메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

Identification and HLA-tetramer-validation of human CD4+and CD8+ T cell responses against HCMV proteins IE1 and IE2

Author keywords

[No Author keywords available]

Indexed keywords

CYTOMEGALOVIRUS ANTIGEN PP65; GAMMA INTERFERON; IMMEDIATE EARLY PROTEIN; IMMEDIATE EARLY PROTEIN 1; IMMEDIATE EARLY PROTEIN 2; TETRAMER; UNCLASSIFIED DRUG; EPITOPE; IE1 PROTEIN, CYTOMEGALOVIRUS; IE2 PROTEIN, CYTOMEGALOVIRUS; TRANSACTIVATOR PROTEIN;

EID: 84899733929     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094892     Document Type: Article
Times cited : (22)

References (79)
  • 1
    • 77954170594 scopus 로고    scopus 로고
    • Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection
    • Cannon MJ, Schmid DS, Hyde TB (2010) Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection. Rev Med Virol 20: 202-213.
    • (2010) Rev Med Virol , vol.20 , pp. 202-213
    • Cannon, M.J.1    Schmid, D.S.2    Hyde, T.B.3
  • 3
    • 1542373665 scopus 로고    scopus 로고
    • The impact of cytomegalovirus serostatus of donor and recipient before hematopoietic stem cell transplantation in the era of antiviral prophylaxis and preemptive therapy
    • DOI 10.1182/blood-2003-10-3616
    • Boeckh M, Nichols WG (2004) The impact of cytomegalovirus serostatus of donor and recipient before hematopoietic stem cell transplantation in the era of antiviral prophylaxis and preemptive therapy. Blood 103: 2003-2008. (Pubitemid 38326213)
    • (2004) Blood , vol.103 , Issue.6 , pp. 2003-2008
    • Boeckh, M.1    Nichols, W.G.2
  • 5
    • 0035141424 scopus 로고    scopus 로고
    • Investigation of CMV disease in immunocompromised patients
    • Emery VC (2001) Investigation of CMV disease in immunocompromised patients. J Clin Pathol 54: 84-88.
    • (2001) J Clin Pathol , vol.54 , pp. 84-88
    • Emery, V.C.1
  • 6
    • 34547804165 scopus 로고    scopus 로고
    • Cytomegalovirus Infection after Allogeneic Transplantation: Comparison of Cord Blood with Peripheral Blood and Marrow Graft Sources
    • DOI 10.1016/j.bbmt.2007.06.006, PII S1083879107003187
    • Walker CM, van Burik JA, De For TE, Weisdorf DJ (2007) Cytomegalovirus infection after allogeneic transplantation: comparison of cord blood with peripheral blood and marrow graft sources. Biol Blood Marrow Transplant 13: 1106-1115. (Pubitemid 47240751)
    • (2007) Biology of Blood and Marrow Transplantation , vol.13 , Issue.9 , pp. 1106-1115
    • Walker, C.M.1    Van Burik, J.-A.H.2    De For, T.E.3    Weisdorf, D.J.4
  • 8
    • 79954991007 scopus 로고    scopus 로고
    • Is HCMV a tumor promoter?
    • Soroceanu L, Cobbs CS (2011) Is HCMV a tumor promoter? Virus Res 157: 193-203.
    • (2011) Virus Res , vol.157 , pp. 193-203
    • Soroceanu, L.1    Cobbs, C.S.2
  • 9
    • 84891359962 scopus 로고    scopus 로고
    • Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: Implications for a role in gliomagenesis
    • Khan Z, Yaiw KC, Wilhelmi V, Lam H, Rahbar A, et al. (2014) Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: implications for a role in gliomagenesis. Carcinogenesis 35: 145-154.
    • (2014) Carcinogenesis , vol.35 , pp. 145-154
    • Khan, Z.1    Yaiw, K.C.2    Wilhelmi, V.3    Lam, H.4    Rahbar, A.5
  • 10
    • 84883439743 scopus 로고    scopus 로고
    • Survival in patients with glioblastoma receiving valganciclovir
    • Soderberg-Naucler C, Rahbar A, Stragliotto G (2013) Survival in patients with glioblastoma receiving valganciclovir. N Engl J Med 369: 985-986.
    • (2013) N Engl J Med , vol.369 , pp. 985-986
    • Soderberg-Naucler, C.1    Rahbar, A.2    Stragliotto, G.3
  • 11
    • 84866625471 scopus 로고    scopus 로고
    • Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation
    • Griffiths PD (2012) Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation. Lancet Infect Dis 12: 790-798.
    • (2012) Lancet Infect Dis , vol.12 , pp. 790-798
    • Griffiths, P.D.1
  • 12
    • 0034878967 scopus 로고    scopus 로고
    • Cytomegalovirus treatment options in immunocompromised patients
    • DOI 10.1517/14656566.2.8.1247
    • Khare MD, Sharland M (2001) Cytomegalovirus treatment options in immunocompromised patients. Expert Opin Pharmacother 2: 1247-1257. (Pubitemid 32750363)
    • (2001) Expert Opinion on Pharmacotherapy , vol.2 , Issue.8 , pp. 1247-1257
    • Khare, M.D.1    Sharland, M.2
  • 13
    • 0025995695 scopus 로고
    • Cytotoxic Tlymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: Pattern of recovery and correlation with cytomegalovirus infection and disease
    • Reusser P, Riddell SR, Meyers JD, Greenberg PD (1991) Cytotoxic Tlymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease. Blood 78: 1373-1380.
    • (1991) Blood , vol.78 , pp. 1373-1380
    • Reusser, P.1    Riddell, S.R.2    Meyers, J.D.3    Greenberg, P.D.4
  • 14
    • 33747203211 scopus 로고    scopus 로고
    • + T-cell reconstitution in young recipients of allogeneic hematopoietic stem cell transplants
    • DOI 10.1182/blood-2005-11-012864
    • Lilleri D, Gerna G, Fornara C, Lozza L, Maccario R, et al. (2006) Prospective simultaneous quantification of human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in young recipients of allogeneic hematopoietic stem cell transplants. Blood 108: 1406-1412. (Pubitemid 44232045)
    • (2006) Blood , vol.108 , Issue.4 , pp. 1406-1412
    • Lilleri, D.1    Gerna, G.2    Fornara, C.3    Lozza, L.4    Maccario, R.5    Locatelli, F.6
  • 16
    • 77952714684 scopus 로고    scopus 로고
    • Immunotherapy and vaccination after transplant: The present, the future
    • Emery VC, Einsele H, Atabani S, Haque T (2010) Immunotherapy and vaccination after transplant: the present, the future. Infect Dis Clin North Am 24: 515-529.
    • (2010) Infect Dis Clin North Am , vol.24 , pp. 515-529
    • Emery, V.C.1    Einsele, H.2    Atabani, S.3    Haque, T.4
  • 17
    • 84865324427 scopus 로고    scopus 로고
    • Therapeutic strategies for the prevention and treatment of cytomegalovirus infection
    • Sellar RS, Peggs KS (2012) Therapeutic strategies for the prevention and treatment of cytomegalovirus infection. Expert Opin Biol Ther 12: 1161-1172.
    • (2012) Expert Opin Biol Ther , vol.12 , pp. 1161-1172
    • Sellar, R.S.1    Peggs, K.S.2
  • 21
    • 0642308424 scopus 로고    scopus 로고
    • Reconstitution of T-cell repertoire after autologous stem cell transplantation: Influence of CD34 selection and cytomegalovirus infection
    • Peggs KS, Verfuerth S, Pizzey A, Khan N, Moss P, et al. (2003) Reconstitution of T-cell repertoire after autologous stem cell transplantation: influence of CD34 selection and cytomegalovirus infection. Biol Blood Marrow Transplant 9: 198-205.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 198-205
    • Peggs, K.S.1    Verfuerth, S.2    Pizzey, A.3    Khan, N.4    Moss, P.5
  • 22
    • 84884178203 scopus 로고    scopus 로고
    • Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation
    • Leen AM, Bollard CM, Mendizabal AM, Shpall EJ, Szabolcs P, et al. (2013) Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation. Blood 121: 5113-5123.
    • (2013) Blood , vol.121 , pp. 5113-5123
    • Leen, A.M.1    Bollard, C.M.2    Mendizabal, A.M.3    Shpall, E.J.4    Szabolcs, P.5
  • 23
    • 79952470341 scopus 로고    scopus 로고
    • Adoptive transfer and selective reconstitution of streptamer-selected cytomegalovirusspecific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation
    • Schmitt A, Tonn T, Busch DH, Grigoleit GU, Einsele H, et al. (2011) Adoptive transfer and selective reconstitution of streptamer-selected cytomegalovirusspecific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation. Transfusion 51: 591-599.
    • (2011) Transfusion , vol.51 , pp. 591-599
    • Schmitt, A.1    Tonn, T.2    Busch, D.H.3    Grigoleit, G.U.4    Einsele, H.5
  • 24
    • 84867859374 scopus 로고    scopus 로고
    • Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection
    • Ebert S, Podlech J, Gillert-Marien D, Gergely KM, Buttner JK, et al. (2012) Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection. Med Microbiol Immunol 201: 527-539.
    • (2012) Med Microbiol Immunol , vol.201 , pp. 527-539
    • Ebert, S.1    Podlech, J.2    Gillert-Marien, D.3    Gergely, K.M.4    Buttner, J.K.5
  • 25
    • 0030266708 scopus 로고    scopus 로고
    • Exhaustion of CTL Memory and Recrudescence of Viremia in Lymphocytic Choriomeningitis Virus-Infected MHC Class II-Deficient Mice and B Cell-Deficient Mice
    • Thomsen AR, Johansen J, Marker O, Christensen JP (1996) Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virusinfected MHC class II-deficient mice and B cell-deficient mice. J Immunol 157: 3074-3080. (Pubitemid 126450067)
    • (1996) Journal of Immunology , vol.157 , Issue.7 , pp. 3074-3080
    • Thomsen, A.R.1    Johansen, J.2    Marker, O.3    Christensen, J.P.4
  • 26
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • DOI 10.1126/science.1083317
    • Sun JC, Bevan MJ (2003) Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300: 339-342. (Pubitemid 36433727)
    • (2003) Science , vol.300 , Issue.5617 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 27
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
    • Walter EA, Greenberg PD, Gilbert MJ, Finch RJ, Watanabe KS, et al. (1995) Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl J Med 333: 1038-1044.
    • (1995) N Engl J Med , vol.333 , pp. 1038-1044
    • Walter, E.A.1    Greenberg, P.D.2    Gilbert, M.J.3    Finch, R.J.4    Watanabe, K.S.5
  • 28
    • 0026648439 scopus 로고
    • Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones
    • Riddell SR, Watanabe KS, Goodrich JM, Li CR, Agha ME, et al. (1992) Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science 257: 238-241.
    • (1992) Science , vol.257 , pp. 238-241
    • Riddell, S.R.1    Watanabe, K.S.2    Goodrich, J.M.3    Li, C.R.4    Agha, M.E.5
  • 29
    • 34447336109 scopus 로고    scopus 로고
    • - phenotype parallels loss of proliferative capacity and precedes progression to HIV-related CMV end-organ disease
    • DOI 10.1016/j.clim.2007.04.016, PII S1521661607012065
    • Bronke C, Jansen CA, Westerlaken GH, De Cuyper IM, Miedema F, et al. (2007) Shift of CMV-specific CD4+ T-cells to the highly differentiated CD45RO-CD27- phenotype parallels loss of proliferative capacity and precedes progression to HIV-related CMV end-organ disease. Clin Immunol 124: 190-199. (Pubitemid 47059042)
    • (2007) Clinical Immunology , vol.124 , Issue.2 , pp. 190-199
    • Bronke, C.1    Jansen, C.A.2    Westerlaken, G.H.A.3    De Cuyper, I.M.4    Miedema, F.5    Tesselaar, K.6    Van Baarle, D.7
  • 30
    • 84869430607 scopus 로고    scopus 로고
    • Moving Successful Virus-specific T-cell Therapy for Hematopoietic Stem Cell Recipients to Late Phase Clinical Trials
    • Rooney C, Leen A (2012) Moving Successful Virus-specific T-cell Therapy for Hematopoietic Stem Cell Recipients to Late Phase Clinical Trials. Mol Ther Nucleic Acids 1: e55.
    • (2012) Mol Ther Nucleic Acids , vol.1
    • Rooney, C.1    Leen, A.2
  • 32
    • 0035860626 scopus 로고    scopus 로고
    • Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines
    • DOI 10.1016/S0264-410X(01)00233-X, PII S0264410X0100233X
    • Livingston BD, Newman M, Crimi C, McKinney D, Chesnut R, et al. (2001) Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines. Vaccine 19: 4652-4660. (Pubitemid 32800747)
    • (2001) Vaccine , vol.19 , Issue.32 , pp. 4652-4660
    • Livingston, B.D.1    Newman, M.2    Crimi, C.3    McKinney, D.4    Chesnut, R.5    Sette, A.6
  • 33
    • 0035697665 scopus 로고    scopus 로고
    • The development of multi-epitope vaccines: Epitope identification, vaccine design and clinical evaluation
    • DOI 10.1006/biol.2001.0297
    • Sette A, Livingston B, McKinney D, Appella E, Fikes J, et al. (2001) The development of multi-epitope vaccines: epitope identification, vaccine design and clinical evaluation. Biologicals 29: 271-276. (Pubitemid 34093652)
    • (2001) Biologicals , vol.29 , Issue.3-4 , pp. 271-276
    • Sette, A.1    Livingston, B.2    McKinney, D.3    Appella, E.4    Fikes, J.5    Sidney, J.6    Newman, M.7    Chesnut, R.8
  • 34
    • 84929277851 scopus 로고    scopus 로고
    • Immediate-early viral gene regulation and function
    • Arvin A, Campadelli-Fiume G, Mocarski E, Moore PS, Roizman B et al., editors. Cambridge: Cambridge University Press 2007
    • Stinski MF, Meier JL (2007) Immediate-early viral gene regulation and function. In: Arvin A, Campadelli-Fiume G, Mocarski E, Moore PS, Roizman B et al., editors.Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press 2007.
    • (2007) Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis
    • Stinski, M.F.1    Meier, J.L.2
  • 36
    • 0035132107 scopus 로고    scopus 로고
    • Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes
    • DOI 10.1128/JVI.75.4.1870-1878.2001
    • Marchini A, Liu H, Zhu H (2001) Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes. J Virol 75: 1870-1878. (Pubitemid 32110177)
    • (2001) Journal of Virology , vol.75 , Issue.4 , pp. 1870-1878
    • Marchini, A.1    Liu, H.2    Zhu, H.3
  • 37
    • 0031985313 scopus 로고    scopus 로고
    • Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant
    • Greaves RF, Mocarski ES (1998) Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant. J Virol 72: 366-379. (Pubitemid 28048848)
    • (1998) Journal of Virology , vol.72 , Issue.1 , pp. 366-379
    • Greaves, R.F.1    Mocarski, E.S.2
  • 39
    • 11344288398 scopus 로고    scopus 로고
    • Enumerating antigen-specific t-cell responses in peripheral blood: A comparison of peptide MHC tetramer, ELISpot, and intracellular cytokine analysis
    • Hobeika AC, Morse MA, Osada T, Ghanayem M, Niedzwiecki D, et al. (2005) Enumerating antigen-specific T-cell responses in peripheral blood: a comparison of peptide MHC Tetramer, ELISpot, and intracellular cytokine analysis. J Immunother 28: 63-72. (Pubitemid 40075939)
    • (2005) Journal of Immunotherapy , vol.28 , Issue.1 , pp. 63-72
    • Hobeika, A.C.1    Morse, M.A.2    Osada, T.3    Ghanayem, M.4    Niedzwiecki, D.5    Barrier, R.6    Lyerly, H.K.7    Clay, T.M.8
  • 41
    • 84899756943 scopus 로고    scopus 로고
    • MHC class II tetramers made from isolated recombinant alpha and beta chains refolded with affinity-tagged peptides
    • Braendstrup P, Justesen S, Osterbye T, Nielsen LL, Mallone R, et al. (2013) MHC class II tetramers made from isolated recombinant alpha and beta chains refolded with affinity-tagged peptides. PLoS One 8: e73648.
    • (2013) PLoS One , vol.8
    • Braendstrup, P.1    Justesen, S.2    Osterbye, T.3    Nielsen, L.L.4    Mallone, R.5
  • 42
    • 78651260398 scopus 로고    scopus 로고
    • HLArestrictor - A tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides
    • Erup Larsen M, Kloverpris H, Stryhn A, Koofhethile CK, Sims S, et al. (2011) HLArestrictor - a tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides. Immunogenetics 63: 43-55.
    • (2011) Immunogenetics , vol.63 , pp. 43-55
    • Erup Larsen, M.1    Kloverpris, H.2    Stryhn, A.3    Koofhethile, C.K.4    Sims, S.5
  • 43
    • 78149354807 scopus 로고    scopus 로고
    • NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure
    • Nielsen M, Justesen S, Lund O, Lundegaard C, Buus S (2010) NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure. Immunome Res 6: 9.
    • (2010) Immunome Res , vol.6 , pp. 9
    • Nielsen, M.1    Justesen, S.2    Lund, O.3    Lundegaard, C.4    Buus, S.5
  • 44
    • 61849124792 scopus 로고    scopus 로고
    • Peptide binding to HLA class I molecules: Homogenous, high-throughput screening, and affinity assays
    • Harndahl M, Justesen S, Lamberth K, Roder G, Nielsen M, et al. (2009) Peptide binding to HLA class I molecules: homogenous, high-throughput screening, and affinity assays. J Biomol Screen 14: 173-180.
    • (2009) J Biomol Screen , vol.14 , pp. 173-180
    • Harndahl, M.1    Justesen, S.2    Lamberth, K.3    Roder, G.4    Nielsen, M.5
  • 45
    • 66849119253 scopus 로고    scopus 로고
    • Functional recombinant MHC class II molecules and high-throughput peptide-binding assays
    • Justesen S, Harndahl M, Lamberth K, Nielsen LL, Buus S (2009) Functional recombinant MHC class II molecules and high-throughput peptide-binding assays. Immunome Res 5: 2.
    • (2009) Immunome Res , vol.5 , pp. 2
    • Justesen, S.1    Harndahl, M.2    Lamberth, K.3    Nielsen, L.L.4    Buus, S.5
  • 46
    • 81255157073 scopus 로고    scopus 로고
    • Real-time, highthroughput measurements of peptide-MHC-I dissociation using a scintillation proximity assay
    • Harndahl M, Rasmussen M, Roder G, Buus S (2011) Real-time, highthroughput measurements of peptide-MHC-I dissociation using a scintillation proximity assay. J Immunol Methods 374: 5-12.
    • (2011) J Immunol Methods , vol.374 , pp. 5-12
    • Harndahl, M.1    Rasmussen, M.2    Roder, G.3    Buus, S.4
  • 48
    • 70349972137 scopus 로고    scopus 로고
    • Estimation of high-resolution HLA-A, -B, -C, -DRB1 allele and haplotype frequencies based on 8862 German stem cell donors and implications for strategic donor registry planning
    • Schmidt AH, Baier D, Solloch UV, Stahr A, Cereb N, et al. (2009) Estimation of high-resolution HLA-A, -B, -C, -DRB1 allele and haplotype frequencies based on 8862 German stem cell donors and implications for strategic donor registry planning. Hum Immunol 70: 895-902.
    • (2009) Hum Immunol , vol.70 , pp. 895-902
    • Schmidt, A.H.1    Baier, D.2    Solloch, U.V.3    Stahr, A.4    Cereb, N.5
  • 49
    • 84857822895 scopus 로고    scopus 로고
    • MHC class II tetramers
    • Nepom GT (2012) MHC class II tetramers. J Immunol 188: 2477-2482.
    • (2012) J Immunol , vol.188 , pp. 2477-2482
    • Nepom, G.T.1
  • 50
    • 0023257028 scopus 로고
    • Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells
    • DOI 10.1038/328395a0
    • Sette A, Buus S, Colon S, Smith JA, Miles C, et al. (1987) Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. Nature 328: 395-399. (Pubitemid 17097771)
    • (1987) Nature , vol.328 , Issue.6129 , pp. 395-399
    • Sette, A.1    Buus, S.2    Colon, S.3
  • 51
    • 84862152481 scopus 로고    scopus 로고
    • Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity
    • Harndahl M, Rasmussen M, Roder G, Dalgaard Pedersen I, Sorensen M, et al. (2012) Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity. Eur J Immunol 42: 1405-1416.
    • (2012) Eur J Immunol , vol.42 , pp. 1405-1416
    • Harndahl, M.1    Rasmussen, M.2    Roder, G.3    Dalgaard Pedersen, I.4    Sorensen, M.5
  • 52
    • 33947696311 scopus 로고    scopus 로고
    • T cell recognition patterns of immunodominant cytomegalovirus antigens in primary and persistent infection
    • Khan N, Best D, Bruton R, Nayak L, Rickinson AB, et al. (2007) T cell recognition patterns of immunodominant cytomegalovirus antigens in primary and persistent infection. J Immunol 178: 4455-4465. (Pubitemid 46492397)
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4455-4465
    • Khan, N.1    Best, D.2    Bruton, R.3    Nayak, L.4    Rickinson, A.B.5    Moss, P.A.H.6
  • 53
    • 16644387582 scopus 로고    scopus 로고
    • Major contribution of codominant CD8 and CD4 T cell epitopes to the human cytomegalovirus-specific T cell repertoire
    • DOI 10.1007/s00018-004-4363-x
    • Nastke MD, Herrgen L, Walter S, Wernet D, Rammensee HG, et al. (2005) Major contribution of codominant CD8 and CD4 T cell epitopes to the human cytomegalovirus-specific T cell repertoire. Cell Mol Life Sci 62: 77-86. (Pubitemid 40933094)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.1 , pp. 77-86
    • Nastke, M.-D.1    Herrgen, L.2    Walter, S.3    Wernet, D.4    Rammensee, H.-G.5    Stevanovic, S.6
  • 54
    • 0345373932 scopus 로고    scopus 로고
    • +-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers
    • DOI 10.1128/JVI.77.9.5226-5240.2003
    • Elkington R, Walker S, Crough T, Menzies M, Tellam J, et al. (2003) Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers. J Virol 77: 5226-5240. (Pubitemid 36460937)
    • (2003) Journal of Virology , vol.77 , Issue.9 , pp. 5226-5240
    • Elkington, R.1    Walker, S.2    Crough, T.3    Menzies, M.4    Tellam, J.5    Bharadwaj, M.6    Khanna, R.7
  • 57
    • 48249089602 scopus 로고    scopus 로고
    • Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring
    • Kirchner A, Hoffmeister B, Cherepnev GG, Fuhrmann S, Streitz M, et al. (2008) Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring. J Med Virol 80: 1604-1614.
    • (2008) J Med Virol , vol.80 , pp. 1604-1614
    • Kirchner, A.1    Hoffmeister, B.2    Cherepnev, G.G.3    Fuhrmann, S.4    Streitz, M.5
  • 59
    • 0037090155 scopus 로고    scopus 로고
    • + T cell responses against human cytomegalovirus proteins pp65 and immediate early 1 shows similarities in precursor frequency, oligoclonality, and phenotype
    • DOI 10.1086/339963
    • Khan N, Cobbold M, Keenan R, Moss PA (2002) Comparative analysis of CD8+ T cell responses against human cytomegalovirus proteins pp65 and immediate early 1 shows similarities in precursor frequency, oligoclonality, and phenotype. J Infect Dis 185: 1025-1034. (Pubitemid 34297759)
    • (2002) Journal of Infectious Diseases , vol.185 , Issue.8 , pp. 1025-1034
    • Khan, N.1    Cobbold, M.2    Keenan, R.3    Moss, P.A.H.4
  • 60
    • 0036063654 scopus 로고    scopus 로고
    • Identification of a conserved HLA-A2-restricted decapeptide from the IE1 protein (pUL123) of human cytomegalovirus
    • DOI 10.1006/viro.2001.1335
    • Frankenberg N, Pepperl-Klindworth S, Meyer RG, Plachter B (2002) Identification of a conserved HLA-A2-restricted decapeptide from the IE1 protein (pUL123) of human cytomegalovirus. Virology 295: 208-216. (Pubitemid 34921306)
    • (2002) Virology , vol.295 , Issue.2 , pp. 208-216
    • Frankenberg, N.1    Pepperl-Klindworth, S.2    Meyer, R.G.3    Plachter, B.4
  • 61
    • 84878474103 scopus 로고    scopus 로고
    • Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion
    • Ameres S, Mautner J, Schlott F, Neuenhahn M, Busch DH, et al. (2013) Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion. PLoS Pathog 9: e1003383.
    • (2013) PLoS Pathog , vol.9
    • Ameres, S.1    Mautner, J.2    Schlott, F.3    Neuenhahn, M.4    Busch, D.H.5
  • 62
    • 0026047830 scopus 로고
    • Fine specificity of cellular immune responses in humans to human cytomegalovirus immediate-early 1 protein
    • Alp NJ, Allport TD, Van Zanten J, Rodgers B, Sissons JG, et al. (1991) Fine specificity of cellular immune responses in humans to human cytomegalovirus immediate-early 1 protein. J Virol 65: 4812-4820.
    • (1991) J Virol , vol.65 , pp. 4812-4820
    • Alp, N.J.1    Allport, T.D.2    Van Zanten, J.3    Rodgers, B.4    Sissons, J.G.5
  • 63
  • 65
    • 0024796883 scopus 로고
    • Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class II and promiscuous recognition by T cells
    • DOI 10.1002/eji.1830191209
    • Panina-Bordignon P, Tan A, Termijtelen A, Demotz S, Corradin G, et al. (1989) Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur J Immunol 19: 2237-2242. (Pubitemid 20024747)
    • (1989) European Journal of Immunology , vol.19 , Issue.12 , pp. 2237-2242
    • Panina-Bordignon, P.1    Tan, A.2    Termijtelen, A.3    Demotz, S.4    Corradin, G.5    Lanzavecchia, A.6
  • 66
    • 2942730105 scopus 로고    scopus 로고
    • Detection and characterization of cellular immune responses using peptide-MHC microarrays
    • Soen Y, Chen DS, Kraft DL, Davis MM, Brown PO (2003) Detection and characterization of cellular immune responses using peptide-MHC microarrays. PLoS Biol 1: E65.
    • (2003) PLoS Biol , vol.1
    • Soen, Y.1    Chen, D.S.2    Kraft, D.L.3    Davis, M.M.4    Brown, P.O.5
  • 68
    • 77955326476 scopus 로고    scopus 로고
    • Peptide-MHC cellular microarray with innovative data analysis system for simultaneously detecting multiple CD4 T-cell responses
    • Ge X, Gebe JA, Bollyky PL, James EA, Yang J, et al. (2010) Peptide-MHC cellular microarray with innovative data analysis system for simultaneously detecting multiple CD4 T-cell responses. PLoS One 5: e11355.
    • (2010) PLoS One , vol.5
    • Ge, X.1    Gebe, J.A.2    Bollyky, P.L.3    James, E.A.4    Yang, J.5
  • 69
    • 77955512026 scopus 로고    scopus 로고
    • Peptide microarrays for the profiling of cytotoxic T-lymphocyte activity using minimum numbers of cells
    • Hoff A, Bagu AC, Andre T, Roth G, Wiesmuller KH, et al. (2010) Peptide microarrays for the profiling of cytotoxic T-lymphocyte activity using minimum numbers of cells. Cancer Immunol Immunother 59: 1379-1387.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 1379-1387
    • Hoff, A.1    Bagu, A.C.2    Andre, T.3    Roth, G.4    Wiesmuller, K.H.5
  • 70
    • 84870659704 scopus 로고    scopus 로고
    • Highresolution mapping of linear antibody epitopes using ultrahigh-density peptide microarrays
    • Buus S, Rockberg J, Forsstrom B, Nilsson P, Uhlen M, et al. (2012) Highresolution mapping of linear antibody epitopes using ultrahigh-density peptide microarrays. Mol Cell Proteomics 11: 1790-1800.
    • (2012) Mol Cell Proteomics , vol.11 , pp. 1790-1800
    • Buus, S.1    Rockberg, J.2    Forsstrom, B.3    Nilsson, P.4    Uhlen, M.5
  • 72
    • 83155164579 scopus 로고    scopus 로고
    • Predictions versus high-throughput experiments in T-cell epitope discovery: Competition or synergy?
    • Lundegaard C, Lund O, Nielsen M (2012) Predictions versus high-throughput experiments in T-cell epitope discovery: competition or synergy? Expert Rev Vaccines 11: 43-54.
    • (2012) Expert Rev Vaccines , vol.11 , pp. 43-54
    • Lundegaard, C.1    Lund, O.2    Nielsen, M.3
  • 73
    • 83155180577 scopus 로고    scopus 로고
    • Toward more accurate panspecific MHC-peptide binding prediction: A review of current methods and tools
    • Zhang L, Udaka K, Mamitsuka H, Zhu S (2012) Toward more accurate panspecific MHC-peptide binding prediction: a review of current methods and tools. Brief Bioinform 13: 350-364.
    • (2012) Brief Bioinform , vol.13 , pp. 350-364
    • Zhang, L.1    Udaka, K.2    Mamitsuka, H.3    Zhu, S.4
  • 74
    • 38649128150 scopus 로고    scopus 로고
    • Class II major histocompatibility complex tetramer staining: Progress, problems, and prospects
    • DOI 10.1111/j.1365-2567.2007.02801.x
    • Vollers SS, Stern LJ (2008) Class II major histocompatibility complex tetramer staining: progress, problems, and prospects. Immunology 123: 305-313. (Pubitemid 351171199)
    • (2008) Immunology , vol.123 , Issue.3 , pp. 305-313
    • Vollers, S.S.1    Stern, L.J.2
  • 76
    • 84879023453 scopus 로고    scopus 로고
    • A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population
    • McKinney DM, Southwood S, Hinz D, Oseroff C, Arlehamn CS, et al. (2013) A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population. Immunogenetics 65: 357-370.
    • (2013) Immunogenetics , vol.65 , pp. 357-370
    • McKinney, D.M.1    Southwood, S.2    Hinz, D.3    Oseroff, C.4    Arlehamn, C.S.5
  • 77
    • 15844410585 scopus 로고    scopus 로고
    • Ex vivo expansion of human cytomegalovirus-specific cytotoxic T cells by recombinant polyepitope: Implications for HCMV immunotherapy
    • DOI 10.1002/eji.200425746
    • Rist M, Cooper L, Elkington R, Walker S, Fazou C, et al. (2005) Ex vivo expansion of human cytomegalovirus-specific cytotoxic T cells by recombinant polyepitope: implications for HCMV immunotherapy. Eur J Immunol 35: 996-1007. (Pubitemid 40425556)
    • (2005) European Journal of Immunology , vol.35 , Issue.3 , pp. 996-1007
    • Rist, M.1    Cooper, L.2    Elkington, R.3    Walker, S.4    Fazou, C.5    Tellam, J.6    Crough, T.7    Khanna, R.8
  • 79
    • 50449086291 scopus 로고    scopus 로고
    • A novel approach to evaluate the immunogenicity of viral antigens of clinical importance in HLA transgenic murine models
    • Krishnan A, Wang Z, Srivastava T, Rawal R, Manchanda P, et al. (2008) A novel approach to evaluate the immunogenicity of viral antigens of clinical importance in HLA transgenic murine models. Immunol Lett 120: 108-116.
    • (2008) Immunol Lett , vol.120 , pp. 108-116
    • Krishnan, A.1    Wang, Z.2    Srivastava, T.3    Rawal, R.4    Manchanda, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.