Endurance factors improve hippocampal neurogenesis and spatial memory in mice

Learning and Memory

Volumn 18, Issue 2, 2011, Pages 103-107

  Kobilo, Tali ^a   Yuan, Chunyan ^a   Van Praag, Henriette ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFECT; ENDURANCE; FEMALE; HIPPOCAMPUS; MAZE TEST; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; SPATIAL MEMORY; TASK PERFORMANCE;

ADENYLATE KINASE; AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; FEMALE; HIPPOCAMPUS; HYPOGLYCEMIC AGENTS; IMMUNOHISTOCHEMISTRY; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; NEUROGENESIS; PHYSICAL CONDITIONING, ANIMAL; PPAR DELTA; RIBONUCLEOTIDES; SPATIAL BEHAVIOR; THIAZOLES;

EID: 79251500654     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.2001611     Document Type: Article

References (44)

1. Akerström TC, Pedersen BK. 2007. Strategies to enhance immune function for marathon runners: What can be done? Sports Med 37: 416-419.
2. Ayasolla KR, Singh AK, Singh I. 2005. 5-aminoimidazole-4-carboxamide-1- beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia. J Neuroinflammation 2: 21. doi: 10.1186/1742-2094-2-21.
3. Bronner M, Hertz R, Bar-Tana J. 2004. Kinase-independent transcriptional co-activation of peroxisome proliferator-activated receptor α by AMP-activated protein kinase. Biochem J 384: 295-305.
4. Brown JP, Couillard-Després S, Cooper-Kuhn CM, Winkler J, Aigner L, Kuhn HG. 2003. Transient expression of double-cortin during adult neurogenesis. J Comp Neurol 467: 1-10. (Pubitemid 37339753)
5. Cimini A, Cerù MP. 2008. Emerging roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of neural stem cells proliferation and differentiation. Stem Cell Rev 4: 293-303.
6. Cotman CW, Berchtold NC, Christie LA. 2007. Exercise builds brain health: Key roles of growth factor cascades and inflammation. Trends Neurosci 30: 464-472.
7. Creer DJ, Romberg C, Saksida LM, van Praag H, Bussey TJ. 2010. Running enhances spatial pattern separation in mice. Proc Natl Acad Sci 107: 2367-2372.
8. Culmsee C, Monnig J, Kemp BE, Mattson MP. 2001. AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. J Mol Neurosci 17: 45-58. (Pubitemid 32928285)
9. Dagon Y, Avraham Y, Magen I, Gertler A, Ben-Hur T, Berry EM. 2005. Nutritional status, cognition, and survival: A new role for leptin and AMP kinase. J Biol Chem 280: 42142-42148.
10. Dasgupta B, Milbrandt J. 2007. Resveratrol stimulates AMP kinase activity in neurons. Proc Natl Acad Sci 104: 7217-7222.
11. Dasgupta B, Milbrandt J. 2009. AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. Dev Cell 16: 256-270.
12. Dash PK, Orsi SA, Moore AN. 2006. Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway. J Neurosci 26: 8048-8056.
13. de la Monte SM, Tong M, Lester-Coll N, Plater M, Wands JR. 2006. Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease. J Alzheimers Dis 10: 89-109.
14. Fabel K, Fabel K, Tam B, Kaufer D, Baiker A, Simmons N, Kuo CJ, Palmer TD. 2003. VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur J Neurosci 18: 2803-2812. (Pubitemid 37542133)
15. Fan X, Ding Y, Brown S, Zhou L, Shaw M, Vella MC, Cheng H, McNay EC, Sherwin RS, McCrimmon RJ. 2009. Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes. Am J Physiol Regul Integr Comp Physiol 296: 1702-1708.
16. Fontán-Lozano A, Sáez-Cassanelli JL, Inda MC, de los Santos-Arteaga M, Sierra-Domínguez SA, López-Lluch G, Delgado-García JM, Carrión AM. 2007. Caloric restriction increases learning consolidation and facilitates synaptic plasticity through mechanisms dependent on NR2B subunits of the NMDA receptor. J Neurosci 27: 10185-10195.
17. Gobeske KT, Das S, Bonaguidi MA, Weiss C, Radulovic J, Disterhoft JF, Kessler JA. 2009. BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice. PLoS One 4: e7506. doi: 10.1371/journal. pone.0007506.
18. Gomez-Pinilla F, Vaynman S, Ying Z. 2008. Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition. Eur J Neurosci 28: 2278-2287.
19. Hall MG, Quignodon L, Desvergne B. 2008. Peroxisome proliferator- Activated receptor β/δ in the brain: Facts and hypothesis. PPAR Res 2008: 780452. doi: 10.1155/2008/780452.
20. Hardie DG. 2004. The AMP-activated protein kinase pathway - new players upstream and downstream. J Cell Sci 117: 5479-5487.
21. Higashida K, Higuchi M, Terada S. 2008. Potential role of lipin-1 in exercise-induced mitochondrial biogenesis. Biochem Biophys Res Commun 374: 587-591.
22. Hillman CH, Erickson KI, Kramer AF. 2008. Be smart, exercise your heart: Exercise effects on brain and cognition. Nat Rev Neurosci 9: 58-65.
23. Iwashita A, Muramatsu Y, Yamazaki T, Muramoto M, Kita Y, Yamazaki S, Mihara K, Moriguchi A, Matsuoka N. 2006. Neuroprotective efficacy of the peroxisome proliferator-activated receptor δ-selective agonists in vitro and in vivo. J Pharmacol Exp Ther 320: 1087-1096.
24. Jäger S, Handschin C, St-Pierre J, Spiegelman BM. 2007. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α. Proc Natl Acad Sci 104: 12017-12022.
25. Kuhn HG, Dickinson-Anson H, Gage FH. 1996. Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation. J Neurosci 15: 2027-2033.
26. Lee JH, Koh H, Kim M, Kim Y, Lee SY, Karess RE, Lee SH, Shong M, Kim JM, Kim J, et al. 2007. Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature 447: 1017-1020.
27. Marangos PJ, Loftus T, Wiesner J, Lowe T, Rossi E, Browne CE, Gruber HE. 1990. Adenosinergic modulation of homocysteine-induced seizures in mice. Epilepsia 31: 239-246.
28. McConell GK, Manimmanakorn A, Lee-Young RS, Kemp BE, Linden KC, Wadley GD. 2008. Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment. J Appl Physiol 105: 1422-1427.
29. Morris RG, Garrud P, Rawlins JN, O'Keefe J. 1982. Place navigation impaired in rats with hippocampal lesions. Nature 24: 681-683. (Pubitemid 12096189)
30. Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, et al. 2008. AMPK and PPARδ agonists are exercise mimetics. Cell 134: 405-415.
31. Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, et al. 2010. Discovery of a proneurogenic, neuroprotective chemical. Cell 142: 39-51.
32. Pold R, Jensen LS, Jessen N, Buhl ES, Schmitz O, Flyvbjerg A, Fujii N, Goodyear LJ, Gotfredsen CF, Brand CL, et al. 2005. Long-term AICAR administration and exercise prevents diabetes in ZDF rats. Diabetes 54: 928-934.
33. Potter WB, O'Riordan KJ, Barnett D, Osting SM, Wagoner M, Burger C, Roopra A. 2010. Metabolic regulation of neuronal plasticity by the energy sensor AMPK. PLoS One 5: 8996. doi: 10.1371/journal.pone.0008996.
34. Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu ZX, Dong J, Mustard KJ, Hawley SA, et al. 2007. Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metab 5: 151-156.
35. Scheff SW, Price DA. 2006. Alzheimer's disease-related alterations in synaptic density: Neocortex and hippocampus. J Alzheimers Dis 9: 101-115.
36. Steinberg GR, Kemp BE. 2009. AMPK in Health and Disease. Physiol Rev 89: 1025-1078.
37. Suwa M, Nakano H, Radak Z, Kumagai S. 2010. Short-term adenosine monophosphate-activated protein kinase activator 5-aminoimidazole-4-carboxamide- 1-β-d-ribofuranoside treatment increases the sirtuin 1 protein expression in skeletal muscle. Metabolism. doi: 10.1016/j.metabol.2010.03.003.
38. Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, et al. 2003. Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci 100: 15924-15929.
39. Trejo JL, Carro E, Torres-Aleman I. 2001. Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. J Neurosci 21: 1628-1634.
40. van Praag H. 2008. Neurogenesis and exercise: Past and future directions. Neuromolecular Med 10: 128-140.
41. van Praag H, Christie BR, Sejnowski TJ, Gage FH. 1999. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci 96: 13427-13431.
42. Wang YX, Zhang CL, Yu RT, Cho HK, Nelson MC, Bayuga-Ocampo CR, Ham J, Kang H, Evans RM. 2004. Regulation of muscle fiber type and running endurance by PPARδ. PLoS Biol 2: e294. doi: 10.1371/journal.pbio.0020294.
43. Winder WW, Hardie DG. 1996. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am J Physiol Endocrinol Metab 270: E299-E304. (Pubitemid 126756199)
44. Wojtaszewski JF, Nielsen P, Hansen BF, Richter EA, Kiens BJ. 2000. Isoform-specific and exercise intensity-dependent activation of 5′-AMP-activated protein kinase in human skeletal muscle. J Physiol 528: 221-226.