Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 1, 2014, Pages 186-193

  Myhren, Lene ^a   Nilssen, Ida Mostrøm ^a   Nicolas, Valérie ^b   Døskeland, Stein Ove ^a   Barratt, Gillian ^c   Herfindal, Lars ^a,d  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c UNIV PARIS SUD   (France)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Daunorubicin; Doxorubicin; Emetine; Folic acid; Leukaemia; Methotrexate

Indexed keywords

EID: 84899782639     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.04.002     Document Type: Article

References (41)

1. T.M. Allen, and P.R. Cullis Liposomal drug delivery systems: from concept to clinical applications Adv. Drug Deliv. Rev. 65 2013 36 48
2. R.D. Arnold, D.E. Mager, J.E. Slack, and R.M. Straubinger Effect of repetitive administration of Doxorubicin-containing liposomes on plasma pharmacokinetics and drug biodistribution in a rat brain tumor model Clin. Cancer Res. 11 2005 8856 8865
3. P. Buc-Calderon, M. Praet, J.M. Ruysschaert, and M. Roberfroid Increasing therapeutic effect and reducing toxicity of doxorubicin by N-acyl dehydroalanines Eur. J. Cancer Clin. Oncol. 25 1989 679 685
4. A. Burnett, M. Wetzler, and B. Lowenberg Therapeutic advances in acute myeloid leukemia J. Clin. Oncol. 29 2011 487 494
5. A.G. Carroll, H.J. Voeller, L. Sugars, and E.P. Gelmann P53 oncogene mutations in three human prostate cancer cell lines Prostate 23 1993 123 134
6. G.J. Charrois, and T.M. Allen Multiple injections of pegylated liposomal Doxorubicin: pharmacokinetics and therapeutic activity J. Pharmacol. Exp. Ther. 306 2003 1058 1067
7. B.A. de Koning, D.J. Lindenbergh-Kortleve, R. Pieters, H.A. Buller, I.B. Renes, and A.W. Einerhand Alterations in epithelial and mesenchymal intestinal gene expression during doxorubicin-induced mucositis in mice Dig. Dis. Sci. 52 2007 1814 1825
8. B.C. Ding, J.R. Whetstine, T.L. Witt, J.D. Schuetz, and L.H. Matherly Repression of human reduced folate carrier gene expression by wild type p53 J. Biol. Chem. 276 2001 8713 8719
9. E.J. Feldman, J.E. Lancet, J.E. Kolitz, E.K. Ritchie, G.J. Roboz, A.F. List, S.L. Allen, E. Asatiani, L.D. Mayer, C. Swenson, and A.C. Louie First-in-man study of CPX-351: a liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute myeloid leukemia J. Clin. Oncol. 29 2011 979 985
10. P. Fenaux, C. Chastang, S. Chevret, M. Sanz, H. Dombret, E. Archimbaud, M. Fey, C. Rayon, F. Huguet, J.J. Sotto, C. Gardin, P.C. Makhoul, P. Travade, E. Solary, N. Fegueux, D. Bordessoule, J.S. Miguel, H. Link, B. Desablens, A. Stamatoullas, E. Deconinck, F. Maloisel, S. Castaigne, C. Preudhomme, and L. Degos A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group Blood 94 1999 1192 1200
11. D.B. Fenske, and P.R. Cullis Entrapment of small molecules and nucleic acid-based drugs in liposomes Methods Enzymol. 391 2005 7 40
12. K.E. Foreman, J.N. Jesse 3rd, P.C. Kuo, and G.N. Gupta Emetine dihydrochloride: a novel therapy for bladder cancer J. Urol. 2013
13. A. Fritze, F. Hens, A. Kimpfler, R. Schubert, and R. Peschka-Suss Remote loading of doxorubicin into liposomes driven by a transmembrane phosphate gradient Biochim. Biophys. Acta 1758 2006 1633 1640
14. A. Gabizon, D. Tzemach, L. Mak, M. Bronstein, and A.T. Horowitz Dose dependency of pharmacokinetics and therapeutic efficacy of pegylated liposomal doxorubicin (DOXIL) in murine models J. Drug Target. 10 2002 539 548
15. G. Gausdal, B.T. Gjertsen, K.E. Fladmark, H. Demol, J. Vandekerckhove, and S.O. Doskeland Caspase-dependent, geldanamycin-enhanced cleavage of co-chaperone p23 in leukemic apoptosis Leukemia 18 2004 1989 1996
16. G. Gausdal, B.T. Gjertsen, E. McCormack, P. Van Damme, R. Hovland, C. Krakstad, O. Bruserud, K. Gevaert, J. Vandekerckhove, and S.O. Doskeland Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death Blood 111 2008 2866 2877
17. G. Gausdal, A. Wergeland, J. Skavland, E. Nguyen, F. Pendino, N. Rouhee, E. McCormack, L. Herfindal, R. Kleppe, U. Havemann, F. Schwede, O. Bruserud, B.T. Gjertsen, M. Lanotte, E. Segal-Bendirdjian, and S.O. Doskeland Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis Cell Death Dis. 4 2013 e516
18. L. Herfindal, L. Myhren, B.T. Gjertsen, S.O. Doskeland, and G. Gausdal Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen BMC Cancer 13 2013 341
19. A. Jemal, L.X. Clegg, E. Ward, L.A. Ries, X. Wu, P.M. Jamison, P.A. Wingo, H.L. Howe, R.N. Anderson, and B.K. Edwards Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival Cancer 101 2004 3 27
20. M. Lanotte, V. Martin-Thouvenin, S. Najman, P. Balerini, F. Valensi, and R. Berger NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3) Blood 77 1991 1080 1086
21. D.E. Larsson, S.B. Hassan, K. Oberg, and D. Granberg The cytotoxic effect of emetine and CGP-74514A studied with the hollow fiber model and ArrayScan assay in neuroendocrine tumors in vitro Anticancer Agents Med. Chem. 12 2012 783 790
22. B.E. Leach, J.H. Ford, and A.J. Whiffen Actidione, an antibiotic from Streptomyces griseus J. Am. Chem. Soc. 69 1947 474
23. C.P. Leamon, and P.S. Low Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells Biochem. J. 291 Pt 3 1993 855 860
24. R.J. Lee, and P.S. Low Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis J. Biol. Chem. 269 1994 3198 3204
25. B. Lowenberg, G.J. Ossenkoppele, W. van Putten, H.C. Schouten, C. Graux, A. Ferrant, P. Sonneveld, J. Maertens, M. Jongen-Lavrencic, M. von Lilienfeld-Toal, B.J. Biemond, E. Vellenga, M. van Marwijk Kooy, L.F. Verdonck, J. Beck, H. Dohner, A. Gratwohl, T. Pabst, and G. Verhoef High-dose daunorubicin in older patients with acute myeloid leukemia N. Engl. J. Med. 361 2009 1235 1248
26. C. Marie, and W.A. Petri Jr. Amoebic dysentery Clin. Evid. 2013 Online
27. Y. Matsuo, R.A. MacLeod, C.C. Uphoff, H.G. Drexler, C. Nishizaki, Y. Katayama, G. Kimura, N. Fujii, E. Omoto, M. Harada, and K. Orita Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23) Leukemia 11 1997 1469 1477
28. R.J. Mayer, R.B. Davis, C.A. Schiffer, D.T. Berg, B.L. Powell, P. Schulman, G.A. Omura, J.O. Moore, O.R. McIntyre, and E. Frei 3rd Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B N. Engl. J. Med. 331 1994 896 903
29. E. McCormack, I. Haaland, G. Venas, R.B. Forthun, S. Huseby, G. Gausdal, S. Knappskog, D.R. Micklem, J.B. Lorens, O. Bruserud, and B.T. Gjertsen Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia Leukemia 26 2012 910 917
30. A. Mehta, and V. Hoffbrand Haematology at a Glance third ed. 2010 Wiley-Blackwell Oxford
31. K. Mrozek, G. Marcucci, D. Nicolet, K.S. Maharry, H. Becker, S.P. Whitman, K.H. Metzeler, S. Schwind, Y.Z. Wu, J. Kohlschmidt, M.J. Pettenati, N.A. Heerema, A.W. Block, S.R. Patil, M.R. Baer, J.E. Kolitz, J.O. Moore, A.J. Carroll, R.M. Stone, R.A. Larson, and C.D. Bloomfield Prognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia J. Clin. Oncol. 30 2012 4515 4523
32. R.T. Proffitt, L.E. Williams, C.A. Presant, G.W. Tin, J.A. Uliana, R.C. Gamble, and J.D. Baldeschwieler Liposomal blockade of the reticuloendothelial system: improved tumor imaging with small unilamellar vesicles Science 220 1983 502 505
33. H. Quentmeier, J. Reinhardt, M. Zaborski, and H.G. Drexler FLT3 mutations in acute myeloid leukemia cell lines Leukemia 17 2003 120 124
34. J.L. Radomski, E.C. Hagan, H.N. Fuyat, and A.A. Nelson The pharmacology of ipecac J. Pharmacol. Exp. Ther. 104 1952 421 426
35. R. Soloman, and A.A. Gabizon Clinical pharmacology of liposomal anthracyclines: focus on pegylated liposomal Doxorubicin Clin Lymphoma Myeloma 8 2008 21 32
36. O. Tacar, P. Sriamornsak, and C.R. Dass Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems J. Pharm. Pharmacol. 65 2013 157 170
37. J. Uri Fungi pathogenic for man in antibiotic research. II. Antibiotics from Actinomycetes which are effective against fungi pathogenic for man Arzneimittelforschung 8 1958 687 692
38. E.W. van Etten, M.T. ten Kate, S.V. Snijders, and I.A. Bakker-Woudenberg Administration of liposomal agents and blood clearance capacity of the mononuclear phagocyte system Antimicrob. Agents Chemother. 42 1998 1677 1681
39. J. Wang, Y.G. Yang, M. Zhou, J.Y. Xu, Q.G. Zhang, R.F. Zhou, B. Chen, and J. Ouyang Meta-analysis of randomised clinical trials comparing idarubicin + cytarabine with daunorubicin + cytarabine as the induction chemotherapy in patients with newly diagnosed acute myeloid leukaemia PLoS ONE 8 2013 e60699
40. V. Yao, C.E. Berkman, J.K. Choi, D.S. O'Keefe, and D.J. Bacich Expression of prostate-specific membrane antigen (PSMA), increases cell folate uptake and proliferation and suggests a novel role for PSMA in the uptake of the non-polyglutamated folate, folic acid Prostate 70 2010 305 316
41. X. Zhao, H. Li, and R.J. Lee Targeted drug delivery via folate receptors Expert. Opin. Drug Deliv. 5 2008 309 319