The association between personal sun exposure, serum vitamin D and global methylation in human lymphocytes in a population of healthy adults in South Australia

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 765, Issue , 2014, Pages 6-10

  Nair Shalliker, Visalini ^a   Dhillon, Varinderpal ^b   Clements, Mark ^c   Armstrong, Bruce K ^d   Fenech, Michael ^b  

^a CANCER RESEARCH DIVISION   (Australia)

^b CSIRO   (Australia)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

DNA damage; Global methylation; LINE 1 repetitive elements; Solar UV exposure; Vitamin D

Indexed keywords

VITAMIN D; CALCIFEDIOL;

ADULT; ANAPHASE; APOPTOSIS; ARTICLE; AUSTRALIA; BLOOD SAMPLING; CELL DEATH; CONTROLLED STUDY; CYTOKINESIS; DNA METHYLATION; DNA SEQUENCE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LYMPHOCYTE; MALE; MICRONUCLEUS; PRIORITY JOURNAL; PYROSEQUENCING; SUN EXPOSURE; TRANSPOSON; BLOOD; CLINICAL TRIAL; LONG INTERSPERSED REPEAT; METABOLISM; MIDDLE AGED; RADIATION RESPONSE; SUNLIGHT; ULTRAVIOLET RADIATION;

ADULT; AUSTRALIA; CALCIFEDIOL; DNA METHYLATION; FEMALE; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; LYMPHOCYTES; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MIDDLE AGED; SUNLIGHT; ULTRAVIOLET RAYS;

EID: 84899718432     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2014.04.001     Document Type: Article

References (38)

1. Nair-Shalliker V., Fenech M., Forder P.M., Clements M.S., Armstrong B.K. Sunlight and vitamin D affect DNA damage, cell division and cell death in human lymphocytes: a cross-sectional study in South Australia. Mutagenesis 2012, 27:609-614.
2. Capper R., Britt-Compton B., Tankimanova M., Rowson J., Letsolo B., Man S., Haughton M., Baird D.M. The nature of telomere fusion and a definition of the critical telomere length in human cells. Genes Dev. 2007, 21:2495-2508.
3. Fenech M., Kirsch-Volders M., Natarajan A.T., Surralles J., Crott J.W., Parry J., Norppa H., Eastmond D.A., Tucker J.D., Thomas P. Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells. Mutagenesis 2011, 26:125-132.
4. Rao X., Zhang Y., Yi Q., Hou H., Xu B., Chu L., Huang Y., Zhang W., Fenech M., Shi Q. Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat. Res. 2008, 646:41-49.
5. Thomas P., Umegaki K., Fenech M. Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay. Mutagenesis 2003, 18:187-194.
6. Bentham G., Wolfreys A.M., Liu Y., Cortopassi G., Green M.H., Arlett C.F., Cole J. Frequencies of hprt(-) mutations and bcl-2 translocations in circulating human lymphocytes are correlated with United Kingdom sunlight records. Mutagenesis 1999, 14:527-532.
7. Cox A.G., Hampton M.B. Bcl-2 over-expression promotes genomic instability by inhibiting apoptosis of cells exposed to hydrogen peroxide. Carcinogenesis 2007, 28:2166-2171.
8. Martinez J.G., Perez-Escuredo J., Castro-Santos P., Marcos C.A., Pendas J.L., Fraga M.F., Hermsen M.A. Hypomethylation of LINE-1, and not centromeric SAT-alpha, is associated with centromeric instability in head and neck squamous cell carcinoma. Cell Oncol. (Dordr.) 2012, 35:259-267.
9. Belgnaoui S.M., Gosden R.G., Semmes O.J., Haoudi A. Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells. Cancer Cell Int. 2006, 6:13.
10. St L.G., Hammell N., McCaffrey T.A. A LINE-1 component to human aging: do LINE elements exact a longevity cost for evolutionary advantage?. Mech. Ageing Dev. 2010, 131:299-305.
11. Bonassi S., Coskun E., Ceppi M., Lando C., Bolognesi C., Burgaz S., Holland N., Kirsh-Volders M., Knasmueller S., Zeiger E., Carnesoltas D., Cavallo D., da S.J., de A.V., Demircigil G.C., Dominguez O.A., Donmez-Altuntas H., Gattas G., Giri A., Giri S., Gomez-Meda B., Gomez-Arroyo S., Hadjidekova V., Haveric A., Kamboj M., Kurteshi K., Martino-Roth M.G., Montero M.R., Nersesyan A., Pastor-Benito S., Favero Salvadori D.M., Shaposhnikova A., Stopper H., Thomas P., Torres-Bugarin O., Yadav A.S., Zuniga G.G., Fenech M. The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN(XL)): the role of life-style, host factors, occupational exposures, health status, and assay protocol. Mutat. Res. 2011, 728:88-97.
12. Fenech M., Bonassi S. The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes. Mutagenesis 2011, 26:43-49.
13. Gronniger E., Weber B., Heil O., Peters N., Stab F., Wenck H., Korn B., Winnefeld M., Lyko F. Aging and chronic sun exposure cause distinct epigenetic changes in human skin. PLoS Genet. 2010, 6:e1000971.
14. Nelson H.H., Marsit C.J., Kelsey K.T. Global methylation in exposure biology and translational medical science. Environ. Health Perspect. 2011, 119:1528-1533.
15. Aypar U., Morgan W.F., Baulch J.E. Radiation-induced epigenetic alterations after low and high LET irradiations. Mutat. Res. 2011, 707:24-33.
16. Mittal A., Piyathilake C., Hara Y., Katiyar S.K. Exceptionally high protection of photocarcinogenesis by topical application of (-)-epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: relationship to inhibition of UVB-induced global DNA hypomethylation. Neoplasia 2003, 5:555-565.
17. Nair-Shalliker V., Clements M., Fenech M., Armstrong B.K. Personal sun exposure and serum 25-hydroxy vitamin D concentrations. Photochem. Photobiol. 2013, 89(1):208-214. http://www-ncbi-nlm-nih-gov.ezproxy2.library.usyd.edu.au/pubmed/22780860. 10.1111/j.1751-1097.2012.01201.x.
18. Verschaeve L., Koppen G., Gorp U.V., Schoeters G., Jacobs G., Zwijzen C. Seasonal variations in spontaneous levels of DNA dama≥ implication in the risk assessment of environmental chemicals. J. Appl. Toxicol. 2007, 27:612-620.
19. Nair-Shalliker V., Smith D.P., Egger S., Hughes A.M., Kaldor J.M., Clements M., Kricker A., Armstrong B.K. Sun exposure may increase risk of prostate cancer in the high UV environment of New South Wales, Australia: a case-control study. Int. J. Cancer 2012, 131:E726-E732.
20. Fenech M. Cytokinesis-block micronucleus cytome assay. Nat. Protoc. 2007, 2:1084-1104.
21. Lee D.H., Pfeifer G.P. Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis. J. Biol. Chem. 2003, 278:10314-10321.
22. Rochette P.J., Lacoste S., Therrien J.P., Bastien N., Brash D.E., Drouin R. Influence of cytosine methylation on ultraviolet-induced cyclobutane pyrimidine dimer formation in genomic DNA. Mutat. Res. 2009, 665:7-13.
23. Greinert R., Volkmer B., Henning S., Breitbart E.W., Greulich K.O., Cardoso M.C., Rapp A. UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages. Nucleic Acids Res. 2012, 40:10263-10273.
24. Perng W., Rozek L.S., Mora-Plazas M., Duchin O., Marin C., Forero Y., Baylin A., Villamor E. Micronutrient status and global DNA methylation in school-age children. Epigenetics 2012, 7:1133-1141.
25. Hande M.P., Balajee A.S., Natarajan A.T. Induction of telomerase activity by UV-irradiation in Chinese hamster cells. Oncogene 1997, 15:1747-1752.
26. Ghosh A., Saginc G., Leow S.C., Khattar E., Shin E.M., Yan T.D., Wong M., Zhang Z., Li G., Sung W.K., Zhou J., Chng W.J., Li S., Liu E., Tergaonkar V. Telomerase directly regulates NF-kappaB-dependent transcription. Nat. Cell Biol. 2012, 14:1270-1281.
27. Heyn H., Esteller M. DNA methylation profiling in the clinic: applications and challenges. Nat. Rev. Genet. 2012, 13:679-692.
28. Jones P.A. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet. 2012, 13:484-492.
29. Bestor T.H. The DNA methyltransferases of mammals. Hum. Mol. Genet. 2000, 9:2395-2402.
30. Xu G.L., Bestor T.H., Bourc'his D., Hsieh C.L., Tommerup N., Bugge M., Hulten M., Qu X., Russo J.J., Viegas-Pequignot E. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 1999, 402:187-191.
31. Chia S.E., Wong K.Y., Cheng C., Lau W., Tan P.H. Sun exposure and the risk of prostate cancer in the Singapore Prostate Cancer Study: a case-control study. Asian Pac. J. Cancer Prev. 2012, 13:3179-3185.
32. Rochette P.J., Brash D.E. Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair. PLoS Genet. 2010, 6:e1000926.
33. Opresko P.L., Fan J., Danzy S., Wilson D.M., Bohr V.A. Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2. Nucleic Acids Res. 2005, 33:1230-1239.
34. Soohoo C.Y., Shi R., Lee T.H., Huang P., Lu K.P., Zhou X.Z. Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation. J. Biol. Chem. 2011, 286:3894-3906.
35. van S.B., de L.T. Control of telomere length by the human telomeric protein TRF1. Nature 1997, 385:740-743.
36. Vera E., Canela A., Fraga M.F., Esteller M., Blasco M.A. Epigenetic regulation of telomeres in human cancer. Oncogene 2008, 27:6817-6833.
37. Borradale D.C., Kimlin M.G. Folate degradation due to ultraviolet radiation: possible implications for human health and nutrition. Nutr. Rev. 2012, 70:414-422.
38. Sanchez G.V., Weinstein S.J., Stolzenberg-Solomon R.Z. Is dietary fat, vitamin D, or folate associated with pancreatic cancer?. Mol. Carcinog. 2012, 51:119-127.