메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

Lactobacillus amylovorus inhibits the TLR4 inflammatory signaling triggered by enterotoxigenic Escherichia coli via modulation of the negative regulators and involvement of TLR2 in intestinal caco-2 cells and pig explants

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 72; HEAT SHOCK PROTEIN 90; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; INTERLEUKIN 1BETA; INTERLEUKIN 8; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN TOLLIP; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; AUTACOID; CYTOKINE;

EID: 84899641527     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094891     Document Type: Article
Times cited : (126)

References (61)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 63649108380 scopus 로고    scopus 로고
    • The roles of TLRs, RLRs and NLRs in pathogen recognition
    • Kawai T, Akira S (2009) The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 21: 317-337.
    • (2009) Int Immunol , vol.21 , pp. 317-337
    • Kawai, T.1    Akira, S.2
  • 3
    • 67649422321 scopus 로고    scopus 로고
    • Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
    • O'Neill LA, Bryant CE, Doyle SL (2009) Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer. Pharm Rev 61: 177-197.
    • (2009) Pharm Rev , vol.61 , pp. 177-197
    • O'Neill, L.A.1    Bryant, C.E.2    Doyle, S.L.3
  • 4
    • 77249150015 scopus 로고    scopus 로고
    • The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis
    • Lavelle EC, Murphy C, O'Neill LA, Creagh EM (2010) The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis. Mucosal Immunol 3: 17-28.
    • (2010) Mucosal Immunol , vol.3 , pp. 17-28
    • Lavelle, E.C.1    Murphy, C.2    O'Neill, L.A.3    Creagh, E.M.4
  • 5
    • 77349100136 scopus 로고    scopus 로고
    • Associations between mucosal innate and adaptive immune responses and resolution of diarrheal pathogen infections
    • Long KZ, Rosado JL, Santos JI, Haas M, Al Mamun A, et al. (2010) Associations between mucosal innate and adaptive immune responses and resolution of diarrheal pathogen infections. Infect Immun 78: 1221-1228.
    • (2010) Infect Immun , vol.78 , pp. 1221-1228
    • Long, K.Z.1    Rosado, J.L.2    Santos, J.I.3    Haas, M.4    Al Mamun, A.5
  • 6
    • 38549090164 scopus 로고    scopus 로고
    • Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line
    • Moue M, Tohno M, Shimazu T, Kido T, Aso H, et al. (2008) Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line. Biochim Biophys Acta 1780: 134-144.
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 134-144
    • Moue, M.1    Tohno, M.2    Shimazu, T.3    Kido, T.4    Aso, H.5
  • 7
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • Rakoff-Nahoum S, Pagina J, Eslami-Varzaneh F, Edberg S, Medzhitov R (2004) Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118: 229-241.
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Pagina, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 8
    • 84888289662 scopus 로고    scopus 로고
    • Increased Th17-Inducing activity of CD14(+) CD163(low) myeloid cells in intestinal lamina propria of patients with crohn's disease
    • Ogino T, Nishimura J, Barman S, Kayama H, Uematsu S, et al. (2013) Increased Th17-Inducing Activity of CD14(+) CD163(low) Myeloid Cells in Intestinal Lamina Propria of Patients With Crohn's Disease. Gastroenterology 145: 1380-1391.
    • (2013) Gastroenterology , vol.145 , pp. 1380-1391
    • Ogino, T.1    Nishimura, J.2    Barman, S.3    Kayama, H.4    Uematsu, S.5
  • 9
    • 0036080092 scopus 로고    scopus 로고
    • Tolllike receptors 2 and 4 are up-regulated during intestinal inflammation
    • Hausmann M, Kiessling S, Mestermann S, Webb G, Spöttl T, et al. (2002) Tolllike receptors 2 and 4 are up-regulated during intestinal inflammation. Gastroenterology 122: 1987-2000.
    • (2002) Gastroenterology , vol.122 , pp. 1987-2000
    • Hausmann, M.1    Kiessling, S.2    Mestermann, S.3    Webb, G.4    Spöttl, T.5
  • 11
    • 1242336786 scopus 로고    scopus 로고
    • Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice
    • Oyama J, Blais CJr, Liu X, Pu M, Kobzik L, et al. (2004) Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice. Circulation 109: 784-789.
    • (2004) Circulation , vol.109 , pp. 784-789
    • Oyama, J.1    Blais, C.J.R.2    Liu, X.3    Pu, M.4    Kobzik, L.5
  • 12
    • 39349110899 scopus 로고    scopus 로고
    • Heat shock proteins and toll-like receptors
    • Asea A (2008) Heat shock proteins and toll-like receptors. Handb Exp Pharmacol 183: 111-127.
    • (2008) Handb Exp Pharmacol , vol.183 , pp. 111-127
    • Asea, A.1
  • 13
    • 4344697308 scopus 로고    scopus 로고
    • Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide
    • Triantafilou M, Triantafilou K (2004) Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide. Biochem Soc Trans 32: 636-639.
    • (2004) Biochem Soc Trans , vol.32 , pp. 636-639
    • Triantafilou, M.1    Triantafilou, K.2
  • 14
    • 66649102550 scopus 로고    scopus 로고
    • Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4
    • Wheeler DS, Chase MA, Senft AP, Poynter SE, Wong HR, et al. (2009) Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4. Respir Res 10: 31.
    • (2009) Respir Res , vol.10 , pp. 31
    • Wheeler, D.S.1    Chase, M.A.2    Senft, A.P.3    Poynter, S.E.4    Wong, H.R.5
  • 15
    • 38449110130 scopus 로고    scopus 로고
    • Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4-and NF-{kappa}B dependent mechanism
    • Chase MA, Wheeler DS, Lierl KM, Hughes VS, Wong HR, et al. (2007) Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4-and NF-{kappa}B dependent mechanism. J Immunol 179: 6318-6324.
    • (2007) J Immunol , vol.179 , pp. 6318-6324
    • Chase, M.A.1    Wheeler, D.S.2    Lierl, K.M.3    Hughes, V.S.4    Wong, H.R.5
  • 16
    • 57749184756 scopus 로고    scopus 로고
    • Extracellular heat shock protein 90 induces interleukin-8 in vascular smooth muscle cells
    • Chung SW, Lee JH, Choi KH, Park YC, Eo SK, et al. (2009) Extracellular heat shock protein 90 induces interleukin-8 in vascular smooth muscle cells. Biochem Biophys Res Commun 378: 444-449.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 444-449
    • Chung, S.W.1    Lee, J.H.2    Choi, K.H.3    Park, Y.C.4    Eo, S.K.5
  • 17
    • 34848813826 scopus 로고    scopus 로고
    • Hsp72 release: Mechanisms and methodologies
    • Asea A (2007) Hsp72 release: mechanisms and methodologies. Methods 43: 194-198.
    • (2007) Methods , vol.43 , pp. 194-198
    • Asea, A.1
  • 18
    • 17744369711 scopus 로고    scopus 로고
    • Differential induction of the toll-like receptor 4-MyD88-dependent and-independent signaling pathways by endotoxins
    • Zughaier SM, Zimmer SM, Datta A, Carlson RW, Stephens DS (2005) Differential induction of the toll-like receptor 4-MyD88-dependent and-independent signaling pathways by endotoxins. Infect Immun 73: 2940-2950.
    • (2005) Infect Immun , vol.73 , pp. 2940-2950
    • Zughaier, S.M.1    Zimmer, S.M.2    Datta, A.3    Carlson, R.W.4    Stephens, D.S.5
  • 19
    • 77951019151 scopus 로고    scopus 로고
    • Induction of cytokines and chemokines by Toll-like receptor signaling: Strategies for control of inflammation
    • Zeytun A, Chaudhary A, Pardington P, Cary R, Gupta G (2010) Induction of cytokines and chemokines by Toll-like receptor signaling: strategies for control of inflammation. Crit Rev Immunol 30: 53-67.
    • (2010) Crit Rev Immunol , vol.30 , pp. 53-67
    • Zeytun, A.1    Chaudhary, A.2    Pardington, P.3    Cary, R.4    Gupta, G.5
  • 20
    • 0034043956 scopus 로고    scopus 로고
    • Expression chemokine, and toll-like receptor 2 and 4 gene macrophages: Deregulation of cytokine, transduction in endotoxin-tolerated mouse inhibition of lipopolysaccharideinduced signal
    • Medvedev AE, Kopydlowski KM, Vogel SN (2000) Expression chemokine, and toll-like receptor 2 and 4 gene macrophages: Deregulation of cytokine, transduction in endotoxin-tolerated mouse inhibition of lipopolysaccharideinduced signal. J Immunol 164: 5564-5574.
    • (2000) J Immunol , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 21
    • 80052374406 scopus 로고    scopus 로고
    • NF-kB cellular and molecular regulatory mechanisms and pathways: Therapeutic pattern or pseudo-regulation
    • Haddad JJ, Abdel-Karim NE (2011) NF-kB cellular and molecular regulatory mechanisms and pathways: Therapeutic pattern or pseudo-regulation. Cell Immunol 271: 5-14.
    • (2011) Cell Immunol , vol.271 , pp. 5-14
    • Haddad, J.J.1    Abdel-Karim, N.E.2
  • 22
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill LA, Bowie AG (2007) The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7: 353-364.
    • (2007) Nat Rev Immunol , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 23
    • 77249179697 scopus 로고    scopus 로고
    • Guidance for substantiating the evidence for beneficial effects of probiotics: Probiotics in chronic inflammatory bowel disease and the functional disorder irritable bowel syndrome
    • Haller D, Antoine JM, Bengmark S, Enck P, Rijkers GT, et al. (2010) Guidance for substantiating the evidence for beneficial effects of probiotics: probiotics in chronic inflammatory bowel disease and the functional disorder irritable bowel syndrome. J Nutr 140: 690S-697S.
    • (2010) J Nutr , vol.140
    • Haller, D.1    Antoine, J.M.2    Bengmark, S.3    Enck, P.4    Rijkers, G.T.5
  • 24
    • 70049095676 scopus 로고    scopus 로고
    • Prevention of TNBS-induced colitis by different Lactobacillus and Bifidobacterium strains is associated with an expansion of cdT and regulatory T cells of intestinal intraepithelial lymphocytes
    • Roselli M, Finamore A, Nuccitelli S, Carnevali P, Brigidi P, et al. (2009) Prevention of TNBS-induced colitis by different Lactobacillus and Bifidobacterium strains is associated with an expansion of cdT and regulatory T cells of intestinal intraepithelial lymphocytes. Inflamm Bow Dis 15: 1526-1536.
    • (2009) Inflamm Bow Dis , vol.15 , pp. 1526-1536
    • Roselli, M.1    Finamore, A.2    Nuccitelli, S.3    Carnevali, P.4    Brigidi, P.5
  • 25
    • 84858255145 scopus 로고    scopus 로고
    • Lactobacillus rhamnosus GG and Bifidobacterium animalis MB5 induce intestinal but not systemic antigen-specific hyporesponsiveness in ovalbumin immunized rats
    • Finamore A, Roselli M, Britti MS, Merendino N, Mengheri E (2012) Lactobacillus rhamnosus GG and Bifidobacterium animalis MB5 induce intestinal but not systemic antigen-specific hyporesponsiveness in ovalbumin immunized rats. J. Nutr. 142: 375-381.
    • (2012) J. Nutr. , vol.142 , pp. 375-381
    • Finamore, A.1    Roselli, M.2    Britti, M.S.3    Merendino, N.4    Mengheri, E.5
  • 26
    • 84874853479 scopus 로고    scopus 로고
    • Cell-free culture supernatant of Bifidobacterium breve CNCM I-4035 decreases pro-inflammatory cytokines in human dendritic cells challenged with Salmonella typhi through TLR activation
    • Bermudez-Brito M, Munoz-Quezada S, Gomez-Llorente C, Matencio E, Bernal MJ, et al. (2013) Cell-free culture supernatant of Bifidobacterium breve CNCM I-4035 decreases pro-inflammatory cytokines in human dendritic cells challenged with Salmonella typhi through TLR activation. PLoS One 8: e59370.
    • (2013) PLoS One , vol.8
    • Bermudez-Brito, M.1    Munoz-Quezada, S.2    Gomez-Llorente, C.3    Matencio, E.4    Bernal, M.J.5
  • 27
    • 84857096721 scopus 로고    scopus 로고
    • Immunobiotic Lactobacillus jensenii elicits anti-inflammatory activity in porcine intestinal epithelial cells by modulating negative regulators of the Toll-like receptor signaling pathway
    • Shimazu T, Villena J, Tohno M, Fujie H, Hosoya S, et al. (2012) Immunobiotic Lactobacillus jensenii elicits anti-inflammatory activity in porcine intestinal epithelial cells by modulating negative regulators of the Toll-like receptor signaling pathway. Infect Immun 80: 276-288.
    • (2012) Infect Immun , vol.80 , pp. 276-288
    • Shimazu, T.1    Villena, J.2    Tohno, M.3    Fujie, H.4    Hosoya, S.5
  • 28
    • 67649133045 scopus 로고    scopus 로고
    • Lactobacilli stimulate the innate immune response and modulate the TLR expression of HT29 intestinal epithelial cells in vitro
    • Vizoso Pinto MG, Rodriguez Gómez M, Seifert S, Watzl B, Holzapfel WH, et al. (2009) Lactobacilli stimulate the innate immune response and modulate the TLR expression of HT29 intestinal epithelial cells in vitro. Int J Food Microbiol 133: 86-93.
    • (2009) Int J Food Microbiol , vol.133 , pp. 86-93
    • Vizoso Pinto, M.G.1    Rodriguez Gómez, M.2    Seifert, S.3    Watzl, B.4    Holzapfel, W.H.5
  • 29
    • 37149036876 scopus 로고    scopus 로고
    • The novel porcine Lactobacillus sobrius strain protects intestinal cells from enterotoxigenic Escherichia coli K88 infection and prevents membrane barrier damage
    • Roselli M, Finamore A, Britti MS, Konstantinov SR, Smidt H, et al. (2007) The novel porcine Lactobacillus sobrius strain protects intestinal cells from enterotoxigenic Escherichia coli K88 infection and prevents membrane barrier damage. J Nutr 137: 2709-2716.
    • (2007) J Nutr , vol.137 , pp. 2709-2716
    • Roselli, M.1    Finamore, A.2    Britti, M.S.3    Konstantinov, S.R.4    Smidt, H.5
  • 30
    • 34250011553 scopus 로고    scopus 로고
    • Commensal microbiota is required for the normal development and function of the porcine host immune system and physiology
    • In: Mengheri E, editor. Kerala (India): Research Signpost
    • Konstantinov SR, Smidt H (2006) Commensal microbiota is required for the normal development and function of the porcine host immune system and physiology. In: Mengheri E, editor. Nutrition and immunity. Kerala (India): Research Signpost, p. 23-38.
    • (2006) Nutrition and Immunity , pp. 23-38
    • Konstantinov, S.R.1    Smidt, H.2
  • 31
    • 79960846404 scopus 로고    scopus 로고
    • In vitro evaluation of gastrointestinal survival of Lactobacillus amylovorus DSM 16698 alone and combined with galactooligosaccharides, milk and/or Bifidobacterium animalis subsp. Lactis Bb-12
    • Martinez RC, Aynaou AE, Albrecht S, Schols HA, De Martinis EC, et al. (2011) In vitro evaluation of gastrointestinal survival of Lactobacillus amylovorus DSM 16698 alone and combined with galactooligosaccharides, milk and/or Bifidobacterium animalis subsp. lactis Bb-12. Int J Food Microbiol 149: 152-158.
    • (2011) Int J Food Microbiol , vol.149 , pp. 152-158
    • Martinez, R.C.1    Aynaou, A.E.2    Albrecht, S.3    Schols, H.A.4    De Martinis, E.C.5
  • 32
    • 84867749654 scopus 로고    scopus 로고
    • Toxicity of deoxynivalenol and its acetylated derivatives on the intestine: Differential effects on morphology, barrier function, tight junctions proteins and MAPKinases
    • Pinton P, Tsybulskyy D, Lucioli J, Laffitte J, Callu P, et al (2012) Toxicity of deoxynivalenol and its acetylated derivatives on the intestine: differential effects on morphology, barrier function, tight junctions proteins and MAPKinases. Tox Sci 130: 180-190.
    • (2012) Tox Sci , vol.130 , pp. 180-190
    • Pinton, P.1    Tsybulskyy, D.2    Lucioli, J.3    Laffitte, J.4    Callu, P.5
  • 34
    • 0027979552 scopus 로고
    • Differential expression of sucrase-isomaltase in clones isolated from early and late passages of the cell line Caco-2: Evidence for glucose-dependent negative regulation
    • Chantret I, Rodolosse A, Barbat A, Dussaulx E, Brot-Laroche E, et al. (1994) Differential expression of sucrase-isomaltase in clones isolated from early and late passages of the cell line Caco-2: evidence for glucose-dependent negative regulation. J Cell Sci 107: 213-225.
    • (1994) J Cell Sci , vol.107 , pp. 213-225
    • Chantret, I.1    Rodolosse, A.2    Barbat, A.3    Dussaulx, E.4    Brot-Laroche, E.5
  • 35
    • 0028796713 scopus 로고
    • Characterisation of a newly isolated Caco-2 clone (TC-7), as a model of transport processes and biotransformation of drugs
    • Caro I, Boulenc X, Rousset M, Meunier V, Bourrié M, et al. (1995) Characterisation of a newly isolated Caco-2 clone (TC-7), as a model of transport processes and biotransformation of drugs. Int J Pharm 116: 147-158.
    • (1995) Int J Pharm , vol.116 , pp. 147-158
    • Caro, I.1    Boulenc, X.2    Rousset, M.3    Meunier, V.4    Bourrié, M.5
  • 36
    • 70449535870 scopus 로고    scopus 로고
    • Development of a pig jejunal explant culture for studying the gastrointestinal toxicity of the mycotoxin deoxynivalenol: Histopathological analysis
    • Kolf-Clauw M, Castellote J, Joly B, Bourges-Abella N, Raymond-Letron I, et al. (2009) Development of a pig jejunal explant culture for studying the gastrointestinal toxicity of the mycotoxin deoxynivalenol: histopathological analysis. Toxicol In Vitro 23: 1580-1584.
    • (2009) Toxicol in Vitro , vol.23 , pp. 1580-1584
    • Kolf-Clauw, M.1    Castellote, J.2    Joly, B.3    Bourges-Abella, N.4    Raymond-Letron, I.5
  • 38
    • 0030811659 scopus 로고    scopus 로고
    • Inhibition of Salmonella typhimurium adhesion to Caco-2 cell cultures by Lactobacillus strain GG spent culture supernate: Only a pH effect?
    • Lehto EM, Salminen SJ (1997) Inhibition of Salmonella typhimurium adhesion to Caco-2 cell cultures by Lactobacillus strain GG spent culture supernate: only a pH effect? FEMS Immunol Med Microbiol 18: 125-132.
    • (1997) FEMS Immunol Med Microbiol , vol.18 , pp. 125-132
    • Lehto, E.M.1    Salminen, S.J.2
  • 39
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, et al. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451.
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5
  • 40
    • 20844463064 scopus 로고    scopus 로고
    • A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease
    • Fort MM, Mozaffarian A, Stöver AG, Correia Jda S, Johnson DA, et al. (2005) A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease. J Immunol 174: 6416-6423.
    • (2005) J Immunol , vol.174 , pp. 6416-6423
    • Fort, M.M.1    Mozaffarian, A.2    Stöver, A.G.3    Correia Jda, S.4    Johnson, D.A.5
  • 41
    • 84869129239 scopus 로고    scopus 로고
    • Fish oil enhances intestinal integrity and inhibits TLR4 and NOD2 signaling pathways in weaned pigs after LPS challenge
    • Liu Y, Chen F, Odle J, Lin X, Jacobi SK, et al. (2012) Fish oil enhances intestinal integrity and inhibits TLR4 and NOD2 signaling pathways in weaned pigs after LPS challenge. J Nutr 142: 2017-2024.
    • (2012) J Nutr , vol.142 , pp. 2017-2024
    • Liu, Y.1    Chen, F.2    Odle, J.3    Lin, X.4    Jacobi, S.K.5
  • 43
    • 55949107329 scopus 로고    scopus 로고
    • Feeding of Lactobacillus sobrius reduces Escherichia coli F4 levels in the gut and promotes growth of infected piglets
    • Konstantinov SR, Smidt H, Akkermans AD, Casini L, Trevisi P, et al. (2008) Feeding of Lactobacillus sobrius reduces Escherichia coli F4 levels in the gut and promotes growth of infected piglets. FEMS Microbiol Ecol 66: 599-607.
    • (2008) FEMS Microbiol Ecol , vol.66 , pp. 599-607
    • Konstantinov, S.R.1    Smidt, H.2    Akkermans, A.D.3    Casini, L.4    Trevisi, P.5
  • 45
    • 70349227292 scopus 로고    scopus 로고
    • In vitro evaluation of Lactobacillus plantarum DSMZ 12028 as a probiotic: Emphasis on innate immunity
    • Cammarota M, De Rosa M, Stellavato A, Lamberti M, Marzaioli I, et al. (2009) In vitro evaluation of Lactobacillus plantarum DSMZ 12028 as a probiotic: emphasis on innate immunity. Int J Food Microbiol 135: 90-98.
    • (2009) Int J Food Microbiol , vol.135 , pp. 90-98
    • Cammarota, M.1    De Rosa, M.2    Stellavato, A.3    Lamberti, M.4    Marzaioli, I.5
  • 46
    • 84863254669 scopus 로고    scopus 로고
    • Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-kB signaling in the intestine
    • Liu Y, Fatheree NY, Mangalat N, Rhoads JM (2012) Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-kB signaling in the intestine. Am J Physiol Gastrointest Liver Physiol 302: G608-G617.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.302
    • Liu, Y.1    Fatheree, N.Y.2    Mangalat, N.3    Rhoads, J.M.4
  • 47
    • 40149109792 scopus 로고    scopus 로고
    • Infant intestinal Enterococcus faecalis down-regulates inflammatory responses in human intestinal cell lines
    • Wang S, Ng LH, Chow WL, Lee YK (2008) Infant intestinal Enterococcus faecalis down-regulates inflammatory responses in human intestinal cell lines. World J Gastroenterol 14: 1067-1076.
    • (2008) World J Gastroenterol , vol.14 , pp. 1067-1076
    • Wang, S.1    Ng, L.H.2    Chow, W.L.3    Lee, Y.K.4
  • 48
    • 0037096172 scopus 로고    scopus 로고
    • Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
    • Triantafilou M, Miyake K, Golenbock DT, Triantafilou K (2002) Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation. J Cell Sci 115: 2603-2611.
    • (2002) J Cell Sci , vol.115 , pp. 2603-2611
    • Triantafilou, M.1    Miyake, K.2    Golenbock, D.T.3    Triantafilou, K.4
  • 51
    • 0036510366 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor-mediated signaling by Tollip
    • Zhang G, Ghosh S (2002) Negative regulation of toll-like receptor-mediated signaling by Tollip. J Biol Chem 277: 7059-7065.
    • (2002) J Biol Chem , vol.277 , pp. 7059-7065
    • Zhang, G.1    Ghosh, S.2
  • 52
    • 31344444906 scopus 로고    scopus 로고
    • Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide
    • Didierlaurent A, Brissoni B, Velin D, Aebi N, Tardivel A, et al. (2006) Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide. Mol Cell Biol 26: 735-742.
    • (2006) Mol Cell Biol , vol.26 , pp. 735-742
    • Didierlaurent, A.1    Brissoni, B.2    Velin, D.3    Aebi, N.4    Tardivel, A.5
  • 53
    • 1842583729 scopus 로고    scopus 로고
    • Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells
    • Otte JM, Cario E, Podolsky DK (2004) Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 126: 1054-1070.
    • (2004) Gastroenterology , vol.126 , pp. 1054-1070
    • Otte, J.M.1    Cario, E.2    Podolsky, D.K.3
  • 54
    • 33748317968 scopus 로고    scopus 로고
    • Sepsisinduced suppression of lung innate immunity is mediated by IRAK-M
    • Deng JC, Cheng G, Newstead MW, Zeng X, Kobayashi K, et al. (2006) Sepsisinduced suppression of lung innate immunity is mediated by IRAK-M. J Clin Invest 116: 2532-2542.
    • (2006) J Clin Invest , vol.116 , pp. 2532-2542
    • Deng, J.C.1    Cheng, G.2    Newstead, M.W.3    Zeng, X.4    Kobayashi, K.5
  • 55
    • 68149169644 scopus 로고    scopus 로고
    • TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia
    • Lagler H, Sharif O, Haslinger I, Matt U, Stich K, et al. (2009) TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J Immunol 183: 2027-2036.
    • (2009) J Immunol , vol.183 , pp. 2027-2036
    • Lagler, H.1    Sharif, O.2    Haslinger, I.3    Matt, U.4    Stich, K.5
  • 56
    • 84874610753 scopus 로고    scopus 로고
    • Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia colimediated inflammation
    • Takanashi N, Tomosada Y, Villena J, Murata K, Takahashi T, et al. (2013) Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia colimediated inflammation. BMC Microbiol 13: 54.
    • (2013) BMC Microbiol , vol.13 , pp. 54
    • Takanashi, N.1    Tomosada, Y.2    Villena, J.3    Murata, K.4    Takahashi, T.5
  • 57
    • 84890122446 scopus 로고    scopus 로고
    • Advanced application of porcine intestinal epithelial cells for the selection of immunobiotics modulating toll-like receptor 3-mediated inflammation
    • Hosoya S, Villena J, Chiba E, Shimazu T, Suda Y, et al. (2013) Advanced application of porcine intestinal epithelial cells for the selection of immunobiotics modulating toll-like receptor 3-mediated inflammation. J Microbiol Immunol Infect 46: 474-481.
    • (2013) J Microbiol Immunol Infect , vol.46 , pp. 474-481
    • Hosoya, S.1    Villena, J.2    Chiba, E.3    Shimazu, T.4    Suda, Y.5
  • 58
    • 78650404485 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine
    • Biswas A, Wilmanski J, Forsman H, Hrncir T, Hao LH (2011) Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine. Eur J Immunol 41: 182-194.
    • (2011) Eur J Immunol , vol.41 , pp. 182-194
    • Biswas, A.1    Wilmanski, J.2    Forsman, H.3    Hrncir, T.4    Hao, L.H.5
  • 59
    • 84863539789 scopus 로고    scopus 로고
    • Immunobiotic Lactobacillus jensenii modulates the Toll-like receptor 4-induced inflammatory response via negative regulation in porcine antigen-presenting cells
    • Villena J, Suzuki R, Fujie H, Chiba E, Takahashi T, et al. (2012) Immunobiotic Lactobacillus jensenii modulates the Toll-like receptor 4-induced inflammatory response via negative regulation in porcine antigen-presenting cells. Clin Vaccine Immunol 19: 1038-1053.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 1038-1053
    • Villena, J.1    Suzuki, R.2    Fujie, H.3    Chiba, E.4    Takahashi, T.5
  • 60
    • 84881502873 scopus 로고    scopus 로고
    • Lactobacillus plantarum reduces Streptococcus pyogenes virulence by modulating the IL-17, IL-23 and Toll-like receptor 2/4 expressions in human epithelial cells
    • Rizzo A, Losacco A, Carratelli CR, Domenico MD, Bevilacqua N (2013) Lactobacillus plantarum reduces Streptococcus pyogenes virulence by modulating the IL-17, IL-23 and Toll-like receptor 2/4 expressions in human epithelial cells. Int Immunopharmacol 17: 453-461.
    • (2013) Int Immunopharmacol , vol.17 , pp. 453-461
    • Rizzo, A.1    Losacco, A.2    Carratelli, C.R.3    Domenico, M.D.4    Bevilacqua, N.5
  • 61
    • 34247235029 scopus 로고    scopus 로고
    • Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
    • Cario E, Gerken G, Podolsky DK (2007) Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology 132: 1359-1374.
    • (2007) Gastroenterology , vol.132 , pp. 1359-1374
    • Cario, E.1    Gerken, G.2    Podolsky, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.