-
1
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas S, Rand MD, Lake RJ, 1999 Notch signaling: cell fate control and signal integration in development. Science 284: 770-776.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
2
-
-
0032242705
-
Notch signalling and the control of cell fate choices in vertebrates
-
Lewis J, 1998 Notch signalling and the control of cell fate choices in vertebrates. Semin Cell Dev Biol 9: 583-589.
-
(1998)
Semin Cell Dev Biol
, vol.9
, pp. 583-589
-
-
Lewis, J.1
-
3
-
-
0032241789
-
Notch signalling in Drosophila: Three ways to use a pathway
-
Bray S, 1998 Notch signalling in Drosophila: three ways to use a pathway. Semin Cell Dev Biol 9: 591-597.
-
(1998)
Semin Cell Dev Biol
, vol.9
, pp. 591-597
-
-
Bray, S.1
-
5
-
-
1242265691
-
Regulation of notch signaling activity
-
Schweisguth F, 2004 Regulation of notch signaling activity. Curr Biol 14: R129-138.
-
(2004)
Curr Biol
, vol.14
-
-
Schweisguth, F.1
-
6
-
-
33845299568
-
Notch, a universal arbiter of cell fate decisions
-
Ehebauer M, Hayward P, Arias AM, 2006 Notch, a universal arbiter of cell fate decisions. Science 314: 1414-1415.
-
(2006)
Science
, vol.314
, pp. 1414-1415
-
-
Ehebauer, M.1
Hayward, P.2
Arias, A.M.3
-
8
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan R, Ilagan MX, 2009 The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137: 216-233.
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
9
-
-
42449129791
-
Functions of Ofucosyltransferase in Notch trafficking and signaling: Towards the end of a controversy?
-
Vodovar N, Schweisguth F, 2008 Functions of Ofucosyltransferase in Notch trafficking and signaling: towards the end of a controversy? J Biol 7: 7.
-
(2008)
J Biol
, vol.7
, pp. 7
-
-
Vodovar, N.1
Schweisguth, F.2
-
10
-
-
36949031706
-
Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells
-
Zhang XP, Zheng G, Zou L, et al, 2008 Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells. Mol Cell Biochem 307: 101-108.
-
(2008)
Mol Cell Biochem
, vol.307
, pp. 101-108
-
-
Zhang, X.P.1
Zheng, G.2
Zou, L.3
-
12
-
-
33947241465
-
SnapShot: Notch signaling pathway
-
Ilagan MX, Kopan R, 2007 SnapShot: notch signaling pathway. Cell 128: 1246.
-
(2007)
Cell
, vol.128
, pp. 1246
-
-
Ilagan, M.X.1
Kopan, R.2
-
13
-
-
0141995063
-
Glycosylation regulates Notch signalling
-
Haines N, Irvine KD, 2003 Glycosylation regulates Notch signalling. Nat Rev Mol Cell Biol 4: 786-797.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 786-797
-
-
Haines, N.1
Irvine, K.D.2
-
14
-
-
34250878429
-
Notch signaling in normal and disease States: Possible therapies related to glycosylation
-
Rampal R, Luther KB, Haltiwanger RS, 2007 Notch signaling in normal and disease States: possible therapies related to glycosylation. Curr Mol Med 7: 427-445.
-
(2007)
Curr Mol Med
, vol.7
, pp. 427-445
-
-
Rampal, R.1
Luther, K.B.2
Haltiwanger, R.S.3
-
15
-
-
35549010538
-
Regulation of Notch signaling by glycosylation
-
Stanley P, 2007 Regulation of Notch signaling by glycosylation. Curr Opin Struct Biol 17: 530-535.
-
(2007)
Curr Opin Struct Biol
, vol.17
, pp. 530-535
-
-
Stanley, P.1
-
16
-
-
36349024875
-
Active gamma-secretase complexes contain only one of each component
-
Sato T, Diehl TS, Narayanan S, et al, 2007 Active gamma-secretase complexes contain only one of each component. J Biol Chem 282: 33985-33993.
-
(2007)
J Biol Chem
, vol.282
, pp. 33985-33993
-
-
Sato, T.1
Diehl, T.S.2
Narayanan, S.3
-
17
-
-
0042204967
-
Transcriptional mechanisms in osteoblast differentiation and bone formation
-
Nakashima K, de Crombrugghe B, 2003 Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends Genet 19: 458-466.
-
(2003)
Trends Genet
, vol.19
, pp. 458-466
-
-
Nakashima, K.1
de Crombrugghe, B.2
-
18
-
-
0036225281
-
Reaching a genetic and molecular understanding of skeletal development
-
Karsenty G, Wagner EF, 2002 Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2: 389-406.
-
(2002)
Dev Cell
, vol.2
, pp. 389-406
-
-
Karsenty, G.1
Wagner, E.F.2
-
19
-
-
77951229591
-
RBPjkappadependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
-
Dong Y, Jesse AM, Kohn A, et al, 2010 RBPjkappadependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development. Development 137: 1461-1471.
-
(2010)
Development
, vol.137
, pp. 1461-1471
-
-
Dong, Y.1
Jesse, A.M.2
Kohn, A.3
-
20
-
-
0036076389
-
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer
-
Logan M, Martin JF, Nagy A, Lobe C, Olson EN, Tabin CJ, 2002 Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis 33: 77-80.
-
(2002)
Genesis
, vol.33
, pp. 77-80
-
-
Logan, M.1
Martin, J.F.2
Nagy, A.3
Lobe, C.4
Olson, E.N.5
Tabin, C.J.6
-
21
-
-
40449084522
-
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
-
Hilton MJ, Tu X, Wu X, et al, 2008 Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med 14: 306-314.
-
(2008)
Nat Med
, vol.14
, pp. 306-314
-
-
Hilton, M.J.1
Tu, X.2
Wu, X.3
-
22
-
-
0030899814
-
SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene
-
Lefebvre V, Huang W, Harley VR, Goodfellow PN, de Crombrugghe B, 1997 SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol 17: 2336-2346.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2336-2346
-
-
Lefebvre, V.1
Huang, W.2
Harley, V.R.3
Goodfellow, P.N.4
de Crombrugghe, B.5
-
24
-
-
51849085670
-
Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site
-
Grogan SP, Olee T, Hiraoka K, Lotz MK, 2008 Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site. Arthritis Rheum 58: 2754-2763.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2754-2763
-
-
Grogan, S.P.1
Olee, T.2
Hiraoka, K.3
Lotz, M.K.4
-
25
-
-
84873974298
-
Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9
-
Chen S, Tao J, Bae Y, et al, 2013 Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9. J Bone Miner Res 28: 649-659.
-
(2013)
J Bone Miner Res
, vol.28
, pp. 649-659
-
-
Chen, S.1
Tao, J.2
Bae, Y.3
-
26
-
-
70149123248
-
Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development
-
Mead TJ, Yutzey KE, 2009 Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Proc Natl Acad Sci U S A 106: 14420-14425.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14420-14425
-
-
Mead, T.J.1
Yutzey, K.E.2
-
27
-
-
84857304426
-
Cartilagespecific RBPjkappa-dependent and-independent Notch signals regulate cartilage and bone development
-
Kohn A, Dong Y, Mirando AJ, et al, 2012 Cartilagespecific RBPjkappa-dependent and-independent Notch signals regulate cartilage and bone development. Development 139: 1198-1212.
-
(2012)
Development
, vol.139
, pp. 1198-1212
-
-
Kohn, A.1
Dong, Y.2
Mirando, A.J.3
-
28
-
-
47949130093
-
Notch inhibits osteoblast differentiation and causes osteopenia
-
Zanotti S, Smerdel-Ramoya A, Stadmeyer L, Durant D, Radtke F, Canalis E, 2008 Notch inhibits osteoblast differentiation and causes osteopenia. Endocrinology 149: 3890-3899.
-
(2008)
Endocrinology
, vol.149
, pp. 3890-3899
-
-
Zanotti, S.1
Smerdel-Ramoya, A.2
Stadmeyer, L.3
Durant, D.4
Radtke, F.5
Canalis, E.6
-
29
-
-
40449139405
-
Dimorphic effects of Notch signaling in bone homeostasis
-
Engin F, Yao Z, Yang T, et al, 2008 Dimorphic effects of Notch signaling in bone homeostasis. Nat Med 14: 299-305.
-
(2008)
Nat Med
, vol.14
, pp. 299-305
-
-
Engin, F.1
Yao, Z.2
Yang, T.3
-
30
-
-
84872701013
-
Osteoblast lineage-specific effects of notch activation in the skeleton
-
Canalis E, Parker K, Feng JQ, Zanotti S, 2013 Osteoblast lineage-specific effects of notch activation in the skeleton. Endocrinology 154: 623-634.
-
(2013)
Endocrinology
, vol.154
, pp. 623-634
-
-
Canalis, E.1
Parker, K.2
Feng, J.Q.3
Zanotti, S.4
-
31
-
-
0036133690
-
Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage
-
Kalajzic I, Kalajzic Z, Kaliterna M, et al, 2002 Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage. J Bone Miner Res 17: 15-25.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 15-25
-
-
Kalajzic, I.1
Kalajzic, Z.2
Kaliterna, M.3
-
32
-
-
21644486143
-
Expression profile of osteoblast lineage at defined stages of differentiation
-
Kalajzic I, Staal A, Yang WP, et al, 2005 Expression profile of osteoblast lineage at defined stages of differentiation. J Biol Chem 280: 24618-24626.
-
(2005)
J Biol Chem
, vol.280
, pp. 24618-24626
-
-
Kalajzic, I.1
Staal, A.2
Yang, W.P.3
-
33
-
-
4444246433
-
Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity
-
Zamurovic N, Cappellen D, Rohner D, Susa M, 2004 Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity. J Biol Chem 279: 37704-37715.
-
(2004)
J Biol Chem
, vol.279
, pp. 37704-37715
-
-
Zamurovic, N.1
Cappellen, D.2
Rohner, D.3
Susa, M.4
-
34
-
-
0345688655
-
Notch 1 impairs osteoblastic cell differentiation
-
Sciaudone M, Gazzerro E, Priest L, Delany AM, Canalis E, 2003 Notch 1 impairs osteoblastic cell differentiation. Endocrinology 144: 5631-5639.
-
(2003)
Endocrinology
, vol.144
, pp. 5631-5639
-
-
Sciaudone, M.1
Gazzerro, E.2
Priest, L.3
Delany, A.M.4
Canalis, E.5
-
35
-
-
0036155343
-
Stimulation of osteoblastic cell differentiation by Notch
-
Tezuka K, Yasuda M, Watanabe N, et al, 2002 Stimulation of osteoblastic cell differentiation by Notch. J Bone Miner Res 17: 231-239.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 231-239
-
-
Tezuka, K.1
Yasuda, M.2
Watanabe, N.3
-
36
-
-
18144384703
-
Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling
-
Nobta M, Tsukazaki T, Shibata Y, et al, 2005 Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling. J Biol Chem 280: 15842-15848.
-
(2005)
J Biol Chem
, vol.280
, pp. 15842-15848
-
-
Nobta, M.1
Tsukazaki, T.2
Shibata, Y.3
-
37
-
-
33646550902
-
Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling
-
Deregowski V, Gazzerro E, Priest L, Rydziel S, Canalis E, 2006 Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling. J Biol Chem 281: 6203-6210.
-
(2006)
J Biol Chem
, vol.281
, pp. 6203-6210
-
-
Deregowski, V.1
Gazzerro, E.2
Priest, L.3
Rydziel, S.4
Canalis, E.5
-
38
-
-
0034614616
-
The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1
-
McLarren KW, Lo R, Grbavec D, Thirunavukkarasu K, Karsenty G, Stifani S, 2000 The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1. J Biol Chem 275: 530-538.
-
(2000)
J Biol Chem
, vol.275
, pp. 530-538
-
-
McLarren, K.W.1
Lo, R.2
Grbavec, D.3
Thirunavukkarasu, K.4
Karsenty, G.5
Stifani, S.6
-
39
-
-
28844466310
-
The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin
-
Shen Q, Christakos S, 2005 The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin. J Biol Chem 280: 40589-40598.
-
(2005)
J Biol Chem
, vol.280
, pp. 40589-40598
-
-
Shen, Q.1
Christakos, S.2
-
40
-
-
70350170420
-
The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells
-
Zhang Y, Lian JB, Stein JL, van Wijnen AJ, Stein GS, 2009 The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells. J Cell Biochem 108: 651-659.
-
(2009)
J Cell Biochem
, vol.108
, pp. 651-659
-
-
Zhang, Y.1
Lian, J.B.2
Stein, J.L.3
van Wijnen, A.J.4
Stein, G.S.5
-
41
-
-
33947497852
-
Osteoclasts: What do they do and how do they do it?
-
Teitelbaum SL, 2007 Osteoclasts: what do they do and how do they do it? Am J Pathol 170: 427-435.
-
(2007)
Am J Pathol
, vol.170
, pp. 427-435
-
-
Teitelbaum, S.L.1
-
42
-
-
42749095897
-
NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells
-
Bai S, Kopan R, Zou W, et al, 2008 NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J Biol Chem 283: 6509-6518.
-
(2008)
J Biol Chem
, vol.283
, pp. 6509-6518
-
-
Bai, S.1
Kopan, R.2
Zou, W.3
-
43
-
-
0037443389
-
Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells
-
Yamada T, Yamazaki H, Yamane T, et al, 2003 Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells. Blood 101: 2227-2234.
-
(2003)
Blood
, vol.101
, pp. 2227-2234
-
-
Yamada, T.1
Yamazaki, H.2
Yamane, T.3
-
44
-
-
53549111642
-
The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis
-
Fukushima H, Nakao A, Okamoto F, et al, 2008 The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis. Mol Cell Biol 28: 6402-6412.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6402-6412
-
-
Fukushima, H.1
Nakao, A.2
Okamoto, F.3
-
45
-
-
78951492338
-
HES1 (hairy and enhancer of split 1) is a determinant of bone mass
-
Zanotti S, Smerdel-Ramoya A, Canalis E, 2011 HES1 (hairy and enhancer of split 1) is a determinant of bone mass. J Biol Chem 286: 2648-2657.
-
(2011)
J Biol Chem
, vol.286
, pp. 2648-2657
-
-
Zanotti, S.1
Smerdel-Ramoya, A.2
Canalis, E.3
-
46
-
-
77952765408
-
Autosomal dominant spondylocostal dysostosis in three generations of a Macedonian family: Negative mutation analysis of DLL3, MESP2, HES7, and LFNG
-
Gucev ZS, Tasic V, Pop-Jordanova N, et al, 2010 Autosomal dominant spondylocostal dysostosis in three generations of a Macedonian family: Negative mutation analysis of DLL3, MESP2, HES7, and LFNG. Am J Med Genet A 152A: 1378-1382.
-
(2010)
Am J Med Genet A
, vol.152 A
, pp. 1378-1382
-
-
Gucev, Z.S.1
Tasic, V.2
Pop-Jordanova, N.3
-
47
-
-
0013985215
-
A syndrome of bizarre vertebral anomalies
-
Lavy NW, Palmer CG, Merritt AD, 1966 A syndrome of bizarre vertebral anomalies. J Pediatr 69: 1121-1125.
-
(1966)
J Pediatr
, vol.69
, pp. 1121-1125
-
-
Lavy, N.W.1
Palmer, C.G.2
Merritt, A.D.3
-
48
-
-
0034028904
-
Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis
-
Bulman MP, Kusumi K, Frayling TM, et al, 2000 Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nat Genet 24: 438-441.
-
(2000)
Nat Genet
, vol.24
, pp. 438-441
-
-
Bulman, M.P.1
Kusumi, K.2
Frayling, T.M.3
-
49
-
-
0030850751
-
Mesp2: A novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation
-
Saga Y, Hata N, Koseki H, Taketo MM, 1997 Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev 11: 1827-1839.
-
(1997)
Genes Dev
, vol.11
, pp. 1827-1839
-
-
Saga, Y.1
Hata, N.2
Koseki, H.3
Taketo, M.M.4
-
50
-
-
84872186104
-
Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: A model of spondylocostal dysostosis and spondylothoracic dysostosis
-
Makino Y, Takahashi Y, Tanabe R, et al, 2013 Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone 53: 248-258.
-
(2013)
Bone
, vol.53
, pp. 248-258
-
-
Makino, Y.1
Takahashi, Y.2
Tanabe, R.3
-
51
-
-
29244458644
-
Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype
-
Sparrow DB, Chapman G, Wouters MA, et al, 2006 Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype. Am J Hum Genet 78: 28-37.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 28-37
-
-
Sparrow, D.B.1
Chapman, G.2
Wouters, M.A.3
-
52
-
-
80051676415
-
Reprint of mutation of the fucosespecific beta1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine
-
Dunwoodie SL, 2009 Reprint of mutation of the fucosespecific beta1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine. Biochim Biophys Acta 1792: 862-873.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 862-873
-
-
Dunwoodie, S.L.1
-
53
-
-
58649110008
-
Mutation of the fucose-specific beta1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine
-
Dunwoodie SL, 2009 Mutation of the fucose-specific beta1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine. Biochim Biophys Acta 1792: 100-111.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 100-111
-
-
Dunwoodie, S.L.1
-
54
-
-
0036267319
-
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice
-
Zhang N, Norton CR, Gridley T, 2002 Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice. Genesis 33: 21-28.
-
(2002)
Genesis
, vol.33
, pp. 21-28
-
-
Zhang, N.1
Norton, C.R.2
Gridley, T.3
-
55
-
-
3142679387
-
Dll3 pudgy mutation differentially disrupts dynamic expression of somite genes
-
Kusumi K, Mimoto MS, Covello KL, Beddington RS, Krumlauf R, Dunwoodie SL, 2004 Dll3 pudgy mutation differentially disrupts dynamic expression of somite genes. Genesis 39: 115-121.
-
(2004)
Genesis
, vol.39
, pp. 115-121
-
-
Kusumi, K.1
Mimoto, M.S.2
Covello, K.L.3
Beddington, R.S.4
Krumlauf, R.5
Dunwoodie, S.L.6
-
56
-
-
56049123626
-
Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis
-
Sparrow DB, Guillen-Navarro E, Fatkin D, Dunwoodie SL, 2008 Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis. Hum Mol Genet 17: 3761-3766.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3761-3766
-
-
Sparrow, D.B.1
Guillen-Navarro, E.2
Fatkin, D.3
Dunwoodie, S.L.4
-
57
-
-
77952674210
-
Two novel missense mutations in HAIR Y-AND-ENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis
-
Sparrow DB, Sillence D, Wouters MA, Turnpenny PD, Dunwoodie SL, 2010 Two novel missense mutations in HAIR Y-AND-ENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis. Eur J Hum Genet 18: 674-679.
-
(2010)
Eur J Hum Genet
, vol.18
, pp. 674-679
-
-
Sparrow, D.B.1
Sillence, D.2
Wouters, M.A.3
Turnpenny, P.D.4
Dunwoodie, S.L.5
-
58
-
-
0023148932
-
Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): Review of 80 cases
-
Alagille D, Estrada A, Hadchouel M, Gautier M, Odievre M, Dommergues JP, 1987 Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): review of 80 cases. J Pediatr 110: 195-200.
-
(1987)
J Pediatr
, vol.110
, pp. 195-200
-
-
Alagille, D.1
Estrada, A.2
Hadchouel, M.3
Gautier, M.4
Odievre, M.5
Dommergues, J.P.6
-
59
-
-
0035864903
-
Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome
-
Morrissette JD, Colliton RP, Spinner NB, 2001 Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome. Hum Mol Genet 10: 405-413.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 405-413
-
-
Morrissette, J.D.1
Colliton, R.P.2
Spinner, N.B.3
-
61
-
-
0036339631
-
A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency
-
McCright B, Lozier J, Gridley T, 2002 A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development 129: 1075-1082.
-
(2002)
Development
, vol.129
, pp. 1075-1082
-
-
McCright, B.1
Lozier, J.2
Gridley, T.3
-
62
-
-
84861752643
-
Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients
-
Humphreys R, Zheng W, Prince LS, et al, 2012 Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients. Hum Mol Genet 21: 1374-1383.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 1374-1383
-
-
Humphreys, R.1
Zheng, W.2
Prince, L.S.3
-
63
-
-
0033017848
-
Features of Alagille syndrome in 92 patients: Frequency and relation to prognosis
-
Emerick KM, Rand EB, Goldmuntz E, Krantz ID, Spinner NB, Piccoli DA, 1999 Features of Alagille syndrome in 92 patients: frequency and relation to prognosis. Hepatology 29: 822-829.
-
(1999)
Hepatology
, vol.29
, pp. 822-829
-
-
Emerick, K.M.1
Rand, E.B.2
Goldmuntz, E.3
Krantz, I.D.4
Spinner, N.B.5
Piccoli, D.A.6
-
64
-
-
0018628024
-
Arteriohepatic dysplasia: A benign syndrome of intrahepatic cholestasis with multiple organ involvement
-
Riely CA, Cotlier E, Jensen PS, Klatskin G, 1979 Arteriohepatic dysplasia: a benign syndrome of intrahepatic cholestasis with multiple organ involvement. Ann Intern Med 91: 520-527.
-
(1979)
Ann Intern Med
, vol.91
, pp. 520-527
-
-
Riely, C.A.1
Cotlier, E.2
Jensen, P.S.3
Klatskin, G.4
-
66
-
-
76249108602
-
Association of JAG1 with bone mineral density and osteoporotic fractures: A genome-wide association study and followup replication studies
-
Kung AW, Xiao SM, Cherny S, et al, 2010 Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and followup replication studies. Am J Hum Genet 86: 229-239.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 229-239
-
-
Kung, A.W.1
Xiao, S.M.2
Cherny, S.3
-
67
-
-
79953197889
-
Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss
-
Simpson MA, Irving MD, Asilmaz E, et al, 2011 Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss. Nat Genet 43: 303-305.
-
(2011)
Nat Genet
, vol.43
, pp. 303-305
-
-
Simpson, M.A.1
Irving, M.D.2
Asilmaz, E.3
-
68
-
-
0037660714
-
Hajdu-Cheney syndrome (acroosteolysis): A case report of dental interest
-
Antoniades K, Kaklamanos E, Kavadia S, Hatzistilianou M, Antoniades V, 2003 Hajdu-Cheney syndrome (acroosteolysis): a case report of dental interest. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95: 725-731.
-
(2003)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
, vol.95
, pp. 725-731
-
-
Antoniades, K.1
Kaklamanos, E.2
Kavadia, S.3
Hatzistilianou, M.4
Antoniades, V.5
-
69
-
-
0035873855
-
Hajdu--Cheney syndrome: Evolution of phenotype and clinical problems
-
Brennan AM, Pauli RM, 2001 Hajdu--Cheney syndrome: evolution of phenotype and clinical problems. Am J Med Genet 100: 292-310.
-
(2001)
Am J Med Genet
, vol.100
, pp. 292-310
-
-
Brennan, A.M.1
Pauli, R.M.2
-
70
-
-
0022543424
-
Idiopathic familial acroosteolysis: Histomorphometric study of bone and literature review of the Hajdu-Cheney syndrome
-
Udell J, Schumacher HR, Jr., Kaplan F, Fallon MD, 1986 Idiopathic familial acroosteolysis: histomorphometric study of bone and literature review of the Hajdu-Cheney syndrome. Arthritis Rheum 29: 1032-1038.
-
(1986)
Arthritis Rheum
, vol.29
, pp. 1032-1038
-
-
Udell, J.1
Schumacher Jr., H.R.2
Kaplan, F.3
Fallon, M.D.4
-
71
-
-
0017250083
-
The acro-osteolysis syndrome: Morphologic and biochemical studies
-
Brown DM, Bradford DS, Gorlin RJ, et al, 1976 The acro-osteolysis syndrome: Morphologic and biochemical studies. J Pediatr 88: 573-580.
-
(1976)
J Pediatr
, vol.88
, pp. 573-580
-
-
Brown, D.M.1
Bradford, D.S.2
Gorlin, R.J.3
-
72
-
-
84867480212
-
Two-year cyclic infusion of pamidronate improves bone mass density and eliminates risk of fractures in a girl with osteoporosis due to Hajdu-Cheney syndrome
-
Galli-Tsinopoulou A, Kyrgios I, Giza S, Giannopoulou EM, Maggana I, Laliotis N, 2012 Two-year cyclic infusion of pamidronate improves bone mass density and eliminates risk of fractures in a girl with osteoporosis due to Hajdu-Cheney syndrome. Minerva Endocrinol 37: 283-289.
-
(2012)
Minerva Endocrinol
, vol.37
, pp. 283-289
-
-
Galli-Tsinopoulou, A.1
Kyrgios, I.2
Giza, S.3
Giannopoulou, E.M.4
Maggana, I.5
Laliotis, N.6
-
73
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng AP, Ferrando AA, Lee W, et al, 2004 Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306: 269-271.
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
-
74
-
-
33644782668
-
Recent insights into the role of Notch signaling in tumorigenesis
-
Leong KG, Karsan A, 2006 Recent insights into the role of Notch signaling in tumorigenesis. Blood 107: 2223-2233.
-
(2006)
Blood
, vol.107
, pp. 2223-2233
-
-
Leong, K.G.1
Karsan, A.2
-
75
-
-
64549149292
-
Notch signaling contributes to the pathogenesis of human osteosarcomas
-
Engin F, Bertin T, Ma O, et al, 2009 Notch signaling contributes to the pathogenesis of human osteosarcomas. Hum Mol Genet 18: 1464-1470.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1464-1470
-
-
Engin, F.1
Bertin, T.2
Ma, O.3
-
76
-
-
49649103793
-
Critical role of notch signaling in osteosarcoma invasion and metastasis
-
Zhang P, Yang Y, Zweidler-McKay PA, Hughes DP, 2008 Critical role of notch signaling in osteosarcoma invasion and metastasis. Clin Cancer Res 14: 2962-2969.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2962-2969
-
-
Zhang, P.1
Yang, Y.2
Zweidler-McKay, P.A.3
Hughes, D.P.4
-
77
-
-
77956508736
-
Notch3 in human breast cancer cell lines regulates osteoblast-cancer cell interactions and osteolytic bone metastasis
-
Zhang Z, Wang H, Ikeda S, et al, 2010 Notch3 in human breast cancer cell lines regulates osteoblast-cancer cell interactions and osteolytic bone metastasis. Am J Pathol 177: 1459-1469.
-
(2010)
Am J Pathol
, vol.177
, pp. 1459-1469
-
-
Zhang, Z.1
Wang, H.2
Ikeda, S.3
-
78
-
-
79751472667
-
Tumorderived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
Sethi N, Dai X, Winter CG, Kang Y, 2011 Tumorderived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell 19: 192-205.
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
79
-
-
33845877157
-
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
-
Noguera-Troise I, Daly C, Papadopoulos NJ, et al, 2006 Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature 444: 1032-1037.
-
(2006)
Nature
, vol.444
, pp. 1032-1037
-
-
Noguera-Troise, I.1
Daly, C.2
Papadopoulos, N.J.3
-
80
-
-
0242456129
-
Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
-
Nickoloff BJ, Osborne BA, Miele L, 2003 Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene 22: 6598-6608.
-
(2003)
Oncogene
, vol.22
, pp. 6598-6608
-
-
Nickoloff, B.J.1
Osborne, B.A.2
Miele, L.3
|