Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity

Nature Communications

Volumn 5, Issue , 2014, Pages

  Puumalainen, Marjo Riitta ^a   Lessel, Davor ^b   Rüthemann, Peter ^a   Kaczmarek, Nina ^a   Bachmann, Karin ^a   Ramadan, Kristijan ^a,c   Naegeli, Hanspeter ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF ULM   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P97; UBIQUITIN; CHROMATIN; DDB2 PROTEIN, HUMAN; DNA BINDING PROTEIN; PRIMER DNA; SMALL INTERFERING RNA; XPC PROTEIN, HUMAN;

CHROMOSOME; DISEASE INCIDENCE; DNA; GENE EXPRESSION; GENOTOXICITY; HOMEOSTASIS; PROTEIN; SKIN;

ARTICLE; CHROMATIN; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; EXCISION REPAIR; GENE OVEREXPRESSION; GENOME; GENOMIC INSTABILITY; GENOTOXICITY; HOMEOSTASIS; HUMAN; HUMAN CELL; RECOGNITION; SENSOR; ULTRAVIOLET RADIATION; CFU COUNTING; DNA REPAIR; FLUORESCENCE MICROSCOPY; GENETICS; HEK293 CELL LINE; HELA CELL LINE; IMMUNOBLOTTING; METABOLISM; MOLECULAR CLONING; PHYSIOLOGY;

CHROMATIN; CLONING, MOLECULAR; COLONY-FORMING UNITS ASSAY; DNA DAMAGE; DNA PRIMERS; DNA REPAIR; DNA-BINDING PROTEINS; GENOMIC INSTABILITY; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; RNA, SMALL INTERFERING; ULTRAVIOLET RAYS;

EID: 84899627951     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4695     Document Type: Article

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