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Volumn 95, Issue 5, 2014, Pages 743-753

DNA demethylating agent 5-azacytidine inhibits myeloid-derived suppressor cells induced by tumor growth and cyclophosphamide treatment

Author keywords

Arginase 1; Immunosuppression; Microenvironment

Indexed keywords

AZACITIDINE; CYCLOPHOSPHAMIDE; PROTEIN; PROTEIN ARG 1; UNCLASSIFIED DRUG; VASCULOTROPIN; ANTINEOPLASTIC AGENT;

EID: 84899804950     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0813435     Document Type: Article
Times cited : (46)

References (44)
  • 2
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich, D. I., Nagaraj, S. (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9, 162-174.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 3
    • 84856760496 scopus 로고    scopus 로고
    • Tumor microenvironment and myeloidderived suppressor cells
    • Umansky, V., Sevko, A. (2012) Tumor microenvironment and myeloidderived suppressor cells. Cancer Microenvironment 61, 275-282.
    • (2012) Cancer Microenvironment , vol.61 , pp. 275-282
    • Umansky, V.1    Sevko, A.2
  • 4
    • 84879159574 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: Thick as thieves
    • Sevko, A., Umansky, V. (2013) Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: thick as thieves. J. Cancer 4, 3-11.
    • (2013) J. Cancer , vol.4 , pp. 3-11
    • Sevko, A.1    Umansky, V.2
  • 6
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn, J. I., Nagaraj, S., Collazo, M., Gabrilovich, D. I. (2008) Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 181, 5791-5802.
    • (2008) J. Immunol. , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 7
    • 0041850021 scopus 로고    scopus 로고
    • Inhibition of myeloid cell differentiation in cancer: The role of reactive oxygen species
    • Kusmartsev, S., Gabrilovich, D. I. (2003) Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species. J. Leukoc. Biol. 74, 186-196.
    • (2003) J. Leukoc. Biol. , vol.74 , pp. 186-196
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 8
    • 28044445899 scopus 로고    scopus 로고
    • Role of immature myeloid cells in mechanisms of immune evasion in cancer
    • Kusmartsev, S., Gabrilovich, D. I. (2006) Role of immature myeloid cells in mechanisms of immune evasion in cancer. Cancer Immunol. Immunother. 55, 237-245.
    • (2006) Cancer Immunol. Immunother. , vol.55 , pp. 237-245
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 9
    • 33846933459 scopus 로고    scopus 로고
    • L-Arginine availability regulates T-lymphocyte cell-cycle progression
    • Rodriguez, P. C., Quiceno, D. G., Ochoa, A. C. (2007) L-Arginine availability regulates T-lymphocyte cell-cycle progression. Blood 109, 1568-1573.
    • (2007) Blood , vol.109 , pp. 1568-1573
    • Rodriguez, P.C.1    Quiceno, D.G.2    Ochoa, A.C.3
  • 12
    • 0034551670 scopus 로고    scopus 로고
    • Identification of a CD11b+/Gr-1β/CD31β myeloid progenitor capable of activating or suppressing CD8+ T cells
    • Bronte, V., Apolloni, E., Cabrelle, A., Ronca, R., Serafini, P., Zamboni, P., Restifo, N. P., Zanovello, P. (2000) Identification of a CD11b+/Gr-1β/CD31β myeloid progenitor capable of activating or suppressing CD8+ T cells. Blood 96, 3838-3846.
    • (2000) Blood , vol.96 , pp. 3838-3846
    • Bronte, V.1    Apolloni, E.2    Cabrelle, A.3    Ronca, R.4    Serafini, P.5    Zamboni, P.6    Restifo, N.P.7    Zanovello, P.8
  • 14
    • 0343185921 scopus 로고    scopus 로고
    • Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+)CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: Implications for T-cell responses in immunosuppressed mice
    • Angulo, I., de las Heras, F. G., García-Bustos, J. F., Gargallo, D., Muñoz-Fernández, M. A., Fresno, M. (2000) Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+)CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: implications for T-cell responses in immunosuppressed mice. Blood 95, 212-220.
    • (2000) Blood , vol.95 , pp. 212-220
    • Angulo, I.1    de las Heras, F.G.2    García-Bustos, J.F.3    Gargallo, D.4    Muñoz-Fernández, M.A.5    Fresno, M.6
  • 15
    • 17544401819 scopus 로고    scopus 로고
    • Cyclophosphamide induces the development of early myeloid cells suppressing tumor cell growth by a nitric oxide-dependent mechanism
    • Peláez, B., Campillo, J. A., López-Asenjo, J. A., Subiza, J. L. (2001) Cyclophosphamide induces the development of early myeloid cells suppressing tumor cell growth by a nitric oxide-dependent mechanism. Immunology 166, 6608-6615.
    • (2001) Immunology , vol.166 , pp. 6608-6615
    • Peláez, B.1    Campillo, J.A.2    López-Asenjo, J.A.3    Subiza, J.L.4
  • 16
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
    • Diaz-Montero, C. M., Salem, M. L., Nishimura, M. I., Garrett-Mayer, E., Cole, D. J., Montero, A. J. (2009) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol. Immunother. 58, 49-59.
    • (2009) Cancer Immunol. Immunother. , vol.58 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3    Garrett-Mayer, E.4    Cole, D.J.5    Montero, A.J.6
  • 17
    • 84861231386 scopus 로고    scopus 로고
    • Cyclophosphamide-induced myeloid-derived suppressor cell population is immunosuppressive but not identical to myeloid-derived suppressor cells induced by growing TC-1 tumours
    • Mikyšková, R., Indrová, M., Polláková, V., Bieblová, J., Šímová, J., Reiniš, M. (2012) Cyclophosphamide-induced myeloid-derived suppressor cell population is immunosuppressive but not identical to myeloid-derived suppressor cells induced by growing TC-1 tumours. J. Immunotherapy 35, 376-384.
    • (2012) J. Immunotherapy , vol.35 , pp. 376-384
    • Mikyšková, R.1    Indrová, M.2    Polláková, V.3    Bieblová, J.4    Šímová, J.5    Reiniš, M.6
  • 18
    • 70350786392 scopus 로고    scopus 로고
    • Cyclophosphamide and cancer: Golden anniversary
    • Emadi, A., Jones, R. J., Brodsky, R. A. (2009) Cyclophosphamide and cancer: golden anniversary. Nat. Rev. Clin. Oncol. 611, 638-647.
    • (2009) Nat. Rev. Clin. Oncol. , vol.611 , pp. 638-647
    • Emadi, A.1    Jones, R.J.2    Brodsky, R.A.3
  • 19
    • 68849128500 scopus 로고    scopus 로고
    • Therapeutic targeting of myeloid-derived suppressor cells
    • Ugel, S., Delpozzo, F., Desantis, G. (2009) Therapeutic targeting of myeloid-derived suppressor cells. Curr. Opin. Pharmacol. 9, 470-481.
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 470-481
    • Ugel, S.1    Delpozzo, F.2    Desantis, G.3
  • 21
    • 77449149374 scopus 로고    scopus 로고
    • Multicenter phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia
    • Cashen, A. F., Schiller, G. J., O'Donnell, M. R., Dipersio, J. F. (2010) Multicenter phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia. J. Clin. Oncol. 28, 556-561.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 556-561
    • Cashen, A.F.1    Schiller, G.J.2    O'Donnell, M.R.3    Dipersio, J.F.4
  • 23
    • 33745599088 scopus 로고    scopus 로고
    • Epigenetic regulation of immune escape genes in cancer
    • Tomasi, T. B., Magner, W. J., Khan, A. N. (2006) Epigenetic regulation of immune escape genes in cancer. Cancer Immunol. Immunother. 55, 1159-1184.
    • (2006) Cancer Immunol. Immunother. , vol.55 , pp. 1159-1184
    • Tomasi, T.B.1    Magner, W.J.2    Khan, A.N.3
  • 24
    • 37849033441 scopus 로고    scopus 로고
    • Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours
    • Manning, J., Indrová, M., Lubyová B, Přibylová, H., Bieblová, J., Hejnar, J., Šímová, J., Jandlová, T., Bubeník, J., Reiniš, M. (2008) Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. Immunology 123, 218-227.
    • (2008) Immunology , vol.123 , pp. 218-227
    • Manning, J.1    Indrová, M.2    Lubyová, B.3    Přibylová, H.4    Bieblová, J.5    Hejnar, J.6    Šímová, J.7    Jandlová, T.8    Bubeník, J.9    Reiniš, M.10
  • 27
    • 78149422805 scopus 로고    scopus 로고
    • Immunotherapy of MHC class I-deficient tumors
    • Reiniš, M. (2010) Immunotherapy of MHC class I-deficient tumors. Future Oncol. 6, 1577-1589.
    • (2010) Future Oncol. , vol.6 , pp. 1577-1589
    • Reiniš, M.1
  • 30
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki, E., Kapoor, V., Jassar, A. S., Kaiser, L. R., Albelda, S. M. (2005) Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 11, 6713-6721.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 31
    • 84886944739 scopus 로고    scopus 로고
    • Immune effects of 5-fluorouracil: Ambivalence matters
    • Ghiringhelli, F., Bruchard, M., Apetoh, L. (2013) Immune effects of 5-fluorouracil: ambivalence matters. Oncoimmunology 2, e23139.
    • (2013) Oncoimmunology , vol.2
    • Ghiringhelli, F.1    Bruchard, M.2    Apetoh, L.3
  • 32
    • 77956680680 scopus 로고    scopus 로고
    • A novel chemoimmunomodulating property of docetaxel: Suppression of myeloid-derived suppressor cells in tumor bearers
    • Kodumudi, K. N., Woan, K., Gilvary, D. L., Sahakian, E., Wei, S., Djeu, J. Y. (2010) A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin. Cancer Res. 16, 4583-4594.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 4583-4594
    • Kodumudi, K.N.1    Woan, K.2    Gilvary, D.L.3    Sahakian, E.4    Wei, S.5    Djeu, J.Y.6
  • 33
    • 84874232680 scopus 로고    scopus 로고
    • Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model
    • Sevko, A., Michels, T., Vrohlings, M., Umansky, L., Beckhove, P., Kato, M., Shurin, G. V., Shurin, M. R., Umansky, V. (2013) Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model. J. Immunol. 190, 2464-2471.
    • (2013) J. Immunol. , vol.190 , pp. 2464-2471
    • Sevko, A.1    Michels, T.2    Vrohlings, M.3    Umansky, L.4    Beckhove, P.5    Kato, M.6    Shurin, G.V.7    Shurin, M.R.8    Umansky, V.9
  • 34
    • 77950498798 scopus 로고    scopus 로고
    • Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2=-deoxycytidine
    • Daurkin, I., Eruslanov, E., Vieweg, J., Kusmartsev, S. (2010) Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2=-deoxycytidine. Cancer Immunol. Immunother. 59, 697-706.
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 697-706
    • Daurkin, I.1    Eruslanov, E.2    Vieweg, J.3    Kusmartsev, S.4
  • 36
    • 84860902300 scopus 로고    scopus 로고
    • Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo
    • Rosborough, B. R., Castellaneta, A., Natarajan, S., Thomson, A. W., Turnquist. H. R. (2012) Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo. J. Leukoc. Biol. 91, 701-709.
    • (2012) J. Leukoc. Biol. , vol.91 , pp. 701-709
    • Rosborough, B.R.1    Castellaneta, A.2    Natarajan, S.3    Thomson, A.W.4    Turnquist, H.R.5
  • 37
    • 0030068375 scopus 로고    scopus 로고
    • Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen
    • Lin, K. Y., Guarnieri, F. G., Staveley-O'Carroll, K. F., Levitsky, H. I., August, J. T., Pardoll, D. M., Wu, T. C. (1996) Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen. Cancer Res. 56, 21-26.
    • (1996) Cancer Res. , vol.56 , pp. 21-26
    • Lin, K.Y.1    Guarnieri, F.G.2    Staveley-O'Carroll, K.F.3    Levitsky, H.I.4    August, J.T.5    Pardoll, D.M.6    Wu, T.C.7
  • 38
    • 0037424159 scopus 로고    scopus 로고
    • Immunisation with modified HPV16 E7 genes against mouse oncogenic TC-1 cell sublines with downregulated expression of MHC class I molecules
    • Šmahel, M., Šíma, P., Ludvíková, V., Marinov, I., Pokorná D., Vonka, V. (2003) Immunisation with modified HPV16 E7 genes against mouse oncogenic TC-1 cell sublines with downregulated expression of MHC class I molecules. Vaccine 21, 1125-1136.
    • (2003) Vaccine , vol.21 , pp. 1125-1136
    • Šmahel, M.1    Šíma, P.2    Ludvíková, V.3    Marinov, I.4    Pokorná, D.5    Vonka, V.6
  • 39
    • 0030860498 scopus 로고    scopus 로고
    • Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model
    • Foster, B. A., Gingrich, J. R., Kwon, E. D., Madias, C., Greenberg, N. M. (1997) Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model. Cancer Res. 57, 3325-3330.
    • (1997) Cancer Res. , vol.57 , pp. 3325-3330
    • Foster, B.A.1    Gingrich, J.R.2    Kwon, E.D.3    Madias, C.4    Greenberg, N.M.5
  • 40
    • 38849093198 scopus 로고    scopus 로고
    • IL-12 immunotherapy of minimal residual disease in murine models of HPV16-associated tumours: Induction of immune responses, cytokine production and kinetics of immune cell subsets
    • Indrová, M., Bieblová, J., Bubeník, J., Reiniš, M. (2008) IL-12 immunotherapy of minimal residual disease in murine models of HPV16-associated tumours: induction of immune responses, cytokine production and kinetics of immune cell subsets. Int. J. Oncol. 32, 499-507.
    • (2008) Int. J. Oncol. , vol.32 , pp. 499-507
    • Indrová, M.1    Bieblová, J.2    Bubeník, J.3    Reiniš, M.4
  • 42
    • 77951086882 scopus 로고    scopus 로고
    • 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
    • Vincent, J., Mignot, G., Chalmin, F., Ladoire, S., Bruchard, M., Chevriaux, A., Martin, F., Apetoh, L., Rébé, C., Ghiringhelli, F. (2010) 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res. 70, 3052-3061.
    • (2010) Cancer Res. , vol.70 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3    Ladoire, S.4    Bruchard, M.5    Chevriaux, A.6    Martin, F.7    Apetoh, L.8    Rébé, C.9    Ghiringhelli, F.10
  • 43
    • 84862120892 scopus 로고    scopus 로고
    • Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner
    • Michels, T., Shurin, G. V., Naiditch, H., Sevko, A., Umansky, V., Shurin, M. R. (2012) Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner. J. Immunotoxicol. 9, 292-300.
    • (2012) J. Immunotoxicol. , vol.9 , pp. 292-300
    • Michels, T.1    Shurin, G.V.2    Naiditch, H.3    Sevko, A.4    Umansky, V.5    Shurin, M.R.6


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