Enhanced survival and function of islet-like clusters differentiated from adipose stem cells on a three-dimensional natural polymeric scaffold: An in vitro study

Tissue Engineering - Part A

Volumn 20, Issue 9-10, 2014, Pages 1508-1522

  Aloysious, Neena ^a   Nair, Prabha D ^a  

^a SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; STEM CELLS; THREE DIMENSIONAL;

ADIPOSE STEM CELLS; BIODEGRADABLE SCAFFOLD; EXTRACELLULAR ENVIRONMENTS; EXTRACELLULAR MATRICES; NEW ZEALAND WHITE RABBIT; PANCREATIC BETA CELLS; POLYMERIC SCAFFOLD; SIGNALING INTERACTIONS;

SCAFFOLDS (BIOLOGY);

DEXTRAN; GELATIN; GLUCAGON; INSULIN; SOMATOSTATIN; BIOPOLYMER;

ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; IN VITRO STUDY; INSULIN RELEASE; MORPHOLOGY; NEW ZEALAND WHITE (RABBIT); NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; SUBCUTANEOUS FAT; ADIPOCYTE; ANIMAL; ARTIFICIAL PANCREAS; BIODEGRADABLE IMPLANT; CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; GROWTH, DEVELOPMENT AND AGING; PANCREAS ISLET; PHYSIOLOGY; PROSTHESIS; RABBIT; STEM CELL; TISSUE SCAFFOLD;

ABSORBABLE IMPLANTS; ADIPOCYTES; ANIMALS; BIOPOLYMERS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; ISLETS OF LANGERHANS; PANCREAS, ARTIFICIAL; PROSTHESIS DESIGN; RABBITS; STEM CELLS; TISSUE SCAFFOLDS;

EID: 84899814196     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0615     Document Type: Article

References (49)

1. Shapiro, A.M., Lakey, J.R., Ryan, E.A., Korbutt, G.S., Toth, E., Warnock, G.L., Kneteman, N.M., and Rajotte, R.V. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343, 230, 2000.
2. Ryan, E.A., Lakey, J.R., Rajotte, R.V., Korbutt, G.S., Kin, T., Imes, S., Rabinovitch, A., Elliott, J.F., Bigam, D., Kneteman, N.M., Warnock, G.L., Larsen, I., and Shapiro, A.M. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 50, 710, 2001.
3. Segev, H., Fishman, B., Ziskind, A., Shulman, M., and Itskovitz-Eldor, J. Differentiation of human embryonic stem cells into insulin-producing clusters. Stem Cells 22, 265, 2004.
4. Phadnis, S.M., Joglekar, M.V., Dalvi, M.P., Muthyala, S., Nair, P.D., Ghaskadbi, S.M., Bhonde, R.R., and Hardikar, A.A. Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo. Cytotherapy 13, 1, 2010.
5. Zulewski, H., Abraham, E.J., Gerlach, M.J., Daniel, P.B., Moritz, W., Muller, B., Vallejo, M., Thomas, M.K., and Habener, J.F. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50, 521, 2001.
6. Chao, K.C., Chao, K.F., Fu, Y.S., and Liu, S.H. Islet-like clusters derived from mesenchymal stem cells in Wharton's jelly of the human umbilical cord for transplantation to control type 1 diabetes. PLoS One 1, e1451, 2008.
7. Yang, L., Li, S., Hatch, H., Ahrens, K., Cornelius, J.G., Petersen, B.E., and Peck, A.B. In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone producing cells. Proc Natl Acad Sci USA 99, 8078, 2002.
8. Timper, K., Seboek, D., Eberhardt, M., Linscheid, P., Christ-Crain, M., Keller, U., Muller, B., and Zulewski, H. Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells. Biochem Biophys Res Commun 341, 1135, 2006.
9. Govindasamy, V., Ronald, V.S., Abdullah, A.N., Nathan, K.R., Aziz, Z.A., Abdullah, M., Musa, S., Kasim N.H., and Bhonde, R.R. Differentiation of dental pulp stem cells into islet-like aggregates. J Dent Res 90, 646, 2011.
10. Chandra, V., Swetha, G., Muthyala, S., Jaiswal, A.K., Bellare, J.R., Nair, P.D., and Bhonde, R.R. Islet-like cell aggregates generated from human adipose tissue derived stem cells ameliorate experimental diabetes in mice. PLoS One 6, e20615, 2011.
11. Bosco, D., Meda P., Halban, P.A., and Rouiller, D.G. Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro:role of alpha6beta1 integrin. Diabetes 49, 233, 2000.
12. Stendahl, J.C., Kaufman, D.B., and Stupp, S.I. Extracellular matrix in pancreatic islets: relevance to scaffold design and transplantation. Cell Transplant 18, 1, 2009.
13. Kin, T., O'Neil, J.J., Pawlick, R., Korbutt, G.S., Shapiro, A.M., and Lakey, J.R. The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment. Artif Organs 32, 990, 2008.
14. Navarro-Alvarez, N., Rivas-Carrilo, J.D., Soto-Gutierrez, A., Yuasa, T., Okitsu, T., Noguchi, H., Matsumoto S., Takei, J., Tanaka, N., and Kobayashi, N. Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function. Cell Transplant 17, 111, 2008.
15. Chun, S., Huang, Y., Xie, W.J., Hou, Y., Huang, R.P., Song, Y.M., Liu, X.M., Zheng, W., Shi, Y., and Song, C.F. Adhesive growth of pancreatic islet cells on a polyglycolic acid fibrous scaffold. Transplant Proc 40, 1658, 2008.
16. Cheng, J.Y., Raghunath, M., Whitelock, J., and Poole-Warren, L. Matrix components and scaffolds for sustained islet function. Tissue Eng Part B Rev 17, 235, 2011.
17. Nowakowska, M., Zapotoczny, S., Sterzel, M., and Kot, E. Novel water-soluble hotosensitizers from dextrans. Biomacromolecules 5, 1009, 2004.
18. Lee, S.B., Kim, Y.H., Chong, M.S., Hong, S.H., and Lee, Y.M. Study of gelatin-containing artificial skin: fabrication of gelatin scaffolds using a salt-leaching method. Biomaterials 26, 1961, 2005.
19. Liu, H., Yao, F., Zhou, Y., Yao, K., Mei, D., Cui, L., and Cao, Y. Porous poly (DL-lactic acid) modified chitosangelatin scaffolds for tissue engineering. J Biomater Appl 19, 303, 2005.
20. Draye, J.P., Delaey, B., Voorde, A.V., Bulcke, A.V., Reu, B.D., and Schacht, E. In vitro and in vivo biocompatibility of dextran dialdehyde cross-linked gelatin hydrogel films. Biomaterials 19, 1677, 1998.
21. Draye, J.P., Delaey, B., Voorde, A.V., Bulcke, A.V., Bogdanov, B., and Schacht, E. In vitro release characteristics of bioactive molecules from dextran dialdehyde cross-linked gelatin hydrogel films. Biomaterials 19, 99, 1998.
22. Lumelsky, N., Blondel, O., Laeng, P., Velasco, I., Ravin, R., and McKay, R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292, 1389, 2001.
23. Hori, Y., Rulifson, I.C., Tsai, B.C., Heit, J.J., Cahoy, J.D., and Kim, S.K. Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells. Proc Natl Acad Sci USA 99, 16105, 2002.
24. Hansson, M., Tonning, A., Frandsen, U., Petri, A., Rajagopal, J., Englund, M.C., Heller, R.S., Hakansson, J., Fleckner, J., Sko, H.N., Melton, D., Semb, H., and Serup, P. Artifactual insulin release from differentiated embryonic stem cells. Diabetes 53, 2603, 2004.
25. Yu, S., Li, C., Xin-guo, H., Wei-kai, H., Jian-jun, D., Lei, S., Kuan-xiao, T., Bin, W., Jun, S., Hui, L., and Ke-xin, W. Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitro. Chin Med J 120, 771, 2007.
26. Zuk, P.A., Zhu, M., Ashjian, P., De Ugarte, D.A., Huang, J.I., Mizuno, H., Alfonso, Z.C., Fraser, J.K., Benhaim, P., and Hedrick, M.H. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 13, 4279, 2002.
27. Romanov, Y.A., Darevskaya, A.N., Merzlikina, N.V., and Buravkova, L.B. Mesenchymal stem cells from human bone marrow and adipose tissue: isolation, characterization, and differentiation potentialities. Bull Exp Biol Med 140, 138, 2005.
28. Kern, S., Eichler, A.H., Stoeve, A.J., Uter, B.H., and Bieback, A.K. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem cells 24, 1294, 2006.
29. Gimble, J.M., and Guilak, F. Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. Cytotherapy 5, 362, 2003.
30. Balakrishnan, B., Mohanty, M., Umashankar, P.R., and Jayakrishnan, A. Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin. Biomaterials 26, 6335, 2005.
31. Iscove, N.N., and Sieber, F. Erythroid progenitors in mouse bone marrow detected by macroscopic colony formation in culture. Exp Hematol 3, 32, 1975.
32. Maghasi, A.T., Schlueter, K.T., Halsall, H.B., Heineman, W.R., and Rodriguez Rilo, H.L. Development and characterization of simulant pancreatic islets. Anal Biochem 314, 38, 2003.
33. Delle, H., Saito, M.H., Yoshimoto, P.M., and Noronha, I.L. The use of lodixanol for the purification of rat pancreatic islets. Transplant Proc 39, 467, 2007.
34. Beattie, G.M., Montgomery, A.M., Lopez, A.D., Hao, E., Perez, B., Just, M.L., Lakey, J.R., Hart, M.E., and Hayek, A. A novel approach to increase human islet cell mass while preserving cell function. Diabetes 51, 3435, 2002.
35. Muthyala, S., Bhonde R.R., and Nair, P.D. Cytocompatibility studies of mouse pancreatic islets on gelatin-PVP semi IPN scaffolds in vitro. Potential implication towards pancreatic tissue engineering. Islets 2, 357, 2010.
36. Weber, L.M., Hayda, K.N., and Anseth, K.S. Cell-matrix interactions improve b-cell survival and insulin secretion in three-dimensional culture. Tissue Eng Part A 14, 1959, 2008.
37. Hammar, E., Parnaud, G., Bosco, D., Perriraz, N., Maedler, K., Donath, M., Rouiller, D.G., and Halban, P.A. Extracellular matrix protects pancreatic cells against apoptosis .role of short-and long-term signaling pathways. Diabetes 53, 2034, 2004.
38. Lehmann, R., Zuellig, R.A., Kugelmeier, P., Baenninger, P.B., Moritz, W., Perren, A., Clavien, P.A., Weber, M., and Spinas, G.A. Superiority of small islets in human islet transplantation. Diabetes 56, 594, 2007.
39. Norgaard, G.A., Jensen, J.N., and Jensen, J. FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development. Dev Biol 264, 323, 2003.
40. Suarez-Pinzon, W.L., Lakey, J.R., Brand, S.J., and Rabinovitch, A. Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet-cells from pancreatic duct cells and an increase in functional-cell mass. J Clin Endocrinol Metab 90, 3401, 2005.
41. Miettinen, P., Ormio, P., Hakonen, E., Banerjee, M., and Otonkoski, T. EGF receptor in pancreatic b-cell mass regulation. Biochem Soc Trans 36, 280, 2008.
42. Neshati, Z., Matin, M.M., Bahrami, A.R., and Moghimi, A. Differentiation of mesenchymal stem cells to insulinproducing cells and their impact on type 1 diabetic rats. J Physiol Biochem 66, 181, 2010.
43. Kolb, H., and Burkart, V. Nicotinamide in type 1 diabetes. Mechanism of action revisited. Diabetes Care 22, B16, 1999.
44. Demeterco, C., Beattie, G.M., Dib, S.A., Lopez, A.D., and Hayek, A. A role for activin A and betacellulin in human fetal pancreatic cell differentiation and growth. J Clin Endocrinol Metab 85, 3892, 2000.
45. Wang, R.L., and Rosenberg, L.J. Maintainenece of beta cell function and survival following islet isolation requires reestablishent of the islet-matrix relationship. Endocrinology 163, 181, 1999.
46. Daoud, J., Petropavlovskaia, M., Rosenberg, L., and Tabrizian, M. The effect of extracellular matrix components on the preservation of human islet function in vitro. Biomaterials 31, 1676, 2010.
47. Kawazoe, N., Lin, X., Tateishi, T., and Chen, G.J. Threedimensional cultures of rat pancreatic RIN-5F cells in porous PLGA-collagen hybrid scaffolds. Bioact Compat Polym 24, 25, 2009.
48. Gao, S.Y., Wong, J.C., Lees, J.G., Best, M.B., Wang, R., George, P.A., Cooper-White, J.J., and Tuch, B.E. The generation of definitive endoderm from human embryonic stem cells on 3D biodegradable poly(lactic-co-glycolic Acid) scaffolds and its comparison to those generated on 2D monolayer cultures. Open Stem Cell J 3, 23, 2011.
49. Mao, G., Chen, G., Bai, H., Song, T., and Wang, Y. The reversal of hyperglycaemia in diabetic mice using PLGA scaffolds seeded with islet-like cells derived from human embryonic stem cells. Biomaterials 30, 1706, 2009.