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Volumn 6, Issue 10, 2010, Pages 1577-1589

Immunotherapy of MHC class I-deficient tumors

Author keywords

antigen presenting machinery; antitumor immunotherapy; epigenetics; MHC class I expression; tumor vaccine

Indexed keywords

CYTOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

EID: 78149422805     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.10.128     Document Type: Review
Times cited : (18)

References (97)
  • 2
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD: The immunobiology of cancer immunosurveillance and immunoediting. Immunity 21(2), 137-148 (2004).
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 3
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumor environment and their therapeutic relevance
    • Zou W: Immunosuppressive networks in the tumor environment and their therapeutic relevance. Nat. Rev. Cancer 5(4), 263-274 (2005).
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.4 , pp. 263-274
    • Zou, W.1
  • 5
    • 50649085453 scopus 로고    scopus 로고
    • Regressing and progressing metastatic lesions: Resistance to immunotherapy is predetermined by irreversible HLA class i antigen alterations
    • Aptsiauri N, Carretero R, Garcia-Lora A et al.: Regressing and progressing metastatic lesions: resistance to immunotherapy is predetermined by irreversible HLA class I antigen alterations. Cancer Immunol. Immunother. 57(11), 1727-1733 (2008).
    • (2008) Cancer Immunol. Immunother. , vol.57 , Issue.11 , pp. 1727-1733
    • Aptsiauri, N.1    Carretero, R.2    Garcia-Lora, A.3
  • 6
    • 0033120466 scopus 로고    scopus 로고
    • HLA class i antigen downregulation in human cancers: T-cell immunotherapy revives an old story
    • Hicklin DJ, Marincola FM, Ferrone S: HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story. Mol. Med. Today 5(4), 178-186 (1999).
    • (1999) Mol. Med. Today , vol.5 , Issue.4 , pp. 178-186
    • Hicklin, D.J.1    Marincola, F.M.2    Ferrone, S.3
  • 7
    • 0031080901 scopus 로고    scopus 로고
    • Implications for immunosurveillance of altered HLA class i phenotypes in human tumours
    • Garrido F, Ruiz-Cabello F, Cabrera T et al.: Implications for immunosurveillance of altered HLA class I phenotypes in human tumours. Immunol. Today 18(2), 89-95 (1997).
    • (1997) Immunol. Today , vol.18 , Issue.2 , pp. 89-95
    • Garrido, F.1    Ruiz-Cabello, F.2    Cabrera, T.3
  • 8
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of "tumor escape" phenotypes
    • Khong HT, Restifo NP: Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Immunology 3(11), 999-1005 (2002).
    • (2002) Immunology , vol.3 , Issue.11 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 9
    • 74949117253 scopus 로고    scopus 로고
    • The prognostic role of classical and nonclassical MHC class i expression in endometrial cancer
    • Bijen CB, Bantema-Joppe EJ, de Jong RA et al.: The prognostic role of classical and nonclassical MHC class I expression in endometrial cancer. Int. J. Cancer 126(6), 1417-1427 (2010).
    • (2010) Int. J. Cancer , vol.126 , Issue.6 , pp. 1417-1427
    • Bijen, C.B.1    Bantema-Joppe, E.J.2    De Jong, R.A.3
  • 10
    • 27944434228 scopus 로고    scopus 로고
    • Molecular mechanisms of HLA class i antigen abnormalities following viral infection and transformation
    • Seliger B, Ritz U, Ferrone S: Molecular mechanisms of HLA class I antigen abnormalities following viral infection and transformation. Int. J. Cancer 118(1), 129-138 (2006).
    • (2006) Int. J. Cancer , vol.118 , Issue.1 , pp. 129-138
    • Seliger, B.1    Ritz, U.2    Ferrone, S.3
  • 11
    • 0037710132 scopus 로고    scopus 로고
    • Prospects of immunotherapy of MHC class I-deficient tumours
    • Bubeník J: Prospects for immunotherapy of MHC class I-defcient tumours. Folia Biol. (Praha) 49(3), 95-99 (2003). (Pubitemid 36818238)
    • (2003) Folia Biologica , vol.49 , Issue.3 , pp. 95-99
    • Bubenik, J.1
  • 12
    • 0032503029 scopus 로고    scopus 로고
    • Viral strategies of immune evasion
    • Ploegh HL: Viral strategies of immune evasion. Science 280(5361), 248-253 (1998).
    • (1998) Science , vol.280 , Issue.5361 , pp. 248-253
    • Ploegh, H.L.1
  • 13
    • 0037074008 scopus 로고    scopus 로고
    • HIV-1 Nef downregulates MHC-I by a PACS-1-and PI3K-regulated ARF6 endocytic pathway
    • Blagoveshchenskaya AD, Thomas L, Feliciangeli SF et al.: HIV-1 Nef downregulates MHC-I by a PACS-1-and PI3K-regulated ARF6 endocytic pathway. Cell 111(6), 853-866 (2002).
    • (2002) Cell , vol.111 , Issue.6 , pp. 853-866
    • Blagoveshchenskaya, A.D.1    Thomas, L.2    Feliciangeli, S.F.3
  • 14
    • 77956337898 scopus 로고    scopus 로고
    • Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells
    • Suárez-Alvarez B, Rodriguez RM, Calvanese V et al.: Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells. PLoS ONE 5(14), E10192 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.14
    • Suárez-Alvarez, B.1    Rodriguez, R.M.2    Calvanese, V.3
  • 16
    • 2342514891 scopus 로고    scopus 로고
    • Immune system and prognosis in colorectal cancer: A detailed immunohistochemical analysis
    • Menon AG, Janssen-van Rhijn CM, Morreau H et al.: Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis. Lab. Invest. 84(4), 493-501 (2004).
    • (2004) Lab. Invest. , vol.84 , Issue.4 , pp. 493-501
    • Menon, A.G.1    Janssen-Van Rhijn, C.M.2    Morreau, H.3
  • 17
    • 0345801302 scopus 로고    scopus 로고
    • Tumor MHC class i downregulation and immunotherapy (review)
    • Bubenik J: Tumor MHC class I downregulation and immunotherapy (review). Oncol. Rep. 10(6), 2005-2008 (2003).
    • (2003) Oncol. Rep. , vol.10 , Issue.6 , pp. 2005-2008
    • Bubenik, J.1
  • 18
    • 4444370699 scopus 로고    scopus 로고
    • HLA class i antigen expression in malignant cells: Why does it not always correlate with CTL-mediated lysis?
    • Chang CC, Campoli M, Ferrone S: HLA class I antigen expression in malignant cells: why does it not always correlate with CTL-mediated lysis? Curr. Opin. Immunol. 16(5), 644-650 (2004).
    • (2004) Curr. Opin. Immunol. , vol.16 , Issue.5 , pp. 644-650
    • Chang, C.C.1    Campoli, M.2    Ferrone, S.3
  • 19
    • 0026507161 scopus 로고
    • Altered binding of regulatory factors to HLA class i enhancer sequence in human tumor cell lines lacking class i antigen expression
    • Blanchet O, Bourge JF, Zinszner H et al.: Altered binding of regulatory factors to HLA class I enhancer sequence in human tumor cell lines lacking class I antigen expression. Proc. Natl Acad. Sci. USA 89(8), 3488-3492 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , Issue.8 , pp. 3488-3492
    • Blanchet, O.1    Bourge, J.F.2    Zinszner, H.3
  • 20
    • 0024363758 scopus 로고
    • 2 microglobulin by interferon-γ
    • 2 microglobulin by interferon-γ. EMBO J. 8(2), 475-481 (1989).
    • (1989) EMBO J. , vol.8 , Issue.2 , pp. 475-481
    • Klar, D.1    Hämmerling, G.J.2
  • 21
    • 0026515435 scopus 로고
    • A defect in the presentation of intracellular viral antigens is restored by interferon-γ in cell lines with impaired major histocompatibility complex class i assembly Eur
    • Sibille C, Gould K, Hämmerling G et al.: A defect in the presentation of intracellular viral antigens is restored by interferon-γ in cell lines with impaired major histocompatibility complex class I assembly Eur. J. Immunol. 22(2), 433-440 (1992).
    • (1992) J. Immunol. , vol.22 , Issue.2 , pp. 433-440
    • Sibille, C.1    Gould, K.2    Hämmerling, G.3
  • 23
    • 0028024224 scopus 로고
    • Comparison of cell lines defcient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing
    • Gabathuler R, Reid G, Kolaitis G et al.: Comparison of cell lines defcient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing. J. Exp. Med. 180(4), 1415-1425 (1994).
    • (1994) J. Exp. Med. , vol.180 , Issue.4 , pp. 1415-1425
    • Gabathuler, R.1    Reid, G.2    Kolaitis, G.3
  • 24
    • 23844530176 scopus 로고    scopus 로고
    • Identifcation of mechanisms underlying transporter associated with antigen processing defciency in metastatic murine carcinomas
    • Setiadi AF, David MD, Chen SS et al.: Identifcation of mechanisms underlying transporter associated with antigen processing defciency in metastatic murine carcinomas. Cancer Res. 65(16), 7485-92 (2005).
    • (2005) Cancer Res. , vol.65 , Issue.16 , pp. 7485-92
    • Setiadi, A.F.1    David, M.D.2    Chen, S.S.3
  • 25
    • 0035137084 scopus 로고    scopus 로고
    • Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines
    • Seliger B, Schreiber K, Delp K et al.: Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines. Tissue Antigens 57(1), 39-45 (2001).
    • (2001) Tissue Antigens , vol.57 , Issue.1 , pp. 39-45
    • Seliger, B.1    Schreiber, K.2    Delp, K.3
  • 26
    • 0037639186 scopus 로고    scopus 로고
    • MHC class I-defcient metastatic tumor variants immunoselected by T lymphocytes originate from the coordinated downregulation of APM components
    • Garcia-Lora A, Martinez M, Algarra I et al.: MHC class I-defcient metastatic tumor variants immunoselected by T lymphocytes originate from the coordinated downregulation of APM components. Int. J. Cancer 106(4), 521-527 (2003).
    • (2003) Int. J. Cancer , vol.106 , Issue.4 , pp. 521-527
    • Garcia-Lora, A.1    Martinez, M.2    Algarra, I.3
  • 27
    • 0033792590 scopus 로고    scopus 로고
    • Coordinate downregulation of multiple MHC class i antigen processing genes in chemical-induced murine tumor cell lines of distinct origin
    • Seliger B, Wollscheid U, Momburg F et al.: Coordinate downregulation of multiple MHC class I antigen processing genes in chemical-induced murine tumor cell lines of distinct origin. Tissue Antigens 56(4), 327-336 (2000).
    • (2000) Tissue Antigens , vol.56 , Issue.4 , pp. 327-336
    • Seliger, B.1    Wollscheid, U.2    Momburg, F.3
  • 28
    • 0025936182 scopus 로고
    • Frequent down-regulation of major histocompatibility class i antigen expression on individual micrometastatic carcinoma cells
    • Pantel K, Schlimok G, Kutter D et al.: Frequent down-regulation of major histocompatibility class I antigen expression on individual micrometastatic carcinoma cells. Cancer Res. 51(17), 4712-4715 (1991).
    • (1991) Cancer Res. , vol.51 , Issue.17 , pp. 4712-4715
    • Pantel, K.1    Schlimok, G.2    Kutter, D.3
  • 29
    • 0141452056 scopus 로고    scopus 로고
    • HLA class i expression in bladder carcinomas
    • Cabrera T, Pedrajas G, Cozar JM et al.: HLA class I expression in bladder carcinomas. Tissue Antigens 62(4), 324-327 (2003).
    • (2003) Tissue Antigens , vol.62 , Issue.4 , pp. 324-327
    • Cabrera, T.1    Pedrajas, G.2    Cozar, J.M.3
  • 30
    • 0345275861 scopus 로고    scopus 로고
    • Retinoids act as multistep modulators of the major histocompatibility class i presentation pathway and sensitize neuroblastomas to cytotoxic lymphocytes
    • Vertuani S, De Geer A, Levitsky V et al.: Retinoids act as multistep modulators of the major histocompatibility class I presentation pathway and sensitize neuroblastomas to cytotoxic lymphocytes. Cancer Res. 63(22), 8006-8013 (2003).
    • (2003) Cancer Res. , vol.63 , Issue.22 , pp. 8006-8013
    • Vertuani, S.1    De Geer, A.2    Levitsky, V.3
  • 31
    • 53549116447 scopus 로고    scopus 로고
    • HLA antigen changes in malignant cells: Epigenetic mechanisms and biologic signifcance
    • Campoli M, Ferrone S: HLA antigen changes in malignant cells: epigenetic mechanisms and biologic signifcance. Oncogene 27(45), 5869-5885 (2008).
    • (2008) Oncogene , vol.27 , Issue.45 , pp. 5869-5885
    • Campoli, M.1    Ferrone, S.2
  • 32
    • 0035886022 scopus 로고    scopus 로고
    • Expression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2′-deoxycytidine treatment
    • DOI 10.1002/ijc.1452
    • Serrano A, Tanzarella S, Lionello I et al.: Rexpression of HLA class I antigens and restoration of antigen-specifc CTL response in melanoma cells following 5-aza-2́-deoxycytidine treatment. Int. J. Cancer 94(2), 243-251 (2001). (Pubitemid 32911420)
    • (2001) International Journal of Cancer , vol.94 , Issue.2 , pp. 243-251
    • Serrano, A.1    Tanzarella, S.2    Lionello, I.3    Mendez, R.4    Traversari, C.5    Ruiz-Cabello, F.6    Garrido, F.7
  • 33
    • 0034794672 scopus 로고    scopus 로고
    • DNA hypermethylation is a mechanism for loss of expression of the HLA class i genes in human esophageal squamous cell carcinomas
    • Nie Y, Yang G, Song Y et al.: DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas. Carcinogenesis 22(10), 1615-1623 (2001).
    • (2001) Carcinogenesis , vol.22 , Issue.10 , pp. 1615-1623
    • Nie, Y.1    Yang, G.2    Song, Y.3
  • 34
    • 36049035588 scopus 로고    scopus 로고
    • Epigenetic control of the immune escape mechanisms in malignant carcinomas
    • Setiadi AF, David MD, Seipp RP et al.: Epigenetic control of the immune escape mechanisms in malignant carcinomas. Mol. Cell Biol. 27(22), 7886-7894 (2007).
    • (2007) Mol. Cell Biol. , vol.27 , Issue.22 , pp. 7886-7894
    • Setiadi, A.F.1    David, M.D.2    Seipp, R.P.3
  • 35
    • 37849033441 scopus 로고    scopus 로고
    • Induction of MHC class i molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours
    • Manning J, Indrova M, Lubyova B et al.: Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. Immunology 123 (2), 218-227 (2008).
    • (2008) Immunology , vol.123 , Issue.2 , pp. 218-227
    • Manning, J.1    Indrova, M.2    Lubyova, B.3
  • 36
    • 57149086295 scopus 로고    scopus 로고
    • Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors
    • Setiadi AF, Omilusik K, David MD et al.: Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors. Cancer Res. 68(23), 9601-9607 (2008).
    • (2008) Cancer Res. , vol.68 , Issue.23 , pp. 9601-9607
    • Setiadi, A.F.1    Omilusik, K.2    David, M.D.3
  • 37
    • 43149097365 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class i antigen presentation by melanoma cells
    • Khan AN, Gregorie CJ, Tomasi TB: Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells. Cancer Immunol. Immunother. 57(5), 647-654 (2008).
    • (2008) Cancer Immunol. Immunother. , vol.57 , Issue.5 , pp. 647-654
    • Khan, A.N.1    Gregorie, C.J.2    Tomasi, T.B.3
  • 38
    • 44649127394 scopus 로고    scopus 로고
    • Histone deacetylase regulation of immune gene expression in tumor cells
    • Khan AN, Tomasi TB: Histone deacetylase regulation of immune gene expression in tumor cells. Immunol. Res. 40(2), 164-178 (2008).
    • (2008) Immunol. Res. , vol.40 , Issue.2 , pp. 164-178
    • Khan, A.N.1    Tomasi, T.B.2
  • 39
    • 33745599088 scopus 로고    scopus 로고
    • Epigenetic regulation of immune escape genes in cancer
    • Tomasi TB, Magner WJ, Khan AN: Epigenetic regulation of immune escape genes in cancer. Cancer Immunol. Immunother. 55(10), 1159-1184 (2006).
    • (2006) Cancer Immunol. Immunother. , vol.55 , Issue.10 , pp. 1159-1184
    • Tomasi, T.B.1    Magner, W.J.2    Khan, A.N.3
  • 40
    • 0022616253 scopus 로고
    • Selective rejection of H-2-defcient lymphoma variants suggests alternative immune defence strategy
    • Karre K, Ljunggren HG, Piontek G et al.: Selective rejection of H-2-defcient lymphoma variants suggests alternative immune defence strategy. Nature 319(6055), 675-678 (1986).
    • (1986) Nature , vol.319 , Issue.6055 , pp. 675-678
    • Karre, K.1    Ljunggren, H.G.2    Piontek, G.3
  • 41
    • 0036812626 scopus 로고    scopus 로고
    • The innate immune response to tumors and its role in the induction of T-cell immunity
    • Diefenbach A, Raulet DH: The innate immune response to tumors and its role in the induction of T-cell immunity. Immunol. Rev. 188(1), 9-21 (2002).
    • (2002) Immunol. Rev. , vol.188 , Issue.1 , pp. 9-21
    • Diefenbach, A.1    Raulet, D.H.2
  • 42
    • 0034775028 scopus 로고    scopus 로고
    • Dendritic cell-tumor coculturing vaccine can induce antitumor immunity through both NK and CTL interaction
    • Kim KD, Choi SC, Kim A et al.: Dendritic cell-tumor coculturing vaccine can induce antitumor immunity through both NK and CTL interaction. Int. Immunopharmacol. 1(12), 2117-2129 (2001).
    • (2001) Int. Immunopharmacol. , vol.1 , Issue.12 , pp. 2117-2129
    • Kim, K.D.1    Choi, S.C.2    Kim, A.3
  • 44
    • 27944441722 scopus 로고    scopus 로고
    • Immunosurveillance is active in colorectal cancer as downregulation but not complete loss of MHC class i expression correlates with a poor prognosis
    • Watson NF, Ramage JM, Madjd Z et al.: Immunosurveillance is active in colorectal cancer as downregulation but not complete loss of MHC class I expression correlates with a poor prognosis. Int. J.Cancer 118(1), 6-10 (2006).
    • (2006) Int. J.Cancer , vol.118 , Issue.1 , pp. 6-10
    • Watson, N.F.1    Ramage, J.M.2    Madjd, Z.3
  • 45
    • 50149114278 scopus 로고    scopus 로고
    • Survival of ovarian cancer patients overexpressing the tumor antigen p53 is diminished in case of MHC class i down-regulation
    • Leffers N, Lambeck AJ, de Graeff P et al.: Survival of ovarian cancer patients overexpressing the tumor antigen p53 is diminished in case of MHC class I down-regulation. Gynecol. Oncol. 110(3), 365-373 (2008).
    • (2008) Gynecol. Oncol. , vol.110 , Issue.3 , pp. 365-373
    • Leffers, N.1    Lambeck, A.J.2    De Graeff, P.3
  • 46
    • 25444478689 scopus 로고    scopus 로고
    • Total loss of MHC class i is an independent indicator of good prognosis in breast cancer
    • Madjd Z, Spendlove I, Pinder SE et al.: Total loss of MHC class I is an independent indicator of good prognosis in breast cancer. Int. J. Cancer 117(2), 248-255 (2005).
    • (2005) Int. J. Cancer , vol.117 , Issue.2 , pp. 248-255
    • Madjd, Z.1    Spendlove, I.2    Pinder, S.E.3
  • 47
    • 10644285782 scopus 로고    scopus 로고
    • Natural killer cells infltrating colorectal cancer and MHC class i expression
    • Sandel MH, Speetjens FM, Menon AG et al.: Natural killer cells infltrating colorectal cancer and MHC class I expression. Mol. Immunol. 42(4), 541-546 (2005).
    • (2005) Mol. Immunol. , vol.42 , Issue.4 , pp. 541-546
    • Sandel, M.H.1    Speetjens, F.M.2    Menon, A.G.3
  • 48
    • 60749096114 scopus 로고    scopus 로고
    • HPV 16-associated tumours: IL-12 can repair the absence of cytotoxic and proliferative responses of tumor infltrating cells after chemotherapy Int
    • Indrová M, Bieblová J, Rossowska J et al.: HPV 16-associated tumours: IL-12 can repair the absence of cytotoxic and proliferative responses of tumor infltrating cells after chemotherapy Int. J. Oncol. 34(1), 173-179 (2009).
    • (2009) J. Oncol. , vol.34 , Issue.1 , pp. 173-179
    • Indrová, M.1    Bieblová, J.2    Rossowska, J.3
  • 49
    • 27144524046 scopus 로고    scopus 로고
    • NK cells infltrating a MHC class I-defcient lung adenocarcinoma display impaired cytotoxic activity toward autologous tumor cells associated with altered NK cell-triggering receptors
    • Le Maux Chansac B, Moretta A, Vergnon I et al.: NK cells infltrating a MHC class I-defcient lung adenocarcinoma display impaired cytotoxic activity toward autologous tumor cells associated with altered NK cell-triggering receptors. J. Immunol. 175(9), 5790-5798 (2005).
    • (2005) J. Immunol. , vol.175 , Issue.9 , pp. 5790-5798
    • Le Maux Chansac, B.1    Moretta, A.2    Vergnon, I.3
  • 50
    • 24344505476 scopus 로고    scopus 로고
    • Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysis
    • Moretta L, Bottino C, Pende D et al.: Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysis. Immunol. Lett. 100(1), 7-13 (2005).
    • (2005) Immunol. Lett. , vol.100 , Issue.1 , pp. 7-13
    • Moretta, L.1    Bottino, C.2    Pende, D.3
  • 51
    • 0037126310 scopus 로고    scopus 로고
    • Tumor-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • Groh V, Wu J, Yee C et al.: Tumor-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 419(6908), 734-738 (2002).
    • (2002) Nature , vol.419 , Issue.6908 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3
  • 52
    • 0347627712 scopus 로고    scopus 로고
    • Evasion from NK cell immunity by MHC class i chain-related molecules expressing colon adenocarcinoma
    • Doubrovina ES, Doubrovin MM, Vider E et al.: Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J. Immunol. 171(12), 6891-6899 (2003).
    • (2003) J. Immunol. , vol.171 , Issue.12 , pp. 6891-6899
    • Doubrovina, E.S.1    Doubrovin, M.M.2    Vider, E.3
  • 53
    • 68549107694 scopus 로고    scopus 로고
    • Down-regulation of HLA Class i and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells
    • Sers C, Kuner R, Falk CS et al.: Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells. Int. J. Cancer 125(7), 1626-1639 (2009).
    • (2009) Int. J. Cancer , vol.125 , Issue.7 , pp. 1626-1639
    • Sers, C.1    Kuner, R.2    Falk, C.S.3
  • 54
    • 34547667110 scopus 로고    scopus 로고
    • Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis
    • Rohner A, Langenkamp U, Siegler U et al.: Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis. Leuk. Res. 31(10), 1393-1402 (2007).
    • (2007) Leuk. Res. , vol.31 , Issue.10 , pp. 1393-1402
    • Rohner, A.1    Langenkamp, U.2    Siegler, U.3
  • 55
    • 28244502269 scopus 로고    scopus 로고
    • Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B
    • Skov S, Pedersen MT, Andresen L et al.: Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B. Cancer Res. 65(23), 11136-11145 (2005).
    • (2005) Cancer Res. , vol.65 , Issue.23 , pp. 11136-11145
    • Skov, S.1    Pedersen, M.T.2    Andresen, L.3
  • 56
    • 0346995357 scopus 로고    scopus 로고
    • MHC class i status of tumours and design of immunotherapeutic strategies
    • Bubenik J, Vonka V: MHC class I status of tumours and design of immunotherapeutic strategies. Immunol. Lett. 90(2-3), 177-178 (2003).
    • (2003) Immunol. Lett. , vol.90 , Issue.2-3 , pp. 177-178
    • Bubenik, J.1    Vonka, V.2
  • 57
    • 14944368161 scopus 로고    scopus 로고
    • MHC class i down-regulation: Tumor escape from immune surveillance? (review)
    • Bubenik J: MHC class I down-regulation: tumor escape from immune surveillance? (review). Int. J. Oncol. 25(2), 487-491 (2004).
    • (2004) Int. J. Oncol. , vol.25 , Issue.2 , pp. 487-491
    • Bubenik, J.1
  • 58
    • 10744220243 scopus 로고    scopus 로고
    • Natural killer cells activated by MHC class I(low) targets prime dendritic cells to induce protective CD8 T cell responses
    • Mocikat R, Braumüller H, Gumy A et al.: Natural killer cells activated by MHC class I(low) targets prime dendritic cells to induce protective CD8 T cell responses. Immunity 19(4), 561-569 (2003).
    • (2003) Immunity , vol.19 , Issue.4 , pp. 561-569
    • Mocikat, R.1    Braumüller, H.2    Gumy, A.3
  • 60
    • 0037435981 scopus 로고    scopus 로고
    • Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16
    • Bubenik J, Mikyskova R, Vonka V et al.: Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16. Vaccine 21(9-10), 891-896 (2003).
    • (2003) Vaccine , vol.21 , Issue.9-10 , pp. 891-896
    • Bubenik, J.1    Mikyskova, R.2    Vonka, V.3
  • 61
    • 0036134175 scopus 로고    scopus 로고
    • Animal models for development of therapeutic HPV16 vaccines (review)
    • Bubenik J: Animal models for development of therapeutic HPV16 vaccines (review). Int. J. Oncol. 20(1), 207-212 (2002).
    • (2002) Int. J. Oncol. , vol.20 , Issue.1 , pp. 207-212
    • Bubenik, J.1
  • 62
    • 33644871720 scopus 로고    scopus 로고
    • Inhibitory effects of unmethylated CpG oligodeoxynucleotides on MHC class I-defcient and-profcient HPV16-associated tumours
    • Reinis M, Simova J, Bubenik J: Inhibitory effects of unmethylated CpG oligodeoxynucleotides on MHC class I-defcient and-profcient HPV16-associated tumours. Int. J. Cancer 118(7), 1836-1842 (2006).
    • (2006) Int. J. Cancer , vol.118 , Issue.7 , pp. 1836-1842
    • Reinis, M.1    Simova, J.2    Bubenik, J.3
  • 63
    • 77951926671 scopus 로고    scopus 로고
    • Therapy for minimal residual tumor disease: β-galactosylceramide inhibits the growth of recurrent HPV16-associated neoplasms after surgery and chemotherapy Int
    • Símová J, Indrová M, Bieblová J et al.: Therapy for minimal residual tumor disease: β-galactosylceramide inhibits the growth of recurrent HPV16-associated neoplasms after surgery and chemotherapy Int. J. Cancer 126(12), 2997-3004 (2010).
    • (2010) J. Cancer , vol.126 , Issue.12 , pp. 2997-3004
    • Símová, J.1    Indrová, M.2    Bieblová, J.3
  • 64
    • 33750607929 scopus 로고    scopus 로고
    • Induction of protective immunity to RM-1 prostate cancer cells with ALVAC-IL-2/IL-12/TNF-α combination therapy
    • Grant JF, Iwasawa T, Sinn HW et al.: Induction of protective immunity to RM-1 prostate cancer cells with ALVAC-IL-2/IL-12/TNF-α combination therapy Int. J. Cancer 119(11), 2632-2641 (2006).
    • (2006) Int. J. Cancer , vol.119 , Issue.11 , pp. 2632-2641
    • Grant, J.F.1    Iwasawa, T.2    Sinn, H.W.3
  • 65
    • 0032520919 scopus 로고    scopus 로고
    • Interleukin 12 gene therapy of MHC-negative murine melanoma metastases
    • Nanni P, Rossi I, De Giovanni C et al.: Interleukin 12 gene therapy of MHC-negative murine melanoma metastases. Cancer Res. 58(6), 1225-1230 (1998).
    • (1998) Cancer Res. , vol.58 , Issue.6 , pp. 1225-1230
    • Nanni, P.1    Rossi, I.2    De Giovanni, C.3
  • 66
    • 0028205094 scopus 로고
    • In vivo priming of two distinct antitumor effector populations: The role of MHC class i expression
    • Levitsky HI, Lazenby A, Hayashi RJ et al.: In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression. J. Exp. Med. 179(4), 1215-1224 (1994).
    • (1994) J. Exp. Med. , vol.179 , Issue.4 , pp. 1215-1224
    • Levitsky, H.I.1    Lazenby, A.2    Hayashi, R.J.3
  • 67
    • 0034494538 scopus 로고    scopus 로고
    • Antitumor effects of the combination therapy with TNF-α gene-modifed tumor cells and interleukin 12 in a melanoma model in mice
    • Lasek W, Mackiewicz A, Czajka A et al.: Antitumor effects of the combination therapy with TNF-α gene-modifed tumor cells and interleukin 12 in a melanoma model in mice. Cancer Gene Ther. 7(12), 1581-1590 (2000).
    • (2000) Cancer Gene Ther. , vol.7 , Issue.12 , pp. 1581-1590
    • Lasek, W.1    MacKiewicz, A.2    Czajka, A.3
  • 68
    • 0041524186 scopus 로고    scopus 로고
    • + T cells NK cells and IFN-γ are important for control of tumor with downregulated MHC class i expression by DNA vaccination
    • + T cells, NK cells and IFN-γ are important for control of tumor with downregulated MHC class I expression by DNA vaccination. Gene Ther. 10(16), 1311-1320 (2003).
    • (2003) Gene Ther. , vol.10 , Issue.16 , pp. 1311-1320
    • Cheng, W.F.1    Hung, C.F.2    Lin, K.Y.3
  • 69
    • 3442875581 scopus 로고    scopus 로고
    • Naked RNA vaccine controls tumors with down-regulated MHC class i expression through NK cells and perforin-dependent pathways
    • Cheng WF, Hung CF, Lee CN et al.: Naked RNA vaccine controls tumors with down-regulated MHC class I expression through NK cells and perforin-dependent pathways. Eur. J. Immunol. 34(7), 1892-1900 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , Issue.7 , pp. 1892-1900
    • Cheng, W.F.1    Hung, C.F.2    Lee, C.N.3
  • 70
    • 35449004531 scopus 로고    scopus 로고
    • Combination of intratumoral injections of vaccinia virus MVA expressing GM-CSF and immunization with DNA vaccine prolongs the survival of mice bearing HPV16 induced tumors with downregulated expression of MHC class i molecules
    • Nemeckova S, Smahel M, Hainz P et al.: Combination of intratumoral injections of vaccinia virus MVA expressing GM-CSF and immunization with DNA vaccine prolongs the survival of mice bearing HPV16 induced tumors with downregulated expression of MHC class I molecules. Neoplasma 54(4), 326-333 (2007).
    • (2007) Neoplasma , vol.54 , Issue.4 , pp. 326-333
    • Nemeckova, S.1    Smahel, M.2    Hainz, P.3
  • 72
    • 0034494545 scopus 로고    scopus 로고
    • The expression of CD70 and CD80 by gene-modifed tumor cells induces an antitumor response depending on the MHC status
    • Douin-Echinard V, Bornes S, Rochaix P et al.: The expression of CD70 and CD80 by gene-modifed tumor cells induces an antitumor response depending on the MHC status. Cancer Gene Ther. 7(12), 1543-1556 (2000).
    • (2000) Cancer Gene Ther. , vol.7 , Issue.12 , pp. 1543-1556
    • Douin-Echinard, V.1    Bornes, S.2    Rochaix, P.3
  • 73
    • 53549124398 scopus 로고    scopus 로고
    • NKG2D ligands in tumor immunity
    • Nausch N, Cerwenka A: NKG2D ligands in tumor immunity. Oncogene 27(45), 5944-5958 (2008).
    • (2008) Oncogene , vol.27 , Issue.45 , pp. 5944-5958
    • Nausch, N.1    Cerwenka, A.2
  • 74
    • 77749245811 scopus 로고    scopus 로고
    • In vivo tumor cell rejection induced by NK cell inhibitory receptor blockade: Maintained tolerance to normal cells even in the presence of IL-2
    • Vahlne G, Lindholm K, Meier A et al.: In vivo tumor cell rejection induced by NK cell inhibitory receptor blockade: maintained tolerance to normal cells even in the presence of IL-2. Eur. J. Immunol. 40(3), 813-823 (2010).
    • (2010) Eur. J. Immunol. , vol.40 , Issue.3 , pp. 813-823
    • Vahlne, G.1    Lindholm, K.2    Meier, A.3
  • 75
    • 44349125698 scopus 로고    scopus 로고
    • Glycopeptide dendrimers, part III: A review. Use of glycopeptide dendrimers in immunotherapy and diagnosis of cancer and viral diseases
    • Niederhafner P, Reinis M, Sebestík J et al.: Glycopeptide dendrimers, part III: a review. Use of glycopeptide dendrimers in immunotherapy and diagnosis of cancer and viral diseases. J. Pept. Sci. 14(5), 556-587 (2008).
    • (2008) J. Pept. Sci. , vol.14 , Issue.5 , pp. 556-587
    • Niederhafner, P.1    Reinis, M.2    Sebestík, J.3
  • 76
    • 77149172848 scopus 로고    scopus 로고
    • Induction of protective immunity against MHC class I-defcient, HPV16-associated tumours with peptide and dendritic cell-based vaccines
    • Reinis M, Stepanek I, Simova J et al.: Induction of protective immunity against MHC class I-defcient, HPV16-associated tumours with peptide and dendritic cell-based vaccines. Int. J. Oncol. 36(3), 545-551 (2010).
    • (2010) Int. J. Oncol. , vol.36 , Issue.3 , pp. 545-551
    • Reinis, M.1    Stepanek, I.2    Simova, J.3
  • 77
    • 0942277025 scopus 로고    scopus 로고
    • + and class I-HPV16-associated tumours expressing the E7 oncoprotein do not cross-react in immunization/challenge experiments
    • + and class I-HPV16-associated tumours expressing the E7 oncoprotein do not cross-react in immunization/challenge experiments. Folia Biol. (Praha) 49(6), 230-234 (2003).
    • (2003) Folia Biol. (Praha) , vol.49 , Issue.6 , pp. 230-234
    • Simova, J.1    Mikyskova, R.2    Vonka, V.3
  • 78
    • 34247890105 scopus 로고    scopus 로고
    • Immunisation with MHC class I-negative but not-positive HPV16-associated tumor cells inhibits growth of MHC class I-negative tumours
    • Reinis M, Símová J, Indrová M et al.: Immunisation with MHC class I-negative but not-positive HPV16-associated tumor cells inhibits growth of MHC class I-negative tumours. Int. J. Oncol. 30(4), 1011-1017 (2007).
    • (2007) Int. J. Oncol. , vol.30 , Issue.4 , pp. 1011-1017
    • Reinis, M.1    Símová, J.2    Indrová, M.3
  • 79
    • 0029092528 scopus 로고
    • Frequency of down-regulation of individual HLA-A and-B alleles in cervical carcinomas in relation to TAP-1 expression
    • Keating PJ, Cromme FV, Duggan-Keen M et al.: Frequency of down-regulation of individual HLA-A and-B alleles in cervical carcinomas in relation to TAP-1 expression. Br. J. Cancer 72(2), 405-411 (1995).
    • (1995) Br. J. Cancer , vol.72 , Issue.2 , pp. 405-411
    • Keating, P.J.1    Cromme, F.V.2    Duggan-Keen, M.3
  • 80
    • 33645749031 scopus 로고    scopus 로고
    • Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants
    • van Hall T, Wolpert EZ, van Veelen P et al.: Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants. Nat. Med. 12(4), 417-424 (2006).
    • (2006) Nat. Med. , vol.12 , Issue.4 , pp. 417-424
    • Van Hall, T.1    Wolpert, E.Z.2    Van Veelen, P.3
  • 81
    • 34248550778 scopus 로고    scopus 로고
    • + T cells specifc for hydrophobic TAP-and tapasin-independent peptides: The requirement for directed access into the ER
    • + T cells specifc for hydrophobic TAP-and tapasin-independent peptides: the requirement for directed access into the ER. Cancer Immunol. Immunother. 56(8), 1143-1152 (2007).
    • (2007) Cancer Immunol. Immunother. , vol.56 , Issue.8 , pp. 1143-1152
    • Aladin, F.1    Lautscham, G.2    Humphries, E.3
  • 82
    • 34548721063 scopus 로고    scopus 로고
    • Induction of protective CTL immunity against peptide transporter TAP-defcient tumors through dendritic cell vaccination
    • Chambers B, Grufman P, Fredriksson V et al.: Induction of protective CTL immunity against peptide transporter TAP-defcient tumors through dendritic cell vaccination. Cancer Res. 67(18), 8450-8455 (2007).
    • (2007) Cancer Res. , vol.67 , Issue.18 , pp. 8450-8455
    • Chambers, B.1    Grufman, P.2    Fredriksson, V.3
  • 84
    • 12244280810 scopus 로고    scopus 로고
    • Low-dose IFN-γ induces tumor MHC expression in metastatic malignant melanoma
    • Propper DJ, Chao D, Braybrooke JP et al.: Low-dose IFN-γ induces tumor MHC expression in metastatic malignant melanoma. Clin. Cancer Res. 9(1), 84-92 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , Issue.1 , pp. 84-92
    • Propper, D.J.1    Chao, D.2    Braybrooke, J.P.3
  • 85
    • 77950593165 scopus 로고    scopus 로고
    • IFN-γ-mediated upmodulation of MHC class i expression activates tumor-specifc immune response in a mouse model of prostate cancer
    • Martini M, Testi MG, Pasetto M et al.: IFN-γ-mediated upmodulation of MHC class I expression activates tumor-specifc immune response in a mouse model of prostate cancer. Vaccine 28(20), 3548-3557 (2010).
    • (2010) Vaccine , vol.28 , Issue.20 , pp. 3548-3557
    • Martini, M.1    Testi, M.G.2    Pasetto, M.3
  • 86
    • 61449083795 scopus 로고    scopus 로고
    • Interferon-γ down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-defcient melanoma by natural killer cells
    • Schwinn N, Vokhminova D, Sucker A et al.: Interferon-γ down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-defcient melanoma by natural killer cells. Int. J. Cancer 124(7), 1594-1604 (2009).
    • (2009) Int. J. Cancer , vol.124 , Issue.7 , pp. 1594-1604
    • Schwinn, N.1    Vokhminova, D.2    Sucker, A.3
  • 87
    • 14944352712 scopus 로고    scopus 로고
    • Immune escape phenotype of HPV16-associated tumours: MHC class i expression changes during progression and therapy Int
    • Mikyskova R, Bubenik J, Vonka V et al.: Immune escape phenotype of HPV16-associated tumours: MHC class I expression changes during progression and therapy Int. J. Oncol. 26(2), 521-527 (2005).
    • (2005) J. Oncol. , vol.26 , Issue.2 , pp. 521-527
    • Mikyskova, R.1    Bubenik, J.2    Vonka, V.3
  • 88
    • 20344404231 scopus 로고    scopus 로고
    • Natural killer cells play a role in MHC class i in vivo induction in tumor cells that are MHC negative in vitro
    • Kijima M, Saio M, Oyang GF et al.: Natural killer cells play a role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro. Int. J. Oncol. 26(3), 679-684 (2005).
    • (2005) Int. J. Oncol. , vol.26 , Issue.3 , pp. 679-684
    • Kijima, M.1    Saio, M.2    Oyang, G.F.3
  • 89
    • 33646834460 scopus 로고    scopus 로고
    • Interleukin-2 augmented activation of tumor associated macrophage plays the main role in MHC class i in vivo induction in tumor cells that are MHC negative in vitro
    • Ouyang GF, Saio M, Suwa T et al.: Interleukin-2 augmented activation of tumor associated macrophage plays the main role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro. Int. J. Oncol. 28(5), 1201-1208 (2006).
    • (2006) Int. J. Oncol. , vol.28 , Issue.5 , pp. 1201-1208
    • Ouyang, G.F.1    Saio, M.2    Suwa, T.3
  • 90
    • 33646704729 scopus 로고    scopus 로고
    • Radiation modulates the peptide repertoire, enhances MHC class i expression, and induces successful antitumor immunotherapy
    • Reits EA, Hodge JW, Herberts CA et al.: Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy J. Exp. Med. 203(5), 1259-1271 (2006).
    • (2006) J. Exp. Med. , vol.203 , Issue.5 , pp. 1259-1271
    • Reits, E.A.1    Hodge, J.W.2    Herberts, C.A.3
  • 91
    • 0034068643 scopus 로고    scopus 로고
    • TAP expression provides a general method for improving the recognition of malignant cells in vivo
    • Alimonti J, Zhang QJ, Gabathuler R et al.: TAP expression provides a general method for improving the recognition of malignant cells in vivo. Nat. Biotechnol. 18(5), 515-520 (2000).
    • (2000) Nat. Biotechnol. , vol.18 , Issue.5 , pp. 515-520
    • Alimonti, J.1    Zhang, Q.J.2    Gabathuler, R.3
  • 92
    • 33846898249 scopus 로고    scopus 로고
    • Tumour immunity and T cell memory are induced by low dose inoculation with a non-replicating adenovirus encoding TAP1
    • Lou Y, Seipp RP, Cai B et al.: Tumour immunity and T cell memory are induced by low dose inoculation with a non-replicating adenovirus encoding TAP1. Vaccine 25(12), 2331-2339 (2007).
    • (2007) Vaccine , vol.25 , Issue.12 , pp. 2331-2339
    • Lou, Y.1    Seipp, R.P.2    Cai, B.3
  • 93
    • 24744462113 scopus 로고    scopus 로고
    • Restoration of the expression of transporters associated with antigen processing in lung carcinoma increases tumor-specifc immune responses and survival
    • Lou Y, Vitalis TZ, Basha G et al.: Restoration of the expression of transporters associated with antigen processing in lung carcinoma increases tumor-specifc immune responses and survival. Cancer Res. 65(17), 7926-7933 (2005).
    • (2005) Cancer Res. , vol.65 , Issue.17 , pp. 7926-7933
    • Lou, Y.1    Vitalis, T.Z.2    Basha, G.3
  • 94
    • 40949151469 scopus 로고    scopus 로고
    • Combining the antigen processing components TAP and tapasin elicits enhanced tumor-free survival
    • Lou Y, Basha G, Seipp RP et al.: Combining the antigen processing components TAP and tapasin elicits enhanced tumor-free survival. Clin. Cancer Res. 14(5), 1494-1501 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.5 , pp. 1494-1501
    • Lou, Y.1    Basha, G.2    Seipp, R.P.3
  • 95
    • 17744385511 scopus 로고    scopus 로고
    • Metastatic MHC class I-negative mouse cells derived by transformation with human papillomavirus type 16
    • Smahel M, Sobotková E, Bubeník J et al.: Metastatic MHC class I-negative mouse cells derived by transformation with human papillomavirus type 16. Br. J. Cancer 84(3), 374-380 (2001).
    • (2001) Br. J. Cancer , vol.84 , Issue.3 , pp. 374-380
    • Smahel, M.1    Sobotková, E.2    Bubeník, J.3
  • 96
    • 0942264473 scopus 로고    scopus 로고
    • Immunization with live HPV-16-transformed mouse cells expressing the herpes simplex thymidine kinase and either GM-CSF or IL-2
    • Jinoch P, Zak R, Janousková O et al.: Immunization with live HPV-16-transformed mouse cells expressing the herpes simplex thymidine kinase and either GM-CSF or IL-2. Int. J. Oncol. 223(3), 775-783 (2003).
    • (2003) Int. J. Oncol. , vol.223 , Issue.3 , pp. 775-783
    • Jinoch, P.1    Zak, R.2    Janousková, O.3
  • 97
    • 13644274069 scopus 로고    scopus 로고
    • Enhancement of immunogenicity of HPV16 E7 oncogene by fusion with E. coli β-glucuronidase
    • Smahel M, Pokorná D, Macková J et al.: Enhancement of immunogenicity of HPV16 E7 oncogene by fusion with E. coli β-glucuronidase. J. Gene Med. 6(10), 1092-1101 (2004).
    • (2004) J. Gene Med. , vol.6 , Issue.10 , pp. 1092-1101
    • Smahel, M.1    Pokorná, D.2    MacKová, J.3


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