MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 17, 2014, Pages 6335-6340

  Romaker, Daniel ^a,b   Kumar, Vikash ^a   Cerqueira, Débora M ^a   Cox, Ryan M ^a   Wessely, Oliver ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Amphibian; Frog; Organogenesis; Pronephros

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DICER; DOUBLE STRANDED RNA; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MICRORNA; PROTEIN; PROTEIN E6; PROTEIN KINASE B; PROTEIN S6; RAPAMYCIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SMALL UNTRANSLATED RNA; SOMATOMEDIN B; TUBEROUS SCLEROSIS 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOGENESIS; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE SILENCING; KIDNEY DEVELOPMENT; KIDNEY PROXIMAL TUBULE; KIDNEY SIZE; KIDNEY TUBULE CELL; MITOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RANA TEMPORARIA; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; UPREGULATION; XENOPUS;

AMPHIBIAN; FROG; ORGANOGENESIS; PRONEPHROS;

ANIMALS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSULIN; INSULIN-LIKE GROWTH FACTOR II; KIDNEY; KIDNEY TUBULES, PROXIMAL; LLC-PK1 CELLS; MICRORNAS; MULTIPROTEIN COMPLEXES; ORGAN SIZE; SIGNAL TRANSDUCTION; SWINE; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; XENOPUS;

EID: 84899628592     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1320577111     Document Type: Article

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