-
1
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994; 367: 645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
-
2
-
-
84858608410
-
Cancer stem cells: Impact, heterogeneity, and uncertainty
-
Magee JA, Piskounova E, Morrison SJ. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 2012; 21: 283-296.
-
(2012)
Cancer Cell
, vol.21
, pp. 283-296
-
-
Magee, J.A.1
Piskounova, E.2
Morrison, S.J.3
-
3
-
-
84862517728
-
Cancer stem cells: Current status and evolving complexities
-
Visvader JE, Lindeman GJ. Cancer stem cells: current status and evolving complexities. Cell Stem Cell 2012; 10: 717-728.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 717-728
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
4
-
-
80053206941
-
Therapeutic approaches to target cancer stem cells
-
Diaz A, Leon K. Therapeutic approaches to target cancer stem cells. Cancers (Basel) 2011; 3: 3331-3352.
-
(2011)
Cancers (Basel)
, vol.3
, pp. 3331-3352
-
-
Diaz, A.1
Leon, K.2
-
5
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery
-
Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat Rev Drug Discov 2009; 8: 806-823.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 806-823
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
6
-
-
84899511684
-
Targeting Human Cancer Stem Cells with Monoclonal Antibodies
-
Naujokat C. Targeting Human Cancer Stem Cells with Monoclonal Antibodies. J Clin Cell Immunol 2012; S5: 007.
-
(2012)
J Clin Cell Immunol
, vol.S5
, pp. 007
-
-
Naujokat, C.1
-
7
-
-
84871980094
-
TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo
-
Perlstein B, Finniss SA, Miller C, et al. TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo. Neuro Oncol 2013; 15: 29-40.
-
(2013)
Neuro Oncol
, vol.15
, pp. 29-40
-
-
Perlstein, B.1
Finniss, S.A.2
Miller, C.3
-
8
-
-
84879678207
-
MicroRNA-21 regulates the migration and invasion of a stem-like population in hepatocellular carcinoma
-
Zhou L, Yang ZX, Song WJ, et al. MicroRNA-21 regulates the migration and invasion of a stem-like population in hepatocellular carcinoma. Int J Oncol 2013; 43: 661-669.
-
(2013)
Int J Oncol
, vol.43
, pp. 661-669
-
-
Zhou, L.1
Yang, Z.X.2
Song, W.J.3
-
9
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 2011; 17: 211-215.
-
(2011)
Nat Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
-
10
-
-
80555145216
-
Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: Molecular mechanisms
-
Singh BN, Fu J, Srivastava RK, Shankar S. Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms. PLoS One 2011; 6: e27306.
-
(2011)
PLoS One
, vol.6
-
-
Singh, B.N.1
Fu, J.2
Srivastava, R.K.3
Shankar, S.4
-
11
-
-
70350236531
-
Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties
-
Luistro L, He W, Smith M, et al. Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties. Cancer Res 2009; 69: 7672-7680.
-
(2009)
Cancer Res
, vol.69
, pp. 7672-7680
-
-
Luistro, L.1
He, W.2
Smith, M.3
-
12
-
-
84874041832
-
VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer
-
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther 2013; 12: 151-161.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 151-161
-
-
Hart, S.1
Novotny-Diermayr, V.2
Goh, K.C.3
-
13
-
-
84876532191
-
Combination effect of paclitaxel and hyaluronic acid on cancer stemlike side population cells
-
Lee H, Kim JB, Park SY, Kim SS, Kim H. Combination effect of paclitaxel and hyaluronic acid on cancer stemlike side population cells. J Biomed Nanotechnol 2013; 9: 299-302.
-
(2013)
J Biomed Nanotechnol
, vol.9
, pp. 299-302
-
-
Lee, H.1
Kim, J.B.2
Park, S.Y.3
Kim, S.S.4
Kim, H.5
-
14
-
-
84890570353
-
Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line
-
Fang DD, Cao J, Jani JP, et al. Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line. Front Med 2013; 7: 462-476.
-
(2013)
Front Med
, vol.7
, pp. 462-476
-
-
Fang, D.D.1
Cao, J.2
Jani, J.P.3
-
15
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta PB, Onder TT, Jiang G, et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 2009; 138: 645-659.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
-
16
-
-
79951950284
-
All-trans retinoic acid stealth liposomes prevent the relapse of breast cancer arising from the cancer stem cells
-
Li RJ, Ying X, Zhang Y, et al. All-trans retinoic acid stealth liposomes prevent the relapse of breast cancer arising from the cancer stem cells. J Control Release 2011; 149: 281-291.
-
(2011)
J Control Release
, vol.149
, pp. 281-291
-
-
Li, R.J.1
Ying, X.2
Zhang, Y.3
-
17
-
-
78650404347
-
Effects of stealth liposomal daunorubicin plus tamoxifen on the breast cancer and cancer stem cells
-
Guo J, Zhou J, Ying X, et al. Effects of stealth liposomal daunorubicin plus tamoxifen on the breast cancer and cancer stem cells. J Pharm Pharm Sci 2010; 13: 136-151.
-
(2010)
J Pharm Pharm Sci
, vol.13
, pp. 136-151
-
-
Guo, J.1
Zhou, J.2
Ying, X.3
-
18
-
-
79952341098
-
A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors
-
Lim KJ, Bisht S, Bar EE, Maitra A, Eberhart CG. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol Ther 2011; 11: 464-473.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 464-473
-
-
Lim, K.J.1
Bisht, S.2
Bar, E.E.3
Maitra, A.4
Eberhart, C.G.5
-
19
-
-
84862804254
-
The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy
-
Burke AR, Singh RN, Carroll DL, et al. The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy. Biomaterials 2012; 33: 2961-2970.
-
(2012)
Biomaterials
, vol.33
, pp. 2961-2970
-
-
Burke, A.R.1
Singh, R.N.2
Carroll, D.L.3
-
20
-
-
78149460436
-
Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells
-
Herrmann I, Baeuerle PA, Friedrich M, et al. Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells. PLoS One 2010; 5: e13474.
-
(2010)
PLoS One
, vol.5
-
-
Herrmann, I.1
Baeuerle, P.A.2
Friedrich, M.3
-
21
-
-
84899515010
-
Targeting CD44 in head and neck squamous cell carcinoma (HNSCC) with a new humanized antibody RO5429083
-
abstract doi: 10.1158/1538-7445.AM2012-2521
-
Perez, A, Neskey DM, Wen J, et al. Targeting CD44 in head and neck squamous cell carcinoma (HNSCC) with a new humanized antibody RO5429083. Cancer Res 2012; 72 (Suppl. 1): abstract 2521. doi: 10.1158/1538-7445.AM2012-2521
-
(2012)
Cancer Res
, vol.72
, Issue.SUPPL. 1
, pp. 2521
-
-
Perez, A.1
Neskey, D.M.2
Wen, J.3
-
22
-
-
84873441517
-
Mechanisms promoting physiological cells progression into tumorigenesis
-
Korbut E, Ptak-Belowska A, Brzozowski T. Mechanisms promoting physiological cells progression into tumorigenesis. J Physiol Pharmacol 2012; 63: 565-570.
-
(2012)
J Physiol Pharmacol
, vol.63
, pp. 565-570
-
-
Korbut, E.1
Ptak-Belowska, A.2
Brzozowski, T.3
-
24
-
-
84856389509
-
RNA-based therapeutics: Current progress and future prospects
-
Burnett JC, Rossi JJ. RNA-based therapeutics: current progress and future prospects. Chem Biol 2012; 19: 60-71.
-
(2012)
Chem Biol
, vol.19
, pp. 60-71
-
-
Burnett, J.C.1
Rossi, J.J.2
-
25
-
-
74049124186
-
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
-
Jackson AL. Linsley PS. Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat Rev Drug Discov 2010; 9: 57-67.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 57-67
-
-
Jackson, A.L.1
Linsley, P.S.2
-
26
-
-
84857185112
-
Delivery and biodistribution of siRNA for cancer therapy: Challenges and future prospects
-
Seth S, Johns R, Templin MV. Delivery and biodistribution of siRNA for cancer therapy: challenges and future prospects. Ther Deliv 2012; 3: 245-261.
-
(2012)
Ther Deliv
, vol.3
, pp. 245-261
-
-
Seth, S.1
Johns, R.2
Templin, M.V.3
-
27
-
-
0032213456
-
Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptidespecific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors
-
Zaks TZ, Rosenberg SA. Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptidespecific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors. Cancer Res 1998; 58: 4902-4908.
-
(1998)
Cancer Res
, vol.58
, pp. 4902-4908
-
-
Zaks, T.Z.1
Rosenberg, S.A.2
-
29
-
-
84899648905
-
-
Materials at
-
Materials at http://foundation.aarp.org.
-
-
-
-
30
-
-
84857477790
-
Global analysis of small molecule binding to related protein targets
-
Kruger FA, Overington JP. Global analysis of small molecule binding to related protein targets. PLoS Comput Biol 2012; 8: e1002333.
-
(2012)
PLoS Comput Biol
, vol.8
-
-
Kruger, F.A.1
Overington, J.P.2
-
31
-
-
84860455486
-
Discovery of small molecule cancer drugs: Successes, challenges and opportunities
-
Hoelder S, Clarke PA, Workman P. Discovery of small molecule cancer drugs: successes, challenges and opportunities. Mol Oncol 2012; 6: 155-176.
-
(2012)
Mol Oncol
, vol.6
, pp. 155-176
-
-
Hoelder, S.1
Clarke, P.A.2
Workman, P.3
-
32
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986; 46: 6387-6392.
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
33
-
-
79953048071
-
Tumor delivery of macromolecular drugs based on the EPR effect
-
Torchilin V. Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev 2011; 63: 131-135.
-
(2011)
Adv Drug Deliv Rev
, vol.63
, pp. 131-135
-
-
Torchilin, V.1
-
34
-
-
12144288634
-
Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles
-
Steiniger SC, Kreuter J, Khalansky AS, et al. Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles. Int J Cancer 2004; 109: 759-767.
-
(2004)
Int J Cancer
, vol.109
, pp. 759-767
-
-
Steiniger, S.C.1
Kreuter, J.2
Khalansky, A.S.3
-
35
-
-
70349566804
-
In vitro cytotoxicity of novel pro-apoptotic agent DM-PIT-1 in PEG-PE-based micelles alone and in combination with TRAIL
-
Skidan I, Miao B, Thekkedath RV, Dholakia P, Degterev A, Torchilin V. In vitro cytotoxicity of novel pro-apoptotic agent DM-PIT-1 in PEG-PE-based micelles alone and in combination with TRAIL. Drug Deliv 2009; 16: 45-51.
-
(2009)
Drug Deliv
, vol.16
, pp. 45-51
-
-
Skidan, I.1
Miao, B.2
Thekkedath, R.V.3
Dholakia, P.4
Degterev, A.5
Torchilin, V.6
-
36
-
-
47649099709
-
Photodynamic therapy of experimental B-16 melanoma in mice with tumor-targeted 5,10,15,20-tetraphenylporphin-loaded PEG-PE micelles
-
Skidan I, Dholakia P, Torchilin V. Photodynamic therapy of experimental B-16 melanoma in mice with tumor-targeted 5,10,15,20-tetraphenylporphin-loaded PEG-PE micelles. J Drug Target 2008; 16: 486-493.
-
(2008)
J Drug Target
, vol.16
, pp. 486-493
-
-
Skidan, I.1
Dholakia, P.2
Torchilin, V.3
-
37
-
-
78650546282
-
Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains
-
Miao B, Skidan I, Yang J, et al. Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains. Proc Natl Acad Sci USA 2010; 107: 20126-20131.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20126-20131
-
-
Miao, B.1
Skidan, I.2
Yang, J.3
-
38
-
-
84862517569
-
Best practices in cancer nanotechnology: Perspective from NCI nanotechnology alliance
-
Zamboni WC, Torchilin V, Patri AK, et al. Best practices in cancer nanotechnology: perspective from NCI nanotechnology alliance. Clin Cancer Res 2012; 18: 3229-3241.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3229-3241
-
-
Zamboni, W.C.1
Torchilin, V.2
Patri, A.K.3
-
39
-
-
77955276217
-
The delivery of doxorubicin to 3-D multicellular spheroids and tumors in a murine xenograft model using tumor-penetrating triblock polymeric micelles
-
Kim TH, Mount CW, Gombotz WR, Pun SH. The delivery of doxorubicin to 3-D multicellular spheroids and tumors in a murine xenograft model using tumor-penetrating triblock polymeric micelles. Biomaterials 2010; 31: 7386-7397.
-
(2010)
Biomaterials
, vol.31
, pp. 7386-7397
-
-
Kim, T.H.1
Mount, C.W.2
Gombotz, W.R.3
Pun, S.H.4
-
40
-
-
84855778719
-
Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133
-
Bourseau-Guilmain E, Bejaud J, Griveau A, et al. Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133. Int J Pharm 2012; 423: 93-101.
-
(2012)
Int J Pharm
, vol.423
, pp. 93-101
-
-
Bourseau-Guilmain, E.1
Bejaud, J.2
Griveau, A.3
-
41
-
-
75449112994
-
The intracellular drug delivery and anti tumor activity of doxorubicin loaded poly(gamma-benzyl L-glutamate)-b-hyaluronan polymersomes
-
Upadhyay KK, Bhatt AN, Mishra AK, et al. The intracellular drug delivery and anti tumor activity of doxorubicin loaded poly(gamma-benzyl L-glutamate)-b-hyaluronan polymersomes. Biomaterials 2010; 31: 2882-2892.
-
(2010)
Biomaterials
, vol.31
, pp. 2882-2892
-
-
Upadhyay, K.K.1
Bhatt, A.N.2
Mishra, A.K.3
-
42
-
-
50349086791
-
A paclitaxelhyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity
-
Banzato A, Bobisse S, Rondina M, et al. A paclitaxelhyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity. Clin Cancer Res 2008; 14: 3598-3606.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3598-3606
-
-
Banzato, A.1
Bobisse, S.2
Rondina, M.3
-
43
-
-
84859450097
-
Cancer stem cells and drug resistance: The potential of nanomedicine
-
Vinogradov S, Wei X. Cancer stem cells and drug resistance: the potential of nanomedicine. Nanomedicine (Lond) 2012; 7: 597-615.
-
(2012)
Nanomedicine (Lond)
, vol.7
, pp. 597-615
-
-
Vinogradov, S.1
Wei, X.2
-
44
-
-
84872040888
-
Targeting the tumor microenvironment for cancer therapy
-
Sounni NE, Noel A. Targeting the tumor microenvironment for cancer therapy. Clin Chem 2013; 59: 85-93.
-
(2013)
Clin Chem
, vol.59
, pp. 85-93
-
-
Sounni, N.E.1
Noel, A.2
-
47
-
-
84877666481
-
CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches
-
Epub 2013/04/20
-
Williams K, Motiani K, Giridhar PV, Kasper S. CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches. Exp Biol Med (Maywood) 2013; 238: 324-338. Epub 2013/04/20.
-
(2013)
Exp Biol Med (Maywood)
, vol.238
, pp. 324-338
-
-
Williams, K.1
Motiani, K.2
Giridhar, P.V.3
Kasper, S.4
-
48
-
-
59449092847
-
CD24 expression is a novel prognostic factor in esophageal squamous cell carcinoma
-
Sano A, Kato H, Sakurai S, et al. CD24 expression is a novel prognostic factor in esophageal squamous cell carcinoma. Ann Surg Oncol 2009; 16: 506-514.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 506-514
-
-
Sano, A.1
Kato, H.2
Sakurai, S.3
-
49
-
-
33646428091
-
Normal stem cells and cancer stem cells: The niche matters
-
Li L, Neaves WB. Normal stem cells and cancer stem cells: the niche matters. Cancer Res 2006; 66: 4553-4557.
-
(2006)
Cancer Res
, vol.66
, pp. 4553-4557
-
-
Li, L.1
Neaves, W.B.2
-
51
-
-
33947310596
-
Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis
-
Kryczek I, Wei S, Keller E, Liu R, Zou W. Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis. Am J Physiol Cell Physiol 2007; 292: C987-C995.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Kryczek, I.1
Wei, S.2
Keller, E.3
Liu, R.4
Zou, W.5
-
52
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
53
-
-
84899634297
-
Cancer stem cells and the bone marrow microenvironment
-
Shiozawa Y, Taichman RS. Cancer stem cells and the bone marrow microenvironment. Bonekey Rep 2012; 2012: 48.
-
(2012)
Bonekey Rep
, vol.2012
, pp. 48
-
-
Shiozawa, Y.1
Taichman, R.S.2
-
54
-
-
77956574908
-
More than markers: Biological significance of cancer stem cell-defining molecules
-
Keysar SB, Jimeno A. More than markers: biological significance of cancer stem cell-defining molecules. Mol Cancer Ther 2010; 9: 2450-2457.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2450-2457
-
-
Keysar, S.B.1
Jimeno, A.2
-
55
-
-
84881453720
-
Understanding and targeting cancer stem cells: Therapeutic implications and challenges
-
Chen K, Huang YH, Chen JL. Understanding and targeting cancer stem cells: therapeutic implications and challenges. Acta Pharmacol Sin 2013; 34: 732-740.
-
(2013)
Acta Pharmacol Sin
, vol.34
, pp. 732-740
-
-
Chen, K.1
Huang, Y.H.2
Chen, J.L.3
-
56
-
-
80355126175
-
Cancer stem cell markers as potential targets for epithelial cancers
-
Madka V, Rao CV. Cancer stem cell markers as potential targets for epithelial cancers. Indian J Exp Biol 2011; 49: 826-835.
-
(2011)
Indian J Exp Biol
, vol.49
, pp. 826-835
-
-
Madka, V.1
Rao, C.V.2
-
57
-
-
84886928384
-
Gastric stem cells and gastric cancer stem cells
-
Han ME, Oh SO. Gastric stem cells and gastric cancer stem cells. Anat Cell Biol 2013; 46: 8-18.
-
(2013)
Anat Cell Biol
, vol.46
, pp. 8-18
-
-
Han, M.E.1
Oh, S.O.2
-
58
-
-
84877707252
-
From "magic bullets" to specific cancer immunotherapy
-
doi: 10.4414/smw.2013.13734
-
Riether C, Schurch C, Ochsenbein AF. From "magic bullets" to specific cancer immunotherapy. Swiss Med Wkly 2013; 143: w13734. doi: 10.4414/smw.2013.13734.
-
(2013)
Swiss Med Wkly
, vol.143
-
-
Riether, C.1
Schurch, C.2
Ochsenbein, A.F.3
-
59
-
-
35148899178
-
Destemming cancer stem cells
-
Hill RP, Perris R. "Destemming" cancer stem cells. J Nat Cancer Inst 2007; 99: 1435-1440.
-
(2007)
J Nat Cancer Inst
, vol.99
, pp. 1435-1440
-
-
Hill, R.P.1
Perris, R.2
-
60
-
-
66949150208
-
Targeting stem cellsclinical implications for cancer therapy
-
Tu LC, Foltz G, Lin E, Hood L, Tian Q. Targeting stem cellsclinical implications for cancer therapy. Curr Stem Cell Res Ther 2009; 4: 147-153.
-
(2009)
Curr Stem Cell Res Ther
, vol.4
, pp. 147-153
-
-
Tu, L.C.1
Foltz, G.2
Lin, E.3
Hood, L.4
Tian, Q.5
-
61
-
-
80052841078
-
MicroRNA regulation of cancer stem cells
-
Liu C, Tang DG. MicroRNA regulation of cancer stem cells. Cancer Res 2011; 71: 5950-5954.
-
(2011)
Cancer Res
, vol.71
, pp. 5950-5954
-
-
Liu, C.1
Tang, D.G.2
-
62
-
-
53149105484
-
Cancer stem cell markers in common cancers-therapeutic implications
-
Klonisch T, Wiechec E, Hombach-Klonisch S, et al. Cancer stem cell markers in common cancers-therapeutic implications. Trends Mol Med 2008; 14:450-460.
-
(2008)
Trends Mol Med
, vol.14
, pp. 450-460
-
-
Klonisch, T.1
Wiechec, E.2
Hombach-Klonisch, S.3
-
63
-
-
79957622341
-
Concise review: Emerging concepts in clinical targeting of cancer stem cells
-
Rasheed ZA, Kowalski J, Smith BD, Matsui W. Concise review: Emerging concepts in clinical targeting of cancer stem cells. Stem Cells 2011; 29: 883-887.
-
(2011)
Stem Cells
, vol.29
, pp. 883-887
-
-
Rasheed, Z.A.1
Kowalski, J.2
Smith, B.D.3
Matsui, W.4
-
64
-
-
33846239456
-
Beyond tumorigenesis: Cancer stem cells in metastasis
-
Li F, Tiede B, Massague J, Kang Y. Beyond tumorigenesis: cancer stem cells in metastasis. Cell Res 2007; 17: 3-14.
-
(2007)
Cell Res
, vol.17
, pp. 3-14
-
-
Li, F.1
Tiede, B.2
Massague, J.3
Kang, Y.4
-
65
-
-
69249106131
-
Ovarian cancer: Emerging concept on cancer stem cells
-
Ponnusamy MP, Batra SK. Ovarian cancer: emerging concept on cancer stem cells. J Ovarian Res 2008; 1: 4.
-
(2008)
J Ovarian Res
, vol.1
, pp. 4
-
-
Ponnusamy, M.P.1
Batra, S.K.2
-
66
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007; 1: 555-567.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
-
67
-
-
58049195459
-
Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population
-
Steiniger SC, Coppinger JA, Kruger JA, Yates J, Janda KD. Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population. Stem Cells 2008; 26: 3037-3046.
-
(2008)
Stem Cells
, vol.26
, pp. 3037-3046
-
-
Steiniger, S.C.1
Coppinger, J.A.2
Kruger, J.A.3
Yates, J.4
Janda, K.D.5
-
68
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445: 106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
69
-
-
58649111264
-
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma
-
Read TA, Fogarty MP, Markant SL, et al. Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma. Cancer Cell 2009; 15: 135-147.
-
(2009)
Cancer Cell
, vol.15
, pp. 135-147
-
-
Read, T.A.1
Fogarty, M.P.2
Markant, S.L.3
-
70
-
-
84859169877
-
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
-
Barretina J, Caponigro G, Stransky N, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012; 483: 603-607.
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
Caponigro, G.2
Stransky, N.3
-
71
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006; 10: 515-527.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
-
72
-
-
31044441241
-
Gene expression profiling of breast cell lines identifies potential new basal markers
-
Charafe-Jauffret E, Ginestier C, Monville F, et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 2006; 25: 2273-2284.
-
(2006)
Oncogene
, vol.25
, pp. 2273-2284
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Monville, F.3
-
73
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, et al. Identification of pancreatic cancer stem cells. Cancer Res 2007; 67: 1030-1037.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
-
74
-
-
0025811882
-
The SCID mouse mutant: Definition, characterization, and potential uses
-
Bosma MJ, Carroll AM. The SCID mouse mutant: definition, characterization, and potential uses. Annu Rev Immunol 1991; 9: 323-350.
-
(1991)
Annu Rev Immunol
, vol.9
, pp. 323-350
-
-
Bosma, M.J.1
Carroll, A.M.2
-
75
-
-
18344410760
-
NOD/SCID/gamma(c)(null) mouse: An excellent recipient mouse model for engraftment of human cells
-
Ito M, Hiramatsu H, Kobayashi K, et al. NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood 2002; 100: 3175-3182.
-
(2002)
Blood
, vol.100
, pp. 3175-3182
-
-
Ito, M.1
Hiramatsu, H.2
Kobayashi, K.3
-
76
-
-
0028869986
-
Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice
-
Shultz LD, Schweitzer PA, Christianson SW, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol 1995; 154: 180-191.
-
(1995)
J Immunol
, vol.154
, pp. 180-191
-
-
Shultz, L.D.1
Schweitzer, P.A.2
Christianson, S.W.3
-
77
-
-
0026687159
-
Analysis of high complement levels in Mus hortulanus and BUB mice
-
Ong GL, Baker AE, Mattes MJ. Analysis of high complement levels in Mus hortulanus and BUB mice. J Immunol Methods 1992; 154: 37-45.
-
(1992)
J Immunol Methods
, vol.154
, pp. 37-45
-
-
Ong, G.L.1
Baker, A.E.2
Mattes, M.J.3
-
78
-
-
0032190418
-
Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral blood stem cells
-
van der Loo JC, Hanenberg H, Cooper RJ, Luo FY, Lazaridis EN, Williams DA. Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral blood stem cells. Blood 1998; 92: 2556-2570.
-
(1998)
Blood
, vol.92
, pp. 2556-2570
-
-
van der Loo, J.C.1
Hanenberg, H.2
Cooper, R.J.3
Luo, F.Y.4
Lazaridis, E.N.5
Williams, D.A.6
-
79
-
-
0036624736
-
The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse
-
Lock RB, Liem N, Farnsworth ML, et al. The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse. Blood 2002; 99: 4100-4108.
-
(2002)
Blood
, vol.99
, pp. 4100-4108
-
-
Lock, R.B.1
Liem, N.2
Farnsworth, M.L.3
-
80
-
-
38349165576
-
Identification of cells initiating human melanomas
-
Schatton T, Murphy GF, Frank NY, et al. Identification of cells initiating human melanomas. Nature 2008; 451: 345-349.
-
(2008)
Nature
, vol.451
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
-
82
-
-
0027049319
-
B and T cell leakiness in the scid mouse mutant
-
Bosma MJ. B and T cell leakiness in the scid mouse mutant. Immunodefic Rev 1992; 3: 261-276.
-
(1992)
Immunodefic Rev
, vol.3
, pp. 261-276
-
-
Bosma, M.J.1
-
83
-
-
20844434966
-
Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells
-
Shultz LD, Lyons BL, Burzenski LM, et al. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 2005; 174: 6477-6489.
-
(2005)
J Immunol
, vol.174
, pp. 6477-6489
-
-
Shultz, L.D.1
Lyons, B.L.2
Burzenski, L.M.3
-
84
-
-
0035704718
-
The athymic nude rat: An animal experimental model to reveal novel aspects of innate immune responses?
-
Rolstad B. The athymic nude rat: an animal experimental model to reveal novel aspects of innate immune responses? Immunol Rev 2001; 184: 136-144.
-
(2001)
Immunol Rev
, vol.184
, pp. 136-144
-
-
Rolstad, B.1
-
85
-
-
34247876272
-
Murine models to evaluate novel and conventional therapeutic strategies for cancer
-
Talmadge JE, Singh RK, Fidler IJ, Raz A. Murine models to evaluate novel and conventional therapeutic strategies for cancer. Am J Pathol 2007; 170: 793-804.
-
(2007)
Am J Pathol
, vol.170
, pp. 793-804
-
-
Talmadge, J.E.1
Singh, R.K.2
Fidler, I.J.3
Raz, A.4
-
86
-
-
33845267681
-
Characterization of stem cell-like cancer cells in immune-competent mice
-
Kruger JA, Kaplan CD, Luo Y, et al. Characterization of stem cell-like cancer cells in immune-competent mice. Blood 2006; 108: 3906-3912.
-
(2006)
Blood
, vol.108
, pp. 3906-3912
-
-
Kruger, J.A.1
Kaplan, C.D.2
Luo, Y.3
-
87
-
-
60549111070
-
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
-
Charafe-Jauffret E, Ginestier C, Iovino F, et al. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 2009; 69: 1302-1313.
-
(2009)
Cancer Res
, vol.69
, pp. 1302-1313
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Iovino, F.3
-
88
-
-
84865819534
-
Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) coinjection
-
Fridman R, Benton G, Aranoutova I, Kleinman HK, Bonfil RD. Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) coinjection. Nat Protoc 2012; 7: 1138-144.
-
(2012)
Nat Protoc
, vol.7
, pp. 1138-1144
-
-
Fridman, R.1
Benton, G.2
Aranoutova, I.3
Kleinman, H.K.4
Bonfil, R.D.5
-
89
-
-
78650797767
-
Engineered human tumor xenografts with functional human vascular networks
-
Alonso-Camino V, Santos-Valle P, Ispizua MC, Sanz L, Alvarez-Vallina L. Engineered human tumor xenografts with functional human vascular networks. Microvasc Res 2011; 81: 18-25.
-
(2011)
Microvasc Res
, vol.81
, pp. 18-25
-
-
Alonso-Camino, V.1
Santos-Valle, P.2
Ispizua, M.C.3
Sanz, L.4
Alvarez-Vallina, L.5
-
90
-
-
80052472086
-
Primary human tumor xenografted models ('tumorgrafts') for good management of patients with cancer
-
Decaudin D. Primary human tumor xenografted models ('tumorgrafts') for good management of patients with cancer. Anticancer Drugs 2011; 22: 827-841.
-
(2011)
Anticancer Drugs
, vol.22
, pp. 827-841
-
-
Decaudin, D.1
-
91
-
-
84861017334
-
Patient-derived xenografts of non small cell lung cancer: Resurgence of an old model for investigation of modern concepts of tailored therapy and cancer stem cells
-
Moro M, Bertolini G, Tortoreto M, Pastorino U, Sozzi G, Roz L. Patient-derived xenografts of non small cell lung cancer: resurgence of an old model for investigation of modern concepts of tailored therapy and cancer stem cells. J Biomed Biotechnol 2012; 2012: 568567.
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. 568567
-
-
Moro, M.1
Bertolini, G.2
Tortoreto, M.3
Pastorino, U.4
Sozzi, G.5
Roz, L.6
-
92
-
-
20144388256
-
An orthotopic model of anaplastic thyroid carcinoma in athymic nude mice
-
Kim S, Park YW, Schiff BA, et al. An orthotopic model of anaplastic thyroid carcinoma in athymic nude mice. Clin Cancer Res 2005; 11: 1713-1721.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1713-1721
-
-
Kim, S.1
Park, Y.W.2
Schiff, B.A.3
-
93
-
-
58149348625
-
An orthotopic murine model of sinonasal malignancy
-
Gelbard A, Kupferman ME, Jasser SA, et al. An orthotopic murine model of sinonasal malignancy. Clin Cancer Res 2008; 14: 7348-7357.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7348-7357
-
-
Gelbard, A.1
Kupferman, M.E.2
Jasser, S.A.3
-
94
-
-
44949226873
-
Tumour-stroma interactions in colorectal cancer: Converging on beta-catenin activation and cancer stemness
-
Le NH, Franken P, Fodde R. Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness. Br J Cancer 2008; 98: 1886-1893.
-
(2008)
Br J Cancer
, vol.98
, pp. 1886-1893
-
-
Le, N.H.1
Franken, P.2
Fodde, R.3
-
96
-
-
84884800205
-
A novel orthotopic mouse model of head and neck cancer and lymph node metastasis
-
Masood R, Hochstim C, Cervenka B, et al. A novel orthotopic mouse model of head and neck cancer and lymph node metastasis. Oncogenesis 2013; 2: e68.
-
(2013)
Oncogenesis
, vol.2
-
-
Masood, R.1
Hochstim, C.2
Cervenka, B.3
-
97
-
-
84863321158
-
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
-
doi: 10.1038/ncomms1892
-
Yae T, Tsuchihashi K, Ishimoto T, et al. Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat Commun 2012; 3: 883. doi: 10.1038/ncomms1892
-
(2012)
Nat Commun
, vol.3
, pp. 883
-
-
Yae, T.1
Tsuchihashi, K.2
Ishimoto, T.3
-
98
-
-
84876940883
-
CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer
-
Du L, Rao G, Wang H, et al. CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer. Cancer Res 2013; 73: 2682-2694.
-
(2013)
Cancer Res
, vol.73
, pp. 2682-2694
-
-
Du, L.1
Rao, G.2
Wang, H.3
-
99
-
-
84871484351
-
Thoughts about cancer stem cells in solid tumors
-
La Porta CA. Thoughts about cancer stem cells in solid tumors. World J Stem Cells 2012; 4: 17-20.
-
(2012)
World J Stem Cells
, vol.4
, pp. 17-20
-
-
La Porta, C.A.1
-
100
-
-
84892370492
-
Animal models of disease: Pre-clinical animal models of cancer and their applications and utility in drug Discovery
-
Ruggeri BA, Camp F. Miknyoczki S. Animal models of disease: pre-clinical animal models of cancer and their applications and utility in drug Discovery. Biochem Pharmacol 2013; 87: 150-161.
-
(2013)
Biochem Pharmacol
, vol.87
, pp. 150-161
-
-
Ruggeri, B.A.1
Camp, F.2
Miknyoczki, S.3
-
101
-
-
77950679333
-
Can animal models of disease reliably inform human studies?
-
doi: 10.1371/journal.pmed.1000245
-
van der Worp HB, Howells DW, Sena ES, et al. Can animal models of disease reliably inform human studies? PLoS Med 2010; 7: e1000245. doi: 10.1371/journal.pmed.1000245.
-
(2010)
PLoS Med
, vol.7
-
-
van der Worp, H.B.1
Howells, D.W.2
Sena, E.S.3
-
103
-
-
80053058993
-
Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells
-
doi: 10.1371/journal.pone.0024807
-
Lathia JD, Gallagher J, Myers JT, et al. Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. PloS One 2011; 6: e24807. doi: 10.1371/journal.pone.0024807.
-
(2011)
PloS One
, vol.6
-
-
Lathia, J.D.1
Gallagher, J.2
Myers, J.T.3
-
104
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ. Efficient tumour formation by single human melanoma cells. Nature 2008; 456: 593-598.
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
105
-
-
77957676330
-
Primary tumor genotype is an important determinant in identification of lung cancer propagating cells
-
Curtis SJ, Sinkevicius KW, Li D, et al. Primary tumor genotype is an important determinant in identification of lung cancer propagating cells. Cell Stem Cell 2010; 7: 127-133.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 127-133
-
-
Curtis, S.J.1
Sinkevicius, K.W.2
Li, D.3
-
106
-
-
77952302762
-
Mouse models for cancer stem cell research
-
Cheng L, Ramesh AV, Flesken-Nikitin A, Choi J, Nikitin AY. Mouse models for cancer stem cell research. Toxicol Pathol 2010; 38: 62-71.
-
(2010)
Toxicol Pathol
, vol.38
, pp. 62-71
-
-
Cheng, L.1
Ramesh, A.V.2
Flesken-Nikitin, A.3
Choi, J.4
Nikitin, A.Y.5
-
107
-
-
84867878045
-
Cancer stem cell definitions and terminology: The devil is in the details
-
Valent P, Bonnet D, De Maria R, et al. Cancer stem cell definitions and terminology: the devil is in the details. Nat Rev Cancer 2012; 12: 767-775.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 767-775
-
-
Valent, P.1
Bonnet, D.2
De Maria, R.3
-
108
-
-
77955534002
-
The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity
-
Park S, Jiang Z, Mortenson ED, et al. The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer Cell 2010; 18: 160-170.
-
(2010)
Cancer Cell
, vol.18
, pp. 160-170
-
-
Park, S.1
Jiang, Z.2
Mortenson, E.D.3
-
109
-
-
69249149701
-
Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens
-
Xu Q, Liu G, Yuan X, et al. Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens. Stem Cells 2009; 27: 1734-1740.
-
(2009)
Stem Cells
, vol.27
, pp. 1734-1740
-
-
Xu, Q.1
Liu, G.2
Yuan, X.3
-
110
-
-
0023734130
-
Transfer of a functional human immune system to mice with severe combined immunodeficiency
-
Mosier DE, Gulizia RJ, Baird SM, Wilson DB. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 1988; 335: 256-259.
-
(1988)
Nature
, vol.335
, pp. 256-259
-
-
Mosier, D.E.1
Gulizia, R.J.2
Baird, S.M.3
Wilson, D.B.4
-
111
-
-
0026581239
-
Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice
-
Lapidot T, Pflumio F, Doedens M, Murdoch B, Williams DE, Dick JE. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science 1992; 255: 1137-1141.
-
(1992)
Science
, vol.255
, pp. 1137-1141
-
-
Lapidot, T.1
Pflumio, F.2
Doedens, M.3
Murdoch, B.4
Williams, D.E.5
Dick, J.E.6
-
112
-
-
0033796870
-
Transplantation and growth characteristics of human fetal lymph node in immunodeficient mice
-
Shih CC, Hu J, Arber D, LeBon T, Forman SJ. Transplantation and growth characteristics of human fetal lymph node in immunodeficient mice. Exp Hematol 2000; 28: 1046-1053.
-
(2000)
Exp Hematol
, vol.28
, pp. 1046-1053
-
-
Shih, C.C.1
Hu, J.2
Arber, D.3
LeBon, T.4
Forman, S.J.5
-
113
-
-
0023753744
-
The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
-
McCune JM, Namikawa R, Kaneshima H, Shultz LD, Lieberman M, Weissman IL. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 1988; 241: 1632-1639.
-
(1988)
Science
, vol.241
, pp. 1632-1639
-
-
McCune, J.M.1
Namikawa, R.2
Kaneshima, H.3
Shultz, L.D.4
Lieberman, M.5
Weissman, I.L.6
-
114
-
-
84867898654
-
Humanized mice for immune system investigation: Progress, promise and challenges
-
Shultz LD, Brehm MA, Garcia-Martinez JV, Greiner DL. Humanized mice for immune system investigation: progress, promise and challenges. Nature Rev Immunol 2012; 12: 786-798.
-
(2012)
Nature Rev Immunol
, vol.12
, pp. 786-798
-
-
Shultz, L.D.1
Brehm, M.A.2
Garcia-Martinez, J.V.3
Greiner, D.L.4
-
116
-
-
79551617718
-
Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition
-
Shankar S, Nall D, Tang SN, et al. Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition. PloS One 2011; 6: e16530.
-
(2011)
PloS One
, vol.6
-
-
Shankar, S.1
Nall, D.2
Tang, S.N.3
-
117
-
-
84872861115
-
GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft
-
Fu J, Rodova M, Roy SK, et al. GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft. Cancer Lett 2013; 330: 22-32.
-
(2013)
Cancer Lett
, vol.330
, pp. 22-32
-
-
Fu, J.1
Rodova, M.2
Roy, S.K.3
-
118
-
-
80052265350
-
Humanized tumor mice-a new model to study and manipulate the immune response in advanced cancer therapy
-
Wege AK, Ernst W, Eckl J, et al. Humanized tumor mice-a new model to study and manipulate the immune response in advanced cancer therapy. Int J Cancer 2011; 129: 2194-2206.
-
(2011)
Int J Cancer
, vol.129
, pp. 2194-2206
-
-
Wege, A.K.1
Ernst, W.2
Eckl, J.3
-
119
-
-
1842687362
-
Reconstruction of functionally normal and malignant human breast tissues in mice
-
Kuperwasser C, Chavarria T, Wu M, et al. Reconstruction of functionally normal and malignant human breast tissues in mice. Proc Nat Acad Sci USA 2004; 101: 4966-4971.
-
(2004)
Proc Nat Acad Sci USA
, vol.101
, pp. 4966-4971
-
-
Kuperwasser, C.1
Chavarria, T.2
Wu, M.3
-
120
-
-
79955632648
-
Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells
-
Stewart JM, Shaw PA, Gedye C, Bernardini MQ, Neel BG, Ailles LE. Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells. Proc Nat Acad Sci USA 2011; 108: 6468-6473.
-
(2011)
Proc Nat Acad Sci USA
, vol.108
, pp. 6468-6473
-
-
Stewart, J.M.1
Shaw, P.A.2
Gedye, C.3
Bernardini, M.Q.4
Neel, B.G.5
Ailles, L.E.6
-
121
-
-
84859101558
-
The construction of transgenic and gene knockout/knockin mouse models of human disease
-
Doyle A, McGarry MP, Lee NA, Lee JJ. The construction of transgenic and gene knockout/knockin mouse models of human disease. Transgenic Res 2012; 21: 327-349.
-
(2012)
Transgenic Res
, vol.21
, pp. 327-349
-
-
Doyle, A.1
McGarry, M.P.2
Lee, N.A.3
Lee, J.J.4
-
122
-
-
0036642255
-
Knockout mice: Simple solutions to the problems of genetic background and flanking genes
-
Wolfer DP, Crusio WE, Lipp HP. Knockout mice: simple solutions to the problems of genetic background and flanking genes. Trends Neurosci 2002; 25: 336-340.
-
(2002)
Trends Neurosci
, vol.25
, pp. 336-340
-
-
Wolfer, D.P.1
Crusio, W.E.2
Lipp, H.P.3
-
123
-
-
79957936388
-
How genetically engineered mouse tumor models provide insights into human cancers
-
Politi K, Pao W. How genetically engineered mouse tumor models provide insights into human cancers. J Clin Oncol 2011; 29: 2273-2281.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2273-2281
-
-
Politi, K.1
Pao, W.2
-
124
-
-
66149148652
-
Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine
-
Snippert HJ, van Es JH, van den Born M, et al. Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine. Gastroenterology 2009; 136: 2187-2194.
-
(2009)
Gastroenterology
, vol.136
, pp. 2187-2194
-
-
Snippert, H.J.1
van Es, J.H.2
van den Born, M.3
-
125
-
-
84863938543
-
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
-
Gurney A, Axelrod F, Bond CJ, et al. Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors. Proc Nat Acad Sci USA 2012; 109: 11717-11722.
-
(2012)
Proc Nat Acad Sci USA
, vol.109
, pp. 11717-11722
-
-
Gurney, A.1
Axelrod, F.2
Bond, C.J.3
-
126
-
-
62449205665
-
Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
-
Dallas NA, Xia L, Fan F, et al. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res 2009; 69: 1951-1957.
-
(2009)
Cancer Res
, vol.69
, pp. 1951-1957
-
-
Dallas, N.A.1
Xia, L.2
Fan, F.3
|