Rhinovirus-induced macrophage cytokine expression does not require endocytosis or replication

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 5, 2014, Pages 974-984

  Saba, Thomas G ^a   Chung, Yutein ^a   Hong, Jun Young ^a   Sajjan, Uma S ^a   Bentley, J Kelley ^a   Hershenson, Marc B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Asthma; Exacerbation; M2 polarization; Toll like receptor 2; Virus

Indexed keywords

CXCL1 CHEMOKINE; CYTOKINE; EOTAXIN 2; INTERLEUKIN 6; MACROPHAGE DERIVED CHEMOKINE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BONE MARROW; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; ENDOCYTOSIS; GENE EXPRESSION; IMMUNE RESPONSE; LUNG LAVAGE; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RHINOVIRUS; RHINOVIRUS INFECTION; SEROTYPE; ULTRAVIOLET IRRADIATION;

ANIMALS; CELLS, CULTURED; CHEMOKINE CXCL1; CYTOKINES; ENDOCYTOSIS; FEMALE; INTERLEUKIN-6; MACROPHAGES; MICE; MICE, INBRED BALB C; MYELOID DIFFERENTIATION FACTOR 88; RHINOVIRUS; RNA, VIRAL; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR-ALPHA; VIRUS REPLICATION;

EID: 84899705386     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0354OC     Document Type: Article

References (44)

1. Johnston SL, Pattemore PK, Sanderson G, Smith S, Lampe F, Josephs L, Symington P, O'Toole S, Myint SH, Tyrrell DA, et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ 1995;310:1225-1229.
2. Nicholson KG, Kent J, Ireland DC. Respiratory viruses and exacerbations of asthma in adults. BMJ 1993;307:982-986.
3. Gern JE, Dick EC, Lee WM, Murray S, Meyer K, Handzel ZT, Busse WW. Rhinovirus enters but does not replicate inside monocytes and airway macrophages. J Immunol 1996;156:621-627.
4. Laza-Stanca V, Stanciu LA, Message SD, Edwards MR, Gern JE, Johnston SL. Rhinovirus replication in human macrophages induces NF-kB-dependent tumor necrosis factor alpha production. J Virol 2006;80:8248-8258.
5. Hall DJ, Bates ME, Guar L, Cronan M, Korpi N, Bertics PJ. The role of p38 MAPK in rhinovirus-induced monocyte chemoattractant protein-1 production by monocytic-lineage cells. J Immunol 2005;174: 8056-8063.
6. Korpi-Steiner NL, Bates ME, Lee W-M, Hall DJ, Bertics PJ. Human rhinovirus induces robust IP-10 release by monocytic cells, which is independent of viral replication but linked to type I interferon receptor ligation and STAT1 activation. J Leukoc Biol 2006;80:1364-1374.
7. Johnston SL, Papi A, Monick MM, Hunninghake GW. Rhinoviruses induce interleukin-8 mRNA and protein production in human monocytes. J Infect Dis 1997;175:323-329.
8. Khaitov MR, Laza-Stanca V, Edwards MR, Walton RP, Rohde G, Contoli M, Papi A, Stanciu LA, Kotenko SV, Johnston SL. Respiratory virus induction of alpha-, beta-and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells. Allergy 2009; 64:375-386.
9. Nagarkar DR, Bowman ER, Schneider D, Wang Q, Shim J, Zhao Y, Linn MJ, McHenry CL, Gosangi B, Bentley JK, et al. Rhinovirus infection of allergen-sensitized and-challenged mice induces eotaxin release rom functionally polarized macrophages. J Immunol 2010;185:2525-2535.
10. Bentley JK, Sajjan US, Dzaman MB, Jarjour NN, Lee W-M, Gern JE, Hershenson MB. Rhinovirus colocalizes with CD68-and CD11bpositive macrophages after experimental infection in humans. J Allergy Clin Immunol 2013;758-761:2013.
11. Papi A, Johnston SL. Rhinovirus infection induces expression of its own receptor intercellular adhesion molecule 1 (ICAM-1) via increased NF-kappaB-mediated transcription. J Biol Chem 1999; 274:9707-9720.
12. Newcomb DC, Sajjan U, Nanua S, Jia Y, Goldsmith AM, Bentley JK, Hershenson MB. Phosphatidylinositol 3-kinase is required for rhinovirus-induced airway epithelial cell interleukin-8 expression. J Biol Chem 2005;280:36952-36961.
13. Martin S, Casasnovas JM, Staunton DE, Springer TA. Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/ immunoglobulin molecules. J Virol 1993;67:3561-3568.
14. Weischenfeldt J, Porse B. Bone marrow-derived macrophages (BMM): isolation and applications. CSH Protoc 2008;2008:pdb.prot5080.
15. Nagpal K, Plantinga TS, Sirois CM, Monks BG, Latz E, Netea MG, Golenbock DT. Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes. J Biol Chem 2011;286:11875-11882.
16. Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 2008;9:847-856.
17. Contoli M, Message SD, Laza-Stanca V, Edwards MR, Wark PA, Bartlett NW, Kebadze T, Mallia P, Stanciu LA, Parker HL, et al. Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med 2006;12:1023-1026.
18. Newcomb DC, Sajjan US, Nagarkar DR, Wang Q, Nanua S, Zhou Y, McHenry CL, Hennrick KT, Tsai WC, Bentley JK, et al. Human rhinovirus 1B exposure induces phosphatidylinositol 3-kinasedependent airway inflammation in mice. Am J Respir Crit Care Med 2008;177:1111-1121.
19. Martinez FO, Sica A, Mantovani A, Locati M. Macrophage activation and polarization. Front Biosci 2008;13:453-461.
20. Krausgruber T, Blazek K, Smallie T, Alzabin S, Lockstone H, Sahgal N, Hussell T, Feldmann M, Udalova IA. IRF5 promotes inflammatory macrophage polarization and Th1-Th17 responses. Nat Immunol 2011;12:231-238.
21. Ying S, O'Connor B, Ratoff J, Meng Q, Mallett K, Cousins D, Robinson D, Zhang G, Zhao J, Lee TH, et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol 2005;174:8183-8190.
22. Ravensberg AJ, Ricciardolo FLM, van Schadewijk A, Rabe KF, Sterk PJ, Hiemstra PS, Mauad T. Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge. J Allergy Clin Immunol 2005;115:779-785.
23. Crapster-Pregont M, Yeo J, Sanchez RL, Kuperman DA. Dendritic cells and alveolar macrophages mediate IL-13-induced airway inflammation and chemokine production. J Allergy Clin Immunol 2012;129:1621-1627, e3.
24. Staples KJ, Hinks TSC, Ward JA, Gunn V, Smith C, Djukanović R. Phenotypic characterization of lung macrophages in asthmatic patients: overexpression of CCL17. J Allergy Clin Immunol 2012;130: 1404-1412, e7.
25. Oliver BG, Lim S, Wark P, Laza-Stanca V, King N, Black JL, Burgess JK, Roth M, Johnston SL. Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages. Thorax 2008;63:519-525.
26. Wang Q, Miller DJ, Bowman ER, Nagarkar DR, Schneider D, Zhao Y, Linn MJ, Goldsmith AM, Bentley JK, Sajjan US, et al. MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness. PLoS Pathog 2011;7:e1002070.
27. Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, et al. Role of doublestranded RNA pattern recognition receptors in rhinovirusinduced airway epithelial cell responses. J Immunol 2009;183: 6989-6997.
28. Unger BL, Faris AN, Ganesan S, Comstock AT, Hershenson MB, Sajjan US. Rhinovirus attenuates non-typeable Hemophilus influenzaestimulated IL-8 responses via TLR2-dependent degradation of IRAK-1. PLoS Pathog 2012;8:e1002969.
29. Sha Q, Truong-Tran AQ, Plitt JR, Beck LA, Schleimer RP. Activation of airway epithelial cells by toll-like receptor agonists. Am J Respir Cell Mol Biol 2004;31:358-364.
30. Slater L, Bartlett NW, Haas JJ, Zhu J, Message SD, Walton RP, Sykes A, Dahdaleh S, Clarke DL, Belvisi MG, et al. Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium. PLoS Pathog 2010;6:e1001178.
31. Triantafilou K, Vakakis E, Richer EA, Evans GL, Villiers JP, Triantafilou M. Human rhinovirus recognition in non-immune cells is mediated by Toll-like receptors and MDA-5, which trigger a synergetic proinflammatory immune response. Virulence 2011;2:22-29.
32. Hellstrom M, Kalén M, Lindahl P, Abramsson A, Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development 1999;126:3047-3055.
33. Murawski MR, Bowen GN, Cerny AM, Anderson LJ, Haynes LM, Tripp RA, Kurt-Jones EA, Finberg RW. Respiratory syncytial virus activates innate immunity through Toll-like receptor. J Virol 2009;83: 1492-1500
34. Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000;1:398-401.
35. Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, et al. The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature 2013;497: 498-502.
36. Stein M, Keshav S, Harris N, Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 1992; 176:287-292.
37. Muller U, Stenzel W, Kohler G, Werner C, Polte T, Hansen G, Schutze N, Straubinger RK, Blessing M, McKenzie AN, et al. IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans. J Immunol 2007;179: 5367-5377.
38. Yamashita U, Kuroda E. Regulation of macrophage-derived chemokine (MDC, CCL22) production. Crit Rev Immunol 2002;22:105-114.
39. Ben-Yehuda C, Bader R, Puxeddu I, Levi-Schaffer F, Breuer R, Berkman N. Airway eosinophil accumulation and eotaxin-2/CCL24 expression following allergen challenge in BALB/c mice. Exp Lung Res 2008;34:467-479.
40. Tang C, Ward C, Reid D, Bish R, O'Byrne PM, Walters EH. Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma. J Allergy Clin Immunol 2001;107:863-870.
41. Hofer MF, Jirapongsananuruk O, Trumble AE, Leung DY. Upregulation of B7.2, but not B7.1, on B cells from patients with allergic asthma. J Allergy Clin Immunol 1998;101:96-102.
42. Agea E, Forenza N, Piattoni S, Russano A, Monaco A, Flenghi L, Bistoni O, Gillies DA, Azuma M, Bertotto A, et al. Expression of B7 costimulatory molecules and CD1a antigen by alveolar macrophages in allergic bronchial asthma. Clin Exp Allergy 1998;28:1359-1367.
43. Eder W, Klimecki W, Yu L, von Mutius E, Riedler J, Braun-Fahrlä nder C, Nowak D, Martinez FD. Toll-like receptor 2 as a major gene for asthma in children of European farmers. J Allergy Clin Immunol 2004; 113:482-488.
44. Custovic A, Rothers J, Stern D, Simpson A, Woodcock A, Wright AL, Nicolaou NC, Hankinson J, Halonen M, Martinez FD. Effect of day care attendance on sensitization and atopic wheezing differs by Tolllike receptor 2 genotype in 2 population-based birth cohort studies. J Allergy Clin Immunol 2011;127:390-397, e1-9.