메뉴 건너뛰기




Volumn 8, Issue 3, 2012, Pages 371-382

Cytochrome P450 variations in different ethnic populations

Author keywords

African American; CYP450; Drug; Ethnicity; Genotype; Phenotype; Polymorphism; Race; Xenobiotic

Indexed keywords

AFLATOXIN; AMFEBUTAMONE; CHLORZOXAZONE; CLOZAPINE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2C8; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DESIPRAMINE; DEXTROMETHORPHAN; DICLOFENAC; ISOPROTEIN; LEFLUNOMIDE; LOSARTAN; MELATONIN; MEPHENYTOIN; METOPROLOL; MIDAZOLAM; OLANZAPINE; OMEPRAZOLE; PACLITAXEL; RILUZOLE; SIMVASTATIN; TACROLIMUS; TAMOXIFEN; THEOPHYLLINE; TOLBUTAMIDE; WARFARIN;

EID: 84857273073     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1517/17425255.2012.657626     Document Type: Review
Times cited : (233)

References (88)
  • 4
    • 53349095856 scopus 로고    scopus 로고
    • Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa
    • Yaeger R, Avila-Bront A, Abdul K, et al. Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev 2008;17:1329-38
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 1329-38
    • Yaeger, R.1    Avila-Bront, A.2    Abdul, K.3
  • 5
    • 84857248363 scopus 로고    scopus 로고
    • American Society of Health-System Pharmacists; Bethesda, MD
    • Zdanowicz. Concepts in Pharmacogenomics. American Society of Health-System Pharmacists; Bethesda, MD; 2010
    • (2010) Concepts in Pharmacogenomics
    • Zdanowicz1
  • 6
    • 84857248351 scopus 로고    scopus 로고
    • August14 Cited 29 August 2010
    • Nelson D. The Cytochrome P450 Homepage. 2009.August14 2009.Available from: http://drnelson. uthsc.edu/human.P450.table.html [Cited 29 August 2010]
    • (2009) The Cytochrome P450 Homepage , vol.2009
    • Nelson, D.1
  • 7
    • 33745668685 scopus 로고    scopus 로고
    • Role of CYP pharmacogenetics and drug-drug interactions in the efficacy and safety of atypical and other antipsychotic agents
    • DOI 10.1211/jpp.58.7.0001
    • Murray M. Role of CYP pharmacogenetics and drug-drug interactions in the efficacy and safety of atypical and other antipsychotic agents. J Pharm Pharmacol 2006;58:871-85 (Pubitemid 43967103)
    • (2006) Journal of Pharmacy and Pharmacology , vol.58 , Issue.7 , pp. 871-885
    • Murray, M.1
  • 8
    • 75549086408 scopus 로고    scopus 로고
    • SuperCYP: A comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions
    • Preissner S, Kroll K, Dunkel M, et al. SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res 2009;38:D237-43
    • (2009) Nucleic Acids Res , vol.38
    • Preissner, S.1    Kroll, K.2    Dunkel, M.3
  • 9
    • 1642494659 scopus 로고    scopus 로고
    • "Cocktail" Approaches and Strategies in Drug Development: Valuable Tool or Flawed Science?
    • DOI 10.1177/0091270003261333
    • Zhou H, Tong Z, McLeod JF. "Cocktail" approaches and strategies in drug development: valuable tool or flawed science? J Clin Pharmacol 2004;44:120-34 (Pubitemid 38114310)
    • (2004) Journal of Clinical Pharmacology , vol.44 , Issue.2 , pp. 120-134
    • Zhou, H.1    Tong, Z.2    McLeod, J.F.3
  • 11
    • 44949222437 scopus 로고    scopus 로고
    • Variation in CYP1A2 activity and its clinical implications: Influence of environmental factors and genetic polymorphisms
    • DOI 10.2217/14622416.9.5.625
    • Gunes A, Dahl ML. Variation in CYP1A2 activity and its clinical implications: influence of environmental factors and genetic polymorphisms. Pharmacogenomics 2008;9:625-37 (Pubitemid 351803920)
    • (2008) Pharmacogenomics , vol.9 , Issue.5 , pp. 625-637
    • Gunes, A.1    Dahl, M.-L.2
  • 12
    • 70149110672 scopus 로고    scopus 로고
    • Polymorphism of human cytochrome P450 enzymes and its clinical impact
    • Zhou SF, Liu JP, Chowbay B. Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metab Rev 2009;41:89-295
    • (2009) Drug Metab Rev , vol.41 , pp. 89-295
    • Zhou, S.F.1    Liu, J.P.2    Chowbay, B.3
  • 13
    • 0042856457 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP1A2 in ethiopians affecting induction and expression: Characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1
    • DOI 10.1124/mol.64.3.659
    • Aklillu E, Carrillo JA, Makonnen E, et al. Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1. Mol Pharmacol 2003;64:659-69 (Pubitemid 37048569)
    • (2003) Molecular Pharmacology , vol.64 , Issue.3 , pp. 659-669
    • Aklillu, E.1    Carrillo, J.A.2    Makonnen, E.3    Hellman, K.4    Pitarque, M.5    Bertilsson, L.6    Ingelman-Sundberg, M.7
  • 14
    • 0036433001 scopus 로고    scopus 로고
    • Inducibility of CYP1A2 by omeprazole in vivo related to the genetic polymorphism of CYP1A2
    • Han XM, Ouyang DS, Chen XP, et al. Inducibility of CYP1A2 by omeprazole in vivo related to the genetic polymorphism of CYP1A2. Br J Clin Pharmacol 2002;54:540-3
    • (2002) Br J Clin Pharmacol , vol.54 , pp. 540-3
    • Han, X.M.1    Ouyang, D.S.2    Chen, X.P.3
  • 15
    • 0032908778 scopus 로고    scopus 로고
    • Functional significance of a CA polymorphism in intron I of the cytochrome P450 CYP1A2 gene tested with caffeine
    • DOI 10.1046/j.1365-2125.1999.00898.x
    • Sachse C, Brockmoller J, Bauer S, et al. Functional significance of a C- > A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol 1999;47:445-9 (Pubitemid 29161279)
    • (1999) British Journal of Clinical Pharmacology , vol.47 , Issue.4 , pp. 445-449
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 18
    • 78049268075 scopus 로고    scopus 로고
    • Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine
    • Gentile G, Borro M, Lala N, et al. Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine. J Headache Pain 2010;11:431-5
    • (2010) J Headache Pain , vol.11 , pp. 431-5
    • Gentile, G.1    Borro, M.2    Lala, N.3
  • 19
    • 75549088045 scopus 로고    scopus 로고
    • Pharmacogenetics and olanzapine treatment: CYP1A2 1F and serotonergic polymorphisms influence therapeutic outcome
    • Laika B, Leucht S, Heres S, et al. Pharmacogenetics and olanzapine treatment: CYP1A2 1F and serotonergic polymorphisms influence therapeutic outcome. Pharmacogenomics J 2010;10:20-9
    • (2010) Pharmacogenomics J , vol.10 , pp. 20-9
    • Laika, B.1    Leucht, S.2    Heres, S.3
  • 20
    • 50849104253 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients
    • Bohanec Grabar P, Rozman B, Tomsic M, et al. Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. Eur J Clin Pharmacol 2008;64:871-6
    • (2008) Eur J Clin Pharmacol , vol.64 , pp. 871-6
    • Bohanec Grabar, P.1    Rozman, B.2    Tomsic, M.3
  • 21
    • 72949119743 scopus 로고    scopus 로고
    • Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6
    • Mo SL, Liu YH, Duan W, et al. Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. Curr Drug Metab 2009;10:730-53
    • (2009) Curr Drug Metab , vol.10 , pp. 730-53
    • Mo, S.L.1    Liu, Y.H.2    Duan, W.3
  • 22
    • 33646205301 scopus 로고    scopus 로고
    • Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals
    • Garcia-Martin E, Martinez C, Ladero JM, et al. Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals. Mol Diagn Ther 2006;10:29-40
    • (2006) Mol Diagn Ther , vol.10 , pp. 29-40
    • Garcia-Martin, E.1    Martinez, C.2    Ladero, J.M.3
  • 24
    • 70649111382 scopus 로고    scopus 로고
    • CYP2C9 8 is prevalent among African- Americans: Implications for pharmacogenetic dosing
    • Scott SA, Jaremko M, Lubitz SA, et al. CYP2C9 8 is prevalent among African- Americans: implications for pharmacogenetic dosing. Pharmacogenomics 2009;10:1243-55
    • (2009) Pharmacogenomics , vol.10 , pp. 1243-55
    • Scott, S.A.1    Jaremko, M.2    Lubitz, S.A.3
  • 25
    • 67849126675 scopus 로고    scopus 로고
    • Global variation in CYP2C8-CYP2C9 functional haplotypes
    • Speed WC, Kang SP, Tuck DP, et al. Global variation in CYP2C8-CYP2C9 functional haplotypes. Pharmacogenomics J 2009;9:283-90
    • (2009) Pharmacogenomics J , vol.9 , pp. 283-90
    • Speed, W.C.1    Kang, S.P.2    Tuck, D.P.3
  • 26
    • 84861458604 scopus 로고    scopus 로고
    • Global pharmacogenomics: Impact of population diversity on the distribution of polymorphisms in the CYP2C cluster among Brazilians
    • December 21 online publication doi:10.1038/tpj.2010.89
    • Suarez-Kurtz G, Genro JP, de Moraes MO, et al. Global pharmacogenomics: Impact of population diversity on the distribution of polymorphisms in the CYP2C cluster among Brazilians. Pharmacogenomics J 2010 December 21 online publication doi:10.1038/tpj.2010.89
    • (2010) Pharmacogenomics J
    • Suarez-Kurtz, G.1    Genro, J.P.2    De Moraes, M.O.3
  • 27
    • 70649100416 scopus 로고    scopus 로고
    • Cytochrome P450 2C8 pharmacogenetics: A review of clinical studies
    • Daily EB, Aquilante CL. Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies. Pharmacogenomics 2009;10:1489-510
    • (2009) Pharmacogenomics , vol.10 , pp. 1489-510
    • Daily, E.B.1    Aquilante, C.L.2
  • 30
    • 79953048086 scopus 로고    scopus 로고
    • Impact of CYP2C8 3 on paclitaxel clearance: A population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer
    • Bergmann TK, Brasch-Andersen C, Green H, et al. Impact of CYP2C8 3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer. Pharmacogenomics J 2011;11:113-20
    • (2011) Pharmacogenomics J , vol.11 , pp. 113-20
    • Bergmann, T.K.1    Brasch-Andersen, C.2    Green, H.3
  • 31
    • 33646252500 scopus 로고    scopus 로고
    • Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of paclitaxel in patients with solid tumors
    • Joerger M, Huitema AD, van den Bongard DH, et al. Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of paclitaxel in patients with solid tumors. Clin Cancer Res 2006;12:2150-7
    • (2006) Clin Cancer Res , vol.12 , pp. 2150-7
    • Joerger, M.1    Huitema, A.D.2    Van Den Bongard, D.H.3
  • 32
    • 80051544848 scopus 로고    scopus 로고
    • Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5
    • Kaspera R, Naraharisetti SB, Evangelista EA, et al. Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5. Biochem Pharmacol 2011;82:681-91
    • (2011) Biochem Pharmacol , vol.82 , pp. 681-91
    • Kaspera, R.1    Naraharisetti, S.B.2    Evangelista, E.A.3
  • 33
    • 78149470864 scopus 로고    scopus 로고
    • Polymorphisms of human cytochrome P450 2C9 and the functional relevance
    • Zhou SF, Zhou ZW, Huang M. Polymorphisms of human cytochrome P450 2C9 and the functional relevance. Toxicology 2010;278(2):165-88
    • (2010) Toxicology , vol.278 , Issue.2 , pp. 165-88
    • Zhou, S.F.1    Zhou, Z.W.2    Huang, M.3
  • 34
    • 78649317664 scopus 로고    scopus 로고
    • Linkage disequilibrium between the CYP2C19 17 allele and wildtype CYP2C8 and CYP2C9 alleles: Identification of CYP2C haplotypes in healthy Nordic populations
    • Pedersen RS, Brasch-Andersen C, Sim SC, et al. Linkage disequilibrium between the CYP2C19 17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations. Eur J Clin Pharmacol 2010;66:1199-205
    • (2010) Eur J Clin Pharmacol , vol.66 , pp. 1199-205
    • Pedersen, R.S.1    Brasch-Andersen, C.2    Sim, S.C.3
  • 35
    • 60549095814 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 genetic polymorphisms in Ugandans
    • Miura J, Obua C, Abbo C, et al. Cytochrome P450 2C19 genetic polymorphisms in Ugandans. Eur J Clin Pharmacol 2009;65:319-20
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 319-20
    • Miura, J.1    Obua, C.2    Abbo, C.3
  • 37
    • 76649115043 scopus 로고    scopus 로고
    • Pharmacogenetics of CYP2C19: Functional and clinical implications of a new variant CYP2C19 17
    • Li-Wan-Po A, Girard T, Farndon P, et al. Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19 17. Br J Clin Pharmacol 2010;69:222-30
    • (2010) Br J Clin Pharmacol , vol.69 , pp. 222-30
    • Li-Wan-Po, A.1    Girard, T.2    Farndon, P.3
  • 38
    • 82955212922 scopus 로고    scopus 로고
    • Genetic determinants of platelet response to clopidogrel
    • Kubica A, Kozinski M, Grzesk G, et al. Genetic determinants of platelet response to clopidogrel. J Thromb Thrombolysis 2011;32:459-66
    • (2011) J Thromb Thrombolysis , vol.32 , pp. 459-66
    • Kubica, A.1    Kozinski, M.2    Grzesk, G.3
  • 39
    • 61349191612 scopus 로고    scopus 로고
    • Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis
    • Giusti B, Gori AM, Marcucci R, et al. Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis. Am J Cardiol 2009;103:806-11
    • (2009) Am J Cardiol , vol.103 , pp. 806-11
    • Giusti, B.1    Gori, A.M.2    Marcucci, R.3
  • 40
    • 57549092687 scopus 로고    scopus 로고
    • The pharmacogenetics and pharmacodynamics of clopidogrel response: An analysis from the PRINC (Plavix Response in Coronary Intervention) trial
    • Gladding P, Webster M, Zeng I, et al. The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial. JACC Cardiovasc Interv 2008;1:620-7
    • (2008) JACC Cardiovasc Interv , vol.1 , pp. 620-7
    • Gladding, P.1    Webster, M.2    Zeng, I.3
  • 41
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009;360:354-62
    • (2009) N Engl J Med , vol.360 , pp. 354-62
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 42
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
    • Shuldiner AR, OConnell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. Jama 2009;302:849-57
    • (2009) Jama , vol.302 , pp. 849-57
    • Shuldiner, A.R.1    Oconnell, J.R.2    Bliden, K.P.3
  • 43
    • 65249145201 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
    • Sibbing D, Stegherr J, Latz W, et al. Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention. Eur Heart J 2009;30:916-22
    • (2009) Eur Heart J , vol.30 , pp. 916-22
    • Sibbing, D.1    Stegherr, J.2    Latz, W.3
  • 44
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009;360:363-75
    • (2009) N Engl J Med , vol.360 , pp. 363-75
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 46
    • 84858999257 scopus 로고    scopus 로고
    • Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: Systematic review and meta-analysis
    • Bauer T, Bouman HJ, van Werkum JW, et al. Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis. BMJ 2011;343:d4588
    • (2011) BMJ , vol.343
    • Bauer, T.1    Bouman, H.J.2    Van Werkum, J.W.3
  • 47
    • 79952623482 scopus 로고    scopus 로고
    • Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes
    • Singh MS, Francis PA, Michael M. Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes. Breast 2011;20:111-18
    • (2011) Breast , vol.20 , pp. 111-18
    • Singh, M.S.1    Francis, P.A.2    Michael, M.3
  • 48
    • 84856227640 scopus 로고    scopus 로고
    • Lack of any association between functionally significant CYP2D6 polymorphisms and clinical outcomes in early breast cancer patients receiving adjuvant tamoxifen treatment
    • Park IH, Ro J, Park S, et al. Lack of any association between functionally significant CYP2D6 polymorphisms and clinical outcomes in early breast cancer patients receiving adjuvant tamoxifen treatment. Breast Cancer Res Treat 2012;131(2):455-61
    • (2012) Breast Cancer Res Treat , vol.131 , Issue.2 , pp. 455-61
    • Park, I.H.1    Ro, J.2    Park, S.3
  • 50
    • 33746102723 scopus 로고    scopus 로고
    • CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: Implications for clinical practice and genetic testing
    • DOI 10.1038/sj.tpj.6500378, PII 6500378
    • Cai WM, Nikoloff DM, Pan RM, et al. CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: implications for clinical practice and genetic testing. Pharmacogenomics J 2006;6:343-50 (Pubitemid 44480154)
    • (2006) Pharmacogenomics Journal , vol.6 , Issue.5 , pp. 343-350
    • Cai, W.-M.1    Nikoloff, D.M.2    Pan, R.-M.3    De Leon, J.4    Fanti, P.5    Fairchild, M.6    Koch, W.H.7    Wedlund, P.J.8
  • 51
    • 75749116800 scopus 로고    scopus 로고
    • Genetic polymorphism in cytochrome P450 2D6 (CYP2D6): Population distribution of CYP2D6 activity
    • Neafsey P, Ginsberg G, Hattis D, et al. Genetic polymorphism in cytochrome P450 2D6 (CYP2D6): population distribution of CYP2D6 activity. J Toxicol Environ Health B Crit Rev 2009;12:334-61
    • (2009) J Toxicol Environ Health B Crit Rev , vol.12 , pp. 334-61
    • Neafsey, P.1    Ginsberg, G.2    Hattis, D.3
  • 52
    • 59549103789 scopus 로고    scopus 로고
    • Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales
    • Sistonen J, Fuselli S, Palo JU, et al. Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales. Pharmacogenet Genomics 2009;19:170-9
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 170-9
    • Sistonen, J.1    Fuselli, S.2    Palo, J.U.3
  • 53
    • 33645839857 scopus 로고    scopus 로고
    • Identification and characterization of CYP3A4 20, a novel rare CYP3A4 allele without functional activity
    • Westlind-Johnsson A, Hermann R, Huennemeyer A, et al. Identification and characterization of CYP3A4 20, a novel rare CYP3A4 allele without functional activity. Clin Pharmacol Ther 2006;79:339-49
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 339-49
    • Westlind-Johnsson, A.1    Hermann, R.2    Huennemeyer, A.3
  • 54
    • 0742321734 scopus 로고    scopus 로고
    • Human drug metabolising cytochrome P450 enzymes: Properties and polymorphisms
    • DOI 10.1007/s00210-003-0819-z
    • Ingelman-Sundberg M. Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms. Naunyn Schmiedebergs Arch Pharmacol 2004;369:89-104 (Pubitemid 38161226)
    • (2004) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.369 , Issue.1 , pp. 89-104
    • Ingelman-Sundberg, M.1
  • 55
    • 70649093023 scopus 로고    scopus 로고
    • Pharmacogenomics of CYP3A: Considerations for HIV treatment
    • Lakhman SS, Ma Q, Morse GD. Pharmacogenomics of CYP3A: considerations for HIV treatment. Pharmacogenomics 2009;10:1323-39
    • (2009) Pharmacogenomics , vol.10 , pp. 1323-39
    • Lakhman, S.S.1    Ma, Q.2    Morse, G.D.3
  • 56
    • 36749017545 scopus 로고    scopus 로고
    • Drugs as CYP3A probes, inducers, and inhibitors
    • Liu YT, Hao HP, Liu CX, et al. Drugs as CYP3A probes, inducers, and inhibitors. Drug Metab Rev 2007;39:699-721
    • (2007) Drug Metab Rev , vol.39 , pp. 699-721
    • Liu, Y.T.1    Hao, H.P.2    Liu, C.X.3
  • 57
  • 61
    • 80054924410 scopus 로고    scopus 로고
    • A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients
    • Elens L, Bouamar R, Hesselink DA, et al. A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients. Clin Chem 2011;57(11):1574-83
    • (2011) Clin Chem , vol.57 , Issue.11 , pp. 1574-83
    • Elens, L.1    Bouamar, R.2    Hesselink, D.A.3
  • 62
    • 13544267712 scopus 로고    scopus 로고
    • Cytochrome P450 3A polymorphisms and immunosuppressive drugs
    • DOI 10.1517/14622416.6.1.37
    • Thervet E, Legendre C, Beaune P, et al. Cytochrome P450 3A polymorphisms and immunosuppressive drugs. Pharmacogenomics 2005;6:37-47 (Pubitemid 40220669)
    • (2005) Pharmacogenomics , vol.6 , Issue.1 , pp. 37-47
    • Thervet, E.1    Legendre, C.2    Beaune, P.3    Anglicheau, D.4
  • 63
    • 79960633918 scopus 로고    scopus 로고
    • Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
    • Wang D, Guo Y, Wrighton SA, et al. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. Pharmacogenomics J 2011;11:274-86
    • (2011) Pharmacogenomics J , vol.11 , pp. 274-86
    • Wang, D.1    Guo, Y.2    Wrighton, S.A.3
  • 68
    • 0037291512 scopus 로고    scopus 로고
    • Nicotine metabolism, human drug metabolism polymorphisms, and smoking behaviour
    • DOI 10.1016/S0300-483X(02)00513-9, PII S0300483X02005139
    • Tricker AR. Nicotine metabolism, human drug metabolism polymorphisms, and smoking behaviour. Toxicology 2003;183:151-73 (Pubitemid 36005395)
    • (2003) Toxicology , vol.183 , Issue.1-3 , pp. 151-173
    • Tricker, A.R.1
  • 69
  • 70
    • 77949615790 scopus 로고    scopus 로고
    • New CYP2A6 gene deletion and conversion variants in a population of Black African descent
    • Mwenifumbo JC, Zhou Q, Benowitz NL, et al. New CYP2A6 gene deletion and conversion variants in a population of Black African descent. Pharmacogenomics 2010;11:189-98
    • (2010) Pharmacogenomics , vol.11 , pp. 189-98
    • Mwenifumbo, J.C.1    Zhou, Q.2    Benowitz, N.L.3
  • 71
    • 33744968881 scopus 로고    scopus 로고
    • Adolescent nicotine metabolism: Ethnoracial differences among dependent smokers
    • Moolchan ET, Franken FH, Jaszyna-Gasior M. Adolescent nicotine metabolism: ethnoracial differences among dependent smokers. Ethn Dis 2006;16:239-43 (Pubitemid 46959274)
    • (2006) Ethnicity and Disease , vol.16 , Issue.1 , pp. 239-243
    • Moolchan, E.T.1    Franken, F.H.2    Jaszyna-Gasior, M.3
  • 72
    • 0036444114 scopus 로고    scopus 로고
    • Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6
    • Nakajima M, Kuroiwa Y, Yokoi T. Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6. Drug Metab Rev 2002;34:865-77
    • (2002) Drug Metab Rev , vol.34 , pp. 865-77
    • Nakajima, M.1    Kuroiwa, Y.2    Yokoi, T.3
  • 73
    • 4644255903 scopus 로고    scopus 로고
    • Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians
    • DOI 10.1097/00008571-200409000-00006
    • Schoedel KA, Hoffmann EB, Rao Y, et al. Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians. Pharmacogenetics 2004;14:615-26 (Pubitemid 39281816)
    • (2004) Pharmacogenetics , vol.14 , Issue.9 , pp. 615-626
    • Schoedel, K.A.1    Hoffmann, E.B.2    Rao, Y.3    Sellers, E.M.4    Tyndale, R.F.5
  • 74
    • 33646062273 scopus 로고    scopus 로고
    • Specific human CYP 450 isoform metabolism of a pentachlorobiphenyl (PCB-IUPAC# 101)
    • McGraw JE Sr, Waller DP. Specific human CYP 450 isoform metabolism of a pentachlorobiphenyl (PCB-IUPAC# 101). Biochem Biophys Res Commun 2006;344:129-33
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 129-33
    • McGraw, Sr.J.E.1    Waller, D.P.2
  • 75
    • 57149142497 scopus 로고    scopus 로고
    • The role of African American ethnicity and metabolism in sentinel polychlorinated biphenyl congener serum levels
    • McGraw JE, Waller DP. The role of African American ethnicity and metabolism in sentinel polychlorinated biphenyl congener serum levels. Environ Toxicol Pharmacol 2009;27:54-61
    • (2009) Environ Toxicol Pharmacol , vol.27 , pp. 54-61
    • McGraw, J.E.1    Waller, D.P.2
  • 76
    • 52449133102 scopus 로고    scopus 로고
    • CYP2B6: New insights into a historically overlooked cytochrome P450 isozyme
    • Wang H, Tompkins LM. CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Curr Drug Metab 2008;9:598-610
    • (2008) Curr Drug Metab , vol.9 , pp. 598-610
    • Wang, H.1    Tompkins, L.M.2
  • 80
    • 33750592308 scopus 로고    scopus 로고
    • Intraand inter-ethnic differences in the allele frequencies of cytochrome P450 2B6 gene in Chinese
    • Guan S, Huang M, Li X, et al. Intraand inter-ethnic differences in the allele frequencies of cytochrome P450 2B6 gene in Chinese. Pharm Res 2006;23:1983-90
    • (2006) Pharm Res , vol.23 , pp. 1983-90
    • Guan, S.1    Huang, M.2    Li, X.3
  • 81
    • 67649177436 scopus 로고    scopus 로고
    • Plasma efavirenz concentrations and the association with CYP2B6-516G > T polymorphism in HIV-infected Thai children
    • Puthanakit T, Tanpaiboon P, Aurpibul L, et al. Plasma efavirenz concentrations and the association with CYP2B6-516G > T polymorphism in HIV-infected Thai children. Antivir Ther 2009;14:315-20
    • (2009) Antivir Ther , vol.14 , pp. 315-20
    • Puthanakit, T.1    Tanpaiboon, P.2    Aurpibul, L.3
  • 82
    • 62549089177 scopus 로고    scopus 로고
    • Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine
    • Ramachandran G, Ramesh K, Hemanth Kumar AK, et al. Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine. J Antimicrob Chemother 2009;63:841-3
    • (2009) J Antimicrob Chemother , vol.63 , pp. 841-3
    • Ramachandran, G.1    Ramesh, K.2    Hemanth Kumar, A.K.3
  • 83
    • 62549099045 scopus 로고    scopus 로고
    • Pharmacogenomics of CYP2A6 CYP2B6 CYP2C19 CYP2D6 CYP3A4 CYP3A5 and MDR1 in Vietnam
    • Veiga MI, Asimus S, Ferreira PE, et al. Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam. Eur J Clin Pharmacol 2009;65:355-63
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 355-63
    • Veiga, M.I.1    Asimus, S.2    Ferreira, P.E.3
  • 84
    • 34248998418 scopus 로고    scopus 로고
    • Genetic variability of CYP2B6 polymorphisms in four southern Chinese populations
    • Xu BY, Guo LP, Lee SS, et al. Genetic variability of CYP2B6 polymorphisms in four southern Chinese populations. World J Gastroenterol 2007;13:2100-3
    • (2007) World J Gastroenterol , vol.13 , pp. 2100-3
    • Xu, B.Y.1    Guo, L.P.2    Lee, S.S.3
  • 85
    • 33750454425 scopus 로고    scopus 로고
    • Pyrosequencing-based screening for genetic polymorphisms in cytochrome P450 2B6 of potential clinical relevance
    • DOI 10.2217/14622416.7.7.995
    • Rohrbacher M, Kirchhof A, Geisslinger G, et al. Pyrosequencing-based screening for genetic polymorphisms in cytochrome P450 2B6 of potential clinical relevance. Pharmacogenomics 2006;7:995-1002 (Pubitemid 44644779)
    • (2006) Pharmacogenomics , vol.7 , Issue.7 , pp. 995-1002
    • Rohrbacher, M.1    Kirchhof, A.2    Geisslinger, G.3    Lotsch, J.4
  • 86
    • 73349108767 scopus 로고    scopus 로고
    • Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2
    • Zhou SF, Yang LP, Zhou ZW, et al. Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2. Aaps J 2009;11:481-94
    • (2009) Aaps J , vol.11 , pp. 481-94
    • Zhou, S.F.1    Yang, L.P.2    Zhou, Z.W.3
  • 87
    • 41549109042 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme polymorphism frequency in indigenous and native American populations: A systematic review
    • DOI 10.1159/000113876
    • Jaja C, Burke W, Thummel K, et al. Cytochrome p450 enzyme polymorphism frequency in indigenous and native American populations: a systematic review. Community Genet 2008;11:141-9 (Pubitemid 351465617)
    • (2008) Community Genetics , vol.11 , Issue.3 , pp. 141-149
    • Jaja, C.1    Burke, W.2    Thummel, K.3    Edwards, K.4    Veenstra, D.L.5
  • 88
    • 0036223831 scopus 로고    scopus 로고
    • Summary of information on human CYP enzymes: Human P450 metabolism data
    • DOI 10.1081/DMR-120001392
    • Rendic S. Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev 2002;34(1-2):83-448 (Pubitemid 34311090)
    • (2002) Drug Metabolism Reviews , vol.34 , Issue.1-2 , pp. 83-448
    • Rendic, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.