Inhibition of follicle-stimulating hormone-induced preovulatory follicles in rats treated with a nonsteroidal negative allosteric modulator of follicle-stimulating hormone receptor

Biology of Reproduction

Volumn 90, Issue 1, 2014, Pages

  Dias, James A ^a,b   Campo, Brice ^c   Weaver, Barbara A ^a   Watts, Julie ^a   Kluetzman, Kerri ^a,b   Thomas, Richard M ^a   Bonnet, Béatrice ^c   Mutel, Vincent ^d   Poli, Sonia M ^c  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c ADDEX PHARMACEUTICALS   (Switzerland)

^d Inflamalps SA   (Switzerland)

Author keywords

Contraception; Follicle stimulating hormone (FSH FSH receptor); Follicular maturation; Negative allosteric modulator; Small molecule

Indexed keywords

ADX 68692; ADX 68693; CONTRACEPTIVE AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ESTRADIOL; FOLLITROPIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; IODINE 125; ISOBUTYLMETHYLXANTHINE; PROGESTERONE; RECOMBINANT FOLLITROPIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; CONTRACEPTION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; ENDOMETRIOSIS; ESTRUS CYCLE; FEMALE; FERTILITY; GRANULOSA CELL; HIGH THROUGHPUT SCREENING; HORMONE ACTION; IMPLANTATION; IN VITRO STUDY; NIDATION; NONHUMAN; OOCYTE; OOCYTE MATURATION; OVARY FOLLICLE; OVARY FOLLICLE DEVELOPMENT; OVULATION; PRIMARY CELL CULTURE; PRIORITY JOURNAL; RADIOIODINATION; RAT;

CONTRACEPTION; FOLLICLE-STIMULATING HORMONE (FSH/FSH RECEPTOR); FOLLICULAR MATURATION; NEGATIVE ALLOSTERIC MODULATOR; SMALL MOLECULE;

ALLOSTERIC REGULATION; ANIMALS; BENZAMIDES; CELLS, CULTURED; FEMALE; FOLLICLE STIMULATING HORMONE; FOLLICULAR PHASE; HORMONE ANTAGONISTS; MALE; OVARIAN FOLLICLE; OVULATION INDUCTION; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, FSH;

EID: 84899902006     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.109397     Document Type: Article

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