메뉴 건너뛰기




Volumn 8, Issue 1, 2014, Pages 12-17

Impact of CYP3A5 gene polymorphism on efficacy of simvastatin

Author keywords

CYP3A5 gene polymorphism; Low density lipoprotein cholesterol; Simvastatin

Indexed keywords

CYTOCHROME P450 3A5; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SIMVASTATIN; TRIACYLGLYCEROL; GLUCOSE; LIPID;

EID: 84899879703     PISSN: None     EISSN: 18741924     Source Type: Journal    
DOI: 10.2174/1874192401408010012     Document Type: Article
Times cited : (8)

References (23)
  • 2
    • 70450207712 scopus 로고    scopus 로고
    • Cholesterol ester transfer protein (CETP), postprandial lipemia and hypolipidemic drugs
    • Kolovou GD, Anagnostopoulou KK, Kostakou PM, Mikhailidis DP. Cholesterol ester transfer protein (CETP), postprandial lipemia and hypolipidemic drugs. Curr Med Chem 2009; 16: 4345-60.
    • (2009) Curr Med Chem , vol.16 , pp. 4345-4360
    • Kolovou, G.D.1    Anagnostopoulou, K.K.2    Kostakou, P.M.3    Mikhailidis, D.P.4
  • 3
    • 35748960257 scopus 로고    scopus 로고
    • Pharmacogenetic study of cholesteryl ester transfer protein gene and simvastatin treatment in hypercholesterolaemic subjects
    • Anagnostopoulou KK, Kolovou GD, Kostakou PM, et al. Pharmacogenetic study of cholesteryl ester transfer protein gene and simvastatin treatment in hypercholesterolaemic subjects. Expert Opin Pharmacother 2007; 8: 2459-63.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 2459-2463
    • Anagnostopoulou, K.K.1    Kolovou, G.D.2    Kostakou, P.M.3
  • 4
    • 0038336614 scopus 로고    scopus 로고
    • The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6
    • Prueksaritanont T, Ma B, Yu N. The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6. Br J Clin Pharmacol 2003; 56: 120-4.
    • (2003) Br J Clin Pharmacol , vol.56 , pp. 120-124
    • Prueksaritanont, T.1    Ma, B.2    Yu, N.3
  • 5
    • 77957557404 scopus 로고    scopus 로고
    • Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids
    • Dvorak Z, Pavek P. Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids. Drug Metab Rev 2010; 42: 621-35.
    • (2010) Drug Metab Rev , vol.42 , pp. 621-635
    • Dvorak, Z.1    Pavek, P.2
  • 6
    • 84868571010 scopus 로고    scopus 로고
    • Induction of cytochrome P450 enzymes: A view on human in vivo findings
    • Hukkanen J. Induction of cytochrome P450 enzymes: a view on human in vivo findings. Expert Rev Clin Pharmacol 2012; 5: 569-85
    • (2012) Expert Rev Clin Pharmacol , vol.5 , pp. 569-585
    • Hukkanen, J.1
  • 7
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • Kuehl P, Zhang J, Lin Y, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 2001; 27: 383-91.
    • (2001) Nat Genet , vol.27 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3
  • 8
  • 9
    • 34447269513 scopus 로고    scopus 로고
    • Genetic polymorphisms of drug-metabolizing enzymes CYP2D6, CYP2C9, CYP2C19 and CYP3A5 in the Greek population
    • Arvanitidis K, Ragia G, Iordanidou M, et al. Genetic polymorphisms of drug-metabolizing enzymes CYP2D6, CYP2C9, CYP2C19 and CYP3A5 in the Greek population. Fundam Clin Pharmacol 2007; 21: 419-26.
    • (2007) Fundam Clin Pharmacol , vol.21 , pp. 419-426
    • Arvanitidis, K.1    Ragia, G.2    Iordanidou, M.3
  • 10
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • National Heart, Lung, and Blood Institute; American College of Cardiology Foundation; American Heart Association
    • Grundy SM, Cleeman JI, Merz CN, et al; National Heart, Lung, and Blood Institute; American College of Cardiology Foundation; American Heart Association. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 2004; 110: 227-39.
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.3
  • 11
    • 79956099377 scopus 로고    scopus 로고
    • Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: Systematic review and metaanalysis
    • Mikhailidis DP, Lawson RW, McCormick AL, et al. Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and metaanalysis. Curr Med Res Opin 2011; 27: 1191-210.
    • (2011) Curr Med Res Opin , vol.27 , pp. 1191-1210
    • Mikhailidis, D.P.1    Lawson, R.W.2    McCormick, A.L.3
  • 12
    • 70549109148 scopus 로고    scopus 로고
    • Frequency of common CYP3A5 gene variants in healthy Polish newborn infants
    • Kuehl P, Zhang J, Lin Y, et al. Frequency of common CYP3A5 gene variants in healthy Polish newborn infants. Pharmacol Rep 2009; 61: 947-51.
    • (2009) Pharmacol Rep , vol.61 , pp. 947-951
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3
  • 13
    • 54049115013 scopus 로고    scopus 로고
    • CYP3A53A allele is associated with reduced lowering-lipid response to atorvastatin in individuals with hypercholesterolemia
    • Willrich MA, Hirata MH, Genvigir FD, et al. CYP3A53A allele is associated with reduced lowering-lipid response to atorvastatin in individuals with hypercholesterolemia. Clin Chim Acta 2008; 398: 15-20.
    • (2008) Clin Chim Acta , vol.398 , pp. 15-20
    • Willrich, M.A.1    Hirata, M.H.2    Genvigir, F.D.3
  • 14
    • 84355166408 scopus 로고    scopus 로고
    • Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia
    • Rosales A, Alvear M, Cuevas A, Saavedra N, Zambrano T, Salazar LA. Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia. Clin Chim Acta 2012; 413: 495-501.
    • (2012) Clin Chim Acta , vol.413 , pp. 495-501
    • Rosales, A.1    Alvear, M.2    Cuevas, A.3    Saavedra, N.4    Zambrano, T.5    Salazar, L.A.6
  • 15
    • 79551697201 scopus 로고    scopus 로고
    • CYP3AP1*3 allele is associated with lipid-lowering efficacy of simvastatin and atorvastatin in Chinese women
    • Li YP, Zhang LR, Jia M, Hu XJ. CYP3AP1*3 allele is associated with lipid-lowering efficacy of simvastatin and atorvastatin in Chinese women. J Clin Pharmacol 2011; 51: 181-8.
    • (2011) J Clin Pharmacol , vol.51 , pp. 181-188
    • Li, Y.P.1    Zhang, L.R.2    Jia, M.3    Hu, X.J.4
  • 16
    • 4143049054 scopus 로고    scopus 로고
    • Lipid-lowering response to statins is affected by CYP3A5 polymorphism
    • Kivistö KT, Niemi M, Schaeffeler E, et al. Lipid-lowering response to statins is affected by CYP3A5 polymorphism. Pharmacogenetics 2004; 14: 523-5.
    • (2004) Pharmacogenetics , vol.14 , pp. 523-525
    • Kivistö, K.T.1    Niemi, M.2    Schaeffeler, E.3
  • 17
    • 80053339932 scopus 로고    scopus 로고
    • Effect of cytochrome P450 3A5 genotype on atorvastatin pharmacokinetics and its interaction with clarithromycin
    • Shin J, Pauly DF, Pacanowski MA, Langaee T, Frye RF, Johnson JA. Effect of cytochrome P450 3A5 genotype on atorvastatin pharmacokinetics and its interaction with clarithromycin. Pharmacotherapy 2011; 31: 942-50.
    • (2011) Pharmacotherapy , vol.31 , pp. 942-950
    • Shin, J.1    Pauly, D.F.2    Pacanowski, M.A.3    Langaee, T.4    Frye, R.F.5    Johnson, J.A.6
  • 18
    • 33845806096 scopus 로고    scopus 로고
    • Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects
    • Kim KA, Park PW, Lee OJ, Kang DK, Park JY. Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects. J Clin Pharmacol 2007; 47: 87-93.
    • (2007) J Clin Pharmacol , vol.47 , pp. 87-93
    • Kim, K.A.1    Park, P.W.2    Lee, O.J.3    Kang, D.K.4    Park, J.Y.5
  • 19
    • 79960633918 scopus 로고    scopus 로고
    • Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
    • Wang D, Guo Y, Wrighton SA, Cooke GE, Sadee W. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. Pharmacogenomics J 2011; 11: 274-86.
    • (2011) Pharmacogenomics J , vol.11 , pp. 274-286
    • Wang, D.1    Guo, Y.2    Wrighton, S.A.3    Cooke, G.E.4    Sadee, W.5
  • 20
    • 84857273073 scopus 로고    scopus 로고
    • Cytochrome P450 variations in different ethnic populations
    • McGraw J, Waller D. Cytochrome P450 variations in different ethnic populations. Expert Opin Drug Metab Toxicol 2012; 8: 371-82.
    • (2012) Expert Opin Drug Metab Toxicol , vol.8 , pp. 371-382
    • McGraw, J.1    Waller, D.2
  • 21
  • 22
    • 84875867323 scopus 로고    scopus 로고
    • Simvastatin pharmacokinetics in healthy Chinese subjects and its relations with CYP2C9, CYP3A5, ABCB1, ABCG2 and SLCO1B1 polymorphisms
    • Zhou Q, Ruan ZR, Jiang B, Yuan H, Zeng S. Simvastatin pharmacokinetics in healthy Chinese subjects and its relations with CYP2C9, CYP3A5, ABCB1, ABCG2 and SLCO1B1 polymorphisms. Pharmazie 2013; 68: 124-8.
    • (2013) Pharmazie , vol.68 , pp. 124-128
    • Zhou, Q.1    Ruan, Z.R.2    Jiang, B.3    Yuan, H.4    Zeng, S.5
  • 23
    • 84906791063 scopus 로고    scopus 로고
    • The pharmacogenomics of statins
    • Dec 21, doi: 10. 1016/j. phrs. 2013. 12. 002. [Epub ahead of print]
    • Gelissen IC, McLachlan AJ. The pharmacogenomics of statins. Pharmacol Res 2013 Dec 21. doi: 10. 1016/j. phrs. 2013. 12. 002. [Epub ahead of print]
    • (2013) Pharmacol Res
    • Gelissen, I.C.1    McLachlan, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.