Short therapeutic window for MK-801 in transient focal cerebral ischemia in normotensive rats

Journal of Cerebral Blood Flow and Metabolism

Volumn 16, Issue 1, 1996, Pages 107-113

  Margaill, I ^a   Parmentier, S ^a   Callebert, J ^a   Allix, M ^a   Boulu, R G ^a   Plotkine, M ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Glutamate; Microdialysis; MK 801; Transient focal ischemia

Indexed keywords

DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN PROTECTION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DRUG MECHANISM; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030033031     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199601000-00013     Document Type: Article

References (32)

1. Buchan AM, Xue D, Slivka A (1992) A new model of temporary focal neocortical ischemia in the rat. Stroke 23:273-279
2. Buisson A, Margaill I, Callebert J, Plotkine M, Boulu RG (1993) Mechanisms involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia, J Neurochem 61:690-696
3. Butcher SP, Bullock R, Graham DI, McCulloch J (1990) Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke 21:1727-1733
4. Crockard HA, Symon L, Brantson NM, Juhasz J, Wahid A (1976) Measurements of oxygen tension in the cerebral cortex of baboons. J Neurol Sci 27:17-28
5. Dawson DA, Graham DI, McCulloch J, Macrae IM (1994) Antiischaemic efficacy of a nitric oxide synthase inhibitor and a N-methyl-D-aspartate receptor antagonist in models of transient and permanent focal cerebral ischaemia. Br J Pharmacol 113:247-253
6. Dezsi L, Greenberg JH, Sladky J, Araki N, Hamar J, Reivich M (1994) Prolonged effects of MK-801 in the cat during focal cerebral ischemia and recovery: survival, EEG activity and histopathology. J Neurol Sci 121:110-120
7. Fox G, Gallacher D, Shevde S, Loftus J, Swayne G (1993) Anatomic variation of the middle cerebral artery in the Sprague-Dawley rat. Stroke 24:2087-2093
8. Golanov EV, Reis DJ (1995) Contribution of cerebral edema to the neuronal salvage elicited by stimulation of cerebellar fastigial nucleus after occlusion of the middle cerebral artery in rat. J Cereb Blood Flow Metab 15:172-173
9. Goto Y, Kassell NF, Hiramatsu K-I, Soleau SW, Lee KS (1993) Effects of intraischemic hypothermia on cerebral damage in a model of reversible focal ischemia. Neurosurgery 32:980-985
10. Hatfield RH, Gill R, Brazell C (1992) The dose-response relationship and therapeutic window for dizocilpine (MK-801) in a rat focal ischaemia model. Eur J Pharmacol 216:1-7
11. He YY, Hsu CY, Ezrin AM, Miller MS (1993) Polyethylene glycol-conjugated Superoxide dismutase in focal cerebral ischemia-reperfusion. Am J Physiol 265:H252-H256
12. Hillered L, Hallström A, Segersvärd S, Persson L, Ungerstedt U (1989) Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis. J Cereb Blood Flow Metab 9:607-616
13. Hiramatsu K, Kassel NF, Goto Y, Soleau S, Lee KS (1993) A reproducible model of reversible, focal, neocortical ischemia in Sprague-Dawley rat. Acta Neurochir (Wien) 120:66-71
14. Hsu CY (1993) Criteria for valid preclinical trials using animal stroke models. Stroke 24:633-636
15. Lin TN, He YY, Wu G, Khan M, Hsu CY (1993) Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke 24:117-121
16. Lindroth P, Mopper K (1979) High performance liquid Chromatographic determination of subpicomole amount of amino acids by precolumn fluorescence derivatisation with o-phthaldialdehyde. Anal Chem 51:1667-1674
17. Longa EZ, Weinstein PR, Carlson S, Curnmins R (1989) Reversible middle cerebral artery occlusion without craniotomy in rats. Stroke 20:84-91
18. Macrae IM (1992) New models of focal cerebral ischaemia. Br J Clin Pharmacol 34:302-308
19. Memezawa H, Minamisawa H, Smith ML, Siesjö BK (1992) Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat. Exp Brain Res 89:67-78
20. Mohr JP, Gautier JC, Hier D, Stein RW (1986) Middle cerebral artery. In: Stroke, Vol 1: Pathophysiology, Diagnosis and Management (Barnett HJM, Stein BM, Mohr JP, Yatsu FM, eds), New York, Churchill Livingstone, pp 377-450
21. Muszynski CA, Robertson CS, Goodman JC, Henley CM (1993) DFMO reduces cortical infarct volume after middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 13: 1033-1037
22. Nagasawa H, Kogure K (1989) Correlation between cerebral blood flow and histologie changes in a new rat model of middle cerebral artery occlusion. Stroke 20:1037-1043
23. Park CK, Nehls DG, Graham DI, Teasdale GM, McCulloch J (1988) The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat. Ann Neurol 24:543-551
24. Paxinos G, Watson C (1986) The Rat Brain Stereotaxic Coordinates. 2nd ed. Sydney, Academic Press
25. Robinson TE, Whishaw IQ (1988) Normalization of extracellular dopamine in the striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats. Brain Res 450:209-224
26. Takagi K, Ginsberg MD, Globus MYT, Martinez E, Busto R (1994) Effect of hyperthermia on glutamate release in ischemic penumbra after middle cerebral artery occlusion in rats. Am J Physiol 266:H1770-H1776
27. Uchiyama-Tsuyuki Y, Araki H, Yae T, Otomo S (1994) Changes in the extracellular concentrations of amino acids in the rat striatum during transient focal cerebral ischemia. J Neurochem 62:1074-1078
28. Wong EHF, Kemp JA, Priesley T, Knight AR, Woodruff GN, Iversen LL (1986) The anticonvulsivant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci USA 83:7104-7108
29. Xue D, Huang Z-G, Barnes K, Lesiuk HJ, Smith KE, Buchan AM (1994) Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction. J Cereb Blood Flow Metab 14:251-261
30. Yamaguchi T, Minematsu K, Choki J (1987) Arterial embolism. In: Cerebral Blood Flow-Physiologic and Clinical Aspects (Wood JH, ed), New York, McGraw-Hill, pp 503-517
31. Yang G, Chan PH, Chen SF, Babuna OA, Simon RP, Weinstein PR (1994) Reduction of vasogenic edema and infarction by MK-801 in rats after temporary focal cerebral ischemia. Neurosurgery 34:339-345
32. Yip PK, He YY, Hsu CY, Garg N, Marangos P, Hogan EL (1991) Effect of plasma glucose on infarct size in a focal cerebral ischemia-reperfusion. Neurology 41:899-905