-
4
-
-
53349095856
-
Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa
-
Yaeger R, Avila-Bront A, Abdul K, et al. Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev 2008;17:1329-38
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 1329-38
-
-
Yaeger, R.1
Avila-Bront, A.2
Abdul, K.3
-
5
-
-
84857248363
-
-
American Society of Health-System Pharmacists; Bethesda, MD
-
Zdanowicz. Concepts in Pharmacogenomics. American Society of Health-System Pharmacists; Bethesda, MD; 2010
-
(2010)
Concepts in Pharmacogenomics
-
-
Zdanowicz1
-
6
-
-
84857248351
-
-
August14 Cited 29 August 2010
-
Nelson D. The Cytochrome P450 Homepage. 2009.August14 2009.Available from: http://drnelson. uthsc.edu/human.P450.table.html [Cited 29 August 2010]
-
(2009)
The Cytochrome P450 Homepage
, vol.2009
-
-
Nelson, D.1
-
7
-
-
33745668685
-
Role of CYP pharmacogenetics and drug-drug interactions in the efficacy and safety of atypical and other antipsychotic agents
-
DOI 10.1211/jpp.58.7.0001
-
Murray M. Role of CYP pharmacogenetics and drug-drug interactions in the efficacy and safety of atypical and other antipsychotic agents. J Pharm Pharmacol 2006;58:871-85 (Pubitemid 43967103)
-
(2006)
Journal of Pharmacy and Pharmacology
, vol.58
, Issue.7
, pp. 871-885
-
-
Murray, M.1
-
8
-
-
75549086408
-
SuperCYP: A comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions
-
Preissner S, Kroll K, Dunkel M, et al. SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res 2009;38:D237-43
-
(2009)
Nucleic Acids Res
, vol.38
-
-
Preissner, S.1
Kroll, K.2
Dunkel, M.3
-
9
-
-
1642494659
-
"Cocktail" Approaches and Strategies in Drug Development: Valuable Tool or Flawed Science?
-
DOI 10.1177/0091270003261333
-
Zhou H, Tong Z, McLeod JF. "Cocktail" approaches and strategies in drug development: valuable tool or flawed science? J Clin Pharmacol 2004;44:120-34 (Pubitemid 38114310)
-
(2004)
Journal of Clinical Pharmacology
, vol.44
, Issue.2
, pp. 120-134
-
-
Zhou, H.1
Tong, Z.2
McLeod, J.F.3
-
11
-
-
44949222437
-
Variation in CYP1A2 activity and its clinical implications: Influence of environmental factors and genetic polymorphisms
-
DOI 10.2217/14622416.9.5.625
-
Gunes A, Dahl ML. Variation in CYP1A2 activity and its clinical implications: influence of environmental factors and genetic polymorphisms. Pharmacogenomics 2008;9:625-37 (Pubitemid 351803920)
-
(2008)
Pharmacogenomics
, vol.9
, Issue.5
, pp. 625-637
-
-
Gunes, A.1
Dahl, M.-L.2
-
12
-
-
70149110672
-
Polymorphism of human cytochrome P450 enzymes and its clinical impact
-
Zhou SF, Liu JP, Chowbay B. Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metab Rev 2009;41:89-295
-
(2009)
Drug Metab Rev
, vol.41
, pp. 89-295
-
-
Zhou, S.F.1
Liu, J.P.2
Chowbay, B.3
-
13
-
-
0042856457
-
Genetic polymorphism of CYP1A2 in ethiopians affecting induction and expression: Characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1
-
DOI 10.1124/mol.64.3.659
-
Aklillu E, Carrillo JA, Makonnen E, et al. Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1. Mol Pharmacol 2003;64:659-69 (Pubitemid 37048569)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.3
, pp. 659-669
-
-
Aklillu, E.1
Carrillo, J.A.2
Makonnen, E.3
Hellman, K.4
Pitarque, M.5
Bertilsson, L.6
Ingelman-Sundberg, M.7
-
14
-
-
0036433001
-
Inducibility of CYP1A2 by omeprazole in vivo related to the genetic polymorphism of CYP1A2
-
Han XM, Ouyang DS, Chen XP, et al. Inducibility of CYP1A2 by omeprazole in vivo related to the genetic polymorphism of CYP1A2. Br J Clin Pharmacol 2002;54:540-3
-
(2002)
Br J Clin Pharmacol
, vol.54
, pp. 540-3
-
-
Han, X.M.1
Ouyang, D.S.2
Chen, X.P.3
-
15
-
-
0032908778
-
Functional significance of a CA polymorphism in intron I of the cytochrome P450 CYP1A2 gene tested with caffeine
-
DOI 10.1046/j.1365-2125.1999.00898.x
-
Sachse C, Brockmoller J, Bauer S, et al. Functional significance of a C- > A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol 1999;47:445-9 (Pubitemid 29161279)
-
(1999)
British Journal of Clinical Pharmacology
, vol.47
, Issue.4
, pp. 445-449
-
-
Sachse, C.1
Brockmoller, J.2
Bauer, S.3
Roots, I.4
-
16
-
-
33747097516
-
Coffee, myocardial infarction, and CYP nomenclature [4]
-
DOI 10.1001/jama.296.7.764-b
-
Ingelman-Sundberg M, Sim SC, Nebert DW. Coffee, myocardial infarction, and CYP nomenclature. Jama 2006;296:764-5.author reply 65-6 (Pubitemid 44223097)
-
(2006)
Journal of the American Medical Association
, vol.296
, Issue.7
, pp. 764-765
-
-
Ingelman-Sundberg, M.1
Sim, S.C.2
Nebert, D.W.3
-
17
-
-
33644792595
-
Coffee, CYP1A2 genotype, and risk of myocardial infarction
-
DOI 10.1001/jama.295.10.1135
-
Cornelis MC, El-Sohemy A, Kabagambe EK, et al. Coffee, CYP1A2 genotype, and risk of myocardial infarction. Jama 2006;295:1135-41 (Pubitemid 43352342)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.10
, pp. 1135-1141
-
-
Cornelis, M.C.1
El-Sohemy, A.2
Kabagambe, E.K.3
Campos, H.4
-
18
-
-
78049268075
-
Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine
-
Gentile G, Borro M, Lala N, et al. Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine. J Headache Pain 2010;11:431-5
-
(2010)
J Headache Pain
, vol.11
, pp. 431-5
-
-
Gentile, G.1
Borro, M.2
Lala, N.3
-
19
-
-
75549088045
-
Pharmacogenetics and olanzapine treatment: CYP1A2 1F and serotonergic polymorphisms influence therapeutic outcome
-
Laika B, Leucht S, Heres S, et al. Pharmacogenetics and olanzapine treatment: CYP1A2 1F and serotonergic polymorphisms influence therapeutic outcome. Pharmacogenomics J 2010;10:20-9
-
(2010)
Pharmacogenomics J
, vol.10
, pp. 20-9
-
-
Laika, B.1
Leucht, S.2
Heres, S.3
-
20
-
-
50849104253
-
Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients
-
Bohanec Grabar P, Rozman B, Tomsic M, et al. Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. Eur J Clin Pharmacol 2008;64:871-6
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 871-6
-
-
Bohanec Grabar, P.1
Rozman, B.2
Tomsic, M.3
-
21
-
-
72949119743
-
Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6
-
Mo SL, Liu YH, Duan W, et al. Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. Curr Drug Metab 2009;10:730-53
-
(2009)
Curr Drug Metab
, vol.10
, pp. 730-53
-
-
Mo, S.L.1
Liu, Y.H.2
Duan, W.3
-
22
-
-
33646205301
-
Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals
-
Garcia-Martin E, Martinez C, Ladero JM, et al. Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals. Mol Diagn Ther 2006;10:29-40
-
(2006)
Mol Diagn Ther
, vol.10
, pp. 29-40
-
-
Garcia-Martin, E.1
Martinez, C.2
Ladero, J.M.3
-
23
-
-
34249823331
-
Influence of CYP2C9 genotype on warfarin dose among African-Americans and European-Americans
-
DOI 10.2217/17410541.4.2.157
-
Limdi N, Goldstein J, Blaisdell J, et al. Influence of CYP2C9 Genotype on warfarin dose among African American and European Americans. Per Med 2007;4:157-69 (Pubitemid 46845895)
-
(2007)
Personalized Medicine
, vol.4
, Issue.2
, pp. 157-169
-
-
Limdi, N.A.1
Goldstein, J.A.2
Blaisdell, J.A.3
Beasley, T.M.4
Rivers, C.A.5
Acton, R.T.6
-
24
-
-
70649111382
-
CYP2C9 8 is prevalent among African- Americans: Implications for pharmacogenetic dosing
-
Scott SA, Jaremko M, Lubitz SA, et al. CYP2C9 8 is prevalent among African- Americans: implications for pharmacogenetic dosing. Pharmacogenomics 2009;10:1243-55
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1243-55
-
-
Scott, S.A.1
Jaremko, M.2
Lubitz, S.A.3
-
25
-
-
67849126675
-
Global variation in CYP2C8-CYP2C9 functional haplotypes
-
Speed WC, Kang SP, Tuck DP, et al. Global variation in CYP2C8-CYP2C9 functional haplotypes. Pharmacogenomics J 2009;9:283-90
-
(2009)
Pharmacogenomics J
, vol.9
, pp. 283-90
-
-
Speed, W.C.1
Kang, S.P.2
Tuck, D.P.3
-
26
-
-
84861458604
-
Global pharmacogenomics: Impact of population diversity on the distribution of polymorphisms in the CYP2C cluster among Brazilians
-
December 21 online publication doi:10.1038/tpj.2010.89
-
Suarez-Kurtz G, Genro JP, de Moraes MO, et al. Global pharmacogenomics: Impact of population diversity on the distribution of polymorphisms in the CYP2C cluster among Brazilians. Pharmacogenomics J 2010 December 21 online publication doi:10.1038/tpj.2010.89
-
(2010)
Pharmacogenomics J
-
-
Suarez-Kurtz, G.1
Genro, J.P.2
De Moraes, M.O.3
-
27
-
-
70649100416
-
Cytochrome P450 2C8 pharmacogenetics: A review of clinical studies
-
Daily EB, Aquilante CL. Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies. Pharmacogenomics 2009;10:1489-510
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1489-510
-
-
Daily, E.B.1
Aquilante, C.L.2
-
28
-
-
34548081331
-
Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer
-
DOI 10.1038/sj.tpj.6500434, PII 6500434
-
Marsh S, Somlo G, Li X, et al. Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer. Pharmacogenomics J 2007;7:362-5 (Pubitemid 47484774)
-
(2007)
Pharmacogenomics Journal
, vol.7
, Issue.5
, pp. 362-365
-
-
Marsh, S.1
Somlo, G.2
Li, X.3
Frankel, P.4
King, C.R.5
Shannon, W.D.6
McLeod, H.L.7
Synold, T.W.8
-
29
-
-
28144461394
-
Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 polymorphisms with the pharmacokinetics of paclitaxel
-
DOI 10.1158/1078-0432.CCR-05-1152
-
Henningsson A, Marsh S, Loos WJ, et al. Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 polymorphisms with the pharmacokinetics of paclitaxel. Clin Cancer Res 2005;11:8097-104 (Pubitemid 41698753)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.22
, pp. 8097-8104
-
-
Henningsson, A.1
Marsh, S.2
Loos, W.J.3
Karlsson, M.O.4
Garsa, A.5
Mross, K.6
Mielke, S.7
Vigano, L.8
Locatelli, A.9
Verweij, J.10
Sparreboom, A.11
McLeod, H.L.12
-
30
-
-
79953048086
-
Impact of CYP2C8 3 on paclitaxel clearance: A population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer
-
Bergmann TK, Brasch-Andersen C, Green H, et al. Impact of CYP2C8 3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer. Pharmacogenomics J 2011;11:113-20
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 113-20
-
-
Bergmann, T.K.1
Brasch-Andersen, C.2
Green, H.3
-
31
-
-
33646252500
-
Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of paclitaxel in patients with solid tumors
-
Joerger M, Huitema AD, van den Bongard DH, et al. Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of paclitaxel in patients with solid tumors. Clin Cancer Res 2006;12:2150-7
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2150-7
-
-
Joerger, M.1
Huitema, A.D.2
Van Den Bongard, D.H.3
-
32
-
-
80051544848
-
Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5
-
Kaspera R, Naraharisetti SB, Evangelista EA, et al. Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5. Biochem Pharmacol 2011;82:681-91
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 681-91
-
-
Kaspera, R.1
Naraharisetti, S.B.2
Evangelista, E.A.3
-
33
-
-
78149470864
-
Polymorphisms of human cytochrome P450 2C9 and the functional relevance
-
Zhou SF, Zhou ZW, Huang M. Polymorphisms of human cytochrome P450 2C9 and the functional relevance. Toxicology 2010;278(2):165-88
-
(2010)
Toxicology
, vol.278
, Issue.2
, pp. 165-88
-
-
Zhou, S.F.1
Zhou, Z.W.2
Huang, M.3
-
34
-
-
78649317664
-
Linkage disequilibrium between the CYP2C19 17 allele and wildtype CYP2C8 and CYP2C9 alleles: Identification of CYP2C haplotypes in healthy Nordic populations
-
Pedersen RS, Brasch-Andersen C, Sim SC, et al. Linkage disequilibrium between the CYP2C19 17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations. Eur J Clin Pharmacol 2010;66:1199-205
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 1199-205
-
-
Pedersen, R.S.1
Brasch-Andersen, C.2
Sim, S.C.3
-
35
-
-
60549095814
-
Cytochrome P450 2C19 genetic polymorphisms in Ugandans
-
Miura J, Obua C, Abbo C, et al. Cytochrome P450 2C19 genetic polymorphisms in Ugandans. Eur J Clin Pharmacol 2009;65:319-20
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 319-20
-
-
Miura, J.1
Obua, C.2
Abbo, C.3
-
36
-
-
30344457586
-
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
-
DOI 10.1016/j.clpt.2005.10.002, PII S0009923605004613
-
Sim SC, Risinger C, Dahl ML, et al. A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther 2006;79:103-13 (Pubitemid 43069582)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.79
, Issue.1
, pp. 103-113
-
-
Sim, S.C.1
Risinger, C.2
Dahl, M.-L.3
Aklillu, E.4
Christensen, M.5
Bertilsson, L.6
Ingelman-Sundberg, M.7
-
37
-
-
76649115043
-
Pharmacogenetics of CYP2C19: Functional and clinical implications of a new variant CYP2C19 17
-
Li-Wan-Po A, Girard T, Farndon P, et al. Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19 17. Br J Clin Pharmacol 2010;69:222-30
-
(2010)
Br J Clin Pharmacol
, vol.69
, pp. 222-30
-
-
Li-Wan-Po, A.1
Girard, T.2
Farndon, P.3
-
38
-
-
82955212922
-
Genetic determinants of platelet response to clopidogrel
-
Kubica A, Kozinski M, Grzesk G, et al. Genetic determinants of platelet response to clopidogrel. J Thromb Thrombolysis 2011;32:459-66
-
(2011)
J Thromb Thrombolysis
, vol.32
, pp. 459-66
-
-
Kubica, A.1
Kozinski, M.2
Grzesk, G.3
-
39
-
-
61349191612
-
Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis
-
Giusti B, Gori AM, Marcucci R, et al. Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis. Am J Cardiol 2009;103:806-11
-
(2009)
Am J Cardiol
, vol.103
, pp. 806-11
-
-
Giusti, B.1
Gori, A.M.2
Marcucci, R.3
-
40
-
-
57549092687
-
The pharmacogenetics and pharmacodynamics of clopidogrel response: An analysis from the PRINC (Plavix Response in Coronary Intervention) trial
-
Gladding P, Webster M, Zeng I, et al. The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial. JACC Cardiovasc Interv 2008;1:620-7
-
(2008)
JACC Cardiovasc Interv
, vol.1
, pp. 620-7
-
-
Gladding, P.1
Webster, M.2
Zeng, I.3
-
41
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009;360:354-62
-
(2009)
N Engl J Med
, vol.360
, pp. 354-62
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
-
42
-
-
69249219296
-
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
-
Shuldiner AR, OConnell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. Jama 2009;302:849-57
-
(2009)
Jama
, vol.302
, pp. 849-57
-
-
Shuldiner, A.R.1
Oconnell, J.R.2
Bliden, K.P.3
-
43
-
-
65249145201
-
Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
-
Sibbing D, Stegherr J, Latz W, et al. Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention. Eur Heart J 2009;30:916-22
-
(2009)
Eur Heart J
, vol.30
, pp. 916-22
-
-
Sibbing, D.1
Stegherr, J.2
Latz, W.3
-
44
-
-
58749090547
-
Genetic determinants of response to clopidogrel and cardiovascular events
-
Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009;360:363-75
-
(2009)
N Engl J Med
, vol.360
, pp. 363-75
-
-
Simon, T.1
Verstuyft, C.2
Mary-Krause, M.3
-
45
-
-
43049179414
-
Cytochrome P450 2C19 681G>A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents
-
DOI 10.1016/j.jacc.2007.12.056, PII S0735109708008656
-
Trenk D, Hochholzer W, Fromm MF, et al. Cytochrome P450 2C19 681G > A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug- eluting or bare-metal stents. J Am Coll Cardiol 2008;51:1925-34 (Pubitemid 351636443)
-
(2008)
Journal of the American College of Cardiology
, vol.51
, Issue.20
, pp. 1925-1934
-
-
Trenk, D.1
Hochholzer, W.2
Fromm, M.F.3
Chialda, L.-E.4
Pahl, A.5
Valina, C.M.6
Stratz, C.7
Schmiebusch, P.8
Bestehorn, H.-P.9
Buttner, H.J.10
Neumann, F.-J.11
-
46
-
-
84858999257
-
Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: Systematic review and meta-analysis
-
Bauer T, Bouman HJ, van Werkum JW, et al. Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis. BMJ 2011;343:d4588
-
(2011)
BMJ
, vol.343
-
-
Bauer, T.1
Bouman, H.J.2
Van Werkum, J.W.3
-
47
-
-
79952623482
-
Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes
-
Singh MS, Francis PA, Michael M. Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes. Breast 2011;20:111-18
-
(2011)
Breast
, vol.20
, pp. 111-18
-
-
Singh, M.S.1
Francis, P.A.2
Michael, M.3
-
48
-
-
84856227640
-
Lack of any association between functionally significant CYP2D6 polymorphisms and clinical outcomes in early breast cancer patients receiving adjuvant tamoxifen treatment
-
Park IH, Ro J, Park S, et al. Lack of any association between functionally significant CYP2D6 polymorphisms and clinical outcomes in early breast cancer patients receiving adjuvant tamoxifen treatment. Breast Cancer Res Treat 2012;131(2):455-61
-
(2012)
Breast Cancer Res Treat
, vol.131
, Issue.2
, pp. 455-61
-
-
Park, I.H.1
Ro, J.2
Park, S.3
-
50
-
-
33746102723
-
CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: Implications for clinical practice and genetic testing
-
DOI 10.1038/sj.tpj.6500378, PII 6500378
-
Cai WM, Nikoloff DM, Pan RM, et al. CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: implications for clinical practice and genetic testing. Pharmacogenomics J 2006;6:343-50 (Pubitemid 44480154)
-
(2006)
Pharmacogenomics Journal
, vol.6
, Issue.5
, pp. 343-350
-
-
Cai, W.-M.1
Nikoloff, D.M.2
Pan, R.-M.3
De Leon, J.4
Fanti, P.5
Fairchild, M.6
Koch, W.H.7
Wedlund, P.J.8
-
51
-
-
75749116800
-
Genetic polymorphism in cytochrome P450 2D6 (CYP2D6): Population distribution of CYP2D6 activity
-
Neafsey P, Ginsberg G, Hattis D, et al. Genetic polymorphism in cytochrome P450 2D6 (CYP2D6): population distribution of CYP2D6 activity. J Toxicol Environ Health B Crit Rev 2009;12:334-61
-
(2009)
J Toxicol Environ Health B Crit Rev
, vol.12
, pp. 334-61
-
-
Neafsey, P.1
Ginsberg, G.2
Hattis, D.3
-
52
-
-
59549103789
-
Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales
-
Sistonen J, Fuselli S, Palo JU, et al. Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales. Pharmacogenet Genomics 2009;19:170-9
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 170-9
-
-
Sistonen, J.1
Fuselli, S.2
Palo, J.U.3
-
53
-
-
33645839857
-
Identification and characterization of CYP3A4 20, a novel rare CYP3A4 allele without functional activity
-
Westlind-Johnsson A, Hermann R, Huennemeyer A, et al. Identification and characterization of CYP3A4 20, a novel rare CYP3A4 allele without functional activity. Clin Pharmacol Ther 2006;79:339-49
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 339-49
-
-
Westlind-Johnsson, A.1
Hermann, R.2
Huennemeyer, A.3
-
54
-
-
0742321734
-
Human drug metabolising cytochrome P450 enzymes: Properties and polymorphisms
-
DOI 10.1007/s00210-003-0819-z
-
Ingelman-Sundberg M. Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms. Naunyn Schmiedebergs Arch Pharmacol 2004;369:89-104 (Pubitemid 38161226)
-
(2004)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.369
, Issue.1
, pp. 89-104
-
-
Ingelman-Sundberg, M.1
-
55
-
-
70649093023
-
Pharmacogenomics of CYP3A: Considerations for HIV treatment
-
Lakhman SS, Ma Q, Morse GD. Pharmacogenomics of CYP3A: considerations for HIV treatment. Pharmacogenomics 2009;10:1323-39
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1323-39
-
-
Lakhman, S.S.1
Ma, Q.2
Morse, G.D.3
-
56
-
-
36749017545
-
Drugs as CYP3A probes, inducers, and inhibitors
-
Liu YT, Hao HP, Liu CX, et al. Drugs as CYP3A probes, inducers, and inhibitors. Drug Metab Rev 2007;39:699-721
-
(2007)
Drug Metab Rev
, vol.39
, pp. 699-721
-
-
Liu, Y.T.1
Hao, H.P.2
Liu, C.X.3
-
57
-
-
3543042787
-
Genetic variability in CYP3A5 and its possible consequences
-
DOI 10.1517/phgs.5.3.243.29833
-
Xie HG, Wood AJ, Kim RB, et al. Genetic variability in CYP3A5 and its possible consequences. Pharmacogenomics 2004;5:243-72 (Pubitemid 38499965)
-
(2004)
Pharmacogenomics
, vol.5
, Issue.3
, pp. 243-272
-
-
Xie, H.-G.1
Wood, A.J.J.2
Kim, R.B.3
Stein, C.M.4
Wilkinson, G.R.5
-
58
-
-
33747098535
-
CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population
-
DOI 10.1097/01.fpc.0000230411.89973.1b, PII 0121301120060900000003
-
Mirghani RA, Sayi J, Aklillu E, et al. CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population. Pharmacogenet Genomics 2006;16:637-45 (Pubitemid 44223075)
-
(2006)
Pharmacogenetics and Genomics
, vol.16
, Issue.9
, pp. 637-645
-
-
Mirghani, R.A.1
Sayi, J.2
Aklillu, E.3
Allqvist, A.4
Jande, M.5
Wennerholm, A.6
Eriksen, J.7
Herben, V.M.M.8
Jones, B.C.9
Gustafsson, L.L.10
Bertilsson, L.11
-
60
-
-
40549112692
-
CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients
-
DOI 10.1097/FPC.0b013e3282f75f88, PII 0121301120080400000007
-
Hesselink DA, van Schaik RH, van Agteren M, et al. CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients. Pharmacogenet Genomics 2008;18:339-48 (Pubitemid 351367527)
-
(2008)
Pharmacogenetics and Genomics
, vol.18
, Issue.4
, pp. 339-348
-
-
Hesselink, D.A.1
Van Schaik, R.H.N.2
Van Agteren, M.3
De Fijter, J.W.4
Hartmann, A.5
Zeier, M.6
Budde, K.7
Kuypers, D.R.J.8
Pisarski, P.9
Meur, Y.L.10
Mamelok, R.D.11
Van Gelder, T.12
-
61
-
-
80054924410
-
A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients
-
Elens L, Bouamar R, Hesselink DA, et al. A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients. Clin Chem 2011;57(11):1574-83
-
(2011)
Clin Chem
, vol.57
, Issue.11
, pp. 1574-83
-
-
Elens, L.1
Bouamar, R.2
Hesselink, D.A.3
-
62
-
-
13544267712
-
Cytochrome P450 3A polymorphisms and immunosuppressive drugs
-
DOI 10.1517/14622416.6.1.37
-
Thervet E, Legendre C, Beaune P, et al. Cytochrome P450 3A polymorphisms and immunosuppressive drugs. Pharmacogenomics 2005;6:37-47 (Pubitemid 40220669)
-
(2005)
Pharmacogenomics
, vol.6
, Issue.1
, pp. 37-47
-
-
Thervet, E.1
Legendre, C.2
Beaune, P.3
Anglicheau, D.4
-
63
-
-
79960633918
-
Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
-
Wang D, Guo Y, Wrighton SA, et al. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. Pharmacogenomics J 2011;11:274-86
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 274-86
-
-
Wang, D.1
Guo, Y.2
Wrighton, S.A.3
-
64
-
-
8844271778
-
CYP3A variation and the evolution of salt-sensitivity variants
-
DOI 10.1086/426406
-
Thompson EE, Kuttab-Boulos H, Witonsky D, et al. CYP3A variation and the evolution of salt-sensitivity variants. Am J Hum Genet 2004;75:1059-69 (Pubitemid 39534403)
-
(2004)
American Journal of Human Genetics
, vol.75
, Issue.6
, pp. 1059-1069
-
-
Thompson, E.E.1
Kuttab-Boulos, H.2
Witonsky, D.3
Yang, L.4
Roe, B.A.5
Di Rienzo, A.6
-
65
-
-
40049103597
-
4beta-Hydroxycholesterol is a new endogenous CYP3A marker: Relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians
-
DOI 10.1097/FPC.0b013e3282f50ee9, PII 0121301120080300000004
-
Diczfalusy U, Miura J, Roh HK, et al. 4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3- hydroxylation and sex in Koreans, Swedes and Tanzanians. Pharmacogenet Genomics 2008;18:201-8 (Pubitemid 351323234)
-
(2008)
Pharmacogenetics and Genomics
, vol.18
, Issue.3
, pp. 201-208
-
-
Diczfalusy, U.1
Miura, J.2
Roh, H.-K.3
Mirghani, R.A.4
Sayi, J.5
Larsson, H.6
Bodin, K.G.7
Allqvist, A.8
Jande, M.9
Kim, J.-W.10
Aklillu, E.11
Gustafsson, L.L.12
Bertilsson, L.13
-
67
-
-
0032698297
-
Identification and characterisation of novel polymorphisms in the CYP2A locus: Implications for nicotine metabolism
-
DOI 10.1016/S0014-5793(99)01364-2, PII S0014579399013642
-
Oscarson M, McLellan RA, Gullsten H, et al. Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism. FEBS Lett 1999;460:321-7 (Pubitemid 29495962)
-
(1999)
FEBS Letters
, vol.460
, Issue.2
, pp. 321-327
-
-
Oscarson, M.1
McLellan, R.A.2
Gullsten, H.3
Agundez, J.A.G.4
Benitez, J.5
Rautio, A.6
Raunio, H.7
Pelkonen, O.8
Ingelman-Sundberg, M.9
-
68
-
-
0037291512
-
Nicotine metabolism, human drug metabolism polymorphisms, and smoking behaviour
-
DOI 10.1016/S0300-483X(02)00513-9, PII S0300483X02005139
-
Tricker AR. Nicotine metabolism, human drug metabolism polymorphisms, and smoking behaviour. Toxicology 2003;183:151-73 (Pubitemid 36005395)
-
(2003)
Toxicology
, vol.183
, Issue.1-3
, pp. 151-173
-
-
Tricker, A.R.1
-
69
-
-
42949141477
-
Novel arid established CYP2A6 alleles impair in vivo nicotine metabolism in a population of black African descent
-
DOI 10.1002/humu.20698
-
Mwenifumbo JC, Al Koudsi N, Ho MK, et al. Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent. Hum Mutat 2008;29:679-88 (Pubitemid 351614592)
-
(2008)
Human Mutation
, vol.29
, Issue.5
, pp. 679-688
-
-
Mwenifumbo, J.C.1
Al Koudsi, N.2
Man, K.H.3
Zhou, Q.4
Hoffmann, E.B.5
Sellers, E.M.6
Tyndale, R.F.7
-
70
-
-
77949615790
-
New CYP2A6 gene deletion and conversion variants in a population of Black African descent
-
Mwenifumbo JC, Zhou Q, Benowitz NL, et al. New CYP2A6 gene deletion and conversion variants in a population of Black African descent. Pharmacogenomics 2010;11:189-98
-
(2010)
Pharmacogenomics
, vol.11
, pp. 189-98
-
-
Mwenifumbo, J.C.1
Zhou, Q.2
Benowitz, N.L.3
-
71
-
-
33744968881
-
Adolescent nicotine metabolism: Ethnoracial differences among dependent smokers
-
Moolchan ET, Franken FH, Jaszyna-Gasior M. Adolescent nicotine metabolism: ethnoracial differences among dependent smokers. Ethn Dis 2006;16:239-43 (Pubitemid 46959274)
-
(2006)
Ethnicity and Disease
, vol.16
, Issue.1
, pp. 239-243
-
-
Moolchan, E.T.1
Franken, F.H.2
Jaszyna-Gasior, M.3
-
72
-
-
0036444114
-
Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6
-
Nakajima M, Kuroiwa Y, Yokoi T. Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6. Drug Metab Rev 2002;34:865-77
-
(2002)
Drug Metab Rev
, vol.34
, pp. 865-77
-
-
Nakajima, M.1
Kuroiwa, Y.2
Yokoi, T.3
-
73
-
-
4644255903
-
Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians
-
DOI 10.1097/00008571-200409000-00006
-
Schoedel KA, Hoffmann EB, Rao Y, et al. Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians. Pharmacogenetics 2004;14:615-26 (Pubitemid 39281816)
-
(2004)
Pharmacogenetics
, vol.14
, Issue.9
, pp. 615-626
-
-
Schoedel, K.A.1
Hoffmann, E.B.2
Rao, Y.3
Sellers, E.M.4
Tyndale, R.F.5
-
74
-
-
33646062273
-
Specific human CYP 450 isoform metabolism of a pentachlorobiphenyl (PCB-IUPAC# 101)
-
McGraw JE Sr, Waller DP. Specific human CYP 450 isoform metabolism of a pentachlorobiphenyl (PCB-IUPAC# 101). Biochem Biophys Res Commun 2006;344:129-33
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 129-33
-
-
McGraw, Sr.J.E.1
Waller, D.P.2
-
75
-
-
57149142497
-
The role of African American ethnicity and metabolism in sentinel polychlorinated biphenyl congener serum levels
-
McGraw JE, Waller DP. The role of African American ethnicity and metabolism in sentinel polychlorinated biphenyl congener serum levels. Environ Toxicol Pharmacol 2009;27:54-61
-
(2009)
Environ Toxicol Pharmacol
, vol.27
, pp. 54-61
-
-
McGraw, J.E.1
Waller, D.P.2
-
76
-
-
52449133102
-
CYP2B6: New insights into a historically overlooked cytochrome P450 isozyme
-
Wang H, Tompkins LM. CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Curr Drug Metab 2008;9:598-610
-
(2008)
Curr Drug Metab
, vol.9
, pp. 598-610
-
-
Wang, H.1
Tompkins, L.M.2
-
77
-
-
38449095701
-
Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism
-
DOI 10.1097/01.fpc.0000220560.59972.33, PII 0121301120071200000001
-
Ring HZ, Valdes AM, Nishita DM, et al. Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism. Pharmacogenet Genomics 2007;17:1007-15 (Pubitemid 351339485)
-
(2007)
Pharmacogenetics and Genomics
, vol.17
, Issue.12
, pp. 1007-1015
-
-
Ring, H.Z.1
Valdes, A.M.2
Nishita, D.M.3
Prasad, S.4
Jacob III, P.5
Tyndale, R.F.6
Swan, G.E.7
Benowitz, N.L.8
-
78
-
-
41149132905
-
Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in liver
-
DOI 10.1124/jpet.107.133306
-
Hofmann MH, Blievernicht JK, Klein K, et al. Aberrant splicing caused by single nucleotide polymorphism c.516G > T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in liver. J Pharmacol Exp Ther 2008;325:284-92 (Pubitemid 351439175)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.325
, Issue.1
, pp. 284-292
-
-
Hofmann, M.H.1
Blievernicht, J.K.2
Klein, K.3
Saussele, T.4
Schaeffeler, E.5
Schwab, M.6
Zanger, U.M.7
-
79
-
-
33747789083
-
Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese
-
DOI 10.1016/j.ejps.2006.04.004, PII S0928098706001084
-
Guan S, Huang M, Chan E, et al. Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese. Eur J Pharm Sci 2006;29:14-21 (Pubitemid 44279393)
-
(2006)
European Journal of Pharmaceutical Sciences
, vol.29
, Issue.1
, pp. 14-21
-
-
Guan, S.1
Huang, M.2
Chan, E.3
Chen, X.4
Duan, W.5
Zhou, S.-F.6
-
80
-
-
33750592308
-
Intraand inter-ethnic differences in the allele frequencies of cytochrome P450 2B6 gene in Chinese
-
Guan S, Huang M, Li X, et al. Intraand inter-ethnic differences in the allele frequencies of cytochrome P450 2B6 gene in Chinese. Pharm Res 2006;23:1983-90
-
(2006)
Pharm Res
, vol.23
, pp. 1983-90
-
-
Guan, S.1
Huang, M.2
Li, X.3
-
81
-
-
67649177436
-
Plasma efavirenz concentrations and the association with CYP2B6-516G > T polymorphism in HIV-infected Thai children
-
Puthanakit T, Tanpaiboon P, Aurpibul L, et al. Plasma efavirenz concentrations and the association with CYP2B6-516G > T polymorphism in HIV-infected Thai children. Antivir Ther 2009;14:315-20
-
(2009)
Antivir Ther
, vol.14
, pp. 315-20
-
-
Puthanakit, T.1
Tanpaiboon, P.2
Aurpibul, L.3
-
82
-
-
62549089177
-
Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine
-
Ramachandran G, Ramesh K, Hemanth Kumar AK, et al. Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine. J Antimicrob Chemother 2009;63:841-3
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 841-3
-
-
Ramachandran, G.1
Ramesh, K.2
Hemanth Kumar, A.K.3
-
83
-
-
62549099045
-
Pharmacogenomics of CYP2A6 CYP2B6 CYP2C19 CYP2D6 CYP3A4 CYP3A5 and MDR1 in Vietnam
-
Veiga MI, Asimus S, Ferreira PE, et al. Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam. Eur J Clin Pharmacol 2009;65:355-63
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 355-63
-
-
Veiga, M.I.1
Asimus, S.2
Ferreira, P.E.3
-
84
-
-
34248998418
-
Genetic variability of CYP2B6 polymorphisms in four southern Chinese populations
-
Xu BY, Guo LP, Lee SS, et al. Genetic variability of CYP2B6 polymorphisms in four southern Chinese populations. World J Gastroenterol 2007;13:2100-3
-
(2007)
World J Gastroenterol
, vol.13
, pp. 2100-3
-
-
Xu, B.Y.1
Guo, L.P.2
Lee, S.S.3
-
85
-
-
33750454425
-
Pyrosequencing-based screening for genetic polymorphisms in cytochrome P450 2B6 of potential clinical relevance
-
DOI 10.2217/14622416.7.7.995
-
Rohrbacher M, Kirchhof A, Geisslinger G, et al. Pyrosequencing-based screening for genetic polymorphisms in cytochrome P450 2B6 of potential clinical relevance. Pharmacogenomics 2006;7:995-1002 (Pubitemid 44644779)
-
(2006)
Pharmacogenomics
, vol.7
, Issue.7
, pp. 995-1002
-
-
Rohrbacher, M.1
Kirchhof, A.2
Geisslinger, G.3
Lotsch, J.4
-
86
-
-
73349108767
-
Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2
-
Zhou SF, Yang LP, Zhou ZW, et al. Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2. Aaps J 2009;11:481-94
-
(2009)
Aaps J
, vol.11
, pp. 481-94
-
-
Zhou, S.F.1
Yang, L.P.2
Zhou, Z.W.3
-
87
-
-
41549109042
-
Cytochrome P450 enzyme polymorphism frequency in indigenous and native American populations: A systematic review
-
DOI 10.1159/000113876
-
Jaja C, Burke W, Thummel K, et al. Cytochrome p450 enzyme polymorphism frequency in indigenous and native American populations: a systematic review. Community Genet 2008;11:141-9 (Pubitemid 351465617)
-
(2008)
Community Genetics
, vol.11
, Issue.3
, pp. 141-149
-
-
Jaja, C.1
Burke, W.2
Thummel, K.3
Edwards, K.4
Veenstra, D.L.5
-
88
-
-
0036223831
-
Summary of information on human CYP enzymes: Human P450 metabolism data
-
DOI 10.1081/DMR-120001392
-
Rendic S. Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev 2002;34(1-2):83-448 (Pubitemid 34311090)
-
(2002)
Drug Metabolism Reviews
, vol.34
, Issue.1-2
, pp. 83-448
-
-
Rendic, S.1
|