engineering of a gene therapy vector: directed evolution of adeno-associated virus. J. Gene Med. 2006, 8:155-162.
    • (2006) J. Gene Med. , vol.8 , pp. 155-162
    • Perabo, L.1    Endell, J.2    King, S.3    Lux, K.4    Goldnau, D.5    Hallek, M.6    Buning, H.7
  • 50
    • 84866169735 scopus 로고    scopus 로고
    • The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing
    • Raupp C., Naumer M., Muller O.J., Gurda B.L., Agbandje-McKenna M., Kleinschmidt J.A. The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing. J. Virol. 2012, 86:9396-9408.
    • (2012) J. Virol. , vol.86 , pp. 9396-9408
    • Raupp, C.1    Naumer, M.2    Muller, O.J.3    Gurda, B.L.4    Agbandje-McKenna, M.5    Kleinschmidt, J.A.6
  • 51
    • 0015156647 scopus 로고
    • Structural proteins of adenovirus-associated viruses
    • Rose J.A., Maizel J.V., Inman J.K., Shatkin A.J. Structural proteins of adenovirus-associated viruses. J. Virol. 1971, 8:766-770.
    • (1971) J. Virol. , vol.8 , pp. 766-770
    • Rose, J.A.1    Maizel, J.V.2    Inman, J.K.3    Shatkin, A.J.4
  • 52
    • 0042622380 scopus 로고    scopus 로고
    • SWISS-MODEL: an automated protein homology-modeling server
    • Schwede T., Kopp J., Guex N., Peitsch M.C. SWISS-MODEL: an automated protein homology-modeling server. Nucleic Acids Res. 2003, 31:3381-3385.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3381-3385
    • Schwede, T.1    Kopp, J.2    Guex, N.3    Peitsch, M.C.4
  • 53
    • 33750712806 scopus 로고    scopus 로고
    • Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus
    • Sonntag F., Bleker S., Leuchs B., Fischer R., Kleinschmidt J.A. Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus. J. Virol. 2006, 80:11040-11054.
    • (2006) J. Virol. , vol.80 , pp. 11040-11054
    • Sonntag, F.1    Bleker, S.2    Leuchs, B.3    Fischer, R.4    Kleinschmidt, J.A.5
  • 54
    • 0031058884 scopus 로고    scopus 로고
    • Rotation function calculations with GLRF program
    • Tong L., Rossmann M.G. Rotation function calculations with GLRF program. Methods Enzymol. 1997, 276:594-611.
    • (1997) Methods Enzymol. , vol.276 , pp. 594-611
    • Tong, L.1    Rossmann, M.G.2
  • 57
    • 17044394814 scopus 로고    scopus 로고
    • Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy
    • Wang L., Calcedo R., Nichols T.C., Bellinger D.A., Dillow A., Verma I.M., Wilson J.M. Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy. Blood 2005, 105:3079-3086.
    • (2005) Blood , vol.105 , pp. 3079-3086
    • Wang, L.1    Calcedo, R.2    Nichols, T.C.3    Bellinger, D.A.4    Dillow, A.5    Verma, I.M.6    Wilson, J.M.7
  • 58
    • 0033808531 scopus 로고    scopus 로고
    • Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection
    • Wobus C.E., Hugle-Dorr B., Girod A., Petersen G., Hallek M., Kleinschmidt J.A. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 2000, 74:9281-9293.
    • (2000) J. Virol. , vol.74 , pp. 9281-9293
    • Wobus, C.E.1    Hugle-Dorr, B.2    Girod, A.3    Petersen, G.4    Hallek, M.5    Kleinschmidt, J.A.6
  • 59
    • 34248172479 scopus 로고    scopus 로고
    • Interpretation of electron density with stereographic roadmap projections
    • Xiao C., Rossmann M.G., M.G. Interpretation of electron density with stereographic roadmap projections. J. Struct. Biol. 2007, 158:182-187.
    • (2007) J. Struct. Biol. , vol.158 , pp. 182-187
    • Xiao, C.1    Rossmann, M.G.2
  • 61
    • 80053386167 scopus 로고    scopus 로고
    • Structure-function analysis of receptor-binding in adeno-associated virus serotype 6 (AAV-6)
    • Xie Q., Lerch T.F., Meyer N.L., Chapman M.S. Structure-function analysis of receptor-binding in adeno-associated virus serotype 6 (AAV-6). Virology 2011, 420:10-19.
    • (2011) Virology , vol.420 , pp. 10-19
    • Xie, Q.1    Lerch, T.F.2    Meyer, N.L.3    Chapman, M.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.