Shift of CMV-specific CD4+ T-cells to the highly differentiated CD45RO-CD27- phenotype parallels loss of proliferative capacity and precedes progression to HIV-related CMV end-organ disease

Clinical Immunology

Volumn 124, Issue 2, 2007, Pages 190-199

  Bronke, Corine ^a   Jansen, Christine A ^a   Westerlaken, Geertje H A ^a   De Cuyper, Iris M ^a   Miedema, Frank ^a   Tesselaar, Kiki ^a   van Baarle, Debbie ^a  

^a SANQUIN RESEARCH   (Netherlands)

Author keywords

CD4; CMV; Cytokines; HIV 1; Phenotype; Proliferation

Indexed keywords

CD27 ANTIGEN; CD45RO ANTIGEN; CYTOMEGALOVIRUS ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 2;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; OPPORTUNISTIC INFECTION; PHENOTYPE; PRIORITY JOURNAL;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIGENS, CD27; ANTIGENS, CD45; CD4-POSITIVE T-LYMPHOCYTES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DISEASE PROGRESSION; HIV INFECTIONS; HIV-1; HUMANS; INTERFERON TYPE II; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION;

EID: 34447336109     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2007.04.016     Document Type: Article

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