Neuroprotective effect of TAT-14-3-3ε fusion protein against cerebral ischemia/reperfusion injury in rats

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Zhu, Yuanjun ^a   Bu, Qixin ^a   Liu, Xiaoyan ^a   Hu, Wenhui ^b   Wang, Yinye ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; CASPASE 3; HYBRID PROTEIN; PROTEIN P62; TAT 14 3 3 EPSILON FUSION PROTEIN; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT; PROTEIN 14 3 3; TRANSACTIVATOR PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFICACY; ENZYME INHIBITION; IN VIVO STUDY; MALE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; REPERFUSION INJURY; SYSTEMIC THERAPY; UPREGULATION; ANIMAL; BRAIN CORTEX; DRUG EFFECTS; DRUG SCREENING; INFARCTION, MIDDLE CEREBRAL ARTERY; NERVE CELL; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULARIZATION;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; CEREBRAL CORTEX; DRUG EVALUATION, PRECLINICAL; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEURONS; NEUROPROTECTIVE AGENTS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; REPERFUSION INJURY; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84899866766     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093334     Document Type: Article

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