SCOPUS 정보 검색 플랫폼

Volumn 12, Issue 21, 2014, Pages 3446-3458

Design, synthesis, and biological evaluation of novel trifluoromethyl indoles as potent HIV-1 NNRTIs with an improved drug resistance profile

(9) Jiang, Hai Xia a Zhuang, Dao Min b Huang, Ying a Cao, Xing Xin a Yao, Jian Hua a Li, Jing Yun b Wang, Jian Yong c Zhang, Chen a Jiang, Biao a,c

a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY (China)

b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY (China)

c SHANGHAI ADVANCED RESEARCH INSTITUTE (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMISTRY; POSITIVE IONS;

ACUTE TOXICITY; ANTI-HIV-1 ACTIVITY; BIOLOGICAL EVALUATION; DOCKING STUDIES; DRUG RESISTANCE; INDOLE DERIVATIVES; NANOMOLAR LEVELS; TRIFLUOROMETHYL;

BINDING ENERGY;

3-HYDROXYBUTANAL; ALDEHYDE; BENZOXAZINE DERIVATIVE; CARCINOGEN; EFAVIRENZ; INDOLE DERIVATIVE; LIGAND; MUTAGENIC AGENT; MUTANT PROTEIN; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ANTIVIRAL RESISTANCE; CATALYSIS; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; SYNTHESIS;

ALDEHYDES; BENZOXAZINES; CARCINOGENS; CATALYSIS; CELL LINE; DRUG DESIGN; DRUG RESISTANCE, VIRAL; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; INDOLES; LIGANDS; MODELS, MOLECULAR; MUTAGENS; MUTANT PROTEINS; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 84899915262 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c3ob42186d Document Type: Article

Times cited : (40)

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