Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells

Radiation Oncology

Volumn 9, Issue 1, 2014, Pages

  Wirsdörfer, Florian ^a   Cappuccini, Federica ^a   Niazman, Muska ^a   de Leve, Simone ^a   Westendorf, Astrid M ^a   Lüdemann, Lutz ^a   Stuschke, Martin ^a   Jendrossek, Verena ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Fibrosis; Pneumonitis; Regulatory T cells; T lymphocytes; Thorax irradiation

Indexed keywords

5' NUCLEOTIDASE; CD103 ANTIGEN; COBALT 60; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 17; MEMBRANE PROTEIN; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD4+ TRANSCRIPTION FACTOR FOXP3+ REGULATORY T LYMPHOCYTE; CERVICAL LYMPH NODE; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOCOMPETENT CELL; IRRADIATION; LUNG FIBROSIS; LUNG LAVAGE; LUNG PARENCHYMA; LYMPHOID TISSUE; MOUSE; NONHUMAN; PHENOTYPE; PNEUMONIA; PROTEIN EXPRESSION; RADIATION DOSE; REGULATORY T LYMPHOCYTE; SINGLE DRUG DOSE; SPLEEN; TH17 CELL; WILD TYPE; ANIMAL; C57BL MOUSE; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; LUNG; LYMPH NODE; METABOLISM; RADIATION RESPONSE; THORAX;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; FORKHEAD TRANSCRIPTION FACTORS; IMMUNOSUPPRESSION; LUNG; LYMPH NODES; MICE; MICE, INBRED C57BL; SPLEEN; T-LYMPHOCYTES, REGULATORY; THORAX;

EID: 84899926177     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-9-98     Document Type: Article

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