Doxorubicin loaded pH-responsive micelles capable of rapid intracellular drug release for potential tumor therapy

Journal of Biomedical Nanotechnology

Volumn 10, Issue 8, 2014, Pages 1480-1489

  Li, Shuai ^a   Wu, Wei ^a   Xiu, Kemao ^b   Xu, Fujian ^b   Li, Zhongming ^a   Li, Jianshu ^a  

^a SICHUAN UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

Block copolymer; Doxorubicin; Drug delivery system; Micelles; pH sensitive; Rapid intracellular release

Indexed keywords

ATOM TRANSFER RADICAL POLYMERIZATION; BLOCK COPOLYMERS; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY; DYNAMIC LIGHT SCATTERING; ENCAPSULATION; GEL PERMEATION CHROMATOGRAPHY; MICELLES; PH; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

AMPHIPHILIC BLOCK COPOLYMERS; AMPHIPHILIC DIBLOCK COPOLYMERS; CRITICAL MICELLE CONCENTRATION (CMC); DOXORUBICIN; DRUG DELIVERY SYSTEM; GEL PERMEATION CHROMATOGRAPHY (GPC); PH SENSITIVE; RAPID INTRACELLULAR RELEASE;

LOADING;

COPOLYMER; DOXORUBICIN; POLY(2 DIISOPROPYLAMINOETHYL METHACRYLATE) B POLY(2 AMINOETHYL METHACRYLATE HYDROCHLORIDE); UNCLASSIFIED DRUG;

ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; BIOCOMPATIBILITY; CANCER THERAPY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; GEL PERMEATION CHROMATOGRAPHY; HYDROPHILICITY; IN VITRO STUDY; LIGHT SCATTERING; PARTICLE SIZE; PH; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; SYNTHESIS; THERMODYNAMICS; THERMOSTABILITY; TRANSMISSION ELECTRON MICROSCOPY;

ANTINEOPLASTIC AGENTS; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; HELA CELLS; HUMANS; MICELLES; NANOPARTICLES; POLYMETHACRYLIC ACIDS;

EID: 84899698052     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2014.1846     Document Type: Article

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