Antagonistic functions of LMNA isoforms in energy expenditure and lifespan

EMBO Reports

Volumn 15, Issue 5, 2014, Pages 529-539

  Lopez Mejia, Isabel C ^a,b   De Toledo, Marion ^a   Chavey, Carine ^a   Lapasset, Laure ^a   Cavelier, Patricia ^a   Lopez Herrera, Celia ^a   Chebli, Karim ^a   Fort, Philippe ^c   Beranger, Guillaume ^d   Fajas, Lluis ^b   Amri, Ez Z ^d   Casas, François ^e   Tazi, Jamal ^a  

^a INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c Centre National de la Recherche Scientifique   (France)

^d INSERM   (France)

^e University of Montpellier   (France)

Author keywords

aging; energy expenditure; LMNA protein isoforms; mitochondria biogenesis; RNA processing

Indexed keywords

ISOPROTEIN; LAMIN A; LAMIN C; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SECRETED FRIZZLED RELATED PROTEIN 5; TRANSCRIPTOME; LMNA PROTEIN, MOUSE; NUCLEAR PROTEIN; PPARGC1A PROTEIN, MOUSE; PRELAMIN A; PROTEIN PRECURSOR; SFRP5 PROTEIN, MOUSE; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR;

ADIPOSE TISSUE; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BREATHING; CONTROLLED STUDY; ENERGY EXPENDITURE; ENERGY METABOLISM; HUMAN; LIFESPAN; METABOLISM; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; WEIGHT GAIN; ADIPOCYTE; ALTERNATIVE RNA SPLICING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; GENE EXPRESSION; GENETICS; LONGEVITY; PHYSIOLOGY; PROGERIA; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADIPOCYTES; ADIPOSE TISSUE; AGING; ALTERNATIVE SPLICING; ANIMALS; CELLS, CULTURED; ENERGY METABOLISM; GENE EXPRESSION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LAMIN TYPE A; LONGEVITY; MICE; MICE, TRANSGENIC; MITOCHONDRIA; NUCLEAR PROTEINS; PROGERIA; PROTEIN ISOFORMS; PROTEIN PRECURSORS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84899891410     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1002/embr.201338126     Document Type: Article

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