Tramiprosate protects neurons against ischemic stroke by disrupting the interaction between PSD95 and nNOS

Neuropharmacology

Volumn 83, Issue , 2014, Pages 107-117

  Wu, Shuangchan ^a   Yue, Yuan ^a   Tian, Hui ^a   Tao, Li ^a   Wang, Yuting ^a   Xiang, Jin ^a   Wang, Shi ^b   Ding, Hong ^a  

^a WUHAN UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Functional recovery; Ischemic stroke; PSD95 nNOS; Tramiprosate

Indexed keywords

DIZOCILPINE; HOMOTAURINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE SYNTHASE; POSTSYNAPTIC DENSITY PROTEIN 95; DLGH4 PROTEIN, RAT; MEMBRANE PROTEIN; NEURONAL NITRIC OXIDE SYNTHASE; NEUROPROTECTIVE AGENT; SIGNAL PEPTIDE; TAURINE;

ADHESIVE REMOVAL SOMATOSENSORY TEST; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; DOSE RESPONSE; EMBRYO; EXPERIMENTAL TEST; FOOT FAULT TEST; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; NEUROLOGICAL SEVERITY SCORE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; SCORING SYSTEM; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; DRUG EFFECTS; METABOLISM; NERVE CELL; PC12 CELL LINE; SPRAGUE DAWLEY RAT; STROKE;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE I; PC12 CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; STROKE; TAURINE;

EID: 84899852152     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.04.010     Document Type: Article

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