-
1
-
-
37849012348
-
Alpha-Synuclein gene duplication is present in sporadic Parkinson disease
-
Ahn T.B., Kim S.Y., Kim J.Y., Park S.S., Lee D.S., Min H.J., Kim Y.K., Kim S.E., Kim J.M., Kim H.J., Cho J., Jeon B.S. alpha-Synuclein gene duplication is present in sporadic Parkinson disease. Neurology 2008, 70:43-49.
-
(2008)
Neurology
, vol.70
, pp. 43-49
-
-
Ahn, T.B.1
Kim, S.Y.2
Kim, J.Y.3
Park, S.S.4
Lee, D.S.5
Min, H.J.6
Kim, Y.K.7
Kim, S.E.8
Kim, J.M.9
Kim, H.J.10
Cho, J.11
Jeon, B.S.12
-
2
-
-
46149119425
-
Differential expression of alpha-synuclein, parkin, and synphilin-1 isoforms in Lewy body disease
-
Beyer K., Domingo-Sabat M., Humbert J., Carrato C., Ferrer I., Ariza A. Differential expression of alpha-synuclein, parkin, and synphilin-1 isoforms in Lewy body disease. Neurogenetics 2008, 9:163-172.
-
(2008)
Neurogenetics
, vol.9
, pp. 163-172
-
-
Beyer, K.1
Domingo-Sabat, M.2
Humbert, J.3
Carrato, C.4
Ferrer, I.5
Ariza, A.6
-
3
-
-
38649119157
-
Identification and characterization of a new alpha-synuclein isoform and its role in Lewy body diseases
-
Beyer K., Domingo-Sabat M., Lao J.I., Carrato C., Ferrer I., Ariza A. Identification and characterization of a new alpha-synuclein isoform and its role in Lewy body diseases. Neurogenetics 2008, 9:15-23.
-
(2008)
Neurogenetics
, vol.9
, pp. 15-23
-
-
Beyer, K.1
Domingo-Sabat, M.2
Lao, J.I.3
Carrato, C.4
Ferrer, I.5
Ariza, A.6
-
4
-
-
33747778534
-
Low alpha-synuclein 126 mRNA levels in dementia with Lewy bodies and Alzheimer disease
-
Beyer K., Humbert J., Ferrer A., Lao J.I., Carrato C., Lopez D., Ferrer I., Ariza A. Low alpha-synuclein 126 mRNA levels in dementia with Lewy bodies and Alzheimer disease. Neuroreport 2006, 17:1327-1330.
-
(2006)
Neuroreport
, vol.17
, pp. 1327-1330
-
-
Beyer, K.1
Humbert, J.2
Ferrer, A.3
Lao, J.I.4
Carrato, C.5
Lopez, D.6
Ferrer, I.7
Ariza, A.8
-
5
-
-
9444233904
-
Differential expression of alpha-synuclein isoforms in dementia with Lewy bodies
-
Beyer K., Lao J.I., Carrato C., Mate J.L., Lopez D., Ferrer I., Ariza A. Differential expression of alpha-synuclein isoforms in dementia with Lewy bodies. Neuropathol. Appl. Neurobiol. 2004, 30:601-607.
-
(2004)
Neuropathol. Appl. Neurobiol.
, vol.30
, pp. 601-607
-
-
Beyer, K.1
Lao, J.I.2
Carrato, C.3
Mate, J.L.4
Lopez, D.5
Ferrer, I.6
Ariza, A.7
-
6
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin M.C., Kachergus J., Roumier C., Mouroux V., Douay X., Lincoln S., Levecque C., Larvor L., Andrieux J., Hulihan M., Waucquier N., Defebvre L., Amouyel P., Farrer M., Destee A. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 2004, 364:1167-1169.
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destee, A.15
-
7
-
-
34548172773
-
Different species of alpha-synuclein oligomers induce calcium influx and seeding
-
Danzer K.M., Haasen D., Karow A.R., Moussaud S., Habeck M., Giese A., Kretzschmar H., Hengerer B., Kostka M. Different species of alpha-synuclein oligomers induce calcium influx and seeding. J.Neurosci. 2007, 27:9220-9232.
-
(2007)
J.Neurosci.
, vol.27
, pp. 9220-9232
-
-
Danzer, K.M.1
Haasen, D.2
Karow, A.R.3
Moussaud, S.4
Habeck, M.5
Giese, A.6
Kretzschmar, H.7
Hengerer, B.8
Kostka, M.9
-
8
-
-
0033678217
-
Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies
-
Duda J.E., Giasson B.I., Chen Q., Gur T.L., Hurtig H.I., Stern M.B., Gollomp S.M., Ischiropoulos H., Lee V.M., Trojanowski J.Q. Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies. Am. J. Pathol. 2000, 157:1439-1445.
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1439-1445
-
-
Duda, J.E.1
Giasson, B.I.2
Chen, Q.3
Gur, T.L.4
Hurtig, H.I.5
Stern, M.B.6
Gollomp, S.M.7
Ischiropoulos, H.8
Lee, V.M.9
Trojanowski, J.Q.10
-
9
-
-
0036174010
-
Alpha-Synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara H., Hasegawa M., Dohmae N., Kawashima A., Masliah E., Goldberg M.S., Shen J., Takio K., Iwatsubo T. alpha-Synuclein is phosphorylated in synucleinopathy lesions. Nat. Cell Biol. 2002, 4:160-164.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
Shen, J.7
Takio, K.8
Iwatsubo, T.9
-
10
-
-
2942555022
-
Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling
-
Jao C.C., Der-Sarkissian A., Chen J., Langen R. Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling. Proc. Natl. Acad. Sci. U.S.A 2004, 101:8331-8336.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 8331-8336
-
-
Jao, C.C.1
Der-Sarkissian, A.2
Chen, J.3
Langen, R.4
-
11
-
-
0036415838
-
Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils
-
Lashuel H.A., Petre B.M., Wall J., Simon M., Nowak R.J., Walz T., Lansbury P.T. Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils. J.Mol. Biol. 2002, 322:1089-1102.
-
(2002)
J.Mol. Biol.
, vol.322
, pp. 1089-1102
-
-
Lashuel, H.A.1
Petre, B.M.2
Wall, J.3
Simon, M.4
Nowak, R.J.5
Walz, T.6
Lansbury, P.T.7
-
12
-
-
0037016741
-
Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form
-
Lee H.J., Choi C., Lee S.J. Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form. J.Biol. Chem. 2002, 277:671-678.
-
(2002)
J.Biol. Chem.
, vol.277
, pp. 671-678
-
-
Lee, H.J.1
Choi, C.2
Lee, S.J.3
-
13
-
-
0038116620
-
Role of alpha-synuclein carboxy-terminus on fibril formation invitro
-
Murray I.V., Giasson B.I., Quinn S.M., Koppaka V., Axelsen P.H., Ischiropoulos H., Trojanowski J.Q., Lee V.M. Role of alpha-synuclein carboxy-terminus on fibril formation invitro. Biochemistry 2003, 42:8530-8540.
-
(2003)
Biochemistry
, vol.42
, pp. 8530-8540
-
-
Murray, I.V.1
Giasson, B.I.2
Quinn, S.M.3
Koppaka, V.4
Axelsen, P.H.5
Ischiropoulos, H.6
Trojanowski, J.Q.7
Lee, V.M.8
-
14
-
-
48249107510
-
Accumulation and clearance of alpha-synuclein aggregates demonstrated by time-lapse imaging
-
Opazo F., Krenz A., Heermann S., Schulz J.B., Falkenburger B.H. Accumulation and clearance of alpha-synuclein aggregates demonstrated by time-lapse imaging. J.Neurochem. 2008, 106:529-540.
-
(2008)
J.Neurochem.
, vol.106
, pp. 529-540
-
-
Opazo, F.1
Krenz, A.2
Heermann, S.3
Schulz, J.B.4
Falkenburger, B.H.5
-
15
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W.G., Lazzarini A.M., Duvoisin R.C., Di Iorio G., Golbe L.I., Nussbaum R.L. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997, 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
16
-
-
70549088602
-
Genome-wide association studyreveals genetic risk underlying Parkinson's disease
-
Simon-Sanchez J., Schulte C., Bras J.M., Sharma M., Gibbs J.R., Berg D., Paisan-Ruiz C., Lichtner P., Scholz S.W., Hernandez D.G., Kruger R., Federoff M., Klein C., Goate A., Perlmutter J., Bonin M., Nalls M.A., Illig T., Gieger C., Houlden H., Steffens M., Okun M.S., Racette B.A., Cookson M.R., Foote K.D., Fernandez H.H., Traynor B.J., Schreiber S., Arepalli S., Zonozi R., Gwinn K., van der Brug M., Lopez G., Chanock S.J., Schatzkin A., Park Y., Hollenbeck A., Gao J., Huang X., Wood N.W., Lorenz D., Deuschl G., Chen H., Riess O., Hardy J.A., Singleton A.B., Gasser T. Genome-wide association studyreveals genetic risk underlying Parkinson's disease. Nat. Genet. 2009, 41:1308-1312.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
Sharma, M.4
Gibbs, J.R.5
Berg, D.6
Paisan-Ruiz, C.7
Lichtner, P.8
Scholz, S.W.9
Hernandez, D.G.10
Kruger, R.11
Federoff, M.12
Klein, C.13
Goate, A.14
Perlmutter, J.15
Bonin, M.16
Nalls, M.A.17
Illig, T.18
Gieger, C.19
Houlden, H.20
Steffens, M.21
Okun, M.S.22
Racette, B.A.23
Cookson, M.R.24
Foote, K.D.25
Fernandez, H.H.26
Traynor, B.J.27
Schreiber, S.28
Arepalli, S.29
Zonozi, R.30
Gwinn, K.31
van der Brug, M.32
Lopez, G.33
Chanock, S.J.34
Schatzkin, A.35
Park, Y.36
Hollenbeck, A.37
Gao, J.38
Huang, X.39
Wood, N.W.40
Lorenz, D.41
Deuschl, G.42
Chen, H.43
Riess, O.44
Hardy, J.A.45
Singleton, A.B.46
Gasser, T.47
more..
-
17
-
-
0242300619
-
Alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton A.B., Farrer M., Johnson J., Singleton A., Hague S., Kachergus J., Hulihan M., Peuralinna T., Dutra A., Nussbaum R., Lincoln S., Crawley A., Hanson M., Maraganore D., Adler C., Cookson M.R., Muenter M., Baptista M., Miller D., Blancato J., Hardy J., Gwinn-Hardy K. alpha-Synuclein locus triplication causes Parkinson's disease. Science 2003, 302:841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
18
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini M.G., Schmidt M.L., Lee V.M., Trojanowski J.Q., Jakes R., Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997, 388:839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
19
-
-
0344944630
-
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
-
Stefani M., Dobson C.M. Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J.Mol. Med. 2003, 81:678-699.
-
(2003)
J.Mol. Med.
, vol.81
, pp. 678-699
-
-
Stefani, M.1
Dobson, C.M.2
-
20
-
-
33947210032
-
Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein
-
Tsigelny I.F., Bar-On P., Sharikov Y., Crews L., Hashimoto M., Miller M.A., Keller S.H., Platoshyn O., Yuan J.X., Masliah E. Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein. FEBS J. 2007, 274:1862-1877.
-
(2007)
FEBS J.
, vol.274
, pp. 1862-1877
-
-
Tsigelny, I.F.1
Bar-On, P.2
Sharikov, Y.3
Crews, L.4
Hashimoto, M.5
Miller, M.A.6
Keller, S.H.7
Platoshyn, O.8
Yuan, J.X.9
Masliah, E.10
-
21
-
-
15744362063
-
Structure and dynamics of micelle-bound human alpha-synuclein
-
Ulmer T.S., Bax A., Cole N.B., Nussbaum R.L. Structure and dynamics of micelle-bound human alpha-synuclein. J.Biol. Chem. 2005, 280:9595-9603.
-
(2005)
J.Biol. Chem.
, vol.280
, pp. 9595-9603
-
-
Ulmer, T.S.1
Bax, A.2
Cole, N.B.3
Nussbaum, R.L.4
-
22
-
-
34548620297
-
Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation
-
Uversky V.N. Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation. J.Neurochem. 2007, 103:17-37.
-
(2007)
J.Neurochem.
, vol.103
, pp. 17-37
-
-
Uversky, V.N.1
|