DPP-4 inhibitor attenuates toxic effects of indoxyl sulfate on kidney tubular cells

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Wang, Wei Jie ^a,b   Chang, Chen Hung ^b   Sun, Mao Feng ^c,d   Hsu, Sheng Feng ^c,d   Weng, Ching Sung ^a,c  

^a CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

^b TAO YUAN GENERAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CASPASE 3; DIPEPTIDYL PEPTIDASE IV INHIBITOR; INDICAN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BIOSYNTHESIS; CELL VIABILITY; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; NEPHROTOXICITY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RENAL PROTECTION; UPREGULATION; APOPTOSIS; CELL LINE; CELL SURVIVAL; CYTOSOL; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; FIBROSIS; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TOXICITY;

APOPTOSIS; CASPASE 3; CELL LINE; CELL SURVIVAL; CYTOSOL; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROSIS; HUMANS; INDICAN; KIDNEY TUBULES, PROXIMAL; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899692712     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093447     Document Type: Article

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